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result sql = Factors associated with insulin resistance and non-alcoholic fatty liver disease among youths.
Factors associated with insulin resistance and non-alcoholic fatty liver disease among youths.
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char = l;code = 108
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char = s;code = 115
char = t;code = 116
char = s;code = 115
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char = S;code = 83
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char = r;code = 114
char = u;code = 117
char = m;code = 109
char = ;code = 32
char = l;code = 108
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char = i;code = 105
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char = s;code = 115
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char = o;code = 111
char = p;code = 112
char = r;code = 114
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char = n;code = 110
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char = k;code = 107
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char = r;code = 114
char = s;code = 115
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char = l;code = 108
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char = m;code = 109
char = a;code = 97
char = t;code = 116
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char = a;code = 97
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char = ;code = 32
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char = i;code = 105
char = v;code = 118
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char = t;code = 116
char = r;code = 114
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char = s;code = 115
char = s;code = 115
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char = a;code = 97
char = s;code = 115
char = ;code = 32
char = w;code = 119
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char = l;code = 108
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char = a;code = 97
char = s;code = 115
char = ;code = 32
char = t;code = 116
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char = e;code = 101
char = ;code = 32
char = C;code = 67
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char = M;code = 77
char = T;code = 84
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = n;code = 110
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char = r;code = 114
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char = a;code = 97
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char = w;code = 119
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char = i;code = 105
char = g;code = 103
char = h;code = 104
char = t;code = 116
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char = c;code = 99
char = h;code = 104
char = i;code = 105
char = l;code = 108
char = d;code = 100
char = r;code = 114
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char = h;code = 104
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char = m;code = 109
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char = t;code = 116
char = a;code = 97
char = b;code = 98
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char = i;code = 105
char = c;code = 99
char = ;code = 32
char = a;code = 97
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char = o;code = 111
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char = a;code = 97
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char = i;code = 105
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char = e;code = 101
char = r;code = 114
char = e;code = 101
char = ;code = 32
char = s;code = 115
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char = m;code = 109
char = i;code = 105
char = l;code = 108
char = a;code = 97
char = r;code = 114
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char = t;code = 116
char = o;code = 111
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char = o;code = 111
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char = s;code = 115
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char = c;code = 99
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char = i;code = 105
char = l;code = 108
char = d;code = 100
char = r;code = 114
char = e;code = 101
char = n;code = 110
char = .;code = 46
char = ;code = 32
char = C;code = 67
char = R;code = 82
char = F;code = 70
char = ;code = 32
char = h;code = 104
char = a;code = 97
char = d;code = 100
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = h;code = 104
char = i;code = 105
char = g;code = 103
char = h;code = 104
char = e;code = 101
char = s;code = 115
char = t;code = 116
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char = i;code = 105
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char = s;code = 115
char = e;code = 101
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char = o;code = 111
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char = r;code = 114
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char = l;code = 108
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = H;code = 72
char = O;code = 79
char = M;code = 77
char = A;code = 65
char = -;code = 45
char = I;code = 73
char = R;code = 82
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = A;code = 65
char = L;code = 76
char = T;code = 84
char = .;code = 46
char = ;code = 32
char = P;code = 80
char = h;code = 104
char = y;code = 121
char = s;code = 115
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char = c;code = 99
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char = ;code = 32
char = a;code = 97
char = c;code = 99
char = t;code = 116
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char = v;code = 118
char = i;code = 105
char = t;code = 116
char = y;code = 121
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char = ;code = 32
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char = e;code = 101
char = a;code = 97
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char = t;code = 116
char = h;code = 104
char = y;code = 121
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char = e;code = 101
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = n;code = 110
char = g;code = 103
char = ;code = 32
char = i;code = 105
char = n;code = 110
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char = e;code = 101
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char = ;code = 32
char = h;code = 104
char = a;code = 97
char = d;code = 100
char = ;code = 32
char = s;code = 115
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char = m;code = 109
char = i;code = 105
char = l;code = 108
char = a;code = 97
char = r;code = 114
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = v;code = 118
char = e;code = 101
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char = s;code = 115
char = e;code = 101
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char = c;code = 99
char = o;code = 111
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char = r;code = 114
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char = l;code = 108
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = H;code = 72
char = O;code = 79
char = M;code = 77
char = A;code = 65
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char = I;code = 73
char = R;code = 82
char = ;code = 32
char = a;code = 97
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char = d;code = 100
char = ;code = 32
char = A;code = 65
char = L;code = 76
char = T;code = 84
char = .;code = 46
char = ;code = 32
char = A;code = 65
char = p;code = 112
char = o;code = 111
char = B;code = 66
char = /;code = 47
char = A;code = 65
char = p;code = 112
char = o;code = 111
char = A;code = 65
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char = ;code = 32
char = h;code = 104
char = a;code = 97
char = d;code = 100
char = ;code = 32
char = s;code = 115
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char = g;code = 103
char = n;code = 110
char = i;code = 105
char = f;code = 102
char = i;code = 105
char = c;code = 99
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char = e;code = 101
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char = d;code = 100
char = e;code = 101
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char = t;code = 116
