char = A;code = 65
char = ;code = 32
char = t;code = 116
char = h;code = 104
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char = e;code = 101
char = ;code = 32
char = l;code = 108
char = a;code = 97
char = y;code = 121
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = s;code = 115
char = t;code = 116
char = r;code = 114
char = u;code = 117
char = c;code = 99
char = t;code = 116
char = u;code = 117
char = r;code = 114
char = e;code = 101
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char = m;code = 109
char = o;code = 111
char = d;code = 100
char = e;code = 101
char = l;code = 108
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = f;code = 102
char = l;code = 108
char = u;code = 117
char = o;code = 111
char = r;code = 114
char = i;code = 105
char = d;code = 100
char = a;code = 97
char = t;code = 116
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = e;code = 101
char = n;code = 110
char = a;code = 97
char = m;code = 109
char = e;code = 101
char = l;code = 108
char = ;code = 32
char = c;code = 99
char = o;code = 111
char = n;code = 110
char = t;code = 116
char = a;code = 97
char = i;code = 105
char = n;code = 110
char = i;code = 105
char = n;code = 110
char = g;code = 103
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char = C;code = 67
char = a;code = 97
char = F;code = 70
char = 2;code = 50
char = ,;code = 44
char = ;code = 32
char = C;code = 67
char = a;code = 97
char = (;code = 40
char = O;code = 79
char = H;code = 72
char = );code = 41
char = 2;code = 50
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = F;code = 70
char = A;code = 65
char = p;code = 112
char = .;code = 46
result sql = A three layer structure model of fluoridated enamel containing CaF2, Ca(OH)2 and FAp.
A three layer structure model of fluoridated enamel containing CaF2, Ca(OH)2 and FAp.
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = O;code = 79
char = B;code = 66
char = J;code = 74
char = E;code = 69
char = C;code = 67
char = T;code = 84
char = I;code = 73
char = V;code = 86
char = E;code = 69
char = S;code = 83
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
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char = >;code = 62
char = T;code = 84
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = a;code = 97
char = i;code = 105
char = m;code = 109
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = i;code = 105
char = s;code = 115
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char = s;code = 115
char = t;code = 116
char = u;code = 117
char = d;code = 100
char = y;code = 121
char = ;code = 32
char = w;code = 119
char = a;code = 97
char = s;code = 115
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char = t;code = 116
char = o;code = 111
char = ;code = 32
char = d;code = 100
char = e;code = 101
char = v;code = 118
char = e;code = 101
char = l;code = 108
char = o;code = 111
char = p;code = 112
char = ;code = 32
char = a;code = 97
char = ;code = 32
char = m;code = 109
char = o;code = 111
char = l;code = 108
char = e;code = 101
char = c;code = 99
char = u;code = 117
char = l;code = 108
char = a;code = 97
char = r;code = 114
char = -;code = 45
char = b;code = 98
char = a;code = 97
char = s;code = 115
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = s;code = 115
char = t;code = 116
char = r;code = 114
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char = c;code = 99
char = t;code = 116
char = u;code = 117
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char = a;code = 97
char = l;code = 108
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char = m;code = 109
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char = e;code = 101
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char = o;code = 111
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char = ;code = 32
char = h;code = 104
char = u;code = 117
char = m;code = 109
char = a;code = 97
char = n;code = 110
char = ;code = 32
char = t;code = 116
char = e;code = 101
char = e;code = 101
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = a;code = 97
char = f;code = 102
char = t;code = 116
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = f;code = 102
char = l;code = 108
char = u;code = 117
char = o;code = 111
char = r;code = 114
char = i;code = 105
char = d;code = 100
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = a;code = 97
char = ;code = 32
char = c;code = 99
char = o;code = 111
char = m;code = 109
char = m;code = 109
char = o;code = 111
char = n;code = 110
char = l;code = 108
char = y;code = 121
char = ;code = 32
char = u;code = 117
char = s;code = 115
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = a;code = 97
char = m;code = 109
char = i;code = 105
char = n;code = 110
char = e;code = 101
char = ;code = 32
char = f;code = 102
char = l;code = 108
char = u;code = 117
char = o;code = 111
char = r;code = 114
char = i;code = 105
char = d;code = 100
char = e;code = 101
char = ,;code = 44
char = ;code = 32
char = w;code = 119
char = h;code = 104
char = i;code = 105
char = c;code = 99
char = h;code = 104
char = ;code = 32
char = i;code = 105
char = s;code = 115
char = ;code = 32
char = h;code = 104
char = i;code = 105
char = g;code = 103
char = h;code = 104
char = l;code = 108
char = y;code = 121
char = ;code = 32
char = s;code = 115
char = i;code = 105
char = g;code = 103
char = n;code = 110
char = i;code = 105
char = f;code = 102
char = i;code = 105
char = c;code = 99
char = a;code = 97
char = n;code = 110
char = t;code = 116
char = ;code = 32
char = f;code = 102
char = o;code = 111
char = r;code = 114
char = ;code = 32
char = u;code = 117
char = n;code = 110
char = d;code = 100
char = e;code = 101
char = r;code = 114
char = s;code = 115
char = t;code = 116
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = i;code = 105
char = n;code = 110
char = g;code = 103
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char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = e;code = 101
char = f;code = 102
char = f;code = 102
char = e;code = 101
char = c;code = 99
char = t;code = 116
char = i;code = 105
char = v;code = 118
char = e;code = 101
char = n;code = 110
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char = s;code = 115
char = s;code = 115
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = t;code = 116
char = o;code = 111
char = p;code = 112
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char = a;code = 97
