char = D;code = 68 char = i;code = 105 char = a;code = 97 char = g;code = 103 char = n;code = 110 char = o;code = 111 char = s;code = 115 char = t;code = 116 char = i;code = 105 char = c;code = 99 char = ;code = 32 char = v;code = 118 char = a;code = 97 char = l;code = 108 char = u;code = 117 char = e;code = 101 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = H;code = 72 char = S;code = 83 char = P;code = 80 char = 7;code = 55 char = 0;code = 48 char = ,;code = 44 char = ;code = 32 char = g;code = 103 char = l;code = 108 char = y;code = 121 char = p;code = 112 char = i;code = 105 char = c;code = 99 char = a;code = 97 char = n;code = 110 char = ;code = 32 char = 3;code = 51 char = ,;code = 44 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = g;code = 103 char = l;code = 108 char = u;code = 117 char = t;code = 116 char = a;code = 97 char = m;code = 109 char = i;code = 105 char = n;code = 110 char = e;code = 101 char = ;code = 32 char = s;code = 115 char = y;code = 121 char = n;code = 110 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = t;code = 116 char = a;code = 97 char = s;code = 115 char = e;code = 101 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = h;code = 104 char = e;code = 101 char = p;code = 112 char = a;code = 97 char = t;code = 116 char = o;code = 111 char = c;code = 99 char = e;code = 101 char = l;code = 108 char = l;code = 108 char = u;code = 117 char = l;code = 108 char = a;code = 97 char = r;code = 114 char = ;code = 32 char = n;code = 110 char = o;code = 111 char = d;code = 100 char = u;code = 117 char = l;code = 108 char = e;code = 101 char = s;code = 115 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = c;code = 99 char = i;code = 105 char = r;code = 114 char = r;code = 114 char = h;code = 104 char = o;code = 111 char = s;code = 115 char = i;code = 105 char = s;code = 115 char = .;code = 46 result sql = Diagnostic value of HSP70, glypican 3, and glutamine synthetase in hepatocellular nodules in cirrhosis.
Diagnostic value of HSP70, glypican 3, and glutamine synthetase in hepatocellular nodules in cirrhosis.char = <;code = 60 char = b;code = 98 char = >;code = 62 char = U;code = 85 char = N;code = 78 char = L;code = 76 char = A;code = 65 char = B;code = 66 char = E;code = 69 char = L;code = 76 char = L;code = 76 char = E;code = 69 char = D;code = 68 char = ;code = 32 char = :;code = 58 char = ;code = 32 char = <;code = 60 char = /;code = 47 char = b;code = 98 char = >;code = 62 char = H;code = 72 char = e;code = 101 char = p;code = 112 char = a;code = 97 char = t;code = 116 char = o;code = 111 char = c;code = 99 char = e;code = 101 char = l;code = 108 char = l;code = 108 char = u;code = 117 char = l;code = 108 char = a;code = 97 char = r;code = 114 char = ;code = 32 char = n;code = 110 char = o;code = 111 char = d;code = 100 char = u;code = 117 char = l;code = 108 char = e;code = 101 char = s;code = 115 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = c;code = 99 char = i;code = 105 char = r;code = 114 char = r;code = 114 char = h;code = 104 char = o;code = 111 char = s;code = 115 char = i;code = 105 char = s;code = 115 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = c;code = 99 char = l;code = 108 char = u;code = 117 char = d;code = 100 char = e;code = 101 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = g;code = 103 char = e;code = 101 char = n;code = 110 char = e;code = 101 char = r;code = 114 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = e;code = 101 char = ;code = 32 char = (;code = 40 char = l;code = 108 char = a;code = 97 char = r;code = 114 char = g;code = 103 char = e;code = 101 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = g;code = 103 char = e;code = 101 char = n;code = 110 char = e;code = 101 char = r;code = 114 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = e;code = 101 char = ,;code = 44 char = ;code = 32 char = L;code = 76 char = R;code = 82 char = N;code = 78 char = );code = 41 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = d;code = 100 char = y;code = 121 char = s;code = 115 char = p;code = 112 char = l;code = 108 char = a;code = 97 char = s;code = 115 char = t;code = 116 char = i;code = 105 char = c;code = 99 char = ;code = 32 char = (;code = 40 char = l;code = 108 char = o;code = 111 char = w;code = 119 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = h;code = 104 char = i;code = 105 char = g;code = 103 char = h;code = 104 char = ;code = 32 char = g;code = 103 char = r;code = 114 char = a;code = 97 char = d;code = 100 char = e;code = 101 char = ,;code = 44 char = ;code = 32 char = L;code = 76 char = G;code = 71 char = D;code = 68 char = N;code = 78 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = H;code = 72 char = G;code = 71 char = D;code = 68 char = N;code = 78 char = );code = 41 char = ;code = 32 char = n;code = 110 char = o;code = 111 char = d;code = 100 char = u;code = 117 char = l;code = 108 char = e;code = 101 char = s;code = 115 char = ,;code = 44 char = ;code = 32 char = e;code = 101 char = a;code = 97 char = r;code = 114 char = l;code = 108 char = y;code = 121 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = g;code = 103 char = r;code = 114 char = a;code = 97 char = d;code = 100 char = e;code = 101 char = ;code = 32 char = 1;code = 49 char = ;code = 32 char = H;code = 72 char = C;code = 67 char = C;code = 67 char = ;code = 32 char = (;code = 40 char = e;code = 101 char = H;code = 72 char = C;code = 67 char = C;code = 67 char = -;code = 45 char = G;code = 71 char = 1;code = 49 char = );code = 41 char = ,;code = 44 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = o;code = 111 char = v;code = 118 char = e;code = 101 char = r;code = 114 char = t;code = 116 char = ;code = 32 char = H;code = 72 char = C;code = 67 char = C;code = 67 char = .;code = 46 char = ;code = 32 char = T;code = 84 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = d;code = 100 char = i;code = 105 char = f;code = 102 char = f;code = 102 char = e;code = 101 char = r;code = 114 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = i;code = 105 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = d;code = 100 char = i;code = 105 char = a;code = 97 char = g;code = 103 char = n;code = 110 char = o;code = 111 char = s;code = 115 char = i;code = 105 char = s;code = 115 char = ;code = 32 char = m;code = 109 char = a;code = 97 char = y;code = 121 char = ;code = 32 char = b;code = 98 char = e;code = 101 char = ;code = 32 char = p;code = 112 char = a;code = 97 char = r;code = 114 char = t;code = 116 char = i;code = 105 char = c;code = 99 char = u;code = 117 char = l;code = 108 char = a;code = 97 char = r;code = 114 char = l;code = 108 char = y;code = 121 char = ;code = 32 char = d;code = 100 char = i;code = 105 char = f;code = 102 char = f;code = 102 char = i;code = 105 char = c;code = 99 char = u;code = 117 char = l;code = 108 char = t;code = 116 char = ;code = 32 char = w;code = 119 char = h;code = 104 char = e;code = 101 char = n;code = 110 char = ;code = 32 char = l;code = 108 char = e;code = 101 char = s;code = 115 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = c;code = 99 char = h;code = 104 char = ;code = 32 char = a;code = 97 char = s;code = 115 char = ;code = 32 char = H;code = 72 char = G;code = 71 char = D;code = 68 char = N;code = 78 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = e;code = 101 char = H;code = 72 char = C;code = 67 char = C;code = 67 char = -;code = 45 char = G;code = 71 char = 1;code = 49 char = ;code = 32 char = a;code = 97 char = r;code = 114 char = e;code = 101 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = v;code = 118 char = o;code = 111 char = l;code = 108 char = v;code = 118 char = e;code = 101 char = d;code = 100 char = .;code = 46 char = ;code = 32 char = W;code = 87 char = e;code = 101 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = v;code = 118 char = e;code = 101 char = s;code = 115 char = t;code = 116 char = i;code = 105 char = g;code = 103 char = a;code = 97 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = d;code = 100 char = i;code = 105 char = a;code = 97 char = g;code = 103 char = n;code = 110 char = o;code = 111 char = s;code = 115 char = t;code = 116 char = i;code = 105 char = c;code = 99 char = ;code = 32 char = y;code = 121 char = i;code = 105 char = e;code = 101 char = l;code = 108 char = d;code = 100 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = a;code = 97 char = ;code = 32 char = p;code = 112 char = a;code = 97 char = n;code = 110 char = e;code = 101 char = l;code = 108 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = 3;code = 51 char = ;code = 32 char = p;code = 112 char = u;code = 117 char = t;code = 116 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = e;code = 101 char = ;code = 32 char = m;code = 109 char = a;code = 97 char = r;code = 114 char = k;code = 107 char = e;code = 101 char = r;code = 114 char = s;code = 115 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = h;code = 104 char = e;code = 101 char = p;code = 112 char = a;code = 97 char = t;code = 116 char = o;code = 111 char = c;code = 99 char = e;code = 101 char = l;code = 108 char = l;code = 108 char = u;code = 117 char = l;code = 108 char = a;code = 97 char = r;code = 114 char = ;code = 32 char = m;code = 109 char = a;code = 97 char = l;code = 108 char = i;code = 105 char = g;code = 103 char = n;code = 110 char = a;code = 97 char = n;code = 110 char = c;code = 99 char = y;code = 121 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = c;code = 99 char = h;code = 104 char = ;code = 32 char = a;code = 97 char = s;code = 115 char = ;code = 32 char = H;code = 72 char = S;code = 83 char = P;code = 80 char = 7;code = 55 char = 0;code = 48 char = ,;code = 44 char = ;code = 32 char = g;code = 103 char = l;code = 108 char = y;code = 121 char = p;code = 112 char = i;code = 105 char = c;code = 99 char = a;code = 97 char = n;code = 110 char = ;code = 32 char = 3;code = 51 char = ;code = 32 char = (;code = 40 char = G;code = 71 char = P;code = 80 char = C;code = 67 char = 3;code = 51 char = );code = 41 char = ,;code = 44 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = g;code = 103 char = l;code = 108 char = u;code = 117 char = t;code = 116 char = a;code = 97 char = m;code = 109 char = i;code = 105 char = n;code = 110 char = e;code = 101 char = ;code = 32 char = s;code = 115 char = y;code = 121 char = n;code = 110 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = t;code = 116 char = a;code = 97 char = s;code = 115 char = e;code = 101 char = ;code = 32 char = (;code = 40 char = G;code = 71 char = S;code = 83 char = );code = 41 char = .;code = 46 char = ;code = 32 char = W;code = 87 char = e;code = 101 char = ;code = 32 char = s;code = 115 char = e;code = 101 char = l;code = 108 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = 5;code = 53 char = 2;code = 50 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = r;code = 114 char = g;code = 103 char = i;code = 105 char = c;code = 99 char = a;code = 97 char = l;code = 108 char = l;code = 108 char = y;code = 121 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = m;code = 109 char = o;code = 111 char = v;code = 118 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = n;code = 110 char = o;code = 111 char = n;code = 110 char = m;code = 109 char = a;code = 97 char = l;code = 108 char = i;code = 105 char = g;code = 103 char = n;code = 110 char = a;code = 97 char = n;code = 110 char = t;code = 116 char = ;code = 32 char = n;code = 110 char = o;code = 111 char = d;code = 100 char = u;code = 117 char = l;code = 108 char = e;code = 101 char = s;code = 115 char = ;code = 32 char = (;code = 40 char = 1;code = 49 char = 5;code = 53 char = ;code = 32 char = L;code = 76 char = R;code = 82 char = N;code = 78 char = s;code = 115 char = ,;code = 44 char = ;code = 32 char = 1;code = 49 char = 5;code = 53 char = ;code = 32 char = L;code = 76 char = G;code = 71 char = D;code = 68 char = N;code = 78 char = s;code = 115 char = ,;code = 44 char = ;code = 32 char = 2;code = 50 char = 2;code = 50 char = ;code = 32 char = H;code = 72 char = G;code = 71 char = D;code = 68 char = N;code = 78 char = s;code = 115 char = );code = 41 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = 5;code = 53 char = 3;code = 51 char = ;code = 32 char = H;code = 72 char = C;code = 67 char = C;code = 67 char = s;code = 115 char = ;code = 32 char = (;code = 40 char = 1;code = 49 char = 0;code = 48 char = ;code = 32 char = e;code = 101 char = a;code = 97 char = r;code = 114 char = l;code = 108 char = y;code = 121 char = ,;code = 44 char = ;code = 32 char = 2;code = 50 char = 2;code = 50 char = ;code = 32 char = g;code = 103 char = r;code = 114 char = a;code = 97 char = d;code = 100 char = e;code = 101 char = ;code = 32 char = 1;code = 49 char = ,;code = 44 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = 2;code = 50 char = 1;code = 49 char = ;code = 32 char = g;code = 103 char = r;code = 114 char = a;code = 97 char = d;code = 100 char = e;code = 101 char = ;code = 32 char = 2;code = 50 char = -;code = 45 char = 3;code = 51 char = );code = 41 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = i;code = 105 char = m;code = 109 char = m;code = 109 char = u;code = 117 char = n;code = 110 char = o;code = 111 char = s;code = 115 char = t;code = 116 char = a;code = 97 char = i;code = 105 char = n;code = 110 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = m;code = 109 char = ;code = 32 char = f;code = 102 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = H;code = 72 char = S;code = 83 char = P;code = 80 char = 7;code = 55 char = 0;code = 48 char = ,;code = 44 char = ;code = 32 char = G;code = 71 char = P;code = 80 char = C;code = 67 char = 3;code = 51 char = ,;code = 44 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = G;code = 71 char = S;code = 83 char = .;code = 46 char = ;code = 32 char = T;code = 84 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = s;code = 115 char = e;code = 101 char = n;code = 110 char = s;code = 115 char = i;code = 105 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = i;code = 105 char = t;code = 116 char = y;code = 121 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = s;code = 115 char = p;code = 112 char = e;code = 101 char = c;code = 99 char = i;code = 105 char = f;code = 102 char = i;code = 105 char = c;code = 99 char = i;code = 105 char = t;code = 116 char = y;code = 121 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = d;code = 100 char = i;code = 105 char = v;code = 118 char = i;code = 105 char = d;code = 100 char = u;code = 117 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = m;code = 109 char = a;code = 97 char = r;code = 114 char = k;code = 107 char = e;code = 101 char = r;code = 114 char = s;code = 115 char = ;code = 32 char = f;code = 102 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = d;code = 100 char = e;code = 101 char = t;code = 116 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = e;code = 101 char = H;code = 72 char = C;code = 67 char = C;code = 67 char = -;code = 45 char = G;code = 71 char = 1;code = 49 char = ;code = 32 char = w;code = 119 char = e;code = 101 char = r;code = 114 char = e;code = 101 char = ;code = 32 char = 5;code = 53 char = 9;code = 57 char = %;code = 37 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = 8;code = 56 char = 6;code = 54 char = %;code = 37 char = ;code = 32 char = f;code = 102 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = G;code = 71 char = S;code = 83 char = ,;code = 44 char = ;code = 32 char = 6;code = 54 char = 9;code = 57 char = %;code = 37 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = 9;code = 57 char = 1;code = 49 char = %;code = 37 char = ;code = 32 char = f;code = 102 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = G;code = 71 char = P;code = 80 char = C;code = 67 char = 3;code = 51 char = ,;code = 44 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = 7;code = 55 char = 8;code = 56 char = %;code = 37 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = 9;code = 57 char = 5;code = 53 char = %;code = 37 char = ;code = 32 char = f;code = 102 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = H;code = 72 char = S;code = 83 char = P;code = 80 char = 7;code = 55 char = 0;code = 48 char = .;code = 46 char = ;code = 32 char = W;code = 87 char = e;code = 101 char = ;code = 32 char = i;code = 105 char = d;code = 100 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = i;code = 105 char = f;code = 102 char = i;code = 105 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = 2;code = 50 char = ;code = 32 char = m;code = 109 char = a;code = 97 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = p;code = 112 char = h;code = 104 char = e;code = 101 char = n;code = 110 char = o;code = 111 char = t;code = 116 char = y;code = 121 char = p;code = 112 char = e;code = 101 char = s;code = 115 char = :;code = 58 char = ;code = 32 char = (;code = 40 char = 1;code = 49 char = );code = 41 char = ;code = 32 char = a;code = 97 char = l;code = 108 char = l;code = 108 char = ;code = 32 char = n;code = 110 char = e;code = 101 char = g;code = 103 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = e;code = 101 char = ,;code = 44 char = ;code = 32 char = s;code = 115 char = e;code = 101 char = e;code = 101 char = n;code = 110 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = 1;code = 49 char = 0;code = 48 char = 0;code = 48 char = %;code = 37 char = ;code = 32 char = L;code = 76 char = R;code = 82 char = N;code = 78 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = L;code = 76 char = G;code = 71 char = D;code = 68 char = N;code = 78 char = ,;code = 44 char = ;code = 32 char = 7;code = 55 char = 3;code = 51 char = %;code = 37 char = ;code = 32 char = H;code = 72 char = G;code = 71 char = D;code = 68 char = N;code = 78 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = 3;code = 51 char = %;code = 37 char = ;code = 32 char = e;code = 101 char = H;code = 72 char = C;code = 67 char = C;code = 67 char = -;code = 45 char = G;code = 71 char = 1;code = 49 char = ;;code = 59 char = ;code = 32 char = (;code = 40 char = 2;code = 50 char = );code = 41 char = ;code = 32 char = a;code = 97 char = l;code = 108 char = l;code = 108 char = ;code = 32 char = p;code = 112 char = o;code = 111 char = s;code = 115 char = i;code = 105 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = e;code = 101 char = ,;code = 44 char = ;code = 32 char = a;code = 97 char = ;code = 32 char = f;code = 102 char = e;code = 101 char = a;code = 97 char = t;code = 116 char = u;code = 117 char = r;code = 114 char = e;code = 101 char = ;code = 32 char = d;code = 100 char = e;code = 101 char = t;code = 116 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = l;code = 108 char = e;code = 101 char = s;code = 115 char = s;code = 115 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = a;code = 97 char = n;code = 110 char = ;code = 32 char = h;code = 104 char = a;code = 97 char = l;code = 108 char = f;code = 102 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = e;code = 101 char = H;code = 72 char = C;code = 67 char = C;code = 67 char = -;code = 45 char = G;code = 71 char = 1;code = 49 char = .;code = 46 char = ;code = 32 char = U;code = 85 char = s;code = 115 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = ;code = 32 char = a;code = 97 char = ;code = 32 char = 3;code = 51 char = -;code = 45 char = m;code = 109 char = a;code = 97 char = r;code = 114 char = k;code = 107 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = p;code = 112 char = a;code = 97 char = n;code = 110 char = e;code = 101 char = l;code = 108 char = ,;code = 44 char = ;code = 32 char = w;code = 119 char = h;code = 104 char = e;code = 101 char = n;code = 110 char = ;code = 32 char = a;code = 97 char = t;code = 116 char = ;code = 32 char = l;code = 108 char = e;code = 101 char = a;code = 97 char = s;code = 115 char = t;code = 116 char = ;code = 32 char = 2;code = 50 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = m;code = 109 char = ,;code = 44 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = g;code = 103 char = a;code = 97 char = r;code = 114 char = d;code = 100 char = l;code = 108 char = e;code = 101 char = s;code = 115 char = s;code = 115 char = ;code = 32 char = w;code = 119 char = h;code = 104 char = i;code = 105 char = c;code = 99 char = h;code = 104 char = ,;code = 44 char = ;code = 32 char = w;code = 119 char = e;code = 101 char = r;code = 114 char = e;code = 101 char = ;code = 32 char = p;code = 112 char = o;code = 111 char = s;code = 115 char = i;code = 105 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = e;code = 101 char = ,;code = 44 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = s;code = 115 char = e;code = 101 char = n;code = 110 char = s;code = 115 char = i;code = 105 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = i;code = 105 char = t;code = 116 char = y;code = 121 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = s;code = 115 char = p;code = 112 char = e;code = 101 char = c;code = 99 char = i;code = 105 char = f;code = 102 char = i;code = 105 char = c;code = 