char = C;code = 67 char = a;code = 97 char = s;code = 115 char = e;code = 101 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = p;code = 112 char = h;code = 104 char = o;code = 111 char = s;code = 115 char = p;code = 112 char = h;code = 104 char = o;code = 111 char = p;code = 112 char = e;code = 101 char = p;code = 112 char = t;code = 116 char = i;code = 105 char = d;code = 100 char = e;code = 101 char = -;code = 45 char = a;code = 97 char = m;code = 109 char = o;code = 111 char = r;code = 114 char = p;code = 112 char = h;code = 104 char = o;code = 111 char = u;code = 117 char = s;code = 115 char = ;code = 32 char = c;code = 99 char = a;code = 97 char = l;code = 108 char = c;code = 99 char = i;code = 105 char = u;code = 117 char = m;code = 109 char = ;code = 32 char = p;code = 112 char = h;code = 104 char = o;code = 111 char = s;code = 115 char = p;code = 112 char = h;code = 104 char = a;code = 97 char = t;code = 116 char = e;code = 101 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = c;code = 99 char = o;code = 111 char = r;code = 114 char = p;code = 112 char = o;code = 111 char = r;code = 114 char = a;code = 97 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = t;code = 116 char = o;code = 111 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = g;code = 103 char = a;code = 97 char = r;code = 114 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = f;code = 102 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = h;code = 104 char = i;code = 105 char = b;code = 98 char = i;code = 105 char = t;code = 116 char = s;code = 115 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = p;code = 112 char = r;code = 114 char = o;code = 111 char = g;code = 103 char = r;code = 114 char = e;code = 101 char = s;code = 115 char = s;code = 115 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = e;code = 101 char = n;code = 110 char = a;code = 97 char = m;code = 109 char = e;code = 101 char = l;code = 108 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = b;code = 98 char = s;code = 115 char = u;code = 117 char = r;code = 114 char = f;code = 102 char = a;code = 97 char = c;code = 99 char = e;code = 101 char = ;code = 32 char = l;code = 108 char = e;code = 101 char = s;code = 115 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = s;code = 115 char = i;code = 105 char = t;code = 116 char = u;code = 117 char = .;code = 46 result sql = Casein phosphopeptide-amorphous calcium phosphate incorporated into sugar confections inhibits the progression of enamel subsurface lesions in situ.
Casein phosphopeptide-amorphous calcium phosphate incorporated into sugar confections inhibits the progression of enamel subsurface lesions in situ.char = C;code = 67 char = a;code = 97 char = s;code = 115 char = e;code = 101 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = p;code = 112 char = h;code = 104 char = o;code = 111 char = s;code = 115 char = p;code = 112 char = h;code = 104 char = o;code = 111 char = p;code = 112 char = e;code = 101 char = p;code = 112 char = t;code = 116 char = i;code = 105 char = d;code = 100 char = e;code = 101 char = -;code = 45 char = a;code = 97 char = m;code = 109 char = o;code = 111 char = r;code = 114 char = p;code = 112 char = h;code = 104 char = o;code = 111 char = u;code = 117 char = s;code = 115 char = ;code = 32 char = c;code = 99 char = a;code = 97 char = l;code = 108 char = c;code = 99 char = i;code = 105 char = u;code = 117 char = m;code = 109 char = ;code = 32 char = p;code = 112 char = h;code = 104 char = o;code = 111 char = s;code = 115 char = p;code = 112 char = h;code = 104 char = a;code = 97 char = t;code = 116 char = e;code = 101 char = ;code = 32 char = (;code = 40 char = C;code = 67 char = P;code = 80 char = P;code = 80 char = -;code = 45 char = A;code = 65 char = C;code = 67 char = P;code = 80 char = );code = 41 char = ;code = 32 char = h;code = 104 char = a;code = 97 char = s;code = 115 char = ;code = 32 char = b;code = 98 char = e;code = 101 char = e;code = 101 char = n;code = 110 char = ;code = 32 char = d;code = 100 char = e;code = 101 char = m;code = 109 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = t;code = 116 char = r;code = 114 char = a;code = 97 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = t;code = 116 char = o;code = 111 char = ;code = 32 char = e;code = 101 char = x;code = 120 char = h;code = 104 char = i;code = 105 char = b;code = 98 char = i;code = 105 char = t;code = 116 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = t;code = 116 char = i;code = 105 char = c;code = 99 char = a;code = 97 char = r;code = 114 char = i;code = 105 char = o;code = 111 char = g;code = 103 char = e;code = 101 char = n;code = 110 char = i;code = 105 char = c;code = 99 char = ;code = 32 char = a;code = 97 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = i;code = 105 char = t;code = 116 char = y;code = 121 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = r;code = 114 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = o;code = 111 char = m;code = 109 char = i;code = 105 char = z;code = 122 char = e;code = 101 char = d;code = 100 char = ,;code = 44 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = t;code = 116 char = r;code = 114 char = o;code = 111 char = l;code = 108 char = l;code = 108 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = c;code = 99 char = l;code = 108 char = i;code = 105 char = n;code = 110 char = i;code = 105 char = c;code = 99 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = t;code = 116 char = r;code = 114 char = i;code = 105 char = a;code = 97 char = l;code = 108 char = s;code = 115 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = g;code = 103 char = a;code = 97 char = r;code = 114 char = -;code = 45 char = f;code = 102 char = r;code = 114 char = e;code = 101 char = e;code = 101 char = ;code = 32 char = g;code = 103 char = u;code = 117 char = m;code = 109 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = a;code = 97 char = ;code = 32 char = t;code = 116 char = o;code = 111 char = o;code = 111 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = c;code = 99 char = r;code = 114 char = e;code = 101 char = a;code = 97 char = m;code = 109 char = .;code = 46 char = ;code = 32 char = T;code = 84 char = w;code = 119 char = o;code = 111 char = ;code = 32 char = r;code = 114 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = o;code = 111 char = m;code = 109 char = i;code = 105 char = z;code = 122 char = e;code = 101 char = d;code = 100 char = ,;code = 44 char = ;code = 32 char = d;code = 100 char = o;code = 111 char = u;code = 117 char = b;code = 98 char = l;code = 108 char = e;code = 101 char = -;code = 45 char = b;code = 98 char = l;code = 108 char = i;code = 105 char = n;code = 110 char = d;code = 100 char = ,;code = 44 char = ;code = 32 char = c;code = 99 char = r;code = 114 char = o;code = 111 char = s;code = 115 char = s;code = 115 char = o;code = 111 char = v;code = 118 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = s;code = 115 char = t;code = 116 char = u;code = 117 char = d;code = 100 char = i;code = 105 char = e;code = 101 char = s;code = 115 char = ;code = 32 char = w;code = 119 char = e;code = 101 char = r;code = 114 char = e;code = 101 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = d;code = 100 char = u;code = 117 char = c;code = 99 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = t;code = 116 char = o;code = 111 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = v;code = 118 char = e;code = 101 char = s;code = 115 char = t;code = 116 char = i;code = 105 char = g;code = 103 char = a;code = 97 char = t;code = 116 char = e;code = 101 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = p;code = 112 char = o;code = 111 char = t;code = 116 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = i;code = 105 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = C;code = 67 char = P;code = 80 char = P;code = 80 char = -;code = 45 char = A;code = 65 char = C;code = 67 char = P;code = 80 char = ;code = 32 char = a;code = 97 char = d;code = 100 char = d;code = 100 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = t;code = 116 char = o;code = 111 char = ;code = 32 char = h;code = 104 char = a;code = 97 char = r;code = 114 char = d;code = 100 char = ;code = 32 char = c;code = 99 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = y;code = 121 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = f;code = 102 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = ;code = 32 char = t;code = 116 char = o;code = 111 char = ;code = 32 char = s;code = 115 char = l;code = 108 char = o;code = 111 char = w;code = 119 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = p;code = 112 char = r;code = 114 char = o;code = 111 char = g;code = 103 char = r;code = 114 char = e;code = 101 char = s;code = 115 char = s;code = 115 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = e;code = 101 char = n;code = 110 char = a;code = 97 char = m;code = 109 char = e;code = 101 char = l;code = 108 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = b;code = 98 char = s;code = 115 char = u;code = 117 char = r;code = 114 char = f;code = 102 char = a;code = 97 char = c;code = 99 char = e;code = 101 char = ;code = 32 char = l;code = 108 char = e;code = 101 char = s;code = 115 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = s;code = 115 char = i;code = 105 char = t;code = 116 char = u;code = 117 char = ;code = 32 char = m;code = 109 char = o;code = 111 char = d;code = 100 char = e;code = 101 char = l;code = 108 char = .;code = 46 char = ;code = 32 char = <;code = 60 char = b;code = 98 char = >;code = 62 char = T;code = 84 char = H;code = 72 char = E;code = 69 char = ;code = 32 char = C;code = 67 char = O;code = 79 char = N;code = 78 char = F;code = 70 char = E;code = 69 char = C;code = 67 char = T;code = 84 char = I;code = 73 char = O;code = 79 char = N;code = 78 char = S;code = 83 char = ;code = 32 char = S;code = 83 char = T;code = 84 char = U;code = 85 char = D;code = 68 char = I;code = 73 char = E;code = 69 char = D;code = 68 char = ;code = 32 char = W;code = 87 char = E;code = 69 char = R;code = 82 char = E;code = 69 char = :;code = 58 char = ;code = 32 char = <;code = 60 char = /;code = 47 char = b;code = 98 char = >;code = 62 char = ;code = 32 char = (;code = 40 char = 1;code = 49 char = );code = 41 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = t;code = 116 char = r;code = 114 char = o;code = 111 char = l;code = 108 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = g;code = 103 char = a;code = 97 char = r;code = 114 char = ;code = 32 char = (;code = 40 char = 6;code = 54 char = 5;code = 53 char = %;code = 37 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = c;code = 99 char = r;code = 114 char = o;code = 111 char = s;code = 115 char = e;code = 101 char = ;code = 32 char = +;code = 43 char = ;code = 32 char = 3;code = 51 char = 3;code = 51 char = %;code = 37 char = ;code = 32 char = g;code = 103 char = l;code = 108 char = u;code = 117 char = c;code = 99 char = o;code = 111 char = s;code = 115 char = e;code = 101 char = ;code = 32 char = s;code = 115 char = y;code = 121 char = r;code = 114 char = u;code = 117 char = p;code = 112 char = );code = 41 char = ;;code = 59 char = ;code = 32 char = (;code = 40 char = 2;code = 50 char = );code = 41 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = t;code = 116 char = r;code = 114 char = o;code = 111 char = l;code = 108 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = g;code = 103 char = a;code = 97 char = r;code = 114 char = -;code = 45 char = f;code = 102 char = r;code = 114 char = e;code = 101 char = e;code = 101 char = ;;code = 59 char = ;code = 32 char = (;code = 40 char = 3;code = 51 char = );code = 41 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = g;code = 103 char = a;code = 97 char = r;code = 114 char = ;code = 32 char = +;code = 43 char = ;code = 32 char = 0;code = 48 char = .;code = 46 char = 5;code = 53 char = %;code = 37 char = ;code = 32 char = (;code = 40 char = w;code = 119 char = /;code = 47 char = w;code = 119 char = );code = 41 char = ;code = 32 char = C;code = 67 char = P;code = 80 char = P;code = 80 char = -;code = 45 char = A;code = 65 char = C;code = 67 char = P;code = 80 char = ;;code = 59 char = ;code = 32 char = (;code = 40 char = 4;code = 52 char = );code = 41 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = g;code = 103 char = a;code = 97 char = r;code = 114 char = ;code = 32 char = +;code = 43 char = ;code = 32 char = 1;code = 49 char = .;code = 46 char = 0;code = 48 char = %;code = 37 char = ;code = 32 char = (;code = 40 char = w;code = 119 char = /;code = 47 char = w;code = 119 char = );code = 41 char = ;code = 32 char = C;code = 67 char = P;code = 80 char = P;code = 80 char = -;code = 45 char = A;code = 65 char = C;code = 67 char = P;code = 80 char = ;;code = 59 char = ;code = 32 char = (;code = 40 char = 5;code = 53 char = );code = 41 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = g;code = 103 char = a;code = 97 char = r;code = 114 char = -;code = 45 char = f;code = 102 char = r;code = 114 char = e;code = 101 char = e;code = 101 char = ;code = 32 char = +;code = 43 char = ;code = 32 char = 0;code = 48 char = .;code = 46 char = 5;code = 53 char = %;code = 37 char = ;code = 32 char = (;code = 40 char = w;code = 119 char = /;code = 47 char = w;code = 119 char = );code = 41 char = ;code = 32 char = C;code = 67 char = P;code = 80 char = P;code = 80 char = -;code = 45 char = A;code = 65 char = C;code = 67 char = P;code = 80 char = .;code = 46 char = ;code = 32 char = P;code = 80 char = a;code = 97 char = r;code = 114 char = t;code = 116 char = i;code = 105 char = c;code = 99 char = i;code = 105 char = p;code = 112 char = a;code = 97 char = n;code = 110 char = t;code = 116 char = s;code = 115 char = ;code = 32 char = (;code = 40 char = 1;code = 49 char = 0;code = 48 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = 1;code = 49 char = 4;code = 52 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = s;code = 115 char = t;code = 116 char = u;code = 117 char = d;code = 100 char = y;code = 121 char = ;code = 32 char = 1;code = 49 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = 2;code = 50 char = );code = 41 char = ;code = 32 char = w;code = 119 char = o;code = 111 char = r;code = 114 char = e;code = 101 char = ;code = 32 char = a;code = 97 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = m;code = 109 char = o;code = 111 char = v;code = 118 char = a;code = 97 char = b;code = 98 char = l;code = 108 char = e;code = 101 char = ;code = 32 char = p;code = 112 char = a;code = 97 char = l;code = 108 char = a;code = 97 char = t;code = 116 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = a;code = 97 char = p;code = 112 char = p;code = 112 char = l;code = 108 char = i;code = 105 char = a;code = 97 char = n;code = 110 char = c;code = 99 char = e;code = 101 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = t;code = 116 char = a;code = 97 char = i;code = 105 char = n;code = 110 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = ;code = 32 char = e;code = 101 char = n;code = 110 char = a;code = 97 char = m;code = 109 char = e;code = 101 char = l;code = 108 char = ;code = 32 char = h;code = 104 char = a;code = 97 char = l;code = 108 char = f;code = 102 char = -;code = 45 char = s;code = 115 char = l;code = 108 char = a;code = 97 char = b;code = 98 char = s;code = 115 char = ;code = 32 char = w;code = 119 char = i;code = 105 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = b;code = 98 char = s;code = 115 char = u;code = 117 char = r;code = 114 char = f;code = 102 char = a;code = 97 char = c;code = 99 char = e;code = 101 char = ;code = 32 char = l;code = 108 char = e;code = 101 char = s;code = 115 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = ,;code = 44 char = ;code = 32 char = e;code = 101 char = x;code = 120 char = c;code = 99 char = e;code = 101 char = p;code = 112 char = t;code = 116 char = ;code = 32 char = f;code = 102 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = m;code = 109 char = e;code = 101 char = a;code = 97 char = l;code = 108 char = s;code = 115 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = o;code = 111 char = r;code = 114 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = h;code = 104 char = y;code = 121 char = g;code = 103 char = i;code = 105 char = e;code = 101 char = n;code = 110 char = e;code = 101 char = ;code = 32 char = p;code = 112 char = r;code = 114 char = o;code = 111 char = c;code = 99 char = e;code = 101 char = d;code = 100 char = u;code = 117 char = r;code = 114 char = e;code = 101 char = s;code = 115 char = ,;code = 44 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = u;code = 117 char = m;code = 109 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = 1;code = 49 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = f;code = 102 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = 6;code = 54 char = ;code = 32 char = t;code = 116 char = i;code = 105 char = m;code = 109 char = e;code = 101 char = s;code = 115 char = ;code = 32 char = a;code = 97 char = ;code = 32 char = d;code = 100 char = a;code = 97 char = y;code = 121 char = ;code = 32 char = f;code = 102 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = 1;code = 49 char = 0;code = 48 char = ;code = 32 char = d;code = 100 char = a;code = 97 char = y;code = 121 char = s;code = 115 char = .;code = 46 char = ;code = 32 char = T;code = 84 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = e;code = 101 char = n;code = 110 char = a;code = 97 char = m;code = 109 char = e;code = 101 char = l;code = 108 char = ;code = 32 char = h;code = 104 char = a;code = 97 char = l;code = 108 char = f;code = 102 char = -;code = 45 char = s;code = 115 char = l;code = 108 char = a;code = 97 char = b;code = 98 char = s;code = 115 char = ;code = 32 char = w;code = 119 char = e;code = 101 char = r;code = 114 char = e;code = 101 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = s;code = 115 char = e;code = 101 char = t;code = 116 char = ;code = 32 char = t;code = 116 char = o;code = 111 char = ;code = 32 char = a;code = 97 char = l;code = 108 char = l;code = 108 char = o;code = 111 char = w;code = 119 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = d;code = 100 char = e;code = 101 char = v;code = 118 char = e;code = 101 char = l;code = 108 char = o;code = 111 char = p;code = 112 char = m;code = 109 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = p;code = 112 char = l;code = 108 char = a;code = 97 char = q;code = 113 char = u;code = 117 char = e;code = 101 char = ;code = 32 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = e;code = 101 char = n;code = 110 char = a;code = 97 char = m;code = 109 char = e;code = 101 char = l;code = 108 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = r;code = 114 char = f;code = 102 char = a;code = 97 char = c;code = 99 char = e;code = 101 char = .;code = 46 char = ;code = 32 char = P;code = 80 char = a;code = 97 char = r;code = 114 char = t;code = 116 char = i;code = 105 char = c;code = 99 char = i;code = 105 char = p;code = 112 char = a;code = 97 char = n;code = 110 char = t;code = 116 char = s;code = 115 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = s;code = 115 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = f;code = 102 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = 1;code = 49 char = ;code = 32 char = w;code = 119 char = e;code = 101 char = e;code = 101 char = k;code = 107 char = ;code = 32 char = b;code = 98 char = e;code = 101 char = f;code = 102 char = o;code = 111 char = r;code = 114 char = e;code = 101 char = ;code = 32 char = c;code = 99 char = r;code = 114 char = o;code = 111 char = s;code = 115 char = s;code = 115 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = ;code = 32 char = o;code = 111 char = v;code = 118 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = t;code = 116 char = o;code = 111 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = o;code = 111 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = f;code = 102 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = .;code = 46 char = ;code = 32 char = T;code = 84 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = a;code = 97 char = p;code = 112 char = p;code = 112 char = l;code = 108 char = i;code = 105 char = a;code = 97 char = n;code = 110 char = c;code = 99 char = e;code = 101 char = s;code = 115 char = ;code = 32 char = w;code = 119 char = e;code = 101 char = r;code = 114 char = e;code = 101 char = ;code = 32 char = s;code = 115 char = t;code = 116 char = o;code = 111 char = r;code = 114 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = a;code = 97 char = ;code = 32 char = h;code = 104 char = u;code = 117 char = m;code = 109 char = i;code = 105 char = d;code = 100 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = t;code = 116 char = a;code = 97 char = i;code = 105 char = n;code = 110 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = a;code = 97 char = t;code = 116 char = ;code = 32 char = 3;code = 51 char = 7;code = 55 char = ;code = 32 char = d;code = 100 char = e;code = 101 char = g;code = 103 char = r;code = 114 char = e;code = 101 char = e;code = 101 char = s;code = 115 char = ;code = 32 char = C;code = 67 char = ;code = 32 char = w;code = 119 char = h;code = 104 char = e;code = 101 char = n;code = 110 char = ;code = 32 char = n;code = 110 char = o;code = 111 char = t;code = 116 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = m;code = 109 char = o;code = 111 char = u;code = 117 char = t;code = 116 char = h;code = 104 char = .;code = 46 char = ;code = 32 char = A;code = 65 char = f;code = 102 char = t;code = 116 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = e;code = 101 char = a;code = 97 char = c;code = 99 char = h;code = 104 char = ;code = 32 char = t;code = 116 char = r;code = 114 char = e;code = 101 char = a;code = 97 char = t;code = 116 char = m;code = 109 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = ;code = 32 char = p;code = 112 char = e;code = 101 char = r;code = 114 char = i;code = 105 char = o;code = 111 char = d;code = 100 char = ,;code = 44 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = e;code = 101 char = n;code = 110 char = a;code = 97 char = m;code = 109 char = e;code = 101 char = l;code = 108 char = ;code = 32 char = h;code = 104 char = a;code = 97 char = l;code = 108 char = f;code = 102 char = -;code = 45 char = s;code = 115 char = l;code = 108 char = a;code = 97 char = b;code = 98 char = s;code = 115 char = ;code = 32 char = w;code = 119 char = e;code = 101 char = r;code = 114 char = e;code = 101 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = m;code = 109 char = o;code = 111 char = v;code = 118 char = e;code = 101 char = d;code = 100 char = ,;code = 44 char = ;code = 32 char = p;code = 112 char = a;code = 97 char = i;code = 105 char = r;code = 114 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = w;code = 119 char = i;code = 105 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = i;code = 105 char = r;code = 114 char = ;code = 32 char = d;code = 100 char = e;code = 101 char = m;code = 109 char = i;code = 105 char = n;code = 110 char = e;code = 101 char = r;code = 114 char = a;code = 97 char = l;code = 108 char = i;code = 105 char = z;code = 122 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = t;code = 116 char = r;code = 114 char = o;code = 111 char = l;code = 108 char = ;code = 32 char = h;code = 104 char = a;code = 97 char = l;code = 108 char = f;code = 102 char = -;code = 45 char = s;code = 115 char = l;code = 108 char = a;code = 97 char = b;code = 98 char = s;code = 115 char = ,;code = 44 char = ;code = 32 char = e;code = 101 char = m;code = 109 char = b;code = 98 char = e;code = 101 char = d;code = 100 char = d;code = 100 char = e;code = 101 char = d;code = 100 char = ,;code = 44 char = ;code = 32 char = s;code = 115 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = n;code = 110 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = a;code = 97 char = l;code = 108 char = y;code = 121 char = s;code = 115 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = u;code = 117 char = s;code = 115 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = ;code = 32 char = t;code = 116 char = r;code = 114 char = a;code = 97 char = n;code = 110 char = s;code = 115 char = v;code = 118 char = e;code = 101 char = r;code = 114 char = s;code = 115 char = e;code = 101 char = ;code = 32 char = m;code = 109 char = i;code = 105 char = c;code = 99 char = r;code = 114 char = o;code = 111 char = r;code = 114 char = a;code = 97 char = d;code = 100 char = i;code = 105 char = o;code = 111 char = g;code = 103 char = r;code = 114 char = a;code = 97 char = p;code = 112 char = h;code = 104 char = y;code = 121 char = .;code = 46 char = ;code = 32 char = I;code = 73 char = n;code = 110 char = ;code = 32 char = b;code = 98 char = o;code = 111 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = s;code = 115 char = t;code = 116 char = u;code = 117 char = d;code = 100 char = i;code = 105 char = e;code = 101 char = s;code = 115 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = u;code = 117 char = m;code = 109 char = p;code = 112 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = t;code = 116 char = r;code = 114 char = o;code = 111 char = l;code = 108 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = g;code = 103 char = a;code = 97 char = r;code = 114 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = f;code = 102 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = s;code = 115 char = u;code = 117 char = l;code = 108 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = s;code = 115 char = i;code = 105 char = g;code = 103 char = n;code = 110 char = i;code = 105 char = f;code = 102 char = i;code = 105 char = c;code = 99 char = a;code = 97 char = n;code = 110 char = t;code = 116 char = ;code = 32 char = d;code = 100 char = e;code = 101 char = m;code = 109 char = i;code = 105 char = n;code = 110 char = e;code = 101 char = r;code = 114 char = a;code = 97 char = l;code = 108 char = i;code = 105 char = z;code = 122 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = (;code = 40 char = p;code = 112 char = r;code = 114 char = o;code = 111 char = g;code = 103 char = r;code = 114 char = e;code = 101 char = s;code = 115 char = s;code = 115 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = );code = 41 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = e;code = 101 char = n;code = 110 char = a;code = 97 char = m;code = 109 char = e;code = 101 char = l;code = 108 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = b;code = 98 char = s;code = 115 char = u;code = 117 char = r;code = 114 char = f;code = 102 char = a;code = 97 char = c;code = 99 char = e;code = 101 char = ;code = 32 char = l;code = 108 char = e;code = 101 char = s;code = 115 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = .;code = 46 char = ;code = 32 char = H;code = 72 char = o;code = 111 char = w;code = 119 char = e;code = 101 char = v;code = 118 char = e;code = 101 char = r;code = 114 char = ,;code = 44 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = u;code = 117 char = m;code = 109 char = p;code = 112 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = g;code = 103 char = a;code = 97 char = r;code = 114 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = f;code = 102 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = t;code = 116 char = a;code = 97 char = i;code = 105 char = n;code = 110 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = ;code = 32 char = C;code = 67 char = P;code = 80 char = P;code = 80 char = -;code = 45 char = A;code = 65 char = C;code = 67 char = P;code = 80 char = ;code = 32 char = d;code = 100 char = i;code = 105 char = d;code = 100 char = ;code = 32 char = n;code = 110 char = o;code = 111 char = t;code = 116 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = s;code = 115 char = u;code = 117 char = l;code = 108 char = t;code = 116 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = l;code = 108 char = e;code = 101 char = s;code = 115 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = p;code = 112 char = r;code = 114 char = o;code = 111 char = g;code = 103 char = r;code = 114 char = e;code = 101 char = s;code = 115 char = s;code = 115 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ,;code = 44 char = ;code = 32 char = b;code = 98 char = u;code = 117 char = t;code = 116 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = f;code = 102 char = a;code = 97 char = c;code = 99 char = t;code = 116 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = s;code = 115 char = i;code = 105 char = g;code = 103 char = n;code = 110 char = i;code = 105 char = f;code = 102 char = i;code = 105 char = c;code = 99 char = a;code = 97 char = n;code = 110 char = t;code = 116 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = m;code = 109 char = i;code = 105 char = n;code = 110 char = e;code = 101 char = r;code = 114 char = a;code = 97 char = l;code = 108 char = i;code = 105 char = z;code = 122 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = (;code = 40 char = r;code = 114 char = e;code = 101 char = g;code = 103 char = r;code = 114 char = e;code = 101 char = s;code = 115 char = s;code = 115 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = );code = 41 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = l;code = 108 char = e;code = 101 char = s;code = 115 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = .;code = 46 char = ;code = 32 char = R;code = 82 char = e;code = 101 char = m;code = 109 char = i;code = 105 char = n;code = 110 char = e;code = 101 char = r;code = 114 char = a;code = 97 char = l;code = 108 char = i;code = 105 char = z;code = 122 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = b;code = 98 char = y;code = 121 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = u;code = 117 char = m;code = 109 char = p;code = 112 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = g;code = 103 char = a;code = 97 char = r;code = 114 char = ;code = 32 char = +;code = 43 char = ;code = 32 char = 1;code = 49 char = .;code = 46 char = 0;code = 48 char = %;code = 37 char = ;code = 32 char = C;code = 67 char = P;code = 80 char = P;code = 80 char = -;code = 45 char = A;code = 65 char = C;code = 67 char = P;code = 80 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = f;code = 102 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = w;code = 119 char = a;code = 97 char = s;code = 115 char = ;code = 32 char = s;code = 115 char = i;code = 105 char = g;code = 103 char = n;code = 110 char = i;code = 105 char = f;code = 102 char = i;code = 105 char = c;code = 99 char = a;code = 97 char = n;code = 110 char = t;code = 116 char = l;code = 108 char = y;code = 121 char = ;code = 32 char = g;code = 103 char = r;code = 114 char = e;code = 101 char = a;code = 97 char = t;code = 116 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = a;code = 97 char = n;code = 110 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = a;code = 97 char = t;code = 116 char = ;code = 32 char = o;code = 111 char = b;code = 98 char = t;code = 116 char = a;code = 97 char = i;code = 105 char = n;code = 110 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = w;code = 119 char = i;code = 105 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = g;code = 103 char = a;code = 97 char = r;code = 114 char = -;code = 45 char = f;code = 102 char = r;code = 114 char = e;code = 101 char = e;code = 101 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = f;code = 102 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = .;code = 46 char = <;code = 60 char = b;code = 98 char = r;code = 114 char = /;code = 47 char = >;code = 62 result sql = Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) has been demonstrated to exhibit anticariogenic activity in randomized, controlled clinical trials of sugar-free gum and a tooth cream. Two randomized, double-blind, crossover studies were conducted to investigate the potential of CPP-ACP added to hard candy confections to slow the progression of enamel subsurface lesions in an in situ model. THE CONFECTIONS STUDIED WERE: (1) control sugar (65% sucrose + 33% glucose syrup); (2) control sugar-free; (3) sugar + 0.5% (w/w) CPP-ACP; (4) sugar + 1.0% (w/w) CPP-ACP; (5) sugar-free + 0.5% (w/w) CPP-ACP. Participants (10 and 14 in study 1 and 2) wore a removable palatal appliance containing enamel half-slabs with subsurface lesions, except for meals and oral hygiene procedures, and consumed 1 confection 6 times a day for 10 days. The enamel half-slabs were inset to allow the development of plaque on the enamel surface. Participants rested for 1 week before crossing over to another confection. The appliances were stored in a humid container at 37 degrees C when not in the mouth. After each treatment period, the enamel half-slabs were removed, paired with their demineralized control half-slabs, embedded, sectioned and then analysed using transverse microradiography. In both studies consumption of the control sugar confection resulted in significant demineralization (progression) of the enamel subsurface lesions. However, consumption of the sugar confections containing CPP-ACP did not result in lesion progression, but in fact in significant remineralization (regression) of the lesions. Remineralization by consumption of the sugar + 1.0% CPP-ACP confection was significantly greater than that obtained with the sugar-free confection.
Publication: Caries Res. 2010 ;44(1)::33-40. :doi: 10.1159/000275572.
Publication Date: 2010
Study Author(s): Walker, G D;Cai, F;Shen, P;Adams, G G;Reynolds, C;Reynolds, E C;
Institution: Cooperative Research Centre for Oral Health Science, Melbourne Dental School, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Melbourne, Vic., Australia.
Shortcut link to this study:
Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) has been demonstrated to exhibit anticariogenic activity in randomized, controlled clinical trials of sugar-free gum and a tooth cream. Two randomized, double-blind, crossover studies were conducted to investigate the potential of CPP-ACP added to hard candy confections to slow the progression of enamel subsurface lesions in an in situ model. THE CONFECTIONS STUDIED WERE: (1) control sugar (65% sucrose + 33% glucose syrup); (2) control sugar-free; (3) sugar + 0.5% (w/w) CPP-ACP; (4) sugar + 1.0% (w/w) CPP-ACP; (5) sugar-free + 0.5% (w/w) CPP-ACP. Participants (10 and 14 in study 1 and 2) wore a removable palatal appliance containing enamel half-slabs with subsurface lesions, except for meals and oral hygiene procedures, and consumed 1 confection 6 times a day for 10 days. The enamel half-slabs were inset to allow the development of plaque on the enamel surface. Participants rested for 1 week before crossing over to another confection. The appliances were stored in a humid container at 37 degrees C when not in the mouth. After each treatment period, the enamel half-slabs were removed, paired with their demineralized control half-slabs, embedded, sectioned and then analysed using transverse microradiography. In both studies consumption of the control sugar confection resulted in significant demineralization (progression) of the enamel subsurface lesions. However, consumption of the sugar confections containing CPP-