|
|
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result sql = Improvement in eGFR in patients with chronic kidney disease attending a nephrology clinic.
Improvement in eGFR in patients with chronic kidney disease attending a nephrology clinic.char = <;code = 60
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char = e;code = 101
char = d;code = 100
char = ;code = 32
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char = o;code = 111
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char = f;code = 102
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char = v;code = 118
char = e;code = 101
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char = g;code = 103
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char = o;code = 111
char = u;code = 117
char = p;code = 112
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char = 1;code = 49
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char = s;code = 115
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char = g;code = 103
char = n;code = 110
char = i;code = 105
char = f;code = 102
char = i;code = 105
char = c;code = 99
char = a;code = 97
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char = t;code = 116
char = l;code = 108
char = y;code = 121
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char = p;code = 112
char = r;code = 114
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char = g;code = 103
char = r;code = 114
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char = s;code = 115
char = s;code = 115
char = i;code = 105
char = v;code = 118
char = e;code = 101
char = ;code = 32
char = s;code = 115
char = l;code = 108
char = o;code = 111
char = p;code = 112
char = e;code = 101
char = ;code = 32
char = (;code = 40
char = d;code = 100
char = e;code = 101
char = t;code = 116
char = e;code = 101
char = r;code = 114
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char = o;code = 111
char = r;code = 114
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
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char = );code = 41
char = ;code = 32
char = (;code = 40
char = m;code = 109
char = o;code = 111
char = r;code = 114
char = e;code = 101
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char = n;code = 110
char = e;code = 101
char = g;code = 103
char = a;code = 97
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char = i;code = 105
char = v;code = 118
char = e;code = 101
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char = t;code = 116
char = h;code = 104
char = a;code = 97
char = n;code = 110
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char = -;code = 45
char = 5;code = 53
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char = m;code = 109
char = l;code = 108
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char = m;code = 109
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char = a;code = 97
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char = ;;code = 59
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char = 2;code = 50
char = );code = 41
char = ;code = 32
char = m;code = 109
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char = l;code = 108
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char = p;code = 112
char = r;code = 114
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char = g;code = 103
char = r;code = 114
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char = s;code = 115
char = s;code = 115
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char = ;code = 32
char = s;code = 115
char = l;code = 108
char = o;code = 111
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char = e;code = 101
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char = >;code = 62
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char = 5;code = 53
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char = t;code = 116
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char = ;code = 32
char = <;code = 60
char = o;code = 111
char = r;code = 114
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char = -;code = 45
char = 1;code = 49
char = );code = 41
char = ;;code = 59
char = ;code = 32
char = (;code = 40
char = 3;code = 51
char = );code = 41
char = ;code = 32
char = s;code = 115
char = t;code = 116
char = a;code = 97
char = b;code = 98
char = l;code = 108
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char = ;code = 32
char = s;code = 115
char = l;code = 108
char = o;code = 111
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char = e;code = 101
char = ;code = 32
char = (;code = 40
char = >;code = 62
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char = 1;code = 49
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char = t;code = 116
char = o;code = 111
char = ;code = 32
char = <;code = 60
char = o;code = 111
char = r;code = 114
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char = +;code = 43
char = 1;code = 49
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char = ;;code = 59
char = ;code = 32
char = (;code = 40
char = 4;code = 52
char = );code = 41
char = ;code = 32
char = m;code = 109
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char = l;code = 108
char = d;code = 100
char = l;code = 108
char = y;code = 121
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char = i;code = 105
char = m;code = 109
char = p;code = 112
char = r;code = 114
char = o;code = 111
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char = e;code = 101
char = d;code = 100
char = ;code = 32
char = s;code = 115
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char = e;code = 101
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char = (;code = 40
char = >;code = 62
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char = 1;code = 49
char = ;code = 32
char = t;code = 116
char = o;code = 111
char = ;code = 32
char = <;code = 60
char = o;code = 111
char = r;code = 114
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char = +;code = 43
char = 5;code = 53
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char = ,;code = 44
char = ;code = 32
char = a;code = 97
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char = d;code = 100
char = ;code = 32
char = (;code = 40
char = 5;code = 53
char = );code = 41
char = ;code = 32
char = s;code = 115
char = i;code = 105
char = g;code = 103
char = n;code = 110
char = i;code = 105
char = f;code = 102
char = i;code = 105
char = c;code = 99
char = a;code = 97
char = n;code = 110
char = t;code = 116
char = l;code = 108
char = y;code = 121
char = ;code = 32
char = i;code = 105
char = m;code = 109
char = p;code = 112
char = r;code = 114
char = o;code = 111
char = v;code = 118
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = s;code = 115
char = l;code = 108
char = o;code = 111
char = p;code = 112
char = e;code = 101
char = ;code = 32