char = l;code = 108
char = ;code = 32
char = f;code = 102
char = l;code = 108
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char = o;code = 111
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char = .;code = 46
char = <;code = 60
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char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = M;code = 77
char = E;code = 69
char = T;code = 84
char = H;code = 72
char = O;code = 79
char = D;code = 68
char = S;code = 83
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
char = b;code = 98
char = >;code = 62
char = T;code = 84
char = h;code = 104
char = i;code = 105
char = s;code = 115
char = ;code = 32
char = m;code = 109
char = u;code = 117
char = l;code = 108
char = t;code = 116
char = i;code = 105
char = ;code = 32
char = m;code = 109
char = e;code = 101
char = t;code = 116
char = h;code = 104
char = o;code = 111
char = d;code = 100
char = ;code = 32
char = s;code = 115
char = t;code = 116
char = u;code = 117
char = d;code = 100
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char = u;code = 117
char = s;code = 115
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = X;code = 88
char = P;code = 80
char = S;code = 83
char = ,;code = 44
char = ;code = 32
char = M;code = 77
char = A;code = 65
char = S;code = 83
char = -;code = 45
char = N;code = 78
char = M;code = 77
char = R;code = 82
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = R;code = 82
char = a;code = 97
char = m;code = 109
char = a;code = 97
char = n;code = 110
char = -;code = 45
char = s;code = 115
char = p;code = 112
char = e;code = 101
char = c;code = 99
char = t;code = 116
char = r;code = 114
char = o;code = 111
char = s;code = 115
char = c;code = 99
char = o;code = 111
char = p;code = 112
char = y;code = 121
char = ;code = 32
char = m;code = 109
char = e;code = 101
char = a;code = 97
char = s;code = 115
char = u;code = 117
char = r;code = 114
char = e;code = 101
char = m;code = 109
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = s;code = 115
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char = i;code = 105
char = n;code = 110
char = ;code = 32
char = o;code = 111
char = r;code = 114
char = d;code = 100
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = t;code = 116
char = o;code = 111
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char = a;code = 97
char = n;code = 110
char = a;code = 97
char = l;code = 108
char = y;code = 121
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char = e;code = 101
char = ;code = 32
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char = o;code = 111
char = w;code = 119
char = d;code = 100
char = e;code = 101
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char = e;code = 101
char = d;code = 100
char = ;code = 32
char = s;code = 115
char = y;code = 121
char = n;code = 110
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = t;code = 116
char = i;code = 105
char = c;code = 99
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char = h;code = 104
char = y;code = 121
char = d;code = 100
char = r;code = 114
char = o;code = 111
char = x;code = 120
char = y;code = 121
char = l;code = 108
char = a;code = 97
char = p;code = 112
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = t;code = 116
char = e;code = 101
char = ;code = 32
char = (;code = 40
char = H;code = 72
char = A;code = 65
char = p;code = 112
char = );code = 41
char = ,;code = 44
char = ;code = 32
char = p;code = 112
char = o;code = 111
char = w;code = 119
char = d;code = 100
char = e;code = 101
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char = e;code = 101
char = d;code = 100
char = ;code = 32
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char = u;code = 117
char = m;code = 109
char = a;code = 97
char = n;code = 110
char = ;code = 32
char = e;code = 101
char = n;code = 110
char = a;code = 97
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char = e;code = 101
char = l;code = 108
char = ;code = 32
char = s;code = 115
char = a;code = 97
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char = p;code = 112
char = l;code = 108
char = e;code = 101
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char = d;code = 100
char = ;code = 32
char = h;code = 104
char = u;code = 117
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char = e;code = 101
char = n;code = 110
char = a;code = 97
char = m;code = 109
char = e;code = 101
char = l;code = 108
char = ;code = 32
char = p;code = 112
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char = e;code = 101
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char = e;code = 101
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char = e;code = 101
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char = a;code = 97
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char = f;code = 102
char = l;code = 108
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char = d;code = 100
char = e;code = 101
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char = (;code = 40
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char = <;code = 60
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char = <;code = 60
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char = S;code = 83
char = U;code = 85
char = L;code = 76
char = T;code = 84
char = S;code = 83
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char = :;code = 58
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char = e;code = 101
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char = c;code = 99
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char = c;code = 99
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char = d;code = 100
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char = G;code = 71
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char = I;code = 73
char = F;code = 70
char = I;code = 73
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char = A;code = 65
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char = C;code = 67
char = E;code = 69
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char = a;code = 97
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result sql = OBJECTIVES : The aim of this study was to develop a molecular-based structural model of human teeth after fluoridation with a commonly used amine fluoride, which is highly significant for understanding the effectiveness of topical fluoridation.

