char = V;code = 86 char = i;code = 105 char = t;code = 116 char = a;code = 97 char = m;code = 109 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = D;code = 68 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = c;code = 99 char = e;code = 101 char = p;code = 112 char = t;code = 116 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = p;code = 112 char = o;code = 111 char = l;code = 108 char = y;code = 121 char = m;code = 109 char = o;code = 111 char = r;code = 114 char = p;code = 112 char = h;code = 104 char = i;code = 105 char = s;code = 115 char = m;code = 109 char = s;code = 115 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = b;code = 98 char = r;code = 114 char = e;code = 101 char = a;code = 97 char = s;code = 115 char = t;code = 116 char = ;code = 32 char = c;code = 99 char = a;code = 97 char = n;code = 110 char = c;code = 99 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = r;code = 114 char = i;code = 105 char = s;code = 115 char = k;code = 107 char = :;code = 58 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = s;code = 115 char = u;code = 117 char = l;code = 108 char = t;code = 116 char = s;code = 115 char = ;code = 32 char = f;code = 102 char = r;code = 114 char = o;code = 111 char = m;code = 109 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = N;code = 78 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = C;code = 67 char = a;code = 97 char = n;code = 110 char = c;code = 99 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = I;code = 73 char = n;code = 110 char = s;code = 115 char = t;code = 116 char = i;code = 105 char = t;code = 116 char = u;code = 117 char = t;code = 116 char = e;code = 101 char = ;code = 32 char = B;code = 66 char = r;code = 114 char = e;code = 101 char = a;code = 97 char = s;code = 115 char = t;code = 116 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = P;code = 80 char = r;code = 114 char = o;code = 111 char = s;code = 115 char = t;code = 116 char = a;code = 97 char = t;code = 116 char = e;code = 101 char = ;code = 32 char = C;code = 67 char = a;code = 97 char = n;code = 110 char = c;code = 99 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = C;code = 67 char = o;code = 111 char = h;code = 104 char = o;code = 111 char = r;code = 114 char = t;code = 116 char = ;code = 32 char = C;code = 67 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = o;code = 111 char = r;code = 114 char = t;code = 116 char = i;code = 105 char = u;code = 117 char = m;code = 109 char = .;code = 46 result sql = Vitamin D receptor polymorphisms and breast cancer risk: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium.
Vitamin D receptor polymorphisms and breast cancer risk: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium.char = <;code = 60 char = b;code = 98 char = >;code = 62 char = B;code = 66 char = A;code = 65 char = C;code = 67 char = K;code = 75 char = G;code = 71 char = R;code = 82 char = O;code = 79 char = U;code = 85 char = N;code = 78 char = D;code = 68 char = ;code = 32 char = :;code = 58 char = ;code = 32 char = <;code = 60 char = /;code = 47 char = b;code = 98 char = >;code = 62 char = V;code = 86 char = i;code = 105 char = t;code = 116 char = a;code = 97 char = m;code = 109 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = D;code = 68 char = ;code = 32 char = i;code = 105 char = s;code = 115 char = ;code = 32 char = h;code = 104 char = y;code = 121 char = p;code = 112 char = o;code = 111 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = s;code = 115 char = i;code = 105 char = z;code = 122 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = t;code = 116 char = o;code = 111 char = ;code = 32 char = l;code = 108 char = o;code = 111 char = w;code = 119 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = r;code = 114 char = i;code = 105 char = s;code = 115 char = k;code = 107 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = b;code = 98 char = r;code = 114 char = e;code = 101 char = a;code = 97 char = s;code = 115 char = t;code = 116 char = ;code = 32 char = c;code = 99 char = a;code = 97 char = n;code = 110 char = c;code = 99 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = b;code = 98 char = y;code = 121 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = h;code = 104 char = i;code = 105 char = b;code = 98 char = i;code = 105 char = t;code = 116 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = ;code = 32 char = c;code = 99 char = e;code = 101 char = l;code = 108 char = l;code = 108 char = ;code = 32 char = p;code = 112 char = r;code = 114 char = o;code = 111 char = l;code = 108 char = i;code = 105 char = f;code = 102 char = e;code = 101 char = r;code = 114 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = v;code = 118 char = i;code = 105 char = a;code = 97 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = n;code = 110 char = u;code = 117 char = c;code = 99 char = l;code = 108 char = e;code = 101 char = a;code = 97 char = r;code = 114 char = ;code = 32 char = v;code = 118 char = i;code = 105 char = t;code = 116 char = a;code = 97 char = m;code = 109 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = D;code = 68 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = c;code = 99 char = e;code = 101 char = p;code = 112 char = t;code = 116 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = (;code = 40 char = V;code = 86 char = D;code = 68 char = R;code = 82 char = );code = 41 char = .;code = 46 char = ;code = 32 char = T;code = 84 char = w;code = 119 char = o;code = 111 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = m;code = 109 char = m;code = 109 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = s;code = 115 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = l;code = 108 char = e;code = 101 char = ;code = 32 char = n;code = 110 char = u;code = 117 char = c;code = 99 char = l;code = 108 char = e;code = 101 char = o;code = 111 char = t;code = 116 char = i;code = 105 char = d;code = 100 char = e;code = 101 char = ;code = 32 char = p;code = 112 char = o;code = 111 char = l;code = 108 char = y;code = 121 char = m;code = 109 char = o;code = 111 char = r;code = 114 char = p;code = 112 char = h;code = 104 char = i;code = 105 char = s;code = 115 char = m;code = 109 char = s;code = 115 char = ;code = 32 char = (;code = 40 char = S;code = 83 char = N;code = 78 char = P;code = 80 char = );code = 41 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = V;code = 86 char = D;code = 68 char = R;code = 82 char = ;code = 32 char = g;code = 103 char = e;code = 101 char = n;code = 110 char = e;code = 101 char = ;code = 32 char = (;code = 40 char = V;code = 86 char = D;code = 68 char = R;code = 82 char = );code = 41 char = ,;code = 44 char = ;code = 32 char = r;code = 114 char = s;code = 115 char = 1;code = 49 char = 5;code = 53 char = 4;code = 52 char = 4;code = 52 char = 4;code = 52 char = 1;code = 49 char = 0;code = 48 char = ;code = 32 char = (;code = 40 char = B;code = 66 char = s;code = 115 char = m;code = 109 char = I;code = 73 char = );code = 41 char = ,;code = 44 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = r;code = 114 char = s;code = 115 char = 2;code = 50 char = 2;code = 50 char = 2;code = 50 char = 8;code = 56 char = 5;code = 53 char = 7;code = 55 char = 0;code = 48 char = ;code = 32 char = (;code = 40 char = F;code = 70 char = o;code = 111 char = k;code = 107 char = I;code = 73 char = );code = 41 char = ,;code = 44 char = ;code = 32 char = h;code = 104 char = a;code = 97 char = v;code = 118 char = e;code = 101 char = ;code = 32 char = b;code = 98 char = e;code = 101 char = e;code = 101 char = n;code = 110 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = i;code = 105 char = s;code = 115 char = t;code = 116 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = l;code = 108 char = y;code = 121 char = ;code = 32 char = a;code = 97 char = s;code = 115 char = s;code = 115 char = o;code = 111 char = c;code = 99 char = i;code = 105 char = a;code = 97 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = w;code = 119 char = i;code = 105 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = b;code = 98 char = r;code = 114 char = e;code = 101 char = a;code = 97 char = s;code = 115 char = t;code = 116 char = ;code = 32 char = c;code = 99 char = a;code = 97 char = n;code = 110 char = c;code = 99 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = r;code = 114 char = i;code = 105 char = s;code = 115 char = k;code = 107 char = .;code = 46 char = ;code = 32 char = I;code = 73 char = n;code = 110 char = c;code = 99 char = r;code = 114 char = e;code = 101 char = a;code = 97 char = s;code = 115 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = r;code = 114 char = i;code = 105 char = s;code = 115 char = k;code = 107 char = ;code = 32 char = h;code = 104 char = a;code = 97 char = s;code = 115 char = ;code = 32 char = b;code = 98 char = e;code = 101 char = e;code = 101 char = n;code = 110 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = p;code = 112 char = o;code = 111 char = r;code = 114 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = f;code = 102 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = F;code = 70 char = o;code = 111 char = k;code = 107 char = I;code = 73 char = ;code = 32 char = f;code = 102 char = f;code = 102 char = ;code = 32 char = g;code = 103 char = e;code = 101 char = n;code = 110 char = o;code = 111 char = t;code = 116 