char = (;code = 40
char = >;code = 62
char = o;code = 111
char = r;code = 114
char = =;code = 61
char = +;code = 43
char = 5;code = 53
char = );code = 41
char = .;code = 46
char = <;code = 60
char = b;code = 98
char = r;code = 114
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char = >;code = 62
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = R;code = 82
char = E;code = 69
char = S;code = 83
char = U;code = 85
char = L;code = 76
char = T;code = 84
char = S;code = 83
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
char = b;code = 98
char = >;code = 62
char = A;code = 65
char = t;code = 116
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = f;code = 102
char = i;code = 105
char = r;code = 114
char = s;code = 115
char = t;code = 116
char = ;code = 32
char = n;code = 110
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char = p;code = 112
char = h;code = 104
char = r;code = 114
char = o;code = 111
char = l;code = 108
char = o;code = 111
char = g;code = 103
char = y;code = 121
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char = r;code = 114
char = e;code = 101
char = f;code = 102
char = e;code = 101
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char = r;code = 114
char = a;code = 97
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char = 8;code = 56
char = %;code = 37
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char = f;code = 102
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
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char = p;code = 112
char = a;code = 97
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char = i;code = 105
char = e;code = 101
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char = t;code = 116
char = s;code = 115
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char = w;code = 119
char = e;code = 101
char = r;code = 114
char = e;code = 101
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char = o;code = 111
char = n;code = 110
char = ;code = 32
char = C;code = 67
char = K;code = 75
char = D;code = 68
char = ;code = 32
char = s;code = 115
char = t;code = 116
char = a;code = 97
char = g;code = 103
char = e;code = 101
char = ;code = 32
char = 2;code = 50
char = ;code = 32
char = (;code = 40
char = e;code = 101
char = G;code = 71
char = F;code = 70
char = R;code = 82
char = :;code = 58
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char = 9;code = 57
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char = -;code = 45
char = 6;code = 54
char = 0;code = 48
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char = m;code = 109
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char = ,;code = 44
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char = 4;code = 52
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char = .;code = 46
char = 7;code = 55
char = %;code = 37
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char = o;code = 111
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char = C;code = 67
char = K;code = 75
char = D;code = 68
char = ;code = 32
char = s;code = 115
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char = a;code = 97
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char = 3;code = 51
char = ;code = 32
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char = e;code = 101
char = G;code = 71
char = F;code = 70
char = R;code = 82
char = :;code = 58
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char = 5;code = 53
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char = -;code = 45
char = 3;code = 51
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char = m;code = 109
char = l;code = 108
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char = m;code = 109
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char = ,;code = 44
char = ;code = 32
char = a;code = 97
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char = d;code = 100
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char = 4;code = 52
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char = .;code = 46
char = 5;code = 53
char = %;code = 37
char = ;code = 32
char = o;code = 111
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char = C;code = 67
char = K;code = 75
char = D;code = 68
char = ;code = 32
char = s;code = 115
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char = a;code = 97
char = g;code = 103
char = e;code = 101
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char = 4;code = 52
char = ;code = 32
char = (;code = 40
char = e;code = 101
char = G;code = 71
char = F;code = 70
char = R;code = 82
char = :;code = 58
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char = 2;code = 50
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char = 1;code = 49
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char = ;code = 32
char = m;code = 109
char = l;code = 108
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char = m;code = 109
char = );code = 41
char = ;code = 32
char = C;code = 67
char = K;code = 75
char = D;code = 68
char = .;code = 46
char = ;code = 32
char = S;code = 83
char = i;code = 105
char = g;code = 103
char = n;code = 110
char = i;code = 105
char = f;code = 102
char = i;code = 105
char = c;code = 99
char = a;code = 97
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char = l;code = 108
char = y;code = 121
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char = i;code = 105
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char = p;code = 112
char = r;code = 114
char = o;code = 111
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char = d;code = 100
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char = e;code = 101
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char = 4;code = 52
char = 8;code = 56
char = .;code = 46
char = 2;code = 50
char = %;code = 37
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = C;code = 67
char = K;code = 75
char = D;code = 68
char = ;code = 32
char = s;code = 115
char = t;code = 116
char = a;code = 97
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char = a;code = 97
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char = i;code = 105
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char = s;code = 115
char = ,;code = 44
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char = 2;code = 50
char = 9;code = 57
char = .;code = 46
char = 3;code = 51
char = %;code = 37
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = C;code = 67
char = K;code = 75
char = D;code = 68
char = ;code = 32
char = s;code = 115
char = t;code = 116
char = a;code = 97
char = g;code = 103
char = e;code = 101
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char = 3;code = 51
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char = p;code = 112
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = e;code = 101
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char = s;code = 115
