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result sql = Synthesis of potential anti-HIV GP120 inhibitors using a lysine template.
Synthesis of potential anti-HIV GP120 inhibitors using a lysine template.
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char = d;code = 100
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char = w;code = 119
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result sql = Various acylated proteins have been reported in the literature to possess anti-HIV activity. Described here is the preparation of lysine monomers, dimers and trimers acylated with various anhydrides and dioxalanones as simplified mimics of the acylated proteins. Compounds were assayed against HIV-infected C8166 cells and some showed weak anti-HIV activity.

Publication: J Enzyme Inhib Med Chem 2002 Jun ;17(3)::175-82.
Publication Date: 2002 Jun
Study Author(s): Doyl, Valerie E;Klimkait, Thomas;Mahmood, Naheed;Slater, Martin;Hazen, Richard J;Gilbert, Ian H;
Institution:
Shortcut link to this study:

Various acylated proteins have been reported in the literature to possess anti-HIV activity. Described here is the preparation of lysine monomers, dimers and trimers acylated with various anhydrides and dioxalanones as simplified mimics of the acylated proteins. Compounds were assayed against HIV-infected C8166 cells and some showed weak anti-HIV activity.

PMID: 12443043

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