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char = 2;code = 50
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char = i;code = 105
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char = b;code = 98
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char = i;code = 105
char = c;code = 99
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char = z;code = 122
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char = d;code = 100
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char = n;code = 110
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char = l;code = 108
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char = W;code = 87
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char = a;code = 97
char = r;code = 114
char = ;code = 32
char = r;code = 114
char = a;code = 97
char = t;code = 116
char = s;code = 115
char = .;code = 46
result sql = Hypoglycemic effect of Chlorella vulgaris intake in type 2 diabetic Goto-Kakizaki and normal Wistar rats.
Hypoglycemic effect of Chlorella vulgaris intake in type 2 diabetic Goto-Kakizaki and normal Wistar rats.
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char = e;code = 101
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char = W;code = 87
char = i;code = 105
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char = a;code = 97
char = r;code = 114
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char = o;code = 111
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char = e;code = 101
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char = r;code = 114
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char = ;code = 32
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char = s;code = 115
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char = r;code = 114
char = -;code = 45
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char = h;code = 104
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char = l;code = 108
char = l;code = 108
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char = ;code = 32
char = g;code = 103
char = r;code = 114
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char = u;code = 117
char = p;code = 112
char = s;code = 115
char = .;code = 46
char = ;code = 32
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char = ;code = 32
char = c;code = 99
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char = c;code = 99
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char = o;code = 111
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char = c;code = 99
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char = e;code = 101
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char = t;code = 116
char = e;code = 101
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char = o;code = 111
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char = ;code = 32
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char = f;code = 102
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char = i;code = 105
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char = i;code = 105
char = n;code = 110
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char = e;code = 101
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char = i;code = 105
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char = i;code = 105
char = v;code = 118
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char = y;code = 121
char = ;code = 32
char = i;code = 105
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char = y;code = 121
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char = b;code = 98
char = e;code = 101
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char = ;code = 32
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char = n;code = 110
char = o;code = 111
char = r;code = 114
char = m;code = 109
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char = l;code = 108
char = ;code = 32
char = W;code = 87
char = i;code = 105
char = s;code = 115
char = t;code = 116
char = a;code = 97
char = r;code = 114
char = ;code = 32
char = r;code = 114
char = a;code = 97
char = t;code = 116
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result sql = The aim of this study was to examine the hypoglycemic effect of chlorella in 6 week-old type 2 diabetic Goto-Kakizaki (GK, n=30) rats and 6 week-old normal Wistar (n=30) rats. Animals were randomly assigned to 3 groups respectively, and were fed three different experimental diets containing 0%, 3% or 5% (w/w) chlorella for 8 weeks. In diabetic GK rats, the insulinogenic-indices were not significantly different among the groups. The concentrations of fasting plasma glucagon and hepatic triglyceride, and the insulin/glucagon ratios of the GK-3% chlorella and GK-5% chlorella groups were significantly lower than those of the GK-control group. The HOMA-index and the concentrations of fasting blood glucose and plasma insulin of the GK-3% chlorella and GK-5% chlorella groups were slightly lower than those of the GK-control group. In normal Wistar rats, the insulinogenic-indices were not significantly different among the normal groups, but that of the Wistar-5% chlorella group was slightly higher than the other groups. The concentrations of fasting blood glucose and plasma insulin, and the HOMA-index of the Wistar-5% chlorella group were a little higher, and the fasting plasma glucagon concentration and the insulin/glucagon ratio of the Wistar-5% chlorella group were significantly higher than those of the Wistar-control and Wistar-3% chlorella groups. In conclusion, this study shows that the glucose-stimulated insulin secretion was not affected by the intake of chlorella, which could be beneficial, however, in improving insulin sensitivity in type 2 diabetic GK and normal Wistar rats.

Publication: Nutr Res Pract 2009 Spring ;3(1)::23-30. :doi: 10.4162/nrp.2009.3.1.23.
Publication Date: 2009 Spring
Study Author(s): Jeong, Hyejin;Kwon, Hye Jin;Kim, Mi Kyung;
Institution: Department of Nutritional Science and Food Management, Ewha Womans University, 11-1 Daehyeon-dong, Seodaemun-gu, Seoul 120-750, Korea.
Shortcut link to this study:
The aim of this study was to examine the hypoglycemic effect of chlorella in 6 week-old type 2 diabetic Goto-Kakizaki (GK, n=30) rats and 6 week-old normal Wistar (n=30) rats. Animals were randomly assigned to 3 groups respectively, and were fed three different experimental diets containing 0%, 3% or 5% (w/w) chlorella for 8 weeks. In diabetic GK rats, the insulinogenic-indices were not significantly different among the groups. The concentrations of fasting plasma glucagon and hepatic triglyceride, and the insulin/glucagon ratios of the GK-3% chlorella and GK-5% chlorella groups were significantly lower than those of the GK-control group. The HOMA-index and the concentrations of fasting blood glucose and plasma insulin of the GK-3% chlorella and GK-5% chlorella groups were slightly lower than those of the GK-control group. In normal Wistar rats, the insulinogenic-indices were not significantly different among the normal groups, but that of the Wistar-5% chlorella group was slightly higher than the other groups. The concentrations of fasting blood glucose and plasma insulin, and the HOMA-index of the Wistar-5% chlorella group were a little higher, and the fasting plasma glucagon concentration and the insulin/glucagon ratio of the Wistar-5% chlorella group were significantly higher than those of the Wistar-control and Wistar-3% chlorella groups. In conclusion, this study shows that the glucose-stimulated insulin secretion was not affected by the intake of chlorella, which could be beneficial, however, in improving insulin sensitivity in type 2 diabetic GK and normal Wistar rats.
PMID: 20016698

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