|
|
char = [;code = 91
char = E;code = 69
char = f;code = 102
char = f;code = 102
char = e;code = 101
char = c;code = 99
char = t;code = 116
char = s;code = 115
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = g;code = 103
char = e;code = 101
char = n;code = 110
char = i;code = 105
char = s;code = 115
char = t;code = 116
char = e;code = 101
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = N;code = 78
char = O;code = 79
char = S;code = 83
char = ,;code = 44
char = ;code = 32
char = G;code = 71
char = S;code = 83
char = H;code = 72
char = -;code = 45
char = P;code = 80
char = x;code = 120
char = ;code = 32
char = a;code = 97
char = c;code = 99
char = t;code = 116
char = i;code = 105
char = v;code = 118
char = i;code = 105
char = t;code = 116
char = i;code = 105
char = e;code = 101
char = s;code = 115
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = N;code = 78
char = O;code = 79
char = ,;code = 44
char = ;code = 32
char = G;code = 71
char = S;code = 83
char = H;code = 72
char = ,;code = 44
char = ;code = 32
char = M;code = 77
char = D;code = 68
char = A;code = 65
char = ;code = 32
char = c;code = 99
char = o;code = 111
char = n;code = 110
char = t;code = 116
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = s;code = 115
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = M;code = 77
char = C;code = 67
char = F;code = 70
char = ;code = 32
char = h;code = 104
char = u;code = 117
char = m;code = 109
char = a;code = 97
char = n;code = 110
char = ;code = 32
char = b;code = 98
char = r;code = 114
char = e;code = 101
char = a;code = 97
char = s;code = 115
char = t;code = 116
char = ;code = 32
char = c;code = 99
char = a;code = 97
char = n;code = 110
char = c;code = 99
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = c;code = 99
char = e;code = 101
char = l;code = 108
char = l;code = 108
char = s;code = 115
char = ];code = 93
char = .;code = 46
result sql = [Effects of genistein on NOS, GSH-Px activities and NO, GSH, MDA contents in MCF human breast cancer cells].
[Effects of genistein on NOS, GSH-Px activities and NO, GSH, MDA contents in MCF human breast cancer cells].char = <;code = 60
char = b;code = 98
char = >;code = 62
char = O;code = 79
char = B;code = 66
char = J;code = 74
char = E;code = 69
char = C;code = 67
char = T;code = 84
char = I;code = 73
char = V;code = 86
char = E;code = 69
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
char = b;code = 98
char = >;code = 62
char = T;code = 84
char = o;code = 111
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = v;code = 118
char = e;code = 101
char = s;code = 115
char = t;code = 116
char = i;code = 105
char = g;code = 103
char = a;code = 97
char = t;code = 116
char = e;code = 101
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = m;code = 109
char = e;code = 101
char = c;code = 99
char = h;code = 104
char = a;code = 97
char = n;code = 110
char = i;code = 105
char = s;code = 115
char = m;code = 109
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = a;code = 97
char = t;code = 116
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = g;code = 103
char = e;code = 101
char = n;code = 110
char = i;code = 105
char = s;code = 115
char = t;code = 116
char = e;code = 101
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = h;code = 104
char = i;code = 105
char = b;code = 98
char = i;code = 105
char = t;code = 116
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = M;code = 77
char = C;code = 67
char = F;code = 70
char = ;code = 32
char = h;code = 104
char = u;code = 117
char = m;code = 109
char = a;code = 97
char = n;code = 110
char = ;code = 32
char = b;code = 98
char = r;code = 114
char = e;code = 101
char = a;code = 97
char = s;code = 115
char = t;code = 116
char = ;code = 32
char = c;code = 99
char = a;code = 97
char = n;code = 110
char = c;code = 99
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = c;code = 99
char = e;code = 101
char = l;code = 108
char = l;code = 108
char = .;code = 46
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = M;code = 77
char = E;code = 69
char = T;code = 84
char = H;code = 72
char = O;code = 79
char = D;code = 68
char = S;code = 83
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
char = b;code = 98
char = >;code = 62
char = T;code = 84
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = a;code = 97
char = c;code = 99
char = t;code = 116
char = i;code = 105
char = v;code = 118
char = i;code = 105
char = t;code = 116
char = i;code = 105
char = e;code = 101
char = s;code = 115
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = g;code = 103
char = l;code = 108
char = u;code = 117
char = t;code = 116
char = a;code = 97
char = t;code = 116
char = h;code = 104
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = e;code = 101
char = ;code = 32
char = p;code = 112
char = e;code = 101
char = r;code = 114
char = o;code = 111
char = x;code = 120
char = i;code = 105
char = d;code = 100
char = a;code = 97
char = s;code = 115
char = e;code = 101
char = ;code = 32
char = (;code = 40
char = G;code = 71
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char = H;code = 72
char = -;code = 45
char = P;code = 80
