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result sql = Plasma carotenoids and prostate cancer: a population-based case-control study in Arkansas.
Plasma carotenoids and prostate cancer: a population-based case-control study in Arkansas.
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char = t;code = 116
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char = r;code = 114
char = ;code = 32
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char = h;code = 104
char = e;code = 101
char = r;code = 114
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char = ;code = 32
char = c;code = 99
char = a;code = 97
char = r;code = 114
char = o;code = 111
char = t;code = 116
char = e;code = 101
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char = o;code = 111
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char = d;code = 100
char = s;code = 115
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char = d;code = 100
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char = t;code = 116
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char = l;code = 108
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char = ;code = 32
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char = r;code = 114
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char = a;code = 97
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char = y;code = 121
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char = n;code = 110
char = e;code = 101
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char = h;code = 104
char = i;code = 105
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char = h;code = 104
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char = h;code = 104
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char = e;code = 101
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char = s;code = 115
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char = f;code = 102
char = ;code = 32
char = p;code = 112
char = l;code = 108
char = a;code = 97
char = s;code = 115
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char = a;code = 97
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char = a;code = 97
char = l;code = 108
char = p;code = 112
char = h;code = 104
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char = c;code = 99
char = a;code = 97
char = r;code = 114
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char = t;code = 116
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char = e;code = 101
char = ;code = 32
char = a;code = 97
char = n;code = 110
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char = ;code = 32
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char = e;code = 101
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char = c;code = 99
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char = ;code = 32
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char = a;code = 97
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char = y;code = 121
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char = e;code = 101
char = s;code = 115
char = ;code = 32
char = d;code = 100
char = i;code = 105
char = d;code = 100
char = ;code = 32
char = n;code = 110
char = o;code = 111
char = t;code = 116
char = ;code = 32
char = v;code = 118
char = a;code = 97
char = r;code = 114
char = y;code = 121
char = ;code = 32
char = s;code = 115
char = u;code = 117
char = b;code = 98
char = s;code = 115
char = t;code = 116
char = a;code = 97
char = n;code = 110
char = t;code = 116
char = i;code = 105
char = a;code = 97
char = l;code = 108
char = l;code = 108
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char = ;code = 32
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char = y;code = 121
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char = e;code = 101
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char = c;code = 99
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char = a;code = 97
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char = ;code = 32
char = s;code = 115
char = m;code = 109
char = o;code = 111
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char = i;code = 105
char = n;code = 110
char = g;code = 103
char = ;code = 32
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char = a;code = 97
char = t;code = 116
char = u;code = 117
char = s;code = 115
char = .;code = 46
char = ;code = 32
char = T;code = 84
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char = s;code = 115
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char = s;code = 115
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char = d;code = 100
char = d;code = 100
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = t;code = 116
char = o;code = 111
char = ;code = 32
char = t;code = 116
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char = e;code = 101
char = ;code = 32
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char = m;code = 109
char = e;code = 101
char = r;code = 114
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char = n;code = 110
char = g;code = 103
char = ;code = 32
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char = i;code = 105
char = d;code = 100
char = e;code = 101
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char = a;code = 97
char = t;code = 116
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char = t;code = 116
char = i;code = 105
char = n;code = 110
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char = ;code = 32
char = l;code = 108
