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char = S;code = 83
char = t;code = 116
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char = d;code = 100
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char = .;code = 46
result sql = Heme iron, zinc and upper digestive tract cancer: the Iowa Women's Health Study.
Heme iron, zinc and upper digestive tract cancer: the Iowa Women's Health Study.
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char = ;code = 32
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char = o;code = 111
char = f;code = 102
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char = u;code = 117
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char = g;code = 103
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char = t;code = 116
char = i;code = 105
char = v;code = 118
char = e;code = 101
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char = c;code = 99
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char = e;code = 101
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char = 5;code = 53
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char = s;code = 115
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char = e;code = 101
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char = e;code = 101
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char = ;code = 32
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char = y;code = 121
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char = i;code = 105
char = t;code = 116
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char = ;code = 32
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char = o;code = 111
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char = a;code = 97
char = c;code = 99
char = e;code = 101
char = m;code = 109
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char = e;code = 101
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char = a;code = 97
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char = y;code = 121
char = ,;code = 44
char = ;code = 32
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char = l;code = 108
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char = v;code = 118
char = i;code = 105
char = t;code = 116
char = a;code = 97
char = m;code = 109
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = t;code = 116
char = a;code = 97
char = k;code = 107
char = e;code = 101
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = t;code = 116
char = a;code = 97
char = k;code = 107
char = e;code = 101
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = s;code = 115
char = a;code = 97
char = t;code = 116
char = u;code = 117
char = r;code = 114
char = a;code = 97
char = t;code = 116
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = f;code = 102
char = a;code = 97
char = t;code = 116
char = ,;code = 44
char = ;code = 32
char = v;code = 118
char = i;code = 105
char = t;code = 116
char = a;code = 97
char = m;code = 109
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = C;code = 67
char = ,;code = 44
char = ;code = 32
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char = i;code = 105
char = t;code = 116
char = a;code = 97
char = m;code = 109
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = E;code = 69
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = f;code = 102
char = o;code = 111
char = l;code = 108
char = a;code = 97
char = t;code = 116
char = e;code = 101
char = ;code = 32
char = d;code = 100
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char = d;code = 100
char = ;code = 32
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char = o;code = 111
char = t;code = 116
char = ;code = 32
char = c;code = 99
char = h;code = 104
char = a;code = 97
char = n;code = 110
char = g;code = 103
char = e;code = 101
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = r;code = 114
char = e;code = 101
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char = u;code = 117
char = l;code = 108
char = t;code = 116
char = s;code = 115
char = .;code = 46
char = ;code = 32
char = H;code = 72
char = i;code = 105
char = g;code = 103
char = h;code = 104
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = t;code = 116
char = a;code = 97
char = k;code = 107
char = e;code = 101
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = h;code = 104
char = e;code = 101
char = m;code = 109
char = e;code = 101
char = ;code = 32
char = i;code = 105
char = r;code = 114
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = i;code = 105
char = s;code = 115
char = ;code = 32
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char = s;code = 115
char = s;code = 115
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char = a;code = 97
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char = e;code = 101
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char = w;code = 119
char = i;code = 105
char = t;code = 116
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char = ;code = 32
char = h;code = 104
char = i;code = 105
char = g;code = 103
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char = s;code = 115
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char = i;code = 105
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char = r;code = 114
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char = n;code = 110
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char = o;code = 111
char = f;code = 102
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char = z;code = 122
char = i;code = 105
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char = c;code = 99
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char = i;code = 105
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char = ;code = 32
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char = o;code = 111
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char = e;code = 101
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char = i;code = 105
char = t;code = 116
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char = ;code = 32
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char = w;code = 119
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char = ;code = 32
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char = s;code = 115
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char = ;code = 32
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char = e;code = 101
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char = c;code = 99
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char = ;code = 32
char = c;code = 99
char = a;code = 97
char = n;code = 110
char = c;code = 99
char = e;code = 101
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result sql = We examined associations among dietary heme iron as a possible pro-oxidant, dietary zinc as a possible antioxidant, and the incidence of upper digestive tract cancer; 34,708 postmenopausal women, aged 55-69 years at baseline who completed a food frequency questionnaire, were followed 16 years. There were 75 upper digestive tract cancer cases (52 gastric cancer and 23 esophageal cancer). When heme iron and zinc were mutually adjusted, in dose-response manners, heme iron intake was positively associated with the risk of upper digestive tract cancer, while zinc intake was inversely associated with risk. After adjusting for age, total energy intake, cigarette smoking and alcohol consumption, relative risks for quintiles of heme iron intake were 1.0, 1.53, 2.15, 3.05 and 2.83 (p for trend = 0.06) and corresponding relative risks for zinc intake were 1.0, 0.86, 0.42, 0.37 and 0.13 (p for trend < 0.01). Additional adjustment for body mass index, physical activity, hormone replacement therapy, multivitamin intake and intake of saturated fat, vitamin C, vitamin E and folate did not change the results. Higher intake of heme iron is associated with higher risk, while higher intake of zinc is associated with lower, risk of upper digestive tract cancer.

Publication: Int. J. Cancer 2005 Nov 20 ;117(4)::643-7.
Publication Date: 2005 Nov 20
Study Author(s): Lee, Duk-Hee;Anderson, Kristin E;Folsom, Aaron R;Jacobs, David R;
Institution: Department of Preventive Medicine, College of Medicine, Kyungpook National University, Daegu, Korea.
Shortcut link to this study:
We examined associations among dietary heme iron as a possible pro-oxidant, dietary zinc as a possible antioxidant, and the incidence of upper digestive tract cancer; 34,708 postmenopausal women, aged 55-69 years at baseline who completed a food frequency questionnaire, were followed 16 years. There were 75 upper digestive tract cancer cases (52 gastric cancer and 23 esophageal cancer). When heme iron and zinc were mutually adjusted, in dose-response manners, heme iron intake was positively associated with the risk of upper digestive tract cancer, while zinc intake was inversely associated with risk. After adjusting for age, total energy intake, cigarette smoking and alcohol consumption, relative risks for quintiles of heme iron intake were 1.0, 1.53, 2.15, 3.05 and 2.83 (p for trend = 0.06) and corresponding relative risks for zinc intake were 1.0, 0.86, 0.42, 0.37 and 0.13 (p for trend < 0.01). Additional adjustment for body mass index, physical activity, hormone replacement therapy, multivitamin intake and intake of saturated fat, vitamin C, vitamin E and folate did not change the results. Higher intake of heme iron is associated with higher risk, while higher intake of zinc is associated with lower, risk of upper digestive tract cancer.
PMID: 15929082

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