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char = t;code = 116
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char = c;code = 99
char = ;code = 32
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result sql = Chrysoeriol isolated from the leaves of Eurya ciliata stimulates proliferation and differentiation of osteoblastic MC3T3-E1 cells.
Chrysoeriol isolated from the leaves of Eurya ciliata stimulates proliferation and differentiation of osteoblastic MC3T3-E1 cells.
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char = h;code = 104
char = e;code = 101
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char = e;code = 101
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char = e;code = 101
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char = t;code = 116
char = i;code = 105
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char = n;code = 110
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char = o;code = 111
char = f;code = 102
char = ;code = 32
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char = t;code = 116
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char = o;code = 111
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result sql = Chrysoeriol (1) was isolated as the main constituent from the methanol extract of the dried leaves of Eurya ciliata Merr. To investigate the bioactivities of 1 on bone metabolism, its effects on the function of osteoblastic MC3T3-E1 cells were studied. Compound 1 significantly increased the growth of MC3T3-E1 cells and caused a significant elevation of alkaline phosphatase activity, collagen content, and nodule mineralization in the cells (P < 0.05). Our data indicate that the enhancement of osteoblast function by 1 may be useful in the prevention of osteoporosis.

Publication: J Asian Nat Prod Res 2009 Sep ;11(9)::817-23. :doi: 10.1080/10286020903117317.
Publication Date: 2009 Sep
Study Author(s): Tai, Bui Huu;Cuong, Nguyen Manh;Huong, Tran Thu;Choi, Eun-Mi;Kim, Jeong-Ah;Kim, Young Ho;
Institution: Chungnam National University, Daejeon, South Korea.
Shortcut link to this study:

Chrysoeriol (1) was isolated as the main constituent from the methanol extract of the dried leaves of Eurya ciliata Merr. To investigate the bioactivities of 1 on bone metabolism, its effects on the function of osteoblastic MC3T3-E1 cells were studied. Compound 1 significantly increased the growth of MC3T3-E1 cells and caused a significant elevation of alkaline phosphatase activity, collagen content, and nodule mineralization in the cells (P < 0.05). Our data indicate that the enhancement of osteoblast function by 1 may be useful in the prevention of osteoporosis.

PMID: 20183330

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