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result sql = Ultraviolet B irradiance and vitamin D status are inversely associated with incidence rates of pancreatic cancer worldwide.
Ultraviolet B irradiance and vitamin D status are inversely associated with incidence rates of pancreatic cancer worldwide.
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char = n;code = 110
char = ;code = 32
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char = ;code = 32
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char = l;code = 108
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char = m;code = 109
char = o;code = 111
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char = l;code = 108
char = ;code = 32
char = f;code = 102
char = o;code = 111
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char = m;code = 109
char = e;code = 101
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char = ;code = 32
char = 0;code = 48
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char = ;code = 32
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char = o;code = 111
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char = a;code = 97
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char = ;code = 32
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char = i;code = 105
char = v;code = 118
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char = ;code = 32
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char = s;code = 115
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char = e;code = 101
char = d;code = 100
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char = o;code = 111
char = m;code = 109
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char = o;code = 111
char = r;code = 114
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char = ;code = 32
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char = ;code = 32
char = <;code = 60
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char = 0;code = 48
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char = 0;code = 48
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char = d;code = 100
char = e;code = 101
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char = e;code = 101
char = s;code = 115
char = ;code = 32
char = w;code = 119
char = e;code = 101
char = r;code = 114
char = e;code = 101
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char = l;code = 108
char = f;code = 102
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char = s;code = 115
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char = h;code = 104
char = i;code = 105
char = g;code = 103
char = h;code = 104
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = c;code = 99
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char = u;code = 117
char = n;code = 110
char = t;code = 116
char = r;code = 114
char = i;code = 105
char = e;code = 101
char = s;code = 115
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
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char = s;code = 115
char = t;code = 116
char = i;code = 105
char = m;code = 109
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char = t;code = 116
char = e;code = 101
char = d;code = 100
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char = e;code = 101
char = r;code = 114
char = u;code = 117
char = m;code = 109
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char = O;code = 79
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char = );code = 41
char = D;code = 68
char = ;code = 32
char = >;code = 62
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char = 0;code = 48
char = ;code = 32
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char = g;code = 103
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char = m;code = 109
char = L;code = 76
char = ;code = 32
char = (;code = 40
char = 7;code = 55
char = 5;code = 53
char = ;code = 32
char = n;code = 110
char = m;code = 109
char = o;code = 111
char = l;code = 108
char = /;code = 47
char = L;code = 76
char = );code = 41
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = a;code = 97
char = n;code = 110
char = ;code = 32
char = i;code = 105
char = n;code = 110
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char = h;code = 104
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char = s;code = 115
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char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = <;code = 60
char = ;code = 32
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char = r;code = 114
char = ;code = 32
char = =;code = 61
char = 3;code = 51
char = 0;code = 48
char = ;code = 32
char = n;code = 110
char = g;code = 103
char = /;code = 47
char = m;code = 109
char = L;code = 76
char = .;code = 46
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = C;code = 67
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char = N;code = 78
char = C;code = 67
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char = I;code = 73
char = O;code = 79
char = N;code = 78
char = S;code = 83
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char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
char = b;code = 98
char = >;code = 62
char = C;code = 67
char = o;code = 111
char = u;code = 117
char = n;code = 110
char = t;code = 116
char = r;code = 114
char = i;code = 105
char = e;code = 101
char = s;code = 115
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = l;code = 108
char = o;code = 111
char = w;code = 119
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = U;code = 85
char = V;code = 86
char = B;code = 66
char = ;code = 32
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char = r;code = 114
char = r;code = 114
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char = h;code = 104
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char = d;code = 100
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char = i;code = 105
char = d;code = 100
char = e;code = 101
char = n;code = 110
char = c;code = 99
char = e;code = 101
char = ;code = 32
char = r;code = 114
char = a;code = 97
char = t;code = 116
char = e;code = 101
char = s;code = 115
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = p;code = 112
char = a;code = 97
char = n;code = 110
char = c;code = 99
char = r;code = 114
char = e;code = 101
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = c;code = 99
char = ;code = 32
char = c;code = 99
char = a;code = 97
char = n;code = 110
char = c;code = 99
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = b;code = 98
char = o;code = 111
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = h;code = 104
char = e;code = 101
char = m;code = 109
char = i;code = 105
char = s;code = 115
char = p;code = 112
char = h;code = 104
char = e;code = 101
char = r;code = 114
char = e;code = 101
char = s;code = 115
char = ,;code = 44
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = o;code = 111
char = c;code = 99
char = c;code = 99
char = a;code = 97
char = s;code = 115
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = e;code = 101
char = x;code = 120
char = c;code = 99
char = e;code = 101
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char = o;code = 111
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result sql = OBJECTIVES : To determine if an inverse association exits between latitude, ultraviolet B (UVB) irradiance and incidence rates of pancreatic cancer worldwide.

