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char = r;code = 114
char = v;code = 118
char = e;code = 101
char = r;code = 114
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char = b;code = 98
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char = i;code = 105
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char = t;code = 116
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char = f;code = 102
char = ;code = 32
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char = ;code = 32
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char = e;code = 101
char = r;code = 114
char = m;code = 109
char = e;code = 101
char = t;code = 116
char = h;code = 104
char = r;code = 114
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = c;code = 99
char = r;code = 114
char = e;code = 101
char = m;code = 109
char = e;code = 101
char = ;code = 32
char = r;code = 114
char = i;code = 105
char = n;code = 110
char = s;code = 115
char = e;code = 101
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = o;code = 111
char = u;code = 117
char = t;code = 116
char = ;code = 32
char = a;code = 97
char = d;code = 100
char = j;code = 106
char = u;code = 117
char = n;code = 110
char = c;code = 99
char = t;code = 116
char = i;code = 105
char = v;code = 118
char = e;code = 101
char = ;code = 32
char = c;code = 99
char = o;code = 111
char = m;code = 109
char = b;code = 98
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char = n;code = 110
char = g;code = 103
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char = i;code = 105
char = n;code = 110
char = ;code = 32
char = p;code = 112
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = s;code = 115
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = h;code = 104
char = e;code = 101
char = a;code = 97
char = d;code = 100
char = ;code = 32
char = l;code = 108
char = i;code = 105
char = c;code = 99
char = e;code = 101
char = .;code = 46
result sql = An observer-blinded study of 1% permethrin creme rinse with and without adjunctive combing in patients with head lice.
An observer-blinded study of 1% permethrin creme rinse with and without adjunctive combing in patients with head lice.
char = <;code = 60
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char = O;code = 79
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char = C;code = 67
char = T;code = 84
char = I;code = 73
char = V;code = 86
char = E;code = 69
char = S;code = 83
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
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char = e;code = 101
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char = m;code = 109
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char = e;code = 101
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char = f;code = 102
char = ;code = 32
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char = I;code = 73
char = X;code = 88
char = ;code = 32
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char = n;code = 110
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char = r;code = 114
char = ;code = 32
char = L;code = 76
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char = m;code = 109
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char = H;code = 72
char = e;code = 101
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char = c;code = 99
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char = e;code = 101
char = ,;code = 44
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char = M;code = 77
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char = r;code = 114
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char = ;code = 32
char = P;code = 80
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char = ,;code = 44
char = ;code = 32
char = N;code = 78
char = J;code = 74
char = );code = 41
char = ;code = 32
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char = %;code = 37
char = ;code = 32
char = P;code = 80
char = e;code = 101
char = r;code = 114
char = m;code = 109
char = e;code = 101
char = t;code = 116
char = h;code = 104
char = r;code = 114
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = C;code = 67
char = r;code = 114
char = e;code = 101
char = m;code = 109
char = e;code = 101
char = ;code = 32
char = R;code = 82
char = i;code = 105
char = n;code = 110
char = s;code = 115
char = e;code = 101
char = ;code = 32
char = L;code = 76
char = i;code = 105
char = c;code = 99
char = e;code = 101
char = ;code = 32
char = T;code = 84
char = r;code = 114
char = e;code = 101
char = a;code = 97
char = t;code = 116
char = m;code = 109
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = ;code = 32
char = (;code = 40
char = 1;code = 49
char = %;code = 37
char = ;code = 32
char = P;code = 80
char = L;code = 76
char = T;code = 84
char = );code = 41
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = o;code = 111
char = u;code = 117
char = t;code = 116
char = ;code = 32
char = c;code = 99
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char = m;code = 109
char = b;code = 98
char = i;code = 105
char = n;code = 110
char = g;code = 103
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = l;code = 108
char = l;code = 108
char = ;code = 32
char = e;code = 101
char = f;code = 102
char = f;code = 102
char = e;code = 101
char = c;code = 99
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char = i;code = 105
char = v;code = 118
char = e;code = 101
char = l;code = 108
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char = t;code = 116
char = r;code = 114
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char = a;code = 97
char = t;code = 116
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char = /;code = 47
char = =;code = 61
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char = 5;code = 53
char = %;code = 37
char = ;code = 32
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char = f;code = 102
char = ;code = 32
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char = a;code = 97
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char = i;code = 105
char = e;code = 101
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char = s;code = 115
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char = ;code = 32
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char = ;code = 32
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char = ;code = 32
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = d;code = 100
char = a;code = 97
char = y;code = 121
char = ;code = 32
char = 1;code = 49
char = 5;code = 53
char = ;;code = 59
char = ;code = 32
char = t;code = 116
char = o;code = 111
char = ;code = 32
char = d;code = 100
char = e;code = 101
char = t;code = 116
char = e;code = 101
char = r;code = 114
char = m;code = 109
char = i;code = 105
char = n;code = 110
char = e;code = 101
char = ;code = 32
char = w;code = 119
char = h;code = 104
char = e;code = 101
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = c;code = 99
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char = m;code = 109
char = b;code = 98
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char = n;code = 110
char = g;code = 103
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char = i;code = 105
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char = f;code = 102
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char = e;code = 101
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char = f;code = 102
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char = c;code = 99
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char = c;code = 99
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char = .;code = 46
char = <;code = 60
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char = r;code = 114
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char = >;code = 62
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = S;code = 83
char = T;code = 84
char = U;code = 85
char = D;code = 68
char = Y;code = 89
char = ;code = 32
char = D;code = 68
char = E;code = 69
char = S;code = 83
char = I;code = 73
char = G;code = 71
char = N;code = 78
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
char = b;code = 98
char = >;code = 62
char = A;code = 65
char = ;code = 32
char = r;code = 114
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char = d;code = 100
char = o;code = 111
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char = z;code = 122
char = e;code = 101
char = d;code = 100
char = ,;code = 44
char = ;code = 32
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char = e;code = 101
char = r;code = 114
char = v;code = 118
char = e;code = 101
char = r;code = 114
char = -;code = 45
char = b;code = 98
char = l;code = 108
char = i;code = 105
char = n;code = 110
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char = e;code = 101
char = d;code = 100
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char = d;code = 100
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char = e;code = 101
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char = l;code = 108
char = e;code = 101
char = d;code = 100
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char = 9;code = 57
char = 5;code = 53
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char = i;code = 105
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char = f;code = 102
char = e;code = 101
char = s;code = 115
char = t;code = 116
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = a;code = 97
char = d;code = 100
char = u;code = 117
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char = t;code = 116
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char = a;code = 97
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char = ;code = 32
char = c;code = 99
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char = i;code = 105
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char = ;code = 32
char = A;code = 65
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char = l;code = 108
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char = i;code = 105
char = e;code = 101