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char = v;code = 118
char = e;code = 101
char = l;code = 108
char = s;code = 115
char = ;code = 32
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char = f;code = 102
char = ;code = 32
char = l;code = 108
char = y;code = 121
char = c;code = 99
char = o;code = 111
char = p;code = 112
char = e;code = 101
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char = e;code = 101
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char = ;code = 32
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char = t;code = 116
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char = e;code = 101
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char = i;code = 105
char = n;code = 110
char = ,;code = 44
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = b;code = 98
char = e;code = 101
char = t;code = 116
char = a;code = 97
char = -;code = 45
char = c;code = 99
char = r;code = 114
char = y;code = 121
char = p;code = 112
char = t;code = 116
char = o;code = 111
char = x;code = 120
char = a;code = 97
char = n;code = 110
char = t;code = 116
char = h;code = 104
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = a;code = 97
char = r;code = 114
char = e;code = 101
char = ;code = 32
char = a;code = 97
char = s;code = 115
char = s;code = 115
char = o;code = 111
char = c;code = 99
char = i;code = 105
char = a;code = 97
char = t;code = 116
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = a;code = 97
char = ;code = 32
char = l;code = 108
char = o;code = 111
char = w;code = 119
char = ;code = 32
char = r;code = 114
char = i;code = 105
char = s;code = 115
char = k;code = 107
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = p;code = 112
char = r;code = 114
char = o;code = 111
char = s;code = 115
char = t;code = 116
char = a;code = 97
char = t;code = 116
char = e;code = 101
char = ;code = 32
char = c;code = 99
char = a;code = 97
char = n;code = 110
char = c;code = 99
char = e;code = 101
char = r;code = 114
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result sql = Carotenoids possess antioxidant properties and thus may protect against prostate cancer. Epidemiological studies of dietary carotenoids and this malignancy were inconsistent, partially due to dietary assessment error. In this study, we aimed to investigate the relation between plasma concentrations of carotenoids and the risk of prostate cancer in a population-based case-control study in Arkansas. Cases (n = 193) were men with prostate cancer diagnosed in 3 major hospitals, and controls (n = 197) were matched to cases by age, race, and county of residence. After adjustment for confounders, plasma levels of lycopene, lutein/zeaxanthin, and beta-cryptoxanthin were inversely associated with prostate cancer risk. Subjects in the highest quartile of plasma lycopene (513.7 microg/l) had a 55% lower risk of prostate cancer than those in the lowest quartile (140.5 microg/l; P trend = 0.042). No apparent association was observed for plasma alpha-carotene and beta-carotene. Further adjustment for the other 4 carotenoids did not materially alter the risk estimates for plasma lycopene, lutein/zeaxanthin, and beta-cryptoxanthin but appeared to result in an elevated risk with high levels of plasma alpha-carotene and beta-carotene. The results of all analyses did not vary substantially by age, race, and smoking status. This study added to the emerging evidence that high circulating levels of lycopene, lutein/zeaxanthin, and beta-cryptoxanthin are associated with a low risk of prostate cancer.

Publication: Nutr Cancer 2007 ;59(1)::46-53.
Publication Date: 2007
Study Author(s): Zhang, Jianjun;Dhakal, Ishwori;Stone, Angie;Ning, Baitang;Greene, Graham;Lang, Nicholas P;Kadlubar, Fred F;
Institution: Department of Epidemiology, Fay W Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA. [email protected]
Shortcut link to this study:
Carotenoids possess antioxidant properties and thus may protect against prostate cancer. Epidemiological studies of dietary carotenoids and this malignancy were inconsistent, partially due to dietary assessment error. In this study, we aimed to investigate the relation between plasma concentrations of carotenoids and the risk of prostate cancer in a population-based case-control study in Arkansas. Cases (n = 193) were men with prostate cancer diagnosed in 3 major hospitals, and controls (n = 197) were matched to cases by age, race, and county of residence. After adjustment for confounders, plasma levels of lycopene, lutein/zeaxanthin, and beta-cryptoxanthin were inversely associated with prostate cancer risk. Subjects in the highest quartile of plasma lycopene (513.7 microg/l) had a 55% lower risk of prostate cancer than those in the lowest quartile (140.5 microg/l; P trend = 0.042). No apparent association was observed for plasma alpha-carotene and beta-carotene. Further adjustment for the other 4 carotenoids did not materially alter the risk estimates for plasma lycopene, lutein/zeaxanthin, and beta-cryptoxanthin but appeared to result in an elevated risk with high levels of plasma alpha-carotene and beta-carotene. The results of all analyses did not vary substantially by age, race, and smoking status. This study added to the emerging evidence that high circulating levels of lycopene, lutein/zeaxanthin, and beta-cryptoxanthin are associated with a low risk of prostate cancer.
PMID: 17927501

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