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char = ;code = 32
char = a;code = 97
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char = d;code = 100
char = ;code = 32
char = o;code = 111
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char = l;code = 108
char = y;code = 121
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char = 1;code = 49
char = 4;code = 52
char = .;code = 46
char = 7;code = 55
char = %;code = 37
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = C;code = 67
char = K;code = 75
char = D;code = 68
char = ;code = 32
char = s;code = 115
char = t;code = 116
char = a;code = 97
char = g;code = 103
char = e;code = 101
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char = 4;code = 52
char = ;code = 32
char = p;code = 112
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = e;code = 101
char = n;code = 110
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char = s;code = 115
char = ;code = 32
char = (;code = 40
char = P;code = 80
char = <;code = 60
char = 0;code = 48
char = .;code = 46
char = 0;code = 48
char = 5;code = 53
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char = .;code = 46
char = ;code = 32
char = B;code = 66
char = e;code = 101
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char = n;code = 110
char = g;code = 103
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char = i;code = 105
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char = t;code = 116
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char = e;code = 101
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char = s;code = 115
char = t;code = 116
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char = e;code = 101
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char = u;code = 117
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char = l;code = 108
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char = s;code = 115
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char = g;code = 103
char = r;code = 114
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char = s;code = 115
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char = o;code = 111
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char = a;code = 97
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char = a;code = 97
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char = s;code = 115
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char = w;code = 119
char = h;code = 104
char = e;code = 101
char = r;code = 114
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char = a;code = 97
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char = a;code = 97
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char = e;code = 101
char = ,;code = 44
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char = g;code = 103
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char = o;code = 111
char = f;code = 102
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char = i;code = 105
char = o;code = 111
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char = ,;code = 44
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char = a;code = 97
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char = d;code = 100
char = i;code = 105
char = a;code = 97
char = b;code = 98
char = e;code = 101
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char = e;code = 101
char = s;code = 115
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char = m;code = 109
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char = l;code = 108
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char = d;code = 100
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char = r;code = 114
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char = a;code = 97
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char = t;code = 116
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char = v;code = 118
char = e;code = 101
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = s;code = 115
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char = g;code = 103
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char = f;code = 102
char = i;code = 105
char = c;code = 99
char = a;code = 97
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char = c;code = 99
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char = .;code = 46
char = <;code = 60
char = b;code = 98
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char = >;code = 62
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = C;code = 67
char = O;code = 79
char = N;code = 78
char = C;code = 67
char = L;code = 76
char = U;code = 85
char = S;code = 83
char = I;code = 73
char = O;code = 79
char = N;code = 78
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
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char = s;code = 115
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result sql = BACKGROUND : The adverse effects arising from late referral to a nephrologist of patients with chronic kidney disease (CKD) are well known. Retrospectively we examined the initial characteristics of patients referred in various stages of CKD to our nephrology division and tried to identify potential baseline factors associated with subsequent changes in estimated glomerular filtration rate (eGFR).
PATIENTS AND METHODS : Between September 1997 and June 2006 1,443 patients (909 male, 534 female) with CKD, with eGFRs ranging from 15 to 89 ml/min, were referred to our nephrology division and categorized using the National Kidney Foundation classification for CKD based on eGFR. The slope of eGFR change (ml/min-1/1.73/m2-1/year-1) was determined by linear regression analysis and the patients were divided into five groups: (1) significantly progressive slope (deterioration) (more negative than -5 ml/min/year); (2) mildly progressive slope (>-5 to -1 to +1 to or=+5).
RESULTS : At the first nephrology referral, 5.8% of the patients were on CKD stage 2 (eGFR: 90-60 ml/m), 46.7% on CKD stage 3 (eGFR: 59-30 ml/m), and 47.5% on CKD stage 4 (eGFR: 29-15 ml/m) CKD. Significantly improved slope was detected in 48.2% of CKD stage 2 patients, 29.3% of CKD stage 3 patients, and only 14.7% of CKD stage 4 patients (P<0.05). Being in stage 4 or stage 3 versus being in stage 2 significantly reduced the likelihood of an improved slope in logistic regression analysis whereas age, gender, presence of hypertension, and diabetes mellitus did not reach the level of significance.
CONCLUSION : Referral to a nephrology clinic can lead not only to arrest of progression of CKD but also to regression/improvement. Early referral is a positive predictive factor for improvement in eGFR, which emphasizes the importance of such referral. The previously held idea that, once established, CKD progresses invariably is not valid anymore.