METHODS : This multi method study used XPS, MAS-NMR and Raman-spectroscopy measurements in order to analyze powdered synthetic hydroxylapatite (HAp), powdered human enamel samples and human enamel pieces treated with amine fluoride (Elmex) fluid) in vitro.

RESULTS : The results lead to a complete structural characterization of the fluoridation products. A three layer composition of calcium hydroxide, calcium fluoride and an apatite species was identified.

SIGNIFICANCE : The top surface CaF(2) layer acts as a fluoride reservoir and covers a layer of antimicrobial effective Ca(OH)(2). Ca(OH)(2) is a well-known therapeutic agent. However, up to now Ca(OH)(2) has not been described as a reaction product after topical fluoridation. Below the Ca(OH)(2) layer an acid resistant apatite species (FAp) was detected which reached directly into the bulk enamel HAp species. The three layer composition identified helps to understand the influence of fluoride application in the pathogenic mechanisms of tooth decay. Each component in this newly suggested structure model has a specific function, which explains how topical fluoridation of enamel reduces dental caries and influences its pathogenic mechanisms.

Publication: Dent Mater 2007 Dec ;23(12)::1521-8.
Publication Date: 2007 Dec
Study Author(s): Gerth, Hans U V;Dammaschke, Till;Schäfer, Edgar;Züchner, Harald;
Institution: Institute of Physical Chemistry, University of Münster, Germany.
Shortcut link to this study:
OBJECTIVES : The aim of this study was to develop a molecular-based structural model of human teeth after fluoridation with a commonly used amine fluoride, which is highly significant for understanding the effectiveness of topical fluoridation.

METHODS : This multi method study used XPS, MAS-NMR and Raman-spectroscopy measurements in order to analyze powdered synthetic hydroxylapatite (HAp), powdered human enamel samples and human enamel pieces treated with amine fluoride (Elmex) fluid) in vitro.

RESULTS : The results lead to a complete structural characterization of the fluoridation products. A three layer composition of calcium hydroxide, calcium fluoride and an apatite species was identified.

SIGNIFICANCE : The top surface CaF(2) layer acts as a fluoride reservoir and covers a layer of antimicrobial effective Ca(OH)(2). Ca(OH)(2) is a well-known therapeutic agent. However, up to now Ca(OH)(2) has not been described as a reaction product after topical fluoridation. Below the Ca(OH)(2) layer an acid resistant apatite species (FAp) was detected which reached directly into the bulk enamel HAp species. The three layer composition identified helps to understand the influence of fluoride application in the pathogenic mechanisms of tooth decay. Each component in this newly suggested structure model has a specific function, which explains how topical fluoridation of enamel reduces dental caries and influences its pathogenic mechanisms.
PMID: 17353046

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