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char = t;code = 116
char = s;code = 115
char = ;code = 32
char = w;code = 119
char = e;code = 101
char = r;code = 114
char = e;code = 101
char = ;code = 32
char = t;code = 116
char = r;code = 114
char = e;code = 101
char = a;code = 97
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char = e;code = 101
char = d;code = 100
char = ;code = 32
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char = t;code = 116
char = h;code = 104
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char = 1;code = 49
char = %;code = 37
char = ;code = 32
char = P;code = 80
char = L;code = 76
char = T;code = 84
char = ;code = 32
char = o;code = 111
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char = ;code = 32
char = d;code = 100
char = a;code = 97
char = y;code = 121
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char = 1;code = 49
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char = a;code = 97
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char = d;code = 100
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char = f;code = 102
char = ;code = 32
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char = l;code = 108
char = l;code = 108
char = ;code = 32
char = i;code = 105
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char = d;code = 100
char = a;code = 97
char = y;code = 121
char = ;code = 32
char = 8;code = 56
char = .;code = 46
char = ;code = 32
char = O;code = 79
char = n;code = 110
char = e;code = 101
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = i;code = 105
char = r;code = 114
char = d;code = 100
char = ;code = 32
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char = f;code = 102
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char = h;code = 104
char = o;code = 111
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char = e;code = 101
char = h;code = 104
char = o;code = 111
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char = d;code = 100
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char = ;code = 32
char = w;code = 119
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char = e;code = 101
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char = r;code = 114
char = a;code = 97
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char = o;code = 111
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char = i;code = 105
char = z;code = 122
char = e;code = 101
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char = ;code = 32
char = t;code = 116
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char = e;code = 101
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char = c;code = 99
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char = b;code = 98
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char = g;code = 103
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char = h;code = 104
char = e;code = 101
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char = g;code = 103
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char = f;code = 102
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char = s;code = 115
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char = s;code = 115
char = e;code = 101
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char = ;code = 32
char = b;code = 98
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char = ;code = 32
char = (;code = 40
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char = o;code = 111
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char = (;code = 40
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char = i;code = 105
char = n;code = 110
char = g;code = 103
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char = ;code = 32
char = d;code = 100
char = a;code = 97
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char = ,;code = 44
char = ;code = 32
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char = d;code = 100
char = ;code = 32
char = 1;code = 49
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char = ;code = 32
char = T;code = 84
char = h;code = 104
char = e;code = 101
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char = f;code = 102
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char = c;code = 99
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char = w;code = 119
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char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
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char = <;code = 60
char = b;code = 98
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char = R;code = 82
char = E;code = 69
char = S;code = 83
char = U;code = 85
char = L;code = 76
char = T;code = 84
char = S;code = 83
char = ;code = 32
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char = ;code = 32
char = <;code = 60
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char = b;code = 98
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char = I;code = 73
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char = t;code = 116
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char = e;code = 101
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char = n;code = 110
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char = b;code = 98
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char = p;code = 112
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char = t;code = 116
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char = e;code = 101
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char = l;code = 108
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char = c;code = 99
char = e;code = 101
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char = f;code = 102
char = r;code = 114
char = e;code = 101
char = e;code = 101
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char = r;code = 114
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char = t;code = 116
char = e;code = 101
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char = w;code = 119
char = a;code = 97
char = s;code = 115
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char = 8;code = 56
char = 3;code = 51
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char = %;code = 37
char = ;code = 32
char = o;code = 111
char = n;code = 110
char = ;code = 32
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char = /;code = 47
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char = n;code = 110
char = ;code = 32
char = t;code = 116
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char = s;code = 115
char = ;code = 32
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char = o;code = 111
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char = t;code = 116
char = i;code = 105
char = o;code = 111
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char = 1;code = 49
char = %;code = 37
char = ;code = 32
char = P;code = 80
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char = a;code = 97
char = s;code = 115
char = ;code = 32
char = s;code = 115
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char = n;code = 110
char = i;code = 105
char = f;code = 102
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char = a;code = 97
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char = s;code = 115
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char = n;code = 110
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char = 5;code = 53
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char = ;code = 32
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char = f;code = 102
char = e;code = 101
char = c;code = 99
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char = e;code = 101
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
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char = g;code = 103
char = g;code = 103
char = e;code = 101
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char = s;code = 115
char = ;code = 32
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char = s;code = 115
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char = n;code = 110
char = c;code = 99
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char = o;code = 111
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char = ;code = 32
char = P;code = 80
char = L;code = 76
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char = ;code = 32
char = T;code = 84
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char = f;code = 102
char = a;code = 97
char = i;code = 105
char = l;code = 108
char = u;code = 117
char = r;code = 114
char = e;code = 101
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char = ;code = 32
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char = ;code = 32
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char = r;code = 114
char = a;code = 97
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char = e;code = 101
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char = l;code = 108
char = i;code = 105
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char = y;code = 121
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char = ;code = 32
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char = n;code = 110
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char = n;code = 110
char = c;code = 99
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char = i;code = 105
char = v;code = 118
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char = e;code = 101
char = a;code = 97
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char = m;code = 109
char = e;code = 101
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char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = i;code = 105
char = s;code = 115
char = ;code = 32
char = s;code = 115
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char = .;code = 46
result sql = OBJECTIVES : To determine if NIX (Warner Lambert Healthcare, Morris Plains, NJ) 1% Permethrin Creme Rinse Lice Treatment (1% PLT) without combing will effectively treat >/=95% of patients on day 2 or on day 15; to determine whether combing influences efficacy.