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char = n;code = 110
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result sql = Improvement in eGFR in patients with chronic kidney disease attending a nephrology clinic.
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char = <;code = 60
char = /;code = 47
char = b;code = 98
char = >;code = 62
char = B;code = 66
char = e;code = 101
char = t;code = 116
char = w;code = 119
char = e;code = 101
char = e;code = 101
char = n;code = 110
char = ;code = 32
char = S;code = 83
char = e;code = 101
char = p;code = 112
char = t;code = 116
char = e;code = 101
char = m;code = 109
char = b;code = 98
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = 1;code = 49
char = 9;code = 57
char = 9;code = 57
char = 7;code = 55
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = J;code = 74
char = u;code = 117
char = n;code = 110
char = e;code = 101
char = ;code = 32
char = 2;code = 50
char = 0;code = 48
char = 0;code = 48
char = 6;code = 54
char = ;code = 32
char = 1;code = 49
char = ,;code = 44
char = 4;code = 52
char = 4;code = 52
char = 3;code = 51
char = ;code = 32
char = p;code = 112
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = s;code = 115
char = ;code = 32
char = (;code = 40
char = 9;code = 57
char = 0;code = 48
char = 9;code = 57
char = ;code = 32
char = m;code = 109
char = a;code = 97
char = l;code = 108
char = e;code = 101
char = ,;code = 44
char = ;code = 32
char = 5;code = 53
char = 3;code = 51
char = 4;code = 52
char = ;code = 32
char = f;code = 102
char = e;code = 101
char = m;code = 109
char = a;code = 97
char = l;code = 108
char = e;code = 101
char = );code = 41
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = C;code = 67
char = K;code = 75
char = D;code = 68
char = ,;code = 44
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = e;code = 101
char = G;code = 71
char = F;code = 70
char = R;code = 82
char = s;code = 115
char = ;code = 32
char = r;code = 114
char = a;code = 97
char = n;code = 110
char = g;code = 103
char = i;code = 105
char = n;code = 110
char = g;code = 103
char = ;code = 32
char = f;code = 102
char = r;code = 114
char = o;code = 111
char = m;code = 109
char = ;code = 32
char = 1;code = 49
char = 5;code = 53
char = ;code = 32
char = t;code = 116
char = o;code = 111
char = ;code = 32
char = 8;code = 56
char = 9;code = 57
char = ;code = 32
char = m;code = 109
char = l;code = 108
char = /;code = 47
char = m;code = 109
char = i;code = 105
char = n;code = 110
char = ,;code = 44
char = ;code = 32
char = w;code = 119
char = e;code = 101
char = r;code = 114
char = e;code = 101
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = f;code = 102
char = e;code = 101
char = r;code = 114
char = r;code = 114
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = t;code = 116
char = o;code = 111
char = ;code = 32
char = o;code = 111
char = u;code = 117
char = r;code = 114
char = ;code = 32
char = n;code = 110
char = e;code = 101
char = p;code = 112
char = h;code = 104
char = r;code = 114
char = o;code = 111
char = l;code = 108
char = o;code = 111
char = g;code = 103
char = y;code = 121
char = ;code = 32
char = d;code = 100
char = i;code = 105
char = v;code = 118
char = i;code = 105
char = s;code = 115
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = c;code = 99
char = a;code = 97
char = t;code = 116
char = e;code = 101
char = g;code = 103
char = o;code = 111
char = r;code = 114
char = i;code = 105
char = z;code = 122
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = u;code = 117
char = s;code = 115
char = i;code = 105
char = n;code = 110
char = g;code = 103
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = N;code = 78
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = K;code = 75
char = i;code = 105
char = d;code = 100
char = n;code = 110
char = e;code = 101
char = y;code = 121
char = ;code = 32
char = F;code = 70
char = o;code = 111
char = u;code = 117
char = n;code = 110
char = d;code = 100
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = c;code = 99
char = l;code = 108
char = a;code = 97
char = s;code = 115
char = s;code = 115
char = i;code = 105
char = f;code = 102
char = i;code = 105
char = c;code = 99
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = f;code = 102
char = o;code = 111
char = r;code = 114
char = ;code = 32
char = C;code = 67
char = K;code = 75
char = D;code = 68
char = ;code = 32
char = b;code = 98
char = a;code = 97
char = s;code = 115
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = e;code = 101
char = G;code = 71
char = F;code = 70
char = R;code = 82
