char = C;code = 67 char = l;code = 108 char = i;code = 105 char = n;code = 110 char = i;code = 105 char = c;code = 99 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = f;code = 102 char = i;code = 105 char = e;code = 101 char = l;code = 108 char = d;code = 100 char = ;code = 32 char = s;code = 115 char = t;code = 116 char = u;code = 117 char = d;code = 100 char = y;code = 121 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = s;code = 115 char = a;code = 97 char = f;code = 102 char = e;code = 101 char = t;code = 116 char = y;code = 121 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = e;code = 101 char = f;code = 102 char = f;code = 102 char = i;code = 105 char = c;code = 99 char = a;code = 97 char = c;code = 99 char = y;code = 121 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = s;code = 115 char = p;code = 112 char = i;code = 105 char = n;code = 110 char = o;code = 111 char = s;code = 115 char = a;code = 97 char = d;code = 100 char = ;code = 32 char = c;code = 99 char = h;code = 104 char = e;code = 101 char = w;code = 119 char = a;code = 97 char = b;code = 98 char = l;code = 108 char = e;code = 101 char = ;code = 32 char = t;code = 116 char = a;code = 97 char = b;code = 98 char = l;code = 108 char = e;code = 101 char = t;code = 116 char = s;code = 115 char = ;code = 32 char = f;code = 102 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = t;code = 116 char = r;code = 114 char = o;code = 111 char = l;code = 108 char = l;code = 108 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = ;code = 32 char = f;code = 102 char = l;code = 108 char = e;code = 101 char = a;code = 97 char = s;code = 115 char = ;code = 32 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = d;code = 100 char = o;code = 111 char = g;code = 103 char = s;code = 115 char = .;code = 46 result sql = Clinical field study of the safety and efficacy of spinosad chewable tablets for controlling fleas on dogs.
Clinical field study of the safety and efficacy of spinosad chewable tablets for controlling fleas on dogs.char = P;code = 80 char = r;code = 114 char = e;code = 101 char = l;code = 108 char = i;code = 105 char = m;code = 109 char = i;code = 105 char = n;code = 110 char = a;code = 97 char = r;code = 114 char = y;code = 121 char = ;code = 32 char = S;code = 83 char = t;code = 116 char = u;code = 117 char = d;code = 100 char = i;code = 105 char = e;code = 101 char = s;code = 115 char = ;code = 32 char = s;code = 115 char = h;code = 104 char = o;code = 111 char = w;code = 119 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = s;code = 115 char = p;code = 112 char = i;code = 105 char = n;code = 110 char = o;code = 111 char = s;code = 115 char = a;code = 97 char = d;code = 100 char = ;code = 32 char = t;code = 116 char = o;code = 111 char = ;code = 32 char = b;code = 98 char = e;code = 101 char = ;code = 32 char = r;code = 114 char = a;code = 97 char = p;code = 112 char = i;code = 105 char = d;code = 100 char = l;code = 108 char = y;code = 121 char = ;code = 32 char = e;code = 101 char = f;code = 102 char = f;code = 102 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = e;code = 101 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = s;code = 115 char = a;code = 97 char = f;code = 102 char = e;code = 101 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = t;code = 116 char = r;code = 114 char = o;code = 111 char = l;code = 108 char = l;code = 108 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = ;code = 32 char = f;code = 102 char = l;code = 108 char = e;code = 101 char = a;code = 97 char = s;code = 115 char = ;code = 32 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = d;code = 100 char = o;code = 111 char = g;code = 103 char = s;code = 115 char = .;code = 46 char = ;code = 32 char = T;code = 84 char = o;code = 111 char = ;code = 32 char = v;code = 118 char = a;code = 97 char = l;code = 108 char = i;code = 105 char = d;code = 100 char = a;code = 97 char = t;code = 116 char = e;code = 101 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = s;code = 115 char = e;code = 101 char = ;code = 32 char = s;code = 115 char = t;code = 116 char = u;code = 117 char = d;code = 100 char = i;code = 105 char = e;code = 101 char = s;code = 115 char = ,;code = 44 char = ;code = 32 char = a;code = 97 char = ;code = 32 char = c;code = 99 char = l;code = 108 char = i;code = 105 char = n;code = 110 char = i;code = 105 char = c;code = 99 