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result sql = Dietary vitamin D and cancers of the oral cavity and esophagus.
Dietary vitamin D and cancers of the oral cavity and esophagus.
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char = r;code = 114
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char = l;code = 108
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char = t;code = 116
char = a;code = 97
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char = n;code = 110
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char = ;code = 32
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char = r;code = 114
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char = b;code = 98
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char = C;code = 67
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char = N;code = 78
char = C;code = 67
char = L;code = 76
char = U;code = 85
char = S;code = 83
char = I;code = 73
char = O;code = 79
char = N;code = 78
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char = ;code = 32
char = <;code = 60
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char = b;code = 98
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char = e;code = 101
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char = n;code = 110
char = v;code = 118
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char = i;code = 105
char = o;code = 111
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char = s;code = 115
char = ;code = 32
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char = w;code = 119
char = e;code = 101
char = e;code = 101
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char = d;code = 100
char = i;code = 105
char = e;code = 101
char = t;code = 116
char = a;code = 97
char = r;code = 114
char = y;code = 121
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char = v;code = 118
char = i;code = 105
char = t;code = 116
char = a;code = 97
char = m;code = 109
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = D;code = 68
char = ;code = 32
char = i;code = 105
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char = e;code = 101
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char = d;code = 100
char = ;code = 32
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char = i;code = 105
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char = k;code = 107
char = ;code = 32
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char = r;code = 114
char = e;code = 101
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char = t;code = 116
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char = m;code = 109
char = o;code = 111
char = n;code = 110
char = g;code = 103
char = ;code = 32
char = h;code = 104
char = e;code = 101
char = a;code = 97
char = v;code = 118
char = y;code = 121
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char = c;code = 99
char = u;code = 117
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char = r;code = 114
char = e;code = 101
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char = t;code = 116
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char = m;code = 109
char = o;code = 111
char = k;code = 107
char = e;code = 101
char = r;code = 114
char = s;code = 115
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = h;code = 104
char = e;code = 101
char = a;code = 97
char = v;code = 118
char = y;code = 121
char = ;code = 32
char = c;code = 99
char = o;code = 111
char = n;code = 110
char = s;code = 115
char = u;code = 117
char = m;code = 109
char = e;code = 101
char = r;code = 114
char = s;code = 115
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = a;code = 97
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char = c;code = 99
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char = h;code = 104
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result sql = BACKGROUND : Data on the association between vitamin D and upper digestive tract neoplasms are limited.

METHODS : In two case-control studies in Italy, we examined the relation between dietary vitamin D intake and squamous cell carcinoma of the esophagus (SCCE; 304 cases) and oral/pharyngeal cancer (804 cases). Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated by multiple logistic regression.

RESULTS : Adjusted ORs for SCCE and oral/pharyngeal cancer were 0.58 (95% CI 0.39-0.86) and 0.76 (95% CI 0.60-0.94), respectively, for the highest tertile of vitamin D intake. Using a reference group of those in the highest tertile of vitamin D who were never/former smokers, ORs were 8.7 (95% CI 4.1-18.7) for SCCE and 10.4 (95% CI 6.9-15.5) for oral/pharyngeal cancer among heavy smokers in the lowest vitamin D tertile; similarly, compared with those in the highest tertile of vitamin D who drank <3 alcoholic drinks/day, corresponding ORs were 41.9 (95% CI 13.7-128.6) for SCCE and 8.5 (95% CI 5.7-12.5) for oral/pharyngeal cancer, among heavy alcohol drinkers in the lowest vitamin D tertile.

CONCLUSION : We observed inverse associations between dietary vitamin D intake and risk of SCCE and, perhaps, oral/pharyngeal cancer, which were most pronounced among heavy current smokers and heavy consumers of alcohol.

Publication: Ann. Oncol. 2009 Sep ;20(9)::1576-81. :doi: 10.1093/annonc/mdp036.
Publication Date: 2009 Sep
Study Author(s): Lipworth, L;Rossi, M;McLaughlin, J K;Negri, E;Talamini, R;Levi, F;Franceschi, S;La Vecchia, C;
Institution: International Epidemiology Institute, Rockville, MD 20850, USA. [email protected]
Shortcut link to this study:
BACKGROUND : Data on the association between vitamin D and upper digestive tract neoplasms are limited.

METHODS : In two case-control studies in Italy, we examined the relation between dietary vitamin D intake and squamous cell carcinoma of the esophagus (SCCE; 304 cases) and oral/pharyngeal cancer (804 cases). Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated by multiple logistic regression.

RESULTS : Adjusted ORs for SCCE and oral/pharyngeal cancer were 0.58 (95% CI 0.39-0.86) and 0.76 (95% CI 0.60-0.94), respectively, for the highest tertile of vitamin D intake. Using a reference group of those in the highest tertile of vitamin D who were never/former smokers, ORs were 8.7 (95% CI 4.1-18.7) for SCCE and 10.4 (95% CI 6.9-15.5) for oral/pharyngeal cancer among heavy smokers in the lowest vitamin D tertile; similarly, compared with those in the highest tertile of vitamin D who drank <3 alcoholic drinks/day, corresponding ORs were 41.9 (95% CI 13.7-128.6) for SCCE and 8.5 (95% CI 5.7-12.5) for oral/pharyngeal cancer, among heavy alcohol drinkers in the lowest vitamin D tertile.

CONCLUSION : We observed inverse associations between dietary vitamin D intake and risk of SCCE and, perhaps, oral/pharyngeal cancer, which were most pronounced among heavy current smokers and heavy consumers of alcohol.
PMID: 19487490

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