char = A;code = 65
char = c;code = 99
char = u;code = 117
char = t;code = 116
char = e;code = 101
char = ;code = 32
char = p;code = 112
char = a;code = 97
char = n;code = 110
char = c;code = 99
char = r;code = 114
char = e;code = 101
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = t;code = 116
char = i;code = 105
char = s;code = 115
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = f;code = 102
char = i;code = 105
char = v;code = 118
char = e;code = 101
char = ;code = 32
char = E;code = 69
char = u;code = 117
char = r;code = 114
char = o;code = 111
char = p;code = 112
char = e;code = 101
char = a;code = 97
char = n;code = 110
char = ;code = 32
char = c;code = 99
char = o;code = 111
char = u;code = 117
char = n;code = 110
char = t;code = 116
char = r;code = 114
char = i;code = 105
char = e;code = 101
char = s;code = 115
char = :;code = 58
char = ;code = 32
char = e;code = 101
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = l;code = 108
char = o;code = 111
char = g;code = 103
char = y;code = 121
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = m;code = 109
char = o;code = 111
char = r;code = 114
char = t;code = 116
char = a;code = 97
char = l;code = 108
char = i;code = 105
char = t;code = 116
char = y;code = 121
char = .;code = 46
result sql = Acute pancreatitis in five European countries: etiology and mortality.
Acute pancreatitis in five European countries: etiology and mortality.
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = I;code = 73
char = N;code = 78
char = T;code = 84
char = R;code = 82
char = O;code = 79
char = D;code = 68
char = U;code = 85
char = C;code = 67
char = T;code = 84
char = I;code = 73
char = O;code = 79
char = N;code = 78
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
char = b;code = 98
char = >;code = 62
char = I;code = 73
char = n;code = 110
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = c;code = 99
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = ;code = 32
char = y;code = 121
char = e;code = 101
char = a;code = 97
char = r;code = 114
char = s;code = 115
char = ,;code = 44
char = ;code = 32
char = m;code = 109
char = a;code = 97
char = n;code = 110
char = y;code = 121
char = ;code = 32
char = a;code = 97
char = d;code = 100
char = v;code = 118
char = a;code = 97
char = n;code = 110
char = c;code = 99
char = e;code = 101
char = s;code = 115
char = ;code = 32
char = h;code = 104
char = a;code = 97
char = v;code = 118
char = e;code = 101
char = ;code = 32
char = b;code = 98
char = e;code = 101
char = e;code = 101
char = n;code = 110
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char = m;code = 109
char = a;code = 97
char = d;code = 100
char = e;code = 101
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = d;code = 100
char = i;code = 105
char = a;code = 97
char = g;code = 103
char = n;code = 110
char = o;code = 111
char = s;code = 115
char = i;code = 105
char = s;code = 115
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = t;code = 116
char = r;code = 114
char = e;code = 101
char = a;code = 97
char = t;code = 116
char = m;code = 109
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = a;code = 97
char = c;code = 99
char = u;code = 117
char = t;code = 116
char = e;code = 101
char = ;code = 32
char = p;code = 112
char = a;code = 97
char = n;code = 110
char = c;code = 99
char = r;code = 114
char = e;code = 101
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = t;code = 116
char = i;code = 105
char = s;code = 115
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = a;code = 97
char = t;code = 116
char = ;code = 32
char = h;code = 104
char = a;code = 97
char = v;code = 118
char = e;code = 101
char = ;code = 32
char = l;code = 108
char = e;code = 101
char = a;code = 97
char = d;code = 100
char = ;code = 32
char = t;code = 116
char = o;code = 111
char = ;code = 32
char = a;code = 97
char = ;code = 32
char = s;code = 115
char = i;code = 105
char = g;code = 103
char = n;code = 110
char = i;code = 105
char = f;code = 102
char = i;code = 105
char = c;code = 99
char = a;code = 97
char = n;code = 110
char = t;code = 116
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = d;code = 100
char = u;code = 117
char = c;code = 99
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = b;code = 98
char = o;code = 111
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = m;code = 109
char = o;code = 111
char = r;code = 114
char = b;code = 98
char = i;code = 105
char = d;code = 100
char = i;code = 105
char = t;code = 116
char = y;code = 121
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = m;code = 109
char = o;code = 111
char = r;code = 114
char = t;code = 116
char = a;code = 97
char = l;code = 108
char = i;code = 105
char = t;code = 116
char = y;code = 121
char = ;;code = 59
char = ;code = 32
char = h;code = 104
char = o;code = 111
char = w;code = 119
char = e;code = 101
char = v;code = 118
char = e;code = 101
char = r;code = 114
char = ,;code = 44
char = ;code = 32
char = k;code = 107
char = n;code = 110
char = o;code = 111
char = w;code = 119
char = l;code = 108
char = e;code = 101
char = d;code = 100
char = g;code = 103
char = e;code = 101
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = e;code = 101
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = l;code = 108
char = o;code = 111
char = g;code = 103
char = y;code = 121
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = l;code = 108
char = a;code = 97
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char = i;code = 105
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = b;code = 98
char = e;code = 101
char = t;code = 116
char = w;code = 119
char = e;code = 101
char = e;code = 101
char = n;code = 110
char = ;code = 32
char = e;code = 101
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = l;code = 108
char = o;code = 111
char = g;code = 103
char = y;code = 121
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = m;code = 109
char = o;code = 111
char = r;code = 114
char = t;code = 116
char = a;code = 97
char = l;code = 108