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char = s;code = 115
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char = i;code = 105
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char = p;code = 112
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char = s;code = 115
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char = f;code = 102
char = ;code = 32
char = H;code = 72
char = O;code = 79
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char = A;code = 65
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char = I;code = 73
char = R;code = 82
char = ;code = 32
char = a;code = 97
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char = d;code = 100
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char = A;code = 65
char = L;code = 76
char = T;code = 84
char = .;code = 46
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char = W;code = 87
char = a;code = 97
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char = s;code = 115
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char = /;code = 47
char = A;code = 65
char = p;code = 112
char = o;code = 111
char = A;code = 65
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char = I;code = 73
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char = a;code = 97
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char = i;code = 105
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char = h;code = 104
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char = i;code = 105
char = o;code = 111
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char = i;code = 105
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char = ;code = 32
char = i;code = 105
char = n;code = 110
char = c;code = 99
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char = a;code = 97
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char = r;code = 114
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char = s;code = 115
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char = o;code = 111
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char = s;code = 115
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char = s;code = 115
char = t;code = 116
char = a;code = 97
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char = c;code = 99
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char = ;code = 32
char = a;code = 97
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char = d;code = 100
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char = N;code = 78
char = A;code = 65
char = F;code = 70
char = L;code = 76
char = D;code = 68
char = ,;code = 44
char = ;code = 32
char = w;code = 119
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char = e;code = 101
char = r;code = 114
char = e;code = 101
char = a;code = 97
char = s;code = 115
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char = C;code = 67
char = R;code = 82
char = F;code = 70
char = ;code = 32
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char = o;code = 111
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char = l;code = 108
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char = y;code = 121
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char = a;code = 97
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char = e;code = 101
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char = s;code = 115
char = k;code = 107
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char = s;code = 115
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char = f;code = 102
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char = T;code = 84
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char = a;code = 97
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char = s;code = 115
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char = N;code = 78
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char = L;code = 76
char = D;code = 68
char = .;code = 46
char = <;code = 60
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char = >;code = 62
char = <;code = 60
char = b;code = 98
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char = C;code = 67
char = O;code = 79
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char = C;code = 67
char = L;code = 76
char = U;code = 85
char = S;code = 83
char = I;code = 73
char = O;code = 79
char = N;code = 78
char = S;code = 83
char = ;code = 32
char = :;code = 58
char = ;code = 32
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char = /;code = 47
char = b;code = 98
char = >;code = 62
char = W;code = 87
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char = f;code = 102
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char = s;code = 115
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char = f;code = 102
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char = t;code = 116
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char = s;code = 115
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char = b;code = 98
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char = t;code = 116
char = w;code = 119
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char = u;code = 117
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char = i;code = 105
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char = r;code = 114
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char = s;code = 115
char = i;code = 105
char = s;code = 115
char = t;code = 116
char = a;code = 97
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char = c;code = 99
char = e;code = 101
char = ;code = 32
char = a;code = 97
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char = d;code = 100
char = ;code = 32
char = N;code = 78
char = A;code = 65
char = F;code = 70
char = L;code = 76
char = D;code = 68
char = ,;code = 44
char = ;code = 32
char = a;code = 97
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char = s;code = 115
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char = m;code = 109
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char = l;code = 108
char = a;code = 97
char = r;code = 114
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char = r;code = 114
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char = s;code = 115
char = k;code = 107
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char = f;code = 102
char = a;code = 97
char = c;code = 99
char = t;code = 116
char = o;code = 111
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char = s;code = 115
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char = a;code = 97
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char = d;code = 100
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char = p;code = 112
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char = o;code = 111
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char = e;code = 101
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char = v;code = 118
char = e;code = 101
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char = f;code = 102
char = a;code = 97
char = c;code = 99
char = t;code = 116
char = o;code = 111
char = r;code = 114
char = s;code = 115
char = ;code = 32
char = f;code = 102
char = o;code = 111
char = r;code = 114
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char = t;code = 116
char = h;code = 104
char = e;code = 101
char = s;code = 115
char = e;code = 101
char = ;code = 32
char = t;code = 116
char = w;code = 119
char = o;code = 111
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char = i;code = 105
char = n;code = 110
char = t;code = 116
char = e;code = 101
char = r;code = 114
char = -;code = 45
char = r;code = 114
char = e;code = 101
char = l;code = 108
char = a;code = 97
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char = e;code = 101
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char = d;code = 100
char = i;code = 105
char = s;code = 115
char = o;code = 111
char = r;code = 114
char = d;code = 100
char = e;code = 101
char = r;code = 114
char = s;code = 115
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result sql = OBJECTIVES : To compare the cardio-metabolic risk factors, fitness and lifestyle among adolescents with and without weight disorders and/or metabolic abnormality, and to identify the factors associated with insulin resistance and non-alcoholic fatty liver disease (NAFLD) in this age group.