char = .;code = 46
char = ;code = 32
char = T;code = 84
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = s;code = 115
char = l;code = 108
char = o;code = 111
char = p;code = 112
char = e;code = 101
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = e;code = 101
char = G;code = 71
char = F;code = 70
char = R;code = 82
char = ;code = 32
char = c;code = 99
char = h;code = 104
char = a;code = 97
char = n;code = 110
char = g;code = 103
char = e;code = 101
char = ;code = 32
char = (;code = 40
char = m;code = 109
char = l;code = 108
char = /;code = 47
char = m;code = 109
char = i;code = 105
char = n;code = 110
char = -;code = 45
char = 1;code = 49
char = /;code = 47
char = 1;code = 49
char = .;code = 46
char = 7;code = 55
char = 3;code = 51
char = /;code = 47
char = m;code = 109
char = 2;code = 50
char = -;code = 45
char = 1;code = 49
char = /;code = 47
char = y;code = 121
char = e;code = 101
char = a;code = 97
char = r;code = 114
char = -;code = 45
char = 1;code = 49
char = );code = 41
char = ;code = 32
char = w;code = 119
char = a;code = 97
char = s;code = 115
char = ;code = 32
char = d;code = 100
char = e;code = 101
char = t;code = 116
char = e;code = 101
char = r;code = 114
char = m;code = 109
char = i;code = 105
char = n;code = 110
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = b;code = 98
char = y;code = 121
char = ;code = 32
char = l;code = 108
char = i;code = 105
char = n;code = 110
char = e;code = 101
char = a;code = 97
char = r;code = 114
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = g;code = 103
char = r;code = 114
char = e;code = 101
char = s;code = 115
char = s;code = 115
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = a;code = 97
char = l;code = 108
char = y;code = 121
char = s;code = 115
char = i;code = 105
char = s;code = 115
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = p;code = 112
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = s;code = 115
char = ;code = 32
char = w;code = 119
char = e;code = 101
char = r;code = 114
char = e;code = 101
char = ;code = 32
char = d;code = 100
char = i;code = 105
char = v;code = 118
char = i;code = 105
char = d;code = 100
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = t;code = 116
char = o;code = 111
char = ;code = 32
char = f;code = 102
char = i;code = 105
char = v;code = 118
char = e;code = 101
char = ;code = 32
char = g;code = 103
char = r;code = 114
char = o;code = 111
char = u;code = 117
char = p;code = 112
char = s;code = 115
char = :;code = 58
char = ;code = 32
char = (;code = 40
char = 1;code = 49
char = );code = 41
char = ;code = 32
char = s;code = 115
char = i;code = 105
char = g;code = 103
char = n;code = 110
char = i;code = 105
char = f;code = 102
char = i;code = 105
char = c;code = 99
char = a;code = 97
char = n;code = 110
char = t;code = 116
char = l;code = 108
char = y;code = 121
char = ;code = 32
char = p;code = 112
char = r;code = 114
char = o;code = 111
char = g;code = 103
char = r;code = 114
char = e;code = 101
char = s;code = 115
char = s;code = 115
char = i;code = 105
char = v;code = 118
char = e;code = 101
char = ;code = 32
char = s;code = 115
char = l;code = 108
char = o;code = 111
char = p;code = 112
char = e;code = 101
char = ;code = 32
char = (;code = 40
char = d;code = 100
char = e;code = 101
char = t;code = 116
char = e;code = 101
char = r;code = 114
char = i;code = 105
char = o;code = 111
char = r;code = 114
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = );code = 41
char = ;code = 32
char = (;code = 40
char = m;code = 109
char = o;code = 111
char = r;code = 114
char = e;code = 101
char = ;code = 32
char = n;code = 110
char = e;code = 101
char = g;code = 103
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = v;code = 118
char = e;code = 101
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = a;code = 97
char = n;code = 110
char = ;code = 32
char = -;code = 45
char = 5;code = 53
char = ;code = 32
char = m;code = 109
char = l;code = 108
char = /;code = 47
char = m;code = 109
char = i;code = 105
char = n;code = 110
char = /;code = 47
char = y;code = 121
char = e;code = 101
char = a;code = 97
char = r;code = 114
char = );code = 41
char = ;;code = 59
char = ;code = 32
char = (;code = 40
char = 2;code = 50
char = );code = 41
char = ;code = 32
char = m;code = 109
char = i;code = 105
char = l;code = 108
char = d;code = 100
char = l;code = 108
char = y;code = 121
char = ;code = 32
char = p;code = 112
char = r;code = 114
char = o;code = 111
char = g;code = 103
char = r;code = 114
char = e;code = 101
char = s;code = 115
char = s;code = 115
char = i;code = 105