char = i;code = 105
char = t;code = 116
char = y;code = 121
char = ;code = 32
char = i;code = 105
char = s;code = 115
char = ;code = 32
char = f;code = 102
char = a;code = 97
char = r;code = 114
char = ;code = 32
char = f;code = 102
char = r;code = 114
char = o;code = 111
char = m;code = 109
char = ;code = 32
char = c;code = 99
char = o;code = 111
char = m;code = 109
char = p;code = 112
char = l;code = 108
char = e;code = 101
char = t;code = 116
char = e;code = 101
char = .;code = 46
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = A;code = 65
char = I;code = 73
char = M;code = 77
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
char = b;code = 98
char = >;code = 62
char = T;code = 84
char = o;code = 111
char = ;code = 32
char = o;code = 111
char = b;code = 98
char = t;code = 116
char = a;code = 97
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = a;code = 97
char = ;code = 32
char = m;code = 109
char = o;code = 111
char = r;code = 114
char = e;code = 101
char = ;code = 32
char = c;code = 99
char = o;code = 111
char = m;code = 109
char = p;code = 112
char = r;code = 114
char = e;code = 101
char = h;code = 104
char = e;code = 101
char = n;code = 110
char = s;code = 115
char = i;code = 105
char = v;code = 118
char = e;code = 101
char = ;code = 32
char = v;code = 118
char = i;code = 105
char = e;code = 101
char = w;code = 119
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = e;code = 101
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = l;code = 108
char = o;code = 111
char = g;code = 103
char = y;code = 121
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = m;code = 109
char = o;code = 111
char = r;code = 114
char = t;code = 116
char = a;code = 97
char = l;code = 108
char = i;code = 105
char = t;code = 116
char = y;code = 121
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = a;code = 97
char = c;code = 99
char = u;code = 117
char = t;code = 116
char = e;code = 101
char = ;code = 32
char = p;code = 112
char = a;code = 97
char = n;code = 110
char = c;code = 99
char = r;code = 114
char = e;code = 101
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = t;code = 116
char = i;code = 105
char = s;code = 115
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = E;code = 69
char = u;code = 117
char = r;code = 114
char = o;code = 111
char = p;code = 112
char = e;code = 101
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = a;code = 97
char = n;code = 110
char = ;code = 32
char = h;code = 104
char = a;code = 97
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char = b;code = 98
char = e;code = 101
char = e;code = 101
char = n;code = 110
char = ;code = 32
char = g;code = 103
char = i;code = 105
char = v;code = 118
char = e;code = 101
char = n;code = 110
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char = b;code = 98
char = y;code = 121
char = ;code = 32
char = p;code = 112
char = r;code = 114
char = e;code = 101
char = v;code = 118
char = i;code = 105
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char = ;code = 32
char = s;code = 115
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char = g;code = 103
char = l;code = 108
char = e;code = 101
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char = e;code = 101
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char = t;code = 116
char = e;code = 101
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char = ;code = 32
char = s;code = 115
char = t;code = 116
char = u;code = 117
char = d;code = 100
char = i;code = 105
char = e;code = 101
char = s;code = 115
char = .;code = 46
char = <;code = 60
char = b;code = 98
char = r;code = 114
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char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = M;code = 77
char = E;code = 69
char = T;code = 84
char = H;code = 72
char = O;code = 79
char = D;code = 68
char = O;code = 79
char = L;code = 76
char = O;code = 79
char = G;code = 71
char = Y;code = 89
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
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char = >;code = 62
char = T;code = 84
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char = t;code = 116
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char = d;code = 100
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char = o;code = 111
char = m;code = 109
char = p;code = 112
char = r;code = 114
char = i;code = 105
char = s;code = 115
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = 1;code = 49
char = ,;code = 44
char = 0;code = 48
char = 6;code = 54
char = 8;code = 56
char = ;code = 32
char = p;code = 112
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char = s;code = 115
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char = i;code = 105
char = n;code = 110
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char = f;code = 102
char = i;code = 105
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char = E;code = 69
char = u;code = 117
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char = ;code = 32
char = c;code = 99
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char = w;code = 119
char = h;code = 104
char = o;code = 111
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char = w;code = 119
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char = a;code = 97
char = d;code = 100
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char = t;code = 116
char = t;code = 116
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = t;code = 116
char = o;code = 111
char = ;code = 32
char = h;code = 104
char = o;code = 111
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char = p;code = 112
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char = t;code = 116
char = a;code = 97
char = l;code = 108
char = s;code = 115
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char = f;code = 102
char = o;code = 111
char = r;code = 114
char = ;code = 32
char = a;code = 97
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char = t;code = 116
char = e;code = 101
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char = c;code = 99