METHODS : Multiple linear regression was used to investigate the relationship and between UVB irradiance incidence rates of pancreatic cancer and while controlling for cigarette, alcohol and sugar consumption, and proportion overweight. Serum 25-hydroxyvitamin D [25(OH)D] levels were estimated, and their association with incidence rates also was analyzed.

RESULTS : Incidence rates were higher at higher latitudes (R2 for latitude for men, 0.51; P < 0.001; R2 for latitude for women, 0.32; P < 0.001). Ultraviolet B irradiance also was independently inversely associated with incidence in men (P < 0.01) and women (P = 0.02). Alcohol (P < 0.0001) and cigarette (P < or = 0.01) consumption were positively associated with incidence in men (R2 for overall model for men, 0.76; P < 0.0001). Alcohol (P < 0.0001) and sugar (P = 0.001) consumption were positively associated with incidence rates in women (R2 for overall model for women, 0.64; P < 0.0001). Incidence rates were half as high in countries with estimated serum 25(OH)D >30 ng/mL (75 nmol/L) than in those with < or =30 ng/mL.

CONCLUSIONS : Countries with lower UVB irradiance had higher incidence rates of pancreatic cancer in both hemispheres, with occasional exceptions.

Publication: Pancreas 2010 Jul ;39(5)::669-74. :doi: 10.1097/MPA.0b013e3181ce654d.
Publication Date: 2010 Jul
Study Author(s): Mohr, Sharif B;Garland, Cedric F;Gorham, Edward D;Grant, William B;Garland, Frank C;
Institution: Naval Health Research Center, San Diego, CA, USA.
Shortcut link to this study:
OBJECTIVES : To determine if an inverse association exits between latitude, ultraviolet B (UVB) irradiance and incidence rates of pancreatic cancer worldwide.

METHODS : Multiple linear regression was used to investigate the relationship and between UVB irradiance incidence rates of pancreatic cancer and while controlling for cigarette, alcohol and sugar consumption, and proportion overweight. Serum 25-hydroxyvitamin D [25(OH)D] levels were estimated, and their association with incidence rates also was analyzed.

RESULTS : Incidence rates were higher at higher latitudes (R2 for latitude for men, 0.51; P < 0.001; R2 for latitude for women, 0.32; P < 0.001). Ultraviolet B irradiance also was independently inversely associated with incidence in men (P < 0.01) and women (P = 0.02). Alcohol (P < 0.0001) and cigarette (P < or = 0.01) consumption were positively associated with incidence in men (R2 for overall model for men, 0.76; P < 0.0001). Alcohol (P < 0.0001) and sugar (P = 0.001) consumption were positively associated with incidence rates in women (R2 for overall model for women, 0.64; P < 0.0001). Incidence rates were half as high in countries with estimated serum 25(OH)D >30 ng/mL (75 nmol/L) than in those with < or =30 ng/mL.

CONCLUSIONS : Countries with lower UVB irradiance had higher incidence rates of pancreatic cancer in both hemispheres, with occasional exceptions.
PMID: 20442683

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