char = v;code = 118
char = e;code = 101
char = ;code = 32
char = s;code = 115
char = l;code = 108
char = o;code = 111
char = p;code = 112
char = e;code = 101
char = ;code = 32
char = (;code = 40
char = >;code = 62
char = -;code = 45
char = 5;code = 53
char = ;code = 32
char = t;code = 116
char = o;code = 111
char = ;code = 32
char = <;code = 60
char = o;code = 111
char = r;code = 114
char = =;code = 61
char = -;code = 45
char = 1;code = 49
char = );code = 41
char = ;;code = 59
char = ;code = 32
char = (;code = 40
char = 3;code = 51
char = );code = 41
char = ;code = 32
char = s;code = 115
char = t;code = 116
char = a;code = 97
char = b;code = 98
char = l;code = 108
char = e;code = 101
char = ;code = 32
char = s;code = 115
char = l;code = 108
char = o;code = 111
char = p;code = 112
char = e;code = 101
char = ;code = 32
char = (;code = 40
char = >;code = 62
char = -;code = 45
char = 1;code = 49
char = ;code = 32
char = t;code = 116
char = o;code = 111
char = ;code = 32
char = <;code = 60
char = o;code = 111
char = r;code = 114
char = =;code = 61
char = +;code = 43
char = 1;code = 49
char = );code = 41
char = ;;code = 59
char = ;code = 32
char = (;code = 40
char = 4;code = 52
char = );code = 41
char = ;code = 32
char = m;code = 109
char = i;code = 105
char = l;code = 108
char = d;code = 100
char = l;code = 108
char = y;code = 121
char = ;code = 32
char = i;code = 105
char = m;code = 109
char = p;code = 112
char = r;code = 114
char = o;code = 111
char = v;code = 118
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = s;code = 115
char = l;code = 108
char = o;code = 111
char = p;code = 112
char = e;code = 101
char = ;code = 32
char = (;code = 40
char = >;code = 62
char = +;code = 43
char = 1;code = 49
char = ;code = 32
char = t;code = 116
char = o;code = 111
char = ;code = 32
char = <;code = 60
char = o;code = 111
char = r;code = 114
char = =;code = 61
char = +;code = 43
char = 5;code = 53
char = );code = 41
char = ,;code = 44
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = (;code = 40
char = 5;code = 53
char = );code = 41
char = ;code = 32
char = s;code = 115
char = i;code = 105
char = g;code = 103
char = n;code = 110
char = i;code = 105
char = f;code = 102
char = i;code = 105
char = c;code = 99
char = a;code = 97
char = n;code = 110
char = t;code = 116
char = l;code = 108
char = y;code = 121
char = ;code = 32
char = i;code = 105
char = m;code = 109
char = p;code = 112
char = r;code = 114
char = o;code = 111
char = v;code = 118
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = s;code = 115
char = l;code = 108
char = o;code = 111
char = p;code = 112
char = e;code = 101
char = ;code = 32
char = (;code = 40
char = >;code = 62
char = o;code = 111
char = r;code = 114
char = =;code = 61
char = +;code = 43
char = 5;code = 53
char = );code = 41
char = .;code = 46
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = R;code = 82
char = E;code = 69
char = S;code = 83
char = U;code = 85
char = L;code = 76
char = T;code = 84
char = S;code = 83
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
char = b;code = 98
char = >;code = 62
char = A;code = 65
char = t;code = 116
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = f;code = 102
char = i;code = 105
char = r;code = 114
char = s;code = 115
char = t;code = 116
char = ;code = 32
char = n;code = 110
char = e;code = 101
char = p;code = 112
char = h;code = 104
char = r;code = 114
char = o;code = 111
char = l;code = 108
char = o;code = 111
char = g;code = 103
char = y;code = 121
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = f;code = 102
char = e;code = 101
char = r;code = 114
char = r;code = 114
char = a;code = 97
char = l;code = 108
char = ,;code = 44
char = ;code = 32
char = 5;code = 53
char = .;code = 46
char = 8;code = 56
char = %;code = 37
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = p;code = 112
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = s;code = 115
char = ;code = 32
char = w;code = 119
char = e;code = 101
char = r;code = 114
char = e;code = 101
char = ;code = 32
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = C;code = 67
char = K;code = 75
char = D;code = 68
char = ;code = 32
char = s;code = 115
char = t;code = 116
char = a;code = 97
char = g;code = 103
char = e;code = 101
char = ;code = 32
char = 2;code = 50
char = ;code = 32
char = (;code = 40
char = e;code = 101
char = G;code = 71
char = F;code = 70
char = R;code = 82
char = :;code = 58
char = ;code = 32
char = 9;code = 57
char = 0;code = 48
char = -;code = 45
char = 6;code = 54
char = 0;code = 48
char = ;code = 32
char = m;code = 109