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char = a;code = 97
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char = t;code = 116
char = i;code = 105
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char = m;code = 109
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char = J;code = 74
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char = a;code = 97
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char = 9;code = 57
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char = D;code = 68
char = e;code = 101
char = c;code = 99
char = e;code = 101
char = m;code = 109
char = b;code = 98
char = e;code = 101
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char = ;code = 32
char = 1;code = 49
char = 9;code = 57
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char = 4;code = 52
char = .;code = 46
char = ;code = 32
char = D;code = 68
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char = a;code = 97
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char = o;code = 111
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char = e;code = 101
char = a;code = 97
char = c;code = 99
char = h;code = 104
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char = p;code = 112
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char = i;code = 105
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char = ;code = 32
char = w;code = 119
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char = r;code = 114
char = e;code = 101
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char = c;code = 99
char = o;code = 111
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char = l;code = 108
char = e;code = 101
char = c;code = 99
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char = e;code = 101
char = d;code = 100
char = ;code = 32
char = o;code = 111
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char = ;code = 32
char = a;code = 97
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char = s;code = 115
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char = a;code = 97
char = n;code = 110
char = d;code = 100
char = a;code = 97
char = r;code = 114
char = d;code = 100
char = i;code = 105
char = z;code = 122
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = f;code = 102
char = o;code = 111
char = r;code = 114
char = m;code = 109
char = .;code = 46
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = R;code = 82
char = E;code = 69
char = S;code = 83
char = U;code = 85
char = L;code = 76
char = T;code = 84
char = S;code = 83
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
char = b;code = 98
char = >;code = 62
char = O;code = 79
char = f;code = 102
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
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char = 1;code = 49
char = ,;code = 44
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char = 6;code = 54
char = 8;code = 56
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char = p;code = 112
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char = s;code = 115
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char = (;code = 40
char = 6;code = 54
char = 9;code = 57
char = 2;code = 50
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char = m;code = 109
char = e;code = 101
char = n;code = 110
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char = ;code = 32
char = 3;code = 51
char = 7;code = 55
char = 6;code = 54
char = ;code = 32
char = w;code = 119
char = o;code = 111
char = m;code = 109
char = e;code = 101
char = n;code = 110
char = ;;code = 59
char = ;code = 32
char = m;code = 109
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char = a;code = 97
char = n;code = 110
char = ;code = 32
char = a;code = 97
char = g;code = 103
char = e;code = 101
char = ,;code = 44
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char = 5;code = 53
char = 2;code = 50
char = .;code = 46
char = 8;code = 56
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char = y;code = 121
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char = s;code = 115
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char = ;code = 32
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char = n;code = 110
char = g;code = 103
char = e;code = 101
char = ,;code = 44
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char = -;code = 45
char = 9;code = 57
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char = ;code = 32
char = y;code = 121
char = e;code = 101
char = a;code = 97
char = r;code = 114
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char = );code = 41
char = ,;code = 44
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char = 5;code = 53
char = 8;code = 56
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char = ;code = 32
char = h;code = 104
char = a;code = 97
char = d;code = 100
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char = e;code = 101
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char = e;code = 101
char = m;code = 109
char = a;code = 97
char = t;code = 116
char = o;code = 111
char = u;code = 117
char = s;code = 115
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char = t;code = 116
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char = C;code = 67
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char = o;code = 111
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char = e;code = 101
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char = i;code = 105
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char = a;code = 97
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char = i;code = 105
char = s;code = 115
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char = 3;code = 51
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char = ;code = 32
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char = o;code = 111
char = l;code = 108
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char = (;code = 40
char = 4;code = 52
char = 1;code = 49
char = .;code = 46