char = x;code = 120
char = );code = 41
char = ,;code = 44
char = ;code = 32
char = n;code = 110
char = i;code = 105
char = t;code = 116
char = r;code = 114
char = i;code = 105
char = c;code = 99
char = ;code = 32
char = o;code = 111
char = x;code = 120
char = i;code = 105
char = d;code = 100
char = e;code = 101
char = ;code = 32
char = s;code = 115
char = y;code = 121
char = n;code = 110
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = t;code = 116
char = a;code = 97
char = s;code = 115
char = e;code = 101
char = ;code = 32
char = (;code = 40
char = N;code = 78
char = O;code = 79
char = S;code = 83
char = );code = 41
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = c;code = 99
char = o;code = 111
char = n;code = 110
char = t;code = 116
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = s;code = 115
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = n;code = 110
char = i;code = 105
char = t;code = 116
char = r;code = 114
char = i;code = 105
char = c;code = 99
char = ;code = 32
char = o;code = 111
char = x;code = 120
char = i;code = 105
char = d;code = 100
char = e;code = 101
char = ;code = 32
char = (;code = 40
char = N;code = 78
char = O;code = 79
char = );code = 41
char = ,;code = 44
char = ;code = 32
char = g;code = 103
char = l;code = 108
char = u;code = 117
char = t;code = 116
char = a;code = 97
char = t;code = 116
char = h;code = 104
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = e;code = 101
char = ;code = 32
char = (;code = 40
char = G;code = 71
char = S;code = 83
char = H;code = 72
char = );code = 41
char = ,;code = 44
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char = m;code = 109
char = a;code = 97
char = l;code = 108
char = o;code = 111
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char = d;code = 100
char = i;code = 105
char = a;code = 97
char = l;code = 108
char = d;code = 100
char = e;code = 101
char = h;code = 104
char = y;code = 121
char = d;code = 100
char = e;code = 101
char = ;code = 32
char = (;code = 40
char = M;code = 77
char = D;code = 68
char = A;code = 65
char = );code = 41
char = ;code = 32
char = b;code = 98
char = o;code = 111
char = t;code = 116
char = h;code = 104
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char = i;code = 105
char = n;code = 110
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char = c;code = 99
char = u;code = 117
char = l;code = 108
char = t;code = 116
char = u;code = 117
char = r;code = 114
char = e;code = 101
char = ;code = 32
char = s;code = 115
char = u;code = 117
char = p;code = 112
char = e;code = 101
char = r;code = 114
char = n;code = 110
char = a;code = 97
char = t;code = 116
char = a;code = 97
char = n;code = 110
char = t;code = 116
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = c;code = 99
char = e;code = 101
char = l;code = 108
char = l;code = 108
char = s;code = 115
char = ;code = 32
char = w;code = 119
char = e;code = 101
char = r;code = 114
char = e;code = 101
char = ;code = 32
char = e;code = 101
char = x;code = 120
char = a;code = 97
char = m;code = 109
char = i;code = 105
char = n;code = 110
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = b;code = 98
char = y;code = 121
char = ;code = 32
char = e;code = 101
char = n;code = 110
char = z;code = 122
char = y;code = 121
char = m;code = 109
char = e;code = 101
char = ;code = 32
char = m;code = 109
char = e;code = 101
char = t;code = 116
char = h;code = 104
char = o;code = 111
char = d;code = 100
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = s;code = 115
char = p;code = 112
char = e;code = 101
char = c;code = 99
char = t;code = 116
char = r;code = 114
char = o;code = 111
char = p;code = 112
char = h;code = 104
char = o;code = 111
char = t;code = 116
char = o;code = 111
char = m;code = 109
char = e;code = 101
char = t;code = 116
char = r;code = 114
char = y;code = 121
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = s;code = 115
char = p;code = 112
char = e;code = 101
char = c;code = 99
char = t;code = 116
char = i;code = 105
char = v;code = 118
char = e;code = 101
char = l;code = 108
char = y;code = 121
char = .;code = 46
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = R;code = 82
char = E;code = 69
char = S;code = 83
char = U;code = 85
char = L;code = 76
char = T;code = 84
char = S;code = 83
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
char = b;code = 98
char = >;code = 62
char = W;code = 87
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = g;code = 103
char = e;code = 101
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char = i;code = 105
char = s;code = 115
char = t;code = 116
char = e;code = 101
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char = n;code = 110
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char = i;code = 105
char = n;code = 110
char = c;code = 99
char = r;code = 114
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char = a;code = 97
char = s;code = 115
char = i;code = 105
char = n;code = 110
char = g;code = 103
char = ,;code = 44
char = ;code = 32
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char = h;code = 104
char = e;code = 101
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char = a;code = 97