char = l;code = 108
char = /;code = 47
char = m;code = 109
char = );code = 41
char = ,;code = 44
char = ;code = 32
char = 4;code = 52
char = 6;code = 54
char = .;code = 46
char = 7;code = 55
char = %;code = 37
char = ;code = 32
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = C;code = 67
char = K;code = 75
char = D;code = 68
char = ;code = 32
char = s;code = 115
char = t;code = 116
char = a;code = 97
char = g;code = 103
char = e;code = 101
char = ;code = 32
char = 3;code = 51
char = ;code = 32
char = (;code = 40
char = e;code = 101
char = G;code = 71
char = F;code = 70
char = R;code = 82
char = :;code = 58
char = ;code = 32
char = 5;code = 53
char = 9;code = 57
char = -;code = 45
char = 3;code = 51
char = 0;code = 48
char = ;code = 32
char = m;code = 109
char = l;code = 108
char = /;code = 47
char = m;code = 109
char = );code = 41
char = ,;code = 44
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = 4;code = 52
char = 7;code = 55
char = .;code = 46
char = 5;code = 53
char = %;code = 37
char = ;code = 32
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = C;code = 67
char = K;code = 75
char = D;code = 68
char = ;code = 32
char = s;code = 115
char = t;code = 116
char = a;code = 97
char = g;code = 103
char = e;code = 101
char = ;code = 32
char = 4;code = 52
char = ;code = 32
char = (;code = 40
char = e;code = 101
char = G;code = 71
char = F;code = 70
char = R;code = 82
char = :;code = 58
char = ;code = 32
char = 2;code = 50
char = 9;code = 57
char = -;code = 45
char = 1;code = 49
char = 5;code = 53
char = ;code = 32
char = m;code = 109
char = l;code = 108
char = /;code = 47
char = m;code = 109
char = );code = 41
char = ;code = 32
char = C;code = 67
char = K;code = 75
char = D;code = 68
char = .;code = 46
char = ;code = 32
char = S;code = 83
char = i;code = 105
char = g;code = 103
char = n;code = 110
char = i;code = 105
char = f;code = 102
char = i;code = 105
char = c;code = 99
char = a;code = 97
char = n;code = 110
char = t;code = 116
char = l;code = 108
char = y;code = 121
char = ;code = 32
char = i;code = 105
char = m;code = 109
char = p;code = 112
char = r;code = 114
char = o;code = 111
char = v;code = 118
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = s;code = 115
char = l;code = 108
char = o;code = 111
char = p;code = 112
char = e;code = 101
char = ;code = 32
char = w;code = 119
char = a;code = 97
char = s;code = 115
char = ;code = 32
char = d;code = 100
char = e;code = 101
char = t;code = 116
char = e;code = 101
char = c;code = 99
char = t;code = 116
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = 4;code = 52
char = 8;code = 56
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result sql = BACKGROUND : The adverse effects arising from late referral to a nephrologist of patients with chronic kidney disease (CKD) are well known. Retrospectively we examined the initial characteristics of patients referred in various stages of CKD to our nephrology division and tried to identify potential baseline factors associated with subsequent changes in estimated glomerular filtration rate (eGFR).
PATIENTS AND METHODS : Between September 1997 and June 2006 1,443 patients (909 male, 534 female) with CKD, with eGFRs ranging from 15 to 89 ml/min, were referred to our nephrology division and categorized using the National Kidney Foundation classification for CKD based on eGFR. The slope of eGFR change (ml/min-1/1.73/m2-1/year-1) was determined by linear regression analysis and the patients were divided into five groups: (1) significantly progressive slope (deterioration) (more negative than -5 ml/min/year); (2) mildly progressive slope (>-5 to
RESULTS : At the first nephrology referral, 5.8% of the patients were on CKD stage 2 (eGFR: 90-60 ml/m), 46.7% on CKD stage 3 (eGFR: 59-30 ml/m), and 47.5% on CKD stage 4 (eGFR: 29-15 ml/m) CKD. Significantly improved slope was detected in 48.2% of CKD stage 2 patients, 29.3% of CKD stage 3 patients, and only 14.7% of CKD stage 4 patients (P<0.05). Being in stage 4 or stage 3 versus being in stage 2 significantly reduced the likelihood of an improved slope in logistic regression analysis whereas age, gender, presence of hypertension, and diabetes mellitus did not reach the level of significance.
CONCLUSION : Referral to a nephrology clinic can lead not only to arrest of progression of CKD but also to regression/improvement. Early referral is a positive predictive factor for improvement in eGFR, which emphasizes the importance of such referral. The previously held idea that, once established, CKD progresses invariably is not valid anymore.