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char = ;code = 32
char = w;code = 119
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char = r;code = 114
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char = e;code = 101
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char = m;code = 109
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char = s;code = 115
char = t;code = 116
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char = t;code = 116
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char = e;code = 101
char = t;code = 116
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char = l;code = 108
char = o;code = 111
char = g;code = 103
char = i;code = 105
char = c;code = 99
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char = f;code = 102
char = a;code = 97
char = c;code = 99
char = t;code = 116
char = o;code = 111
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char = s;code = 115
char = .;code = 46
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char = n;code = 110
char = ;code = 32
char = G;code = 71
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char = r;code = 114
char = m;code = 109
char = a;code = 97
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char = t;code = 116
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char = i;code = 105
char = a;code = 97
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char = i;code = 105
char = s;code = 115
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char = ;code = 32
char = a;code = 97
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char = c;code = 99
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char = h;code = 104
char = o;code = 111
char = l;code = 108
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char = o;code = 111
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char = c;code = 99
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char = r;code = 114
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = s;code = 115
char = i;code = 105
char = m;code = 109
char = i;code = 105
char = l;code = 108
char = a;code = 97
char = r;code = 114
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char = f;code = 102
char = r;code = 114
char = e;code = 101
char = q;code = 113
char = u;code = 117
char = e;code = 101
char = n;code = 110
char = c;code = 99
char = y;code = 121
char = ;code = 32
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char = 3;code = 51
char = 4;code = 52
char = .;code = 46
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char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = 3;code = 51
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char = .;code = 46
char = 9;code = 57
char = %;code = 37
char = ,;code = 44
char = ;code = 32
char = r;code = 114
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char = s;code = 115
char = p;code = 112
char = e;code = 101
char = c;code = 99
char = t;code = 116
char = i;code = 105
char = v;code = 118
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char = l;code = 108
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char = n;code = 110
char = ;code = 32
char = H;code = 72
char = u;code = 117
char = n;code = 110
char = g;code = 103
char = a;code = 97
char = r;code = 114
char = y;code = 121
char = ,;code = 44
char = ;code = 32
char = a;code = 97
char = l;code = 108
char = c;code = 99
char = o;code = 111
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char = o;code = 111
char = l;code = 108
char = ;code = 32
char = p;code = 112
char = r;code = 114
char = e;code = 101
char = d;code = 100
char = o;code = 111
char = m;code = 109
char = i;code = 105
char = n;code = 110
char = a;code = 97
char = t;code = 116
char = e;code = 101
char = s;code = 115
char = ;code = 32
char = o;code = 111
char = v;code = 118
char = e;code = 101
char = r;code = 114
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char = c;code = 99
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char = o;code = 111
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char = e;code = 101
char = l;code = 108
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = i;code = 105
char = a;code = 97
char = s;code = 115
char = i;code = 105
char = s;code = 115
char = ;code = 32
char = (;code = 40
char = 6;code = 54
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char = 7;code = 55
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char = v;code = 118
char = s;code = 115
char = .;code = 46
char = ;code = 32
char = 2;code = 50
char = 4;code = 52
char = .;code = 46
char = 0;code = 48
char = %;code = 37
char = );code = 41
char = ;;code = 59
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = F;code = 70
char = r;code = 114
char = a;code = 97
char = n;code = 110
char = c;code = 99
char = e;code = 101
char = ,;code = 44
char = ;code = 32
char = a;code = 97
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char = s;code = 115
char = m;code = 109
char = a;code = 97
char = l;code = 108
char = l;code = 108
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char = p;code = 112
char = r;code = 114
char = e;code = 101
char = d;code = 100
char = o;code = 111
char = m;code = 109
char = i;code = 105
char = n;code = 110
char = a;code = 97
char = n;code = 110
char = c;code = 99
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char = f;code = 102
char = ;code = 32
char = a;code = 97
char = l;code = 108
char = c;code = 99
char = o;code = 111
char = h;code = 104
char = o;code = 111
char = l;code = 108
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char = w;code = 119
char = a;code = 97
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char = ;code = 32
char = s;code = 115
char = e;code = 101
char = e;code = 101
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char = (;code = 40
char = 3;code = 51
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char = .;code = 46
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char = s;code = 115
char = .;code = 46
char = ;code = 32
char = 2;code = 50
char = 4;code = 52