99 char = i;code = 105 char = t;code = 116 char = y;code = 121 char = ;code = 32 char = f;code = 102 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = d;code = 100 char = e;code = 101 char = t;code = 116 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = e;code = 101 char = H;code = 72 char = C;code = 67 char = C;code = 67 char = -;code = 45 char = G;code = 71 char = 1;code = 49 char = ;code = 32 char = w;code = 119 char = e;code = 101 char = r;code = 114 char = e;code = 101 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = s;code = 115 char = p;code = 112 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = e;code = 101 char = l;code = 108 char = y;code = 121 char = ;code = 32 char = 7;code = 55 char = 2;code = 50 char = %;code = 37 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = 1;code = 49 char = 0;code = 48 char = 0;code = 48 char = %;code = 37 char = ;;code = 59 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = m;code = 109 char = o;code = 111 char = s;code = 115 char = t;code = 116 char = ;code = 32 char = s;code = 115 char = e;code = 101 char = n;code = 110 char = s;code = 115 char = i;code = 105 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = e;code = 101 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = m;code = 109 char = b;code = 98 char = i;code = 105 char = n;code = 110 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = w;code = 119 char = a;code = 97 char = s;code = 115 char = ;code = 32 char = H;code = 72 char = S;code = 83 char = P;code = 80 char = 7;code = 55 char = 0;code = 48 char = +;code = 43 char = /;code = 47 char = G;code = 71 char = P;code = 80 char = C;code = 67 char = 3;code = 51 char = +;code = 43 char = ;code = 32 char = (;code = 40 char = 5;code = 53 char = 9;code = 57 char = %;code = 37 char = );code = 41 char = ;code = 32 char = w;code = 119 char = h;code = 104 char = e;code = 101 char = n;code = 110 char = ;code = 32 char = a;code = 97 char = ;code = 32 char = 2;code = 50 char = -;code = 45 char = m;code = 109 char = a;code = 97 char = r;code = 114 char = k;code = 107 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = p;code = 112 char = a;code = 97 char = n;code = 110 char = e;code = 101 char = l;code = 108 char = ;code = 32 char = w;code = 119 char = a;code = 97 char = s;code = 115 char = ;code = 32 char = u;code = 117 char = s;code = 115 char = e;code = 101 char = d;code = 100 char = .;code = 46 char = <;code = 60 char = b;code = 98 char = r;code = 114 char = /;code = 47 char = >;code = 62 char = <;code = 60 char = b;code = 98 char = r;code = 114 char = /;code = 47 char = >;code = 62 char = <;code = 60 char = b;code = 98 char = >;code = 62 char = C;code = 67 char = O;code = 79 char = N;code = 78 char = C;code = 67 char = L;code = 76 char = U;code = 85 char = S;code = 83 char = I;code = 73 char = O;code = 79 char = N;code = 78 char = ;code = 32 char = :;code = 58 char = ;code = 32 char = <;code = 60 char = /;code = 47 char = b;code = 98 char = >;code = 62 char = T;code = 84 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = a;code = 97 char = d;code = 100 char = o;code = 111 char = p;code = 112 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = p;code = 112 char = a;code = 97 char = n;code = 110 char = e;code = 101 char = l;code = 108 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = 3;code = 51 char = ;code = 32 char = m;code = 109 char = a;code = 97 char = r;code = 114 char = k;code = 107 char = e;code = 101 char = r;code = 114 char = s;code = 115 char = ;code = 32 char = i;code = 105 char = s;code = 115 char = ;code = 32 char = v;code = 118 char = e;code = 101 char = r;code = 114 char = y;code = 121 char = ;code = 32 char = h;code = 104 char = e;code = 101 char = l;code = 108 char = p;code = 112 char = f;code = 102 char = u;code = 117 char = l;code = 108 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = d;code = 100 char = i;code = 105 char = s;code = 115 char = t;code = 116 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = u;code = 117 char = i;code = 105 char = s;code = 115 char = h;code = 104 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = ;code = 32 char = e;code = 101 char = H;code = 72 char = C;code = 67 char = C;code = 67 char = -;code = 45 char = G;code = 71 char = 1;code = 49 char = ;code = 32 char = f;code = 102 char = r;code = 114 char = o;code = 111 char = m;code = 109 char = ;code = 32 char = d;code = 100 char = y;code = 121 char = s;code = 115 char = p;code = 112 char = l;code = 108 char = a;code = 97 char = s;code = 115 char = t;code = 116 char = i;code = 105 char = c;code = 99 char = ;code = 32 char = n;code = 110 char = o;code = 111 char = d;code = 100 char = u;code = 117 char = l;code = 108 char = e;code = 101 char = s;code = 115 char = ;code = 32 char = a;code = 97 char = r;code = 114 char = i;code = 105 char = s;code = 115 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = c;code = 99 char = i;code = 105 char = r;code = 114 char = r;code = 114 char = h;code = 104 char = o;code = 111 char = s;code = 115 char = i;code = 105 char = s;code = 115 char = .;code = 46 result sql = UNLABELLED : Hepatocellular nodules in cirrhosis include regenerative (large regenerative, LRN) and dysplastic (low and high grade, LGDN and HGDN) nodules, early and grade 1 HCC (eHCC-G1), and overt HCC. The differential diagnosis may be particularly difficult when lesions such as HGDN and eHCC-G1 are involved. We investigated the diagnostic yield of a panel of 3 putative markers of hepatocellular malignancy such as HSP70, glypican 3 (GPC3), and glutamine synthetase (GS). We selected 52 surgically removed nonmalignant nodules (15 LRNs, 15 LGDNs, 22 HGDNs) and 53 HCCs (10 early, 22 grade 1, and 21 grade 2-3) and immunostained them for HSP70, GPC3, and GS. The sensitivity and specificity of the individual markers for the detection of eHCC-G1 were 59% and 86% for GS, 69% and 91% for GPC3, and 78% and 95% for HSP70. We identified 2 main phenotypes: (1) all negative, seen in 100% LRN and LGDN, 73% HGDN and 3% eHCC-G1; (2) all positive, a feature detected in less than half the eHCC-G1. Using a 3-marker panel, when at least 2 of them, regardless which, were positive, the sensitivity and specificity for the detection of eHCC-G1 were respectively 72% and 100%; the most sensitive combination was HSP70+/GPC3+ (59%) when a 2-marker panel was used.CONCLUSION : The adopted panel of 3 markers is very helpful in distinguishing eHCC-G1 from dysplastic nodules arising in cirrhosis.
Publication: Hepatology 2007 Mar ;45(3)::725-34.
Publication Date: 2007 Mar
Study Author(s): Di Tommaso, Luca;Franchi, Giada;Park, Young Nyun;Fiamengo, Barbara;Destro, Annarita;Morenghi, Emanuela;Montorsi, Marco;Torzilli, Guido;Tommasini, Maurizio;Terracciano, Luigi;Tornillo, Luigi;Vecchione, Raffaella;Roncalli, Massimo;
Institution: Department of Pathology, University of Milan School of Medicine and IRCCS Humanitas Clinical Institute, Rozzano, Milan, Italy, and Institute of Pathology, University Hospital Basel, Switzerland.
Shortcut link to this study:
UNLABELLED : Hepatocellular nodules in cirrhosis include regenerative (large regenerative, LRN) and dysplastic (low and high grade, LGDN and HGDN) nodules, early and grade 1 HCC (eHCC-G1), and overt HCC. The differential diagnosis may be particularly difficult when lesions such as HGDN and eHCC-G1 are involved. We investigated the diagnostic yield of a panel of 3 putative markers of hepatocellular malignancy such as HSP70, glypican 3 (GPC3), and glutamine synthetase (GS). We selected 52 surgically removed nonmalignant nodules (15 LRNs, 15 LGDNs, 22 HGDNs) and 53 HCCs (10 early, 22 grade 1, and 21 grade 2-3) and immunostained them for HSP70, GPC3, and GS. The sensitivity and specificity of the individual markers for the detection of eHCC-G1 were 59% and 86% for GS, 69% and 91% for GPC3, and 78% and 95% for HSP70. We identified 2 main phenotypes: (1) all negative, seen in 100% LRN and LGDN, 73% HGDN and 3% eHCC-G1; (2) all positive, a feature detected in less than half the eHCC-G1. Using a 3-marker panel, when at least 2 of them, regardless which, were positive, the sensitivity and specificity for the detection of eHCC-G1 were respectively 72% and 100%; the most sensitive combination was HSP70+/GPC3+ (59%) when a 2-marker panel was used.CONCLUSION : The adopted panel of 3 markers is very helpful in distinguishing eHCC-G1 from dysplastic nodules arising in cirrhosis.
PMID: 17326147