char = y;code = 121 char = p;code = 112 char = e;code = 101 char = ,;code = 44 char = ;code = 32 char = w;code = 119 char = h;code = 104 char = i;code = 105 char = c;code = 99 char = h;code = 104 char = ;code = 32 char = e;code = 101 char = n;code = 110 char = c;code = 99 char = o;code = 111 char = d;code = 100 char = e;code = 101 char = s;code = 115 char = ;code = 32 char = a;code = 97 char = ;code = 32 char = l;code = 108 char = e;code = 101 char = s;code = 115 char = s;code = 115 char = ;code = 32 char = t;code = 116 char = r;code = 114 char = a;code = 97 char = n;code = 110 char = s;code = 115 char = c;code = 99 char = r;code = 114 char = i;code = 105 char = p;code = 112 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = a;code = 97 char = l;code = 108 char = l;code = 108 char = y;code = 121 char = ;code = 32 char = a;code = 97 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = e;code = 101 char = ;code = 32 char = i;code = 105 char = s;code = 115 char = o;code = 111 char = f;code = 102 char = o;code = 111 char = r;code = 114 char = m;code = 109 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = V;code = 86 char = D;code = 68 char = R;code = 82 char = ,;code = 44 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = d;code = 100 char = u;code = 117 char = c;code = 99 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = r;code = 114 char = i;code = 105 char = s;code = 115 char = k;code = 107 char = ;code = 32 char = h;code = 104 char = a;code = 97 char = s;code = 115 char = ;code = 32 char = b;code = 98 char = e;code = 101 char = e;code = 101 char = n;code = 110 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = p;code = 112 char = o;code = 111 char = r;code = 114 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = f;code = 102 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = B;code = 66 char = s;code = 115 char = m;code = 109 char = I;code = 73 char = ;code = 32 char = B;code = 66 char = B;code = 66 char = ;code = 32 char = g;code = 103 char = e;code = 101 char = n;code = 110 char = o;code = 111 char = t;code = 116 char = y;code = 121 char = p;code = 112 char = e;code = 101 char = ,;code = 44 char = ;code = 32 char = a;code = 97 char = ;code = 32 char = S;code = 83 char = N;code = 78 char = P;code = 80 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = s;code = 115 char = t;code = 116 char = r;code = 114 char = o;code = 111 char = n;code = 110 char = g;code = 103 char = ;code = 32 char = l;code = 108 char = i;code = 105 char = n;code = 110 char = k;code = 107 char = a;code = 97 char = g;code = 103 char = e;code = 101 char = ;code = 32 char = d;code = 100 char = i;code = 105 char = s;code = 115 char = e;code = 101 char = q;code = 113 char = u;code = 117 char = i;code = 105 char = l;code = 108 char = i;code = 105 char = b;code = 98 char = r;code = 114 char = i;code = 105 char = u;code = 117 char = m;code = 109 char = ;code = 32 char = w;code = 119 char = i;code = 105 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = a;code = 97 char = ;code = 32 char = 3;code = 51 char = ';code = 39 char = -;code = 45 char = u;code = 117 char = n;code = 110 char = t;code = 116 char = r;code = 114 char = a;code = 97 char = n;code = 110 char = s;code = 115 char = l;code = 108 char = a;code = 97 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = g;code = 103 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ,;code = 44 char = ;code = 32 char = w;code = 119 char = h;code = 104 char = i;code = 105 char = c;code = 99 char = h;code = 104 char = ;code = 32 char = m;code = 109 char = a;code = 97 char = y;code = 121 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = f;code = 102 char = l;code = 108 char = u;code = 117 char = e;code = 101 char = n;code = 110 char = c;code = 99 char = e;code = 101 char = ;code = 32 char = V;code = 86 char = D;code = 68 char = R;code = 82 char = ;code = 32 char = m;code = 109 char = R;code = 82 char = N;code = 78 char = A;code = 65 char = ;code = 32 char = s;code = 115 char = t;code = 116 char = a;code = 97 char = b;code = 98 char = i;code = 105 char = l;code = 108 char = i;code = 105 char = t;code = 116 char = y;code = 121 char = .;code = 46 char = <;code = 60 char = b;code = 98 char = r;code = 114 char = /;code = 47 char = >;code = 62 char = <;code = 60 char = b;code = 98 char = r;code = 114 char = /;code = 47 char = >;code = 62 char = <;code = 60 char = b;code = 98 char = >;code = 62 char = M;code = 77 char = E;code = 69 char = T;code = 84 char = H;code = 72 char = O;code = 79 char = D;code = 68 char = S;code = 83 char = ;code = 32 char = :;code = 58 char = ;code = 32 char = <;code = 60 char = /;code = 47 char = b;code = 98 char = >;code = 62 char = W;code = 87 char = e;code = 101 char = ;code = 32 char = p;code = 112 char = o;code = 111 char = o;code = 111 char = l;code = 108 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = d;code = 100 char = a;code = 97 char = t;code = 116 char = a;code = 97 char = ;code = 32 char = f;code = 102 char = r;code = 114 char = o;code = 111 char = m;code = 109 char = ;code = 32 char = 6;code = 54 char = ;code = 32 char = p;code = 112 char = r;code = 114 char = o;code = 111 char = s;code = 115 char = p;code = 112 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = e;code = 101 char = ;code = 32 char = s;code = 115 char = t;code = 116 char = u;code = 117 char = d;code = 100 char = i;code = 105 char = e;code = 101 char = s;code = 115 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = N;code = 78 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = C;code = 67 char = a;code = 97 char = n;code = 110 char = c;code = 99 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = I;code = 73 char = n;code = 110 char = s;code = 115 char = t;code = 116 char = i;code = 105 char = t;code = 116 char = u;code = 117 char = t;code = 116 char = e;code = 101 char = ;code = 32 char = B;code = 66 char = r;code = 114 char = e;code = 101 char = a;code = 97 char = s;code = 115 char = t;code = 116 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = P;code = 80 char = r;code = 114 char = o;code = 111 char = s;code = 115 char = t;code = 116 char = a;code = 97 char = t;code = 116 char = e;code = 101 char = ;code = 32 char = C;code = 67 char = a;code = 97 char = n;code = 110 char = c;code = 99 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = C;code = 67 char = o;code = 111 char = h;code = 104 char = o;code = 111 char = r;code = 114 char = t;code = 116 char = ;code = 32 char = C;code = 67 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = o;code = 111 char = r;code = 114 char = t;code = 116 char = i;code = 105 char = u;code = 117 char = m;code = 109 char = ;code = 32 char = t;code = 116 char = o;code = 111 char = ;code = 32 char = e;code = 101 char = x;code = 120 char = a;code = 97 char = m;code = 109 char = i;code = 105 char = n;code = 110 char = e;code = 101 char = ;code = 32 char = a;code = 97 char = s;code = 115 char = s;code = 115 char = o;code = 111 char = c;code = 99 char = i;code = 105 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = ;code = 32 char = b;code = 98 char = e;code = 101 char = t;code = 116 char = w;code = 119 char = e;code = 101 char = e;code = 101 char = n;code = 110 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = s;code = 115 char = e;code = 101 char = ;code = 32 char = S;code = 83 char = N;code = 78 char = P;code = 80 char = s;code = 115 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = b;code = 98 char = r;code = 114 char = e;code = 101 char = a;code = 97 char = s;code = 115 char = t;code = 116 char = ;code = 32 char = c;code = 99 char = a;code = 97 char = n;code = 110 char = c;code = 99 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = a;code = 97 char = m;code = 109 char = o;code = 111 char = n;code = 110 char = g;code = 103 char = ;code = 32 char = >;code = 62 char = 6;code = 54 char = ,;code = 44 char = 3;code = 51 char = 0;code = 48 char = 0;code = 48 char = ;code = 32 char = c;code = 99 char = a;code = 97 char = s;code = 115 char = e;code = 101 char = s;code = 115 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = 8;code = 56 char = ,;code = 44 char = 1;code = 49 char = 0;code = 48 char = 0;code = 48 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = t;code = 116 char = r;code = 114 char = o;code = 111 char = l;code = 108 char = s;code = 115 char = ;code = 32 char = f;code = 102 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = e;code = 101 char = a;code = 97 char = c;code = 99 char = h;code = 104 char = ;code = 32 char = S;code = 83 char = N;code = 78 char = P;code = 80 char = ;code = 32 char = u;code = 117 char = s;code = 115 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = d;code = 100 char = i;code = 105 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = l;code = 108 char = o;code = 111 char = g;code = 103 char = i;code = 105 char = s;code = 115 char = t;code = 116 char = i;code = 105 char = c;code = 99 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = g;code = 103 char = r;code = 114 char = e;code = 101 char = s;code = 115 char = s;code = 115 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = .;code = 46 char = <;code = 60 char = b;code = 98 char = r;code = 114 char = /;code = 47 char = >;code = 62 char = <;code = 60 char = b;code = 98 char = r;code = 114 char = /;code = 47 char = >;code = 62 char = <;code = 60 char = b;code = 98 char = >;code = 62 char = R;code = 82 char = E;code = 69 char = S;code = 83 char = U;code = 85 char = L;code = 76 char = T;code = 84 char = S;code = 83 char = ;code = 32 char = :;code = 58 char = ;code = 32 char = <;code = 60 char = /;code = 47 char = b;code = 98 char = >;code = 62 char = T;code = 84 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = o;code = 111 char = d;code = 100 char = d;code = 100 char = s;code = 115 char = ;code = 32 char = r;code = 114 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = ;code = 32 char = (;code = 40 char = O;code = 79 char = R;code = 82 char = );code = 41 char = ;code = 32 char = f;code = 102 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = r;code = 114 char = s;code = 115 char = 2;code = 50 char = 2;code = 50 char = 2;code = 50 char = 8;code = 56 char = 5;code = 53 char = 7;code = 55 char = 0;code = 48 char = ;code = 32 char = (;code = 40 char = F;code = 70 char = o;code = 111 char = k;code = 107 char = I;code = 73 char = );code = 41 char = ;code = 32 char = f;code = 102 char = f;code = 102 char = ;code = 32 char = v;code = 118 char = e;code = 101 char = r;code = 114 char = s;code = 115 char = u;code = 117 char = s;code = 115 char = ;code = 32 char = F;code = 70 char = F;code = 70 char = ;code = 32 char = g;code = 103 char = e;code = 101 char = n;code = 110 char = o;code = 111 char = t;code = 116 char = y;code = 121 char = p;code = 112 char = e;code = 101 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = o;code = 111 char = v;code = 118 char = e;code = 101 char = r;code = 114 char = a;code = 97 char = l;code = 108 char = l;code = 108 char = ;code = 32 char = p;code = 112 char = o;code = 111 char = p;code = 112 char = u;code = 117 char = l;code = 108 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = w;code = 119 char = a;code = 97 char = s;code = 115 char = ;code = 32 char = s;code = 115 char = t;code = 116 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = s;code = 115 char = t;code = 116 char = i;code = 105 char = c;code = 99 char = a;code = 97 char = l;code = 108 char = l;code = 108 char = y;code = 121 char = ;code = 32 char = s;code = 115 char = i;code = 105 char = g;code = 103 char = n;code = 110 char = i;code = 105 char = f;code = 102 char = i;code = 105 char = c;code = 99 char = a;code = 97 char = n;code = 110 char = t;code = 116 char = l;code = 108 char = y;code = 121 char = ;code = 32 char = e;code = 101 char = l;code = 108 char = e;code = 101 char = v;code = 118 char = a;code = 97 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = [;code = 91 char = O;code = 79 char = R;code = 82 char = ,;code = 44 char = ;code = 32 char = 1;code = 49 char = .;code = 46 char = 1;code = 49 char = 6;code = 54 char = ;;code = 59 char = ;code = 32 char = 9;code = 57 char = 5;code = 53 char = %;code = 37 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = f;code = 102 char = i;code = 105 char = d;code = 100 char = e;code = 101 char = n;code = 110 char = c;code = 99 char = e;code = 101 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = t;code = 116 char = e;code = 101 char = r;code = 114 char = v;code = 118 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = (;code = 40 char = 9;code = 57 char = 5;code = 53 char = %;code = 37 char = ;code = 32 char = C;code = 67 char = I;code = 73 char = );code = 41 char = ,;code = 44 char = ;code = 32 char = 1;code = 49 char = .;code = 46 char = 0;code = 48 char = 4;code = 52 char = -;code = 45 char = 1;code = 49 char = .;code = 46 char = 2;code = 50 char = 8;code = 56 char = ];code = 93 char = ;code = 32 char = b;code = 98 char = u;code = 117 char = t;code = 116 char = ;code = 32 char = w;code = 119 char = a;code = 97 char = s;code = 115 char = ;code = 32 char = w;code = 119 char = e;code = 101 char = a;code = 97 char = k;code = 107 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = o;code = 111 char = n;code = 110 char = c;code = 99 char = e;code = 101 char = ;code = 32 char = d;code = 100 char = a;code = 97 char = t;code = 116 char = a;code = 97 char = ;code = 32 char = f;code = 102 char = r;code = 114 char = o;code = 111 char = m;code = 109 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = h;code = 104 char = o;code = 111 char = r;code = 114 char = t;code = 116 char = ;code = 32 char = w;code = 119 char = i;code = 105 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = p;code = 112 char = r;code = 114 char = e;code = 101 char = v;code = 118 char = i;code = 105 char = o;code = 111 char = u;code = 117 char = s;code = 115 char = l;code = 108 char = y;code = 121 char = ;code = 32 char = p;code = 112 char = u;code = 117 char = b;code = 98 char = l;code = 108 char = i;code = 105 char = s;code = 115 char = h;code = 104 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = p;code = 112 char = o;code = 111 char = s;code = 115 char = i;code = 105 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = e;code = 101 char = ;code = 32 char = f;code = 102 char = i;code = 105 char = n;code = 110 char = d;code = 100 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = s;code = 115 char = ;code = 32 char = w;code = 119 char = e;code = 101 char = r;code = 114 char = e;code = 101 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = m;code = 109 char = o;code = 111 char = v;code = 118 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = (;code = 40 char = O;code = 79 char = R;code = 82 char = ,;code = 44 char = ;code = 32 char = 1;code = 49 char = .;code = 46 char = 1;code = 49 char = 0;code = 48 char = ;;code = 59 char = ;code = 32 char = 9;code = 57 char = 5;code = 53 char = %;code = 37 char = ;code = 32 char = C;code = 67 char = I;code = 73 char = ,;code = 44 char = ;code = 32 char = 0;code = 48 char = .;code = 46 char = 9;code = 57 char = 8;code = 56 char = -;code = 45 char = 1;code = 49 char = .;code = 46 char = 2;code = 50 char = 4;code = 52 char = );code = 41 char = .;code = 46 char = ;code = 32 char = N;code = 78 char = o;code = 111 char = ;code = 32 char = a;code = 97 char = s;code = 115 char = s;code = 115 char = o;code = 111 char = c;code = 99 char = i;code = 105 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = w;code = 119 char = a;code = 97 char = s;code = 115 char = ;code = 32 char = n;code = 110 char = o;code = 111 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = b;code = 98 char = e;code = 101 char = t;code = 116 char = w;code = 119 char = e;code = 101 char = e;code = 101 char = n;code = 110 char = ;code = 32 char = r;code = 114 char = s;code = 115 char = 1;code = 49 char = 5;code = 53 char = 4;code = 52 char = 4;code = 52 char = 4;code = 52 char = 1;code = 49 char = 0;code = 48 char = ;code = 32 char = (;code = 40 char = B;code = 66 char = s;code = 115 char = m;code = 109 char = I;code = 73 char = );code = 41 char = ;code = 32 char = B;code = 66 char = B;code = 66 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = b;code = 98 char = r;code = 114 char = e;code = 101 char = a;code = 97 char = s;code = 115 char = t;code = 116 char = ;code = 32 char = c;code = 99 char = a;code = 97 char = n;code = 110 char = c;code = 99 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = r;code = 114 char = i;code = 105 char = s;code = 115 char = k;code = 107 char = ;code = 32 char = o;code = 111 char = v;code = 118 char = e;code = 101 char = r;code = 114 char = a;code = 97 char = l;code = 108 char = l;code = 108 char = ;code = 32 char = (;code = 40 char = O;code = 79 char = R;code = 82 char = ,;code = 44 char = ;code = 32 char = 0;code = 48 char = .;code = 46 char = 9;code = 57 char = 8;code = 56 char = ;;code = 59 char = ;code = 32 char = 9;code = 57 char = 5;code = 53 char = %;code = 37 char = ;code = 32 char = C;code = 67 char = I;code = 73 char = ,;code = 44 char = ;code = 32 char = 0;code = 48 char = .;code = 46 char = 8;code = 56 char = 9;code = 57 char = -;code = 45 char = 1;code = 49 char = .;code = 46 char = 0;code = 48 char = 9;code = 57 char = );code = 41 char = ,;code = 44 char = ;code = 32 char = b;code = 98 char = u;code = 117 char = t;code = 116 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = B;code = 66 char = B;code = 66 char = ;code = 32 char = g;code = 103 char = e;code = 101 char = n;code = 110 char = o;code = 111 char = t;code = 116 char = y;code = 121 char = p;code = 112 char = e;code = 101 char = ;code = 32 char = w;code = 119 char = a;code = 97 char = s;code = 115 char = ;code = 32 char = a;code = 97 char = s;code = 115 char = s;code = 115 char = o;code = 111 char = c;code = 99 char = i;code = 105 char = a;code = 97 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = w;code = 119 char = i;code = 105 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = a;code = 97 char = ;code = 32 char = s;code = 115 char = i;code = 105 char = g;code = 103 char = n;code = 110 char = i;code = 105 char = f;code = 102 char = i;code = 105 char = c;code = 99 char = a;code = 97 char = n;code = 110 char = t;code = 116 char = l;code = 108 char = y;code = 121 char = ;code = 32 char = l;code = 108 char = o;code = 111 char = w;code = 119 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = r;code = 114 char = i;code = 105 char = s;code = 115 char = k;code = 107 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = a;code = 97 char = d;code = 100 char = v;code = 118 char = a;code = 97 char = n;code = 110 char = c;code = 99 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = b;code = 