char = .;code = 46
char = 6;code = 54
char = %;code = 37
char = );code = 41
char = ;;code = 59
char = ;code = 32
char = a;code = 97
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char = e;code = 101
char = c;code = 99
char = e;code = 101
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char = t;code = 116
char = a;code = 97
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char = r;code = 114
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char = s;code = 115
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char = ;code = 32
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char = .;code = 46
char = 2;code = 50
char = %;code = 37
char = ,;code = 44
char = ;code = 32
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char = s;code = 115
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char = v;code = 118
char = e;code = 101
char = l;code = 108
char = y;code = 121
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char = .;code = 46
char = ;code = 32
char = T;code = 84
char = h;code = 104
char = e;code = 101
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char = d;code = 100
char = i;code = 105
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char = f;code = 102
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char = e;code = 101
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char = n;code = 110
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char = t;code = 116
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char = e;code = 101
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char = f;code = 102
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char = e;code = 101
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char = a;code = 97
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char = o;code = 111
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char = e;code = 101
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char = G;code = 71
char = r;code = 114
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char = e;code = 101
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char = e;code = 101
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char = d;code = 100
char = ;code = 32
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char = t;code = 116
char = a;code = 97
char = l;code = 108
char = y;code = 121
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char = t;code = 116
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char = t;code = 116
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char = c;code = 99
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char = s;code = 115
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char = T;code = 84
char = h;code = 104
char = e;code = 101
char = r;code = 114
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char = i;code = 105
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char = u;code = 117
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char = a;code = 97
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char = i;code = 105
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char = a;code = 97
char = s;code = 115
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char = o;code = 111
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char = <;code = 60
char = b;code = 98
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char = l;code = 108
char = o;code = 111
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char = p;code = 112
char = r;code = 114
char = e;code = 101
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char = o;code = 111
char = m;code = 109
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char = t;code = 116
char = e;code = 101
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char = n;code = 110
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char = e;code = 101
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char = t;code = 116
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char = ;code = 32
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char = r;code = 114
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char = i;code = 105
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char = g;code = 103
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char = ;code = 32
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char = e;code = 101
char = c;code = 99
char = r;code = 114
char = o;code = 111
char = t;code = 116
char = i;code = 105
char = c;code = 99
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char = n;code = 110
char = c;code = 99
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char = ;code = 32
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char = t;code = 116
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char = c;code = 99
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char = g;code = 103
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char = o;code = 111
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char = s;code = 115
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char = ;code = 32
char = a;code = 97
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char = ;code = 32
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char = e;code = 101
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char = h;code = 104
char = i;code = 105
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char = w;code = 119
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char = o;code = 111
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char = l;code = 108
char = i;code = 105
char = t;code = 116
char = y;code = 121
char = ;code = 32
char = a;code = 97
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result sql = INTRODUCTION : In recent years, many advances have been made in the diagnosis and treatment of acute pancreatitis that have lead to a significant reduction in both morbidity and mortality; however, knowledge of the etiology and of the relation between etiology and mortality is far from complete.