Publication: Int Urol Nephrol 2008 ;40(3)::841-8. :doi: 10.1007/s11255-008-9360-9.
Publication Date: 2008
Study Author(s): Taskapan, Hulya;Tam, Paul;Au, Victoria;Chow, Stephen;Fung, Jason;Nagai, Gordon;Roscoe, Janet;Ng, Paul;Sikaneta, Tabo;Ting, Robert;Oreopoulos, Dimitrios G;
Institution: Nephrology, Scarborough General Hospital Toronto, 78 Corporate Drive 10, Scarborough, Toronto, ON, Canada M1H3GH.
Shortcut link to this study:
Publication Date: 2008
Study Author(s): Taskapan, Hulya;Tam, Paul;Au, Victoria;Chow, Stephen;Fung, Jason;Nagai, Gordon;Roscoe, Janet;Ng, Paul;Sikaneta, Tabo;Ting, Robert;Oreopoulos, Dimitrios G;
Institution: Nephrology, Scarborough General Hospital Toronto, 78 Corporate Drive 10, Scarborough, Toronto, ON, Canada M1H3GH.
Shortcut link to this study:
BACKGROUND : The adverse effects arising from late referral to a nephrologist of patients with chronic kidney disease (CKD) are well known. Retrospectively we examined the initial characteristics of patients referred in various stages of CKD to our nephrology division and tried to identify potential baseline factors associated with subsequent changes in estimated glomerular filtration rate (eGFR).
PATIENTS AND METHODS : Between September 1997 and June 2006 1,443 patients (909 male, 534 female) with CKD, with eGFRs ranging from 15 to 89 ml/min, were referred to our nephrology division and categorized using the National Kidney Foundation classification for CKD based on eGFR. The slope of eGFR change (ml/min-1/1.73/m2-1/year-1) was determined by linear regression analysis and the patients were divided into five groups: (1) significantly progressive slope (deterioration) (more negative than -5 ml/min/year); (2) mildly progressive slope (>-5 to-1 to +1 to or=+5).
RESULTS : At the first nephrology referral, 5.8% of the patients were on CKD stage 2 (eGFR: 90-60 ml/m), 46.7% on CKD stage 3 (eGFR: 59-30 ml/m), and 47.5% on CKD stage 4 (eGFR: 29-15 ml/m) CKD. Significantly improved slope was detected in 48.2% of CKD stage 2 patients, 29.3% of CKD stage 3 patients, and only 14.7% of CKD stage 4 patients (P<0.05). Being in stage 4 or stage 3 versus being in stage 2 significantly reduced the likelihood of an improved slope in logistic regression analysis whereas age, gender, presence of hypertension, and diabetes mellitus did not reach the level of significance.
CONCLUSION : Referral to a nephrology clinic can lead not only to arrest of progression of CKD but also to regression/improvement. Early referral is a positive predictive factor for improvement in eGFR, which emphasizes the importance of such referral. The previously held idea that, once established, CKD progresses invariably is not valid anymore.
PATIENTS AND METHODS : Between September 1997 and June 2006 1,443 patients (909 male, 534 female) with CKD, with eGFRs ranging from 15 to 89 ml/min, were referred to our nephrology division and categorized using the National Kidney Foundation classification for CKD based on eGFR. The slope of eGFR change (ml/min-1/1.73/m2-1/year-1) was determined by linear regression analysis and the patients were divided into five groups: (1) significantly progressive slope (deterioration) (more negative than -5 ml/min/year); (2) mildly progressive slope (>-5 to
RESULTS : At the first nephrology referral, 5.8% of the patients were on CKD stage 2 (eGFR: 90-60 ml/m), 46.7% on CKD stage 3 (eGFR: 59-30 ml/m), and 47.5% on CKD stage 4 (eGFR: 29-15 ml/m) CKD. Significantly improved slope was detected in 48.2% of CKD stage 2 patients, 29.3% of CKD stage 3 patients, and only 14.7% of CKD stage 4 patients (P<0.05). Being in stage 4 or stage 3 versus being in stage 2 significantly reduced the likelihood of an improved slope in logistic regression analysis whereas age, gender, presence of hypertension, and diabetes mellitus did not reach the level of significance.
CONCLUSION : Referral to a nephrology clinic can lead not only to arrest of progression of CKD but also to regression/improvement. Early referral is a positive predictive factor for improvement in eGFR, which emphasizes the importance of such referral. The previously held idea that, once established, CKD progresses invariably is not valid anymore.
PMID: 18386153
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