98 char = r;code = 114 char = e;code = 101 char = a;code = 97 char = s;code = 115 char = t;code = 116 char = ;code = 32 char = c;code = 99 char = a;code = 97 char = n;code = 110 char = c;code = 99 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = (;code = 40 char = O;code = 79 char = R;code = 82 char = ,;code = 44 char = ;code = 32 char = 0;code = 48 char = .;code = 46 char = 7;code = 55 char = 4;code = 52 char = ;;code = 59 char = ;code = 32 char = 9;code = 57 char = 5;code = 53 char = %;code = 37 char = ;code = 32 char = C;code = 67 char = I;code = 73 char = ,;code = 44 char = ;code = 32 char = 0;code = 48 char = .;code = 46 char = 6;code = 54 char = 0;code = 48 char = -;code = 45 char = 0;code = 48 char = .;code = 46 char = 9;code = 57 char = 2;code = 50 char = );code = 41 char = .;code = 46 char = <;code = 60 char = b;code = 98 char = r;code = 114 char = /;code = 47 char = >;code = 62 char = <;code = 60 char = b;code = 98 char = r;code = 114 char = /;code = 47 char = >;code = 62 char = <;code = 60 char = b;code = 98 char = >;code = 62 char = C;code = 67 char = O;code = 79 char = N;code = 78 char = C;code = 67 char = L;code = 76 char = U;code = 85 char = S;code = 83 char = I;code = 73 char = O;code = 79 char = N;code = 78 char = S;code = 83 char = ;code = 32 char = :;code = 58 char = ;code = 32 char = <;code = 60 char = /;code = 47 char = b;code = 98 char = >;code = 62 char = A;code = 65 char = l;code = 108 char = t;code = 116 char = h;code = 104 char = o;code = 111 char = u;code = 117 char = g;code = 103 char = h;code = 104 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = e;code = 101 char = v;code = 118 char = i;code = 105 char = d;code = 100 char = e;code = 101 char = n;code = 110 char = c;code = 99 char = e;code = 101 char = ;code = 32 char = f;code = 102 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = d;code = 100 char = e;code = 101 char = p;code = 112 char = e;code = 101 char = n;code = 110 char = d;code = 100 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = t;code = 116 char = r;code = 114 char = i;code = 105 char = b;code = 98 char = u;code = 117 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = s;code = 115 char = e;code = 101 char = ;code = 32 char = v;code = 118 char = a;code = 97 char = r;code = 114 char = i;code = 105 char = a;code = 97 char = n;code = 110 char = t;code = 116 char = s;code = 115 char = ;code = 32 char = t;code = 116 char = o;code = 111 char = ;code = 32 char = b;code = 98 char = r;code = 114 char = e;code = 101 char = a;code = 97 char = s;code = 115 char = t;code = 116 char = ;code = 32 char = c;code = 99 char = a;code = 97 char = n;code = 110 char = c;code = 99 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = s;code = 115 char = c;code = 99 char = e;code = 101 char = p;code = 112 char = t;code = 116 char = i;code = 105 char = b;code = 98 char = i;code = 105 char = l;code = 108 char = i;code = 105 char = t;code = 116 char = y;code = 121 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = m;code = 109 char = a;code = 97 char = i;code = 105 char = n;code = 110 char = s;code = 115 char = ;code = 32 char = e;code = 101 char = q;code = 113 char = u;code = 117 char = i;code = 105 char = v;code = 118 char = o;code = 111 char = c;code = 99 char = a;code = 97 char = l;code = 108 char = ,;code = 44 char = ;code = 32 char = f;code = 102 char = u;code = 117 char = t;code = 116 char = u;code = 117 char = r;code = 114 char = e;code = 101 char = ;code = 32 char = l;code = 108 char = a;code = 97 char = r;code = 114 char = g;code = 103 char = e;code = 101 char = ;code = 32 char = s;code = 115 char = t;code = 116 char = u;code = 117 char = d;code = 100 char = i;code = 105 char = e;code = 101 char = s;code = 115 char = ;code = 32 char = s;code = 115 char = h;code = 104 char = o;code = 111 char = u;code = 117 char = l;code = 108 char = d;code = 100 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = t;code = 116 char = e;code = 101 char = g;code = 103 char = r;code = 114 char = a;code = 97 char = t;code = 116 char = e;code = 101 char = ;code = 32 char = g;code = 103 char = e;code = 101 char = n;code = 110 char = e;code = 101 char = t;code = 116 char = i;code = 105 char = c;code = 99 char = ;code = 32 char = v;code = 118 char = a;code = 97 char = r;code = 114 char = i;code = 105 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = V;code = 86 char = D;code = 68 char = R;code = 82 char = ;code = 32 char = w;code = 119 char = i;code = 105 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = b;code = 98 char = i;code = 105 char = o;code = 111 char = m;code = 109 char = a;code = 97 char = r;code = 114 char = k;code = 107 char = e;code = 101 char = r;code = 114 char = s;code = 115 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = v;code = 118 char = i;code = 105 char = t;code = 116 char = a;code = 97 char = m;code = 109 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = D;code = 68 char = ;code = 32 char = s;code = 115 char = t;code = 116 char = a;code = 97 char = t;code = 116 char = u;code = 117 char = s;code = 115 char = .;code = 46 result sql = BACKGROUND : Vitamin D is hypothesized to lower the risk of breast cancer by inhibiting cell proliferation via the nuclear vitamin D receptor (VDR). Two common single nucleotide polymorphisms (SNP) in the VDR gene (VDR), rs1544410 (BsmI), and rs2228570 (FokI), have been inconsistently associated with breast cancer risk. Increased risk has been reported for the FokI ff genotype, which encodes a less transcriptionally active isoform of VDR, and reduced risk has been reported for the BsmI BB genotype, a SNP in strong linkage disequilibrium with a 3'-untranslated region, which may influence VDR mRNA stability.METHODS : We pooled data from 6 prospective studies in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium to examine associations between these SNPs and breast cancer among >6,300 cases and 8,100 controls for each SNP using conditional logistic regression.RESULTS : The odds ratio (OR) for the rs2228570 (FokI) ff versus FF genotype in the overall population was statistically significantly elevated [OR, 1.16; 95% confidence interval (95% CI), 1.04-1.28] but was weaker once data from the cohort with previously published positive findings were removed (OR, 1.10; 95% CI, 0.98-1.24). No association was noted between rs1544410 (BsmI) BB and breast cancer risk overall (OR, 0.98; 95% CI, 0.89-1.09), but the BB genotype was associated with a significantly lower risk of advanced breast cancer (OR, 0.74; 95% CI, 0.60-0.92).CONCLUSIONS : Although the evidence for independent contributions of these variants to breast cancer susceptibility remains equivocal, future large studies should integrate genetic variation in VDR with biomarkers of vitamin D status.
Publication: Cancer Epidemiol. Biomarkers Prev. 2009 Jan ;18(1)::297-305. :doi: 10.1158/1055-9965.EPI-08-0539.
Publication Date: 2009 Jan
Study Author(s): McKay, James D;McCullough, Marjorie L;Ziegler, Regina G;Kraft, Peter;Saltzman, Barbara S;Riboli, Elio;Barricarte, Aurelio;Berg, Christine D;Bergland, Goran;Bingham, Sheila;Brustad, Magritt;Bueno-de-Mesquita, H Bas;Burdette, Laurie;Buring, Julie;Calle, Eugenia E;Chanock, Stephen J;Clavel-Chapelon, Françoise;Cox, David G;Dossus, Laure;Feigelson, Heather Spencer;Haiman, Christopher A;Hankinson, Susan E;Hoover, Robert N;Hunter, David J;Husing, Anika;Kaaks, Rudolph;Kolonel, Laurence N;Le Marchand, Loic;Linseisen, Jakob;McCarty, Catherine A;Overvad, Kim;Panico, Salvatore;Purdue, Mark P;Stram, Daniel O;Stevens, Victoria L;Trichopoulos, Dimitrios;Willett, Walter C;Yuenger, Jeffrey;Thun, Michael J;
Institution: IARC, Lyon, France.
Shortcut link to this study:
BACKGROUND : Vitamin D is hypothesized to lower the risk of breast cancer by inhibiting cell proliferation via the nuclear vitamin D receptor (VDR). Two common single nucleotide polymorphisms (SNP) in the VDR gene (VDR), rs1544410 (BsmI), and rs2228570 (FokI), have been inconsistently associated with breast cancer risk. Increased risk has been reported for the FokI ff genotype, which encodes a less transcriptionally active isoform of VDR, and reduced risk has been reported for the BsmI BB genotype, a SNP in strong linkage disequilibrium with a 3'-untranslated region, which may influence VDR mRNA stability.METHODS : We pooled data from 6 prospective studies in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium to examine associations between these SNPs and breast cancer among >6,300 cases and 8,100 controls for each SNP using conditional logistic regression.RESULTS : The odds ratio (OR) for the rs2228570 (FokI) ff versus FF genotype in the overall population was statistically significantly elevated [OR, 1.16; 95% confidence interval (95% CI), 1.04-1.28] but was weaker once data from the cohort with previously published positive findings were removed (OR, 1.10; 95% CI, 0.98-1.24). No association was noted between rs1544410 (BsmI) BB and breast cancer risk overall (OR, 0.98; 95% CI, 0.89-1.09), but the BB genotype was associated with a significantly lower risk of advanced breast cancer (OR, 0.74; 95% CI, 0.60-0.92).CONCLUSIONS : Although the evidence for independent contributions of these variants to breast cancer susceptibility remains equivocal, future large studies should integrate genetic variation in VDR with biomarkers of vitamin D status.
PMID: 19124512