AIM : To obtain a more comprehensive view of the etiology and mortality of acute pancreatitis in Europe than has been given by previous single-center studies.

METHODOLOGY : The study comprised 1,068 patients in five European countries who were admitted to hospitals for acute pancreatitis from January 1990 to December 1994. Data for each patient were collected on a standardized form.

RESULTS : Of the 1,068 patients (692 men, 376 women; mean age, 52.8 years; range, 10-95 years), 589 had edematous pancreatitis, and 479 the necrotic form. Cholelithiasis (37.1%) and alcohol (41.0%) were the most frequent etiologic factors. In Germany, cholelithiasis and alcohol occurred with similar frequency (34.9 and 37.9%, respectively); in Hungary, alcohol predominates over cholelithiasis (60.7 vs. 24.0%); in France, a small predominance of alcohol was seen (38.5 vs. 24.6%); and in Greece and Italy, there was a clear predominance of cholelithiasis over alcohol (71.4 vs. 6.0% and 60.3 vs. 13.2%, respectively). The differences in the frequency of cholelithiasis and alcohol between Greece and Italy and the other countries were statistically significant (p < 0.01). Eighty-three patients (7.8%) died of acute pancreatitis; 77 (16.1%) had necrotic disease and 6 (1.0%) edematous. There was no statistically significant difference in mortality among the etiologic groups, and no relation was found between mortality and age.

CONCLUSION : Both cholelithiasis and alcohol were main etiologic factors in the more northern countries studied, whereas cholelithiasis alone predominated in the more southern ones. Mortality was high for necrotic pancreatitis; it was similar among the various etiologic groups, and there was no relationship between mortality and age.

Publication: Pancreas 2002 Apr ;24(3)::223-7.
Publication Date: 2002 Apr
Study Author(s): Gullo, Lucio;Migliori, Marina;Oláh, Attila;Farkas, Gyula;Levy, Philippe;Arvanitakis, Constantine;Lankisch, Paul;Beger, Hans;
Institution: Department of Internal Medicine and Gastroenterology, University of Bologna, Bologna, Italy. [email protected]
Shortcut link to this study:
INTRODUCTION : In recent years, many advances have been made in the diagnosis and treatment of acute pancreatitis that have lead to a significant reduction in both morbidity and mortality; however, knowledge of the etiology and of the relation between etiology and mortality is far from complete.

AIM : To obtain a more comprehensive view of the etiology and mortality of acute pancreatitis in Europe than has been given by previous single-center studies.

METHODOLOGY : The study comprised 1,068 patients in five European countries who were admitted to hospitals for acute pancreatitis from January 1990 to December 1994. Data for each patient were collected on a standardized form.

RESULTS : Of the 1,068 patients (692 men, 376 women; mean age, 52.8 years; range, 10-95 years), 589 had edematous pancreatitis, and 479 the necrotic form. Cholelithiasis (37.1%) and alcohol (41.0%) were the most frequent etiologic factors. In Germany, cholelithiasis and alcohol occurred with similar frequency (34.9 and 37.9%, respectively); in Hungary, alcohol predominates over cholelithiasis (60.7 vs. 24.0%); in France, a small predominance of alcohol was seen (38.5 vs. 24.6%); and in Greece and Italy, there was a clear predominance of cholelithiasis over alcohol (71.4 vs. 6.0% and 60.3 vs. 13.2%, respectively). The differences in the frequency of cholelithiasis and alcohol between Greece and Italy and the other countries were statistically significant (p < 0.01). Eighty-three patients (7.8%) died of acute pancreatitis; 77 (16.1%) had necrotic disease and 6 (1.0%) edematous. There was no statistically significant difference in mortality among the etiologic groups, and no relation was found between mortality and age.

CONCLUSION : Both cholelithiasis and alcohol were main etiologic factors in the more northern countries studied, whereas cholelithiasis alone predominated in the more southern ones. Mortality was high for necrotic pancreatitis; it was similar among the various etiologic groups, and there was no relationship between mortality and age.
PMID: 11893928

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