METHODS : This cross-sectional study comprised 100 adolescents (12-18 years) consisting of four subgroups of normal weight/obese with and without components of the metabolic syndrome. Fasting blood glucose, insulin, lipid profile, apolipoproteins A, B, CRP, oxidized-LDL, malondialdehyde and alanine aminotransferase (ALT) were examined. Cardiorespiratory fitness (CRF) and the sonographic findings of liver and carotid intima media thickness were determined.

RESULTS : Overall 95 participants completed all tests. Serum lipids, lipoproteins, the markers of inflammation and oxidative stress as well as the C-IMT of normal weight children with a metabolic abnormality were similar to obese children. CRF had the highest inverse correlation with HOMA-IR and ALT. Physical activity and healthy eating index had similar inverse correlation with HOMA-IR and ALT. ApoB/ApoA-I had significant independent association with upper quartiles of HOMA-IR and ALT. Waist circumference and ApoB/ApoA-I ratio had the highest odds ratio in increasing the risk of insulin resistance and NAFLD, whereas CRF followed by healthy eating index decreased this risk significantly. C-IMT was significantly associated with insulin resistance and NAFLD.

CONCLUSIONS : We found significant associations between insulin resistance and NAFLD, and similar risk factors and protective factors for these two inter-related disorders; in this regard the role of CRF and apolipoprotein B to apolipoprotein A-I (ApoB/ApoA-I) ratio in the pediatric age group is underscored.

Publication: Atherosclerosis 2009 Jun ;204(2)::538-43. :doi: 10.1016/j.atherosclerosis.2008.09.034.
Publication Date: 2009 Jun
Study Author(s): Kelishadi, Roya;Cook, Stephen R;Amra, Babak;Adibi, Atoosa;
Institution: Pediatric Preventive Cardiology Department, Isfahan Cardiovascular Research Centre, Isfahan University of Medical Sciences, P.O. Box 81465-1148, Isfahan, Iran. [email protected]
Shortcut link to this study:
OBJECTIVES : To compare the cardio-metabolic risk factors, fitness and lifestyle among adolescents with and without weight disorders and/or metabolic abnormality, and to identify the factors associated with insulin resistance and non-alcoholic fatty liver disease (NAFLD) in this age group.

METHODS : This cross-sectional study comprised 100 adolescents (12-18 years) consisting of four subgroups of normal weight/obese with and without components of the metabolic syndrome. Fasting blood glucose, insulin, lipid profile, apolipoproteins A, B, CRP, oxidized-LDL, malondialdehyde and alanine aminotransferase (ALT) were examined. Cardiorespiratory fitness (CRF) and the sonographic findings of liver and carotid intima media thickness were determined.

RESULTS : Overall 95 participants completed all tests. Serum lipids, lipoproteins, the markers of inflammation and oxidative stress as well as the C-IMT of normal weight children with a metabolic abnormality were similar to obese children. CRF had the highest inverse correlation with HOMA-IR and ALT. Physical activity and healthy eating index had similar inverse correlation with HOMA-IR and ALT. ApoB/ApoA-I had significant independent association with upper quartiles of HOMA-IR and ALT. Waist circumference and ApoB/ApoA-I ratio had the highest odds ratio in increasing the risk of insulin resistance and NAFLD, whereas CRF followed by healthy eating index decreased this risk significantly. C-IMT was significantly associated with insulin resistance and NAFLD.

CONCLUSIONS : We found significant associations between insulin resistance and NAFLD, and similar risk factors and protective factors for these two inter-related disorders; in this regard the role of CRF and apolipoprotein B to apolipoprotein A-I (ApoB/ApoA-I) ratio in the pediatric age group is underscored.
PMID: 19013572

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