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = t;code = 116 char = r;code = 114 char = i;code = 105 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = w;code = 119 char = a;code = 97 char = s;code = 115 char = ;code = 32 char = u;code = 117 char = n;code = 110 char = d;code = 100 char = e;code = 101 char = r;code = 114 char = t;code = 116 char = a;code = 97 char = k;code = 107 char = e;code = 101 char = n;code = 110 char = ;code = 32 char = u;code = 117 char = s;code = 115 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = ;code = 32 char = 4;code = 52 char = 7;code = 55 char = 0;code = 48 char = ;code = 32 char = f;code = 102 char = l;code = 108 char = e;code = 101 char = a;code = 97 char = -;code = 45 char = i;code = 105 char = n;code = 110 char = f;code = 102 char = e;code = 101 char = s;code = 115 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = c;code = 99 char = l;code = 108 char = i;code = 105 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = -;code = 45 char = o;code = 111 char = w;code = 119 char = n;code = 110 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = d;code = 100 char = o;code = 111 char = g;code = 103 char = s;code = 115 char = ;code = 32 char = a;code = 97 char = l;code = 108 char = l;code = 108 char = o;code = 111 char = c;code = 99 char = a;code = 97 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = t;code = 116 char = o;code = 111 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = c;code = 99 char = e;code = 101 char = i;code = 105 char = v;code = 118 char = e;code = 101 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = r;code = 114 char = e;code = 101 char = e;code = 101 char = ;code = 32 char = m;code = 109 char = o;code = 111 char = n;code = 110 char = t;code = 116 char = h;code = 104 char = y;code = 121 char = ;code = 32 char = t;code = 116 char = r;code = 114 char = e;code = 101 char = a;code = 97 char = t;code = 116 char = m;code = 109 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = s;code = 115 char = ;code = 32 char = w;code = 119 char = i;code = 105 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = e;code = 101 char = i;code = 105 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = b;code = 98 char = e;code = 101 char = e;code = 101 char = f;code = 102 char = -;code = 45 char = f;code = 102 char = l;code = 108 char = a;code = 97 char = v;code = 118 char = o;code = 111 char = r;code = 114 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = c;code = 99 char = h;code = 104 char = e;code = 101 char = w;code = 119 char = a;code = 97 char = b;code = 98 char = l;code = 108 char = e;code = 101 char = ;code = 32 char = s;code = 115 char = p;code = 112 char = i;code = 105 char = n;code = 110 char = o;code = 111 char = s;code = 115 char = a;code = 97 char = d;code = 100 char = ;code = 32 char = t;code = 116 char = a;code = 97 char = b;code = 98 char = l;code = 108 char = e;code = 101 char = t;code = 116 char = s;code = 115 char = ;code = 32 char = (;code = 40 char = 3;code = 51 char = 0;code = 48 char = -;code = 45 char = 6;code = 54 char = 0;code = 48 char = ;code = 32 char = m;code = 109 char = g;code = 103 char = /;code = 47 char = k;code = 107 char = g;code = 103 char = );code = 41 char = ;code = 32 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = s;code = 115 char = e;code = 101 char = l;code = 108 char = a;code = 97 char = m;code = 109 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = a;code = 97 char = p;code = 112 char = p;code = 112 char = l;code = 108 char = i;code = 105 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = t;code = 116 char = o;code = 111 char = ;code = 32 char = l;code = 108 char = a;code = 97 char = b;code = 98 char = e;code = 101 char = l;code = 108 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = s;code = 115 char = t;code = 116 char = r;code = 114 char = u;code = 117 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = .;code = 46 char = ;code = 32 char = F;code = 70 char = l;code = 108 char = e;code = 101 char = a;code = 97 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = u;code = 117 char = n;code = 110 char = t;code = 116 char = s;code = 115 char = ;code = 32 char = 1;code = 49 char = 5;code = 53 char = ;code = 32 char = d;code = 100 char = a;code = 97 char = y;code = 121 char = s;code = 115 char = ;code = 32 char = a;code = 97 char = f;code = 102 char = t;code = 116 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = e;code = 101 char = n;code = 110 char = r;code = 114 char = o;code = 111 char = l;code = 108 char = l;code = 108 char = m;code = 109 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = ;code = 32 char = w;code = 119 char = e;code = 101 char = r;code = 114 char = e;code = 101 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = d;code = 100 char = u;code = 117 char = c;code = 99 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = b;code = 98 char = y;code = 121 char = ;code = 32 char = 9;code = 57 char = 8;code = 56 char = .;code = 46 char = 6;code = 54 char = %;code = 37 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = 9;code = 57 char = 0;code = 48 char = .;code = 46 char = 9;code = 57 char = %;code = 37 char = ;code = 32 char = f;code = 102 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = s;code = 115 char = p;code = 112 char = i;code = 105 char = n;code = 110 char = o;code = 111 char = s;code = 115 char = a;code = 97 char = d;code = 100 char = -;code = 45 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = s;code = 115 char = e;code = 101 char = l;code = 108 char = a;code = 97 char = m;code = 109 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = n;code = 110 char = -;code = 45 char = t;code = 116 char = r;code = 114 char = e;code = 101 char = a;code = 97 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = d;code = 100 char = o;code = 111 char = g;code = 103 char = s;code = 115 char = ,;code = 44 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = s;code = 115 char = p;code = 112 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = e;code = 101 char = l;code = 108 char = y;code = 121 char = ;;code = 59 char = ;code = 32 char = a;code = 97 char = t;code = 116 char = ;code = 32 char = 9;code = 57 char = 0;code = 48 char = ;code = 32 char = d;code = 100 char = a;code = 97 char = y;code = 121 char = s;code = 115 char = ,;code = 44 char = ;code = 32 char = f;code = 102 char = l;code = 108 char = e;code = 101 char = a;code = 97 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = u;code = 117 char = n;code = 110 char = t;code = 116 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = d;code = 100 char = u;code = 117 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = ;code = 32 char = w;code = 119 char = e;code = 101 char = r;code = 114 char = e;code = 101 char = ;code = 32 char = 9;code = 57 char = 9;code = 57 char = .;code = 46 char = 9;code = 57 char = %;code = 37 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = 9;code = 57 char = 8;code = 56 char = .;code = 46 char = 9;code = 57 char = %;code = 37 char = ,;code = 44 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = s;code = 115 char = p;code = 112 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = e;code = 101 char = l;code = 108 char = y;code = 121 char = .;code = 46 char = ;code = 32 char = C;code = 67 char = o;code = 111 char = m;code = 109 char = p;code = 112 char = a;code = 97 char = r;code = 114 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = w;code = 119 char = i;code = 105 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = b;code = 98 char = a;code = 97 char = s;code = 115 char = e;code = 101 char = l;code = 108 char = i;code = 105 char = n;code = 110 char = e;code = 101 char = ,;code = 44 char = ;code = 32 char = a;code = 97 char = l;code = 108 char = l;code = 108 char = ;code = 32 char = f;code = 102 char = l;code = 108 char = e;code = 101 char = a;code = 97 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = d;code = 100 char = u;code = 117 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = ;code = 32 char = w;code = 119 char = e;code = 101 char = r;code = 114 char = e;code = 101 char = ;code = 32 char = s;code = 115 char = i;code = 105 char = g;code = 103 char = n;code = 110 char = i;code = 105 char = f;code = 102 char = i;code = 105 char = c;code = 99 char = a;code = 97 char = n;code = 110 char = t;code = 116 char = ;code = 32 char = (;code = 40 char = P;code = 80 char = ;code = 32 char = l;code = 108 char = e;code = 101 char = s;code = 115 char = s;code = 115 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = a;code = 97 char = n;code = 110 char = ;code = 32 char = .;code = 46 char = 0;code = 48 char = 0;code = 48 char = 1;code = 49 char = );code = 41 char = ;code = 32 char = f;code = 102 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = b;code = 98 char = o;code = 111 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = p;code = 112 char = r;code = 114 char = o;code = 111 char = d;code = 100 char = u;code = 117 char = c;code = 99 char = t;code = 116 char = s;code = 115 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = s;code = 115 char = p;code = 112 char = i;code = 105 char = n;code = 110 char = o;code = 111 char = s;code = 115 char = a;code = 97 char = d;code = 100 char = ;code = 32 char = w;code = 119 char = a;code = 97 char = s;code = 115 char = ;code = 32 char = s;code = 115 char = i;code = 105 char = g;code = 103 char = n;code = 110 char = i;code = 105 char = f;code = 102 char = i;code = 105 char = c;code = 99 char = a;code = 97 char = n;code = 110 char = t;code = 116 char = l;code = 108 char = y;code = 121 char = ;code = 32 char = (;code = 40 char = P;code = 80 char = ;code = 32 char = l;code = 108 char = e;code = 101 char = s;code = 115 char = s;code = 115 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = a;code = 97 char = n;code = 110 char = ;code = 32 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = e;code = 101 char = q;code = 113 char = u;code = 117 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = t;code = 116 char = o;code = 111 char = ;code = 32 char = .;code = 46 char = 0;code = 48 char = 1;code = 49 char = 7;code = 55 char = 2;code = 50 char = );code = 41 char = ;code = 32 char = m;code = 109 char = o;code = 111 char = r;code = 114 char = e;code = 101 char = ;code = 32 char = e;code = 101 char = f;code = 102 char = f;code = 102 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = e;code = 101 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = a;code = 97 char = n;code = 110 char = ;code = 32 char = s;code = 115 char = e;code = 101 char = l;code = 108 char = a;code = 97 char = m;code = 109 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = a;code = 97 char = t;code = 116 char = ;code = 32 char = e;code = 101 char = a;code = 97 char = c;code = 99 char = h;code = 104 char = ;code = 32 char = p;code = 112 char = o;code = 111 char = s;code = 115 char = t;code = 116 char = e;code = 101 char = n;code = 110 char = r;code = 114 char = o;code = 111 char = l;code = 108 char = l;code = 108 char = m;code = 109 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = ;code = 32 char = f;code = 102 char = l;code = 108 char = e;code = 101 char = a;code = 97 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = u;code = 117 char = n;code = 110 char = t;code = 116 char = .;code = 46 char = <;code = 60 char = b;code = 98 char = r;code = 114 char = /;code = 47 char = >;code = 62 result sql = Preliminary Studies showed spinosad to be rapidly effective and safe in controlling fleas on dogs. To validate these studies, a clinical trial was undertaken using 470 flea-infested client-owned dogs allocated to receive three monthy treatments with either beef-flavored chewable spinosad tablets (30-60 mg/kg) or selamectin applied to label instructions. Flea counts 15 days after enrollment were reduced by 98.6% and 90.9% for spinosad- and selamectin-treated dogs, respectively; at 90 days, flea count reductions were 99.9% and 98.9%, respectively. Compared with baseline, all flea reductions were significant (P less than .001) for both products and spinosad was significantly (P less than or equal to .0172) more effective than selamectin at each postenrollment flea count.
Publication: Vet. Ther. 2008 Spring ;9(1)::26-36.
Publication Date: 2008 Spring
Study Author(s): Robertson-Plouch, Carol;Baker, Keith A;Hozak, Rebecca R;Zimmermann, Alan G;Parks, S Craig;Herr, Cory;Hart, Liane M;Jay, Jeff;Hutchens, Douglas E;Snyder, Daniel E;
Institution: Elanco Animal Health.
Shortcut link to this study:
Preliminary Studies showed spinosad to be rapidly effective and safe in controlling fleas on dogs. To validate these studies, a clinical trial was undertaken using 470 flea-infested client-owned dogs allocated to receive three monthy treatments with either beef-flavored chewable spinosad tablets (30-60 mg/kg) or selamectin applied to label instructions. Flea counts 15 days after enrollment were reduced by 98.6% and 90.9% for spinosad- and selamectin-treated dogs, respectively; at 90 days, flea count reductions were 99.9% and 98.9%, respectively. Compared with baseline, all flea reductions were significant (P less than .001) for both products and spinosad was significantly (P less than or equal to .0172) more effective than selamectin at each postenrollment flea count.
PMID: 18415944