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char = i;code = 105
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char = i;code = 105
char = t;code = 116
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char = f;code = 102
char = ;code = 32
char = G;code = 71
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char = -;code = 45
char = P;code = 80
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char = O;code = 79
char = S;code = 83
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char = ;code = 32
char = c;code = 99
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char = e;code = 101
char = n;code = 110
char = t;code = 116
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = N;code = 78
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char = (;code = 40
char = P;code = 80
char = ;code = 32
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char = b;code = 98
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char = e;code = 101
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char = (;code = 40
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char = <;code = 60
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char = <;code = 60
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char = c;code = 99
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char = a;code = 97
char = f;code = 102
char = f;code = 102
char = e;code = 101
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char = N;code = 78
char = O;code = 79
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char = b;code = 98
char = r;code = 114
char = e;code = 101
char = a;code = 97
char = s;code = 115
char = t;code = 116
char = ;code = 32
char = c;code = 99
char = a;code = 97
char = n;code = 110
char = c;code = 99
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = c;code = 99
char = e;code = 101
char = l;code = 108
char = l;code = 108
char = s;code = 115
char = ;code = 32
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char = o;code = 111
char = w;code = 119
char = t;code = 116
char = h;code = 104
char = .;code = 46
result sql = OBJECTIVE : To investigate the mechanism that the genistein inhibit the MCF human breast cancer cell.
METHODS : The activities of glutathione peroxidase (GSH-Px), nitric oxide synthetase (NOS) and the contents of nitric oxide (NO), glutathione (GSH), malondialdehyde (MDA) both in culture supernatant and cells were examined by enzyme method and spectrophotometry respectively.
RESULTS : With genistein increasing, the activities of GSH-Px, NOS and the contents of NO increased significantly (P < 0.05), while the contents of GSH, MDA decreased both in culture supernatant and cells (P < 0.05).
CONCLUSION : Genistein can affect NO synthesis and antioxidation in MCF breast cancer cells. It may be one of the mechanisms that the genistein inhibit the MCF breast cancer cells growth.
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char = f;code = 102
char = f;code = 102
char = e;code = 101
char = c;code = 99
char = t;code = 116
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = g;code = 103
char = e;code = 101
char = n;code = 110
char = i;code = 105
char = s;code = 115
char = t;code = 116
char = e;code = 101
char = i;code = 105
char = n;code = 110
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char = o;code = 111
char = n;code = 110
char = ;code = 32
char = N;code = 78
char = O;code = 79
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char = ,;code = 44
char = ;code = 32
char = G;code = 71
char = S;code = 83
char = H;code = 72
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char = x;code = 120
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char = a;code = 97
char = c;code = 99
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char = i;code = 105
char = v;code = 118
char = i;code = 105
char = t;code = 116
char = i;code = 105
char = e;code = 101
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char = d;code = 100
char = ;code = 32
char = N;code = 78
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char = G;code = 71
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char = e;code = 101
char = n;code = 110
char = t;code = 116
char = s;code = 115
char = ;code = 32
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char = M;code = 77
char = C;code = 67
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char = ;code = 32
char = h;code = 104
char = u;code = 117
char = m;code = 109
char = a;code = 97
char = n;code = 110
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char = b;code = 98
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char = e;code = 101
char = a;code = 97
char = s;code = 115
char = t;code = 116
char = ;code = 32
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char = a;code = 97
char = n;code = 110
char = c;code = 99
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = c;code = 99
char = e;code = 101
char = l;code = 108
char = l;code = 108
char = s;code = 115
char = ];code = 93
char = .;code = 46
result sql = [Effects of genistein on NOS, GSH-Px activities and NO, GSH, MDA contents in MCF human breast cancer cells].
