|
|
char = H;code = 72
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char = n;code = 110
char = g;code = 103
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char = c;code = 99
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char = ;code = 32
char = c;code = 99
char = h;code = 104
char = e;code = 101
char = m;code = 109
char = o;code = 111
char = p;code = 112
char = r;code = 114
char = e;code = 101
char = v;code = 118
char = e;code = 101
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char = k;code = 107
char = e;code = 101
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char = B;code = 66
char = .;code = 46
char = ;code = 32
char = F;code = 70
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char = c;code = 99
char = t;code = 116
char = u;code = 117
char = r;code = 114
char = e;code = 101
char = .;code = 46
result sql = Human lung cancer chemoprevention strategies: Parker B. Francis lecture.
Human lung cancer chemoprevention strategies: Parker B. Francis lecture.char = P;code = 80
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char = r;code = 114
char = m;code = 109
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char = l;code = 108
char = o;code = 111
char = g;code = 103
char = i;code = 105
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char = r;code = 114
char = ;code = 32
char = n;code = 110
char = u;code = 117
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char = l;code = 108
char = ;code = 32
char = p;code = 112
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char = v;code = 118
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char = e;code = 101
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char = l;code = 108
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char = o;code = 111
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char = e;code = 101
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char = i;code = 105
char = f;code = 102
char = i;code = 105
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = m;code = 109
char = u;code = 117
char = l;code = 108
char = t;code = 116
char = i;code = 105
char = p;code = 112
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char = e;code = 101
char = ;code = 32
char = a;code = 97
char = d;code = 100
char = v;code = 118
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char = s;code = 115
char = e;code = 101
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char = m;code = 109
char = o;code = 111
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char = e;code = 101
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char = u;code = 117
char = l;code = 108
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char = f;code = 102
char = f;code = 102
char = e;code = 101
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char = .;code = 46
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char = N;code = 78
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char = e;code = 101
char = r;code = 114
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char = h;code = 104
char = e;code = 101
char = l;code = 108
char = e;code = 101
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char = s;code = 115
char = ,;code = 44
char = ;code = 32
char = c;code = 99
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char = e;code = 101
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char = m;code = 109
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char = a;code = 97
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char = a;code = 97
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char = t;code = 116
char = i;code = 105
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char = p;code = 112
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char = o;code = 111
char = m;code = 109
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char = d;code = 100
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char = m;code = 109
char = a;code = 97
char = n;code = 110
char = y;code = 121
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char = a;code = 97
char = l;code = 108
char = r;code = 114
char = e;code = 101
char = a;code = 97
char = d;code = 100
char = y;code = 121
char = ;code = 32
char = a;code = 97
char = p;code = 112
char = p;code = 112
char = r;code = 114
char = o;code = 111
char = v;code = 118
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = a;code = 97
char = s;code = 115
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = r;code = 114
char = a;code = 97
char = p;code = 112
char = i;code = 105
char = e;code = 101
char = s;code = 115
char = .;code = 46
char = ;code = 32
char = T;code = 84
char = h;code = 104
char = e;code = 101
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char = m;code = 109
char = o;code = 111
char = s;code = 115
char = t;code = 116
char = ;code = 32
char = a;code = 97
char = c;code = 99
char = t;code = 116
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char = e;code = 101
char = a;code = 97
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char = r;code = 114
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char = n;code = 110
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char = l;code = 108
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char = i;code = 105
char = s;code = 115
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char = u;code = 117
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char = e;code = 101
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char = n;code = 110
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char = i;code = 105
char = b;code = 98
char = i;code = 105
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char = i;code = 105
char = o;code = 111
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char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = a;code = 97
char = r;code = 114
char = a;code = 97
char = c;code = 99
char = h;code = 104
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char = d;code = 100
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char = h;code = 104
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char = >;code = 62
result sql = Pharmacologic or nutritional prevention of lung cancers is needed, especially for 60 million Americans who are former smokers. A portfolio of large-scale trials of beta-carotene, beta-carotene with and without vitamin E, and beta-carotene plus vitamin A demonstrated no benefit whatsoever from beta-carotene. The alpha-Tocopherol/beta-Carotene Trial and the beta-Carotene and Retinol Efficacy Trial found significant increases in lung cancer risk and total mortality. Laboratory research soon identified multiple adverse molecular effects. Nevertheless, chemoprevention remains an active, promising strategy, with new hypotheses and new candidate agents, including many already approved as therapies. The most active area currently is focused on selective inhibition of arachidonic metabolism, both Cox-2 and Lox pathways.
char = u;code = 117
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char = k;code = 107
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char = B;code = 66
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char = c;code = 99
char = t;code = 116
char = u;code = 117
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char = e;code = 101
char = .;code = 46
result sql = Human lung cancer chemoprevention strategies: Parker B. Francis lecture.
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char = /;code = 47
char = >;code = 62
result sql = Pharmacologic or nutritional prevention of lung cancers is needed, especially for 60 million Americans who are former smokers. A portfolio of large-scale trials of beta-carotene, beta-carotene with and without vitamin E, and beta-carotene plus vitamin A demonstrated no benefit whatsoever from beta-carotene. The alpha-Tocopherol/beta-Carotene Trial and the beta-Carotene and Retinol Efficacy Trial found significant increases in lung cancer risk and total mortality. Laboratory research soon identified multiple adverse molecular effects. Nevertheless, chemoprevention remains an active, promising strategy, with new hypotheses and new candidate agents, including many already approved as therapies. The most active area currently is focused on selective inhibition of arachidonic metabolism, both Cox-2 and Lox pathways.
Publication: Chest 2004 May ;125(5 Suppl)::123S-7S.
Publication Date: 2004 May
Study Author(s): Omenn, Gilbert S;
Institution: University of Michigan, Ann Arbor, MI 48109-0656, USA. [email protected]
Shortcut link to this study:
Publication Date: 2004 May
Study Author(s): Omenn, Gilbert S;
Institution: University of Michigan, Ann Arbor, MI 48109-0656, USA. [email protected]
Shortcut link to this study:
Pharmacologic or nutritional prevention of lung cancers is needed, especially for 60 million Americans who are former smokers. A portfolio of large-scale trials of beta-carotene, beta-carotene with and without vitamin E, and beta-carotene plus vitamin A demonstrated no benefit whatsoever from beta-carotene. The alpha-Tocopherol/beta-Carotene Trial and the beta-Carotene and Retinol Efficacy Trial found significant increases in lung cancer risk and total mortality. Laboratory research soon identified multiple adverse molecular effects. Nevertheless, chemoprevention remains an active, promising strategy, with new hypotheses and new candidate agents, including many already approved as therapies. The most active area currently is focused on selective inhibition of arachidonic metabolism, both Cox-2 and Lox pathways.
PMID: 15136459
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