STUDY DESIGN : A randomized, observer-blinded study enrolled 95 infested adults and children. All patients were treated with 1% PLT on day 1 and, if still infested, on day 8. One third of households were randomized to the combing group and two thirds to the no-combing group. Efficacy was assessed by: (1) visual inspection on days 1, 2, 8, 9, and 15 and, (2) shampooing/straining on days 2, 9, and 15. The target efficacy was 95%.

RESULTS : In the no-combing group, the lice-free rate was 83.1% on day 2 (95% CI, 71.0-91.6), 45.8% on day 8 (before second treatment) (95% CI, 32.7-59.2), 77.6% on day 9 (95% CI, 64.7-87.5), and 78.3% on day 15 (95% CI, 65.8-87.9). Adjunctive combing did not improve efficacy on any day.

CONCLUSIONS : In this population, 1% PLT was significantly less than 95% effective and suggests resistance to 1% PLT. The failure of nit removal combing by nonprofessional caregivers to improve efficacy demonstrates the unreliability of combing as adjunctive treatment in this setting.

Publication: J. Pediatr. 2002 Nov ;141(5)::665-70.
Publication Date: 2002 Nov
Study Author(s): Meinking, Terri L;Clineschmidt, Coleen M;Chen, Cong;Kolber, Michael A;Tipping, Robert W;Furtek, Christine I;Villar, Maria Elena;Guzzo, Cynthia A;
Institution: Department of Dermatology, University of Miami School of Medicine, Florida 33101, USA.
Shortcut link to this study:
OBJECTIVES : To determine if NIX (Warner Lambert Healthcare, Morris Plains, NJ) 1% Permethrin Creme Rinse Lice Treatment (1% PLT) without combing will effectively treat >/=95% of patients on day 2 or on day 15; to determine whether combing influences efficacy.

STUDY DESIGN : A randomized, observer-blinded study enrolled 95 infested adults and children. All patients were treated with 1% PLT on day 1 and, if still infested, on day 8. One third of households were randomized to the combing group and two thirds to the no-combing group. Efficacy was assessed by: (1) visual inspection on days 1, 2, 8, 9, and 15 and, (2) shampooing/straining on days 2, 9, and 15. The target efficacy was 95%.

RESULTS : In the no-combing group, the lice-free rate was 83.1% on day 2 (95% CI, 71.0-91.6), 45.8% on day 8 (before second treatment) (95% CI, 32.7-59.2), 77.6% on day 9 (95% CI, 64.7-87.5), and 78.3% on day 15 (95% CI, 65.8-87.9). Adjunctive combing did not improve efficacy on any day.

CONCLUSIONS : In this population, 1% PLT was significantly less than 95% effective and suggests resistance to 1% PLT. The failure of nit removal combing by nonprofessional caregivers to improve efficacy demonstrates the unreliability of combing as adjunctive treatment in this setting.
PMID: 12410195

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