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char = m;code = 109
char = e;code = 101
char = c;code = 99
char = h;code = 104
char = a;code = 97
char = n;code = 110
char = i;code = 105
char = s;code = 115
char = m;code = 109
char = s;code = 115
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = a;code = 97
char = t;code = 116
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = g;code = 103
char = e;code = 101
char = n;code = 110
char = i;code = 105
char = s;code = 115
char = t;code = 116
char = e;code = 101
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = h;code = 104
char = i;code = 105
char = b;code = 98
char = i;code = 105
char = t;code = 116
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = M;code = 77
char = C;code = 67
char = F;code = 70
char = ;code = 32
char = b;code = 98
char = r;code = 114
char = e;code = 101
char = a;code = 97
char = s;code = 115
char = t;code = 116
char = ;code = 32
char = c;code = 99
char = a;code = 97
char = n;code = 110
char = c;code = 99
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = c;code = 99
char = e;code = 101
char = l;code = 108
char = l;code = 108
char = s;code = 115
char = ;code = 32
char = g;code = 103
char = r;code = 114
char = o;code = 111
char = w;code = 119
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char = .;code = 46
result sql = OBJECTIVE : To investigate the mechanism that the genistein inhibit the MCF human breast cancer cell.
METHODS : The activities of glutathione peroxidase (GSH-Px), nitric oxide synthetase (NOS) and the contents of nitric oxide (NO), glutathione (GSH), malondialdehyde (MDA) both in culture supernatant and cells were examined by enzyme method and spectrophotometry respectively.
RESULTS : With genistein increasing, the activities of GSH-Px, NOS and the contents of NO increased significantly (P < 0.05), while the contents of GSH, MDA decreased both in culture supernatant and cells (P < 0.05).
CONCLUSION : Genistein can affect NO synthesis and antioxidation in MCF breast cancer cells. It may be one of the mechanisms that the genistein inhibit the MCF breast cancer cells growth.
Publication: Wei Sheng Yan Jiu 2004 Jul ;33(4)::468-9.
Publication Date: 2004 Jul
Study Author(s): Sun, Shu'ai;Zhao, Xiulan;Zhao, Li;
Institution: School of Public Health, Shandong University, Ji'nan 250012, China.
Shortcut link to this study:
Publication Date: 2004 Jul
Study Author(s): Sun, Shu'ai;Zhao, Xiulan;Zhao, Li;
Institution: School of Public Health, Shandong University, Ji'nan 250012, China.
Shortcut link to this study:
OBJECTIVE : To investigate the mechanism that the genistein inhibit the MCF human breast cancer cell.
METHODS : The activities of glutathione peroxidase (GSH-Px), nitric oxide synthetase (NOS) and the contents of nitric oxide (NO), glutathione (GSH), malondialdehyde (MDA) both in culture supernatant and cells were examined by enzyme method and spectrophotometry respectively.
RESULTS : With genistein increasing, the activities of GSH-Px, NOS and the contents of NO increased significantly (P < 0.05), while the contents of GSH, MDA decreased both in culture supernatant and cells (P < 0.05).
CONCLUSION : Genistein can affect NO synthesis and antioxidation in MCF breast cancer cells. It may be one of the mechanisms that the genistein inhibit the MCF breast cancer cells growth.
METHODS : The activities of glutathione peroxidase (GSH-Px), nitric oxide synthetase (NOS) and the contents of nitric oxide (NO), glutathione (GSH), malondialdehyde (MDA) both in culture supernatant and cells were examined by enzyme method and spectrophotometry respectively.
RESULTS : With genistein increasing, the activities of GSH-Px, NOS and the contents of NO increased significantly (P < 0.05), while the contents of GSH, MDA decreased both in culture supernatant and cells (P < 0.05).
CONCLUSION : Genistein can affect NO synthesis and antioxidation in MCF breast cancer cells. It may be one of the mechanisms that the genistein inhibit the MCF breast cancer cells growth.
PMID: 15461279
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