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result sql = Prevalence of non-alcoholic fatty liver disease in children and relationship to metabolic syndrome, insulin resistance, and waist circumference.
Prevalence of non-alcoholic fatty liver disease in children and relationship to metabolic syndrome, insulin resistance, and waist circumference.
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char = y;code = 121
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char = i;code = 105
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char = ;code = 32
char = t;code = 116
char = r;code = 114
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char = ;code = 32
char = o;code = 111
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char = ;code = 32
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char = 0;code = 48
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char = e;code = 101
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char = r;code = 114
char = ;code = 32
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char = g;code = 103
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char = ,;code = 44
char = ;code = 32
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char = e;code = 101
char = r;code = 114
char = e;code = 101
char = a;code = 97
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char = W;code = 87
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char = t;code = 116
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char = ;code = 32
char = o;code = 111
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char = t;code = 116
char = ;code = 32
char = t;code = 116
char = o;code = 111
char = ;code = 32
char = b;code = 98
char = e;code = 101
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = d;code = 100
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char = p;code = 112
char = e;code = 101
char = n;code = 110
char = d;code = 100
char = e;code = 101
char = n;code = 110
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char = ;code = 32
char = r;code = 114
char = i;code = 105
char = s;code = 115
char = k;code = 107
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char = a;code = 97
char = c;code = 99
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char = r;code = 114
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char = f;code = 102
char = o;code = 111
char = r;code = 114
char = ;code = 32
char = N;code = 78
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char = L;code = 76
char = D;code = 68
char = ;code = 32
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char = a;code = 97
char = r;code = 114
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char = f;code = 102
char = ;code = 32
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char = e;code = 101
char = ;code = 32
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char = ;code = 32
char = i;code = 105
char = n;code = 110
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char = .;code = 46
char = <;code = 60
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char = C;code = 67
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char = O;code = 79
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char = l;code = 108
char = e;code = 101
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char = c;code = 99
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = s;code = 115
char = ;code = 32
char = i;code = 105
char = s;code = 115
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char = l;code = 108
char = o;code = 111
char = s;code = 115
char = e;code = 101
char = l;code = 108
char = y;code = 121
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = l;code = 108
char = a;code = 97
char = t;code = 116
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = t;code = 116
char = o;code = 111
char = ;code = 32
char = m;code = 109
char = e;code = 101
char = t;code = 116
char = a;code = 97
char = b;code = 98
char = o;code = 111
char = l;code = 108
char = i;code = 105
char = c;code = 99
char = ;code = 32
char = s;code = 115
char = y;code = 121
char = n;code = 110
char = d;code = 100
char = r;code = 114
char = o;code = 111
char = m;code = 109
char = e;code = 101
char = ,;code = 44
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = s;code = 115
char = u;code = 117
char = l;code = 108
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = s;code = 115
char = i;code = 105
char = s;code = 115
char = t;code = 116
char = a;code = 97
char = n;code = 110
char = c;code = 99
char = e;code = 101
char = ,;code = 44
char = ;code = 32
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char = n;code = 110
char = d;code = 100
char = ;code = 32
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result sql = OBJECTIVES : To investigate the prevalence of non-alcoholic fatty liver disease (NAFLD) in children and its relationship to metabolic syndrome, insulin resistance, and waist circumference (WC).

METHODS : This was a population-based cross-sectional, case-control study. Cases were selected among students of a primary and junior high school, respectively, and age- and sex-matched control subjects were selected randomly (ratio of cases to control subject was 37:113).

RESULTS : Of the 846 students, aged between 6 and 15 years, enrolled in the study and screened by ultrasonography, 37 children were diagnosed as having NAFLD (score >/= 1). There was a significant sex difference in the prevalence of NAFLD(P = 0.003). The trend test revealed a strong dose-response relationship (P < 0.001) between pediatric NAFLD and the number of the proposed components of pediatric metabolic syndrome in Japan (MetS-JC), such as a clustering of the components of MetS-JC. Additionally, the linear trend of the odds ratios (ORs) with increasing percentile of the homeostasis model assessment-insulin resistance (HOMA-IR) was statistically significant (P < 0.001). However, when WC was added to the logistic model, the ORs were no longer significant, whereas WC turned out to be an independent risk factor for NAFLD regardless of the HOMA-IR index.

CONCLUSION : The prevalence of NAFLD in children and adolescents is closely related to metabolic syndrome, insulin resistance, and WC.

Publication: Environ Health Prev Med 2009 Mar ;14(2)::142-9. :doi: 10.1007/s12199-008-0074-5.
Publication Date: 2009 Mar
Study Author(s): Tominaga, Kunihiko;Fujimoto, Edward;Suzuki, Keiko;Hayashi, Masayuki;Ichikawa, Masao;Inaba, Yutaka;
Institution: Department of Epidemiology and Environmental Health, Juntendo University School of Medicine, Juntendo University, Tokyo, Japan, [email protected]
Shortcut link to this study:
OBJECTIVES : To investigate the prevalence of non-alcoholic fatty liver disease (NAFLD) in children and its relationship to metabolic syndrome, insulin resistance, and waist circumference (WC).

METHODS : This was a population-based cross-sectional, case-control study. Cases were selected among students of a primary and junior high school, respectively, and age- and sex-matched control subjects were selected randomly (ratio of cases to control subject was 37:113).

RESULTS : Of the 846 students, aged between 6 and 15 years, enrolled in the study and screened by ultrasonography, 37 children were diagnosed as having NAFLD (score >/= 1). There was a significant sex difference in the prevalence of NAFLD(P = 0.003). The trend test revealed a strong dose-response relationship (P < 0.001) between pediatric NAFLD and the number of the proposed components of pediatric metabolic syndrome in Japan (MetS-JC), such as a clustering of the components of MetS-JC. Additionally, the linear trend of the odds ratios (ORs) with increasing percentile of the homeostasis model assessment-insulin resistance (HOMA-IR) was statistically significant (P < 0.001). However, when WC was added to the logistic model, the ORs were no longer significant, whereas WC turned out to be an independent risk factor for NAFLD regardless of the HOMA-IR index.

CONCLUSION : The prevalence of NAFLD in children and adolescents is closely related to metabolic syndrome, insulin resistance, and WC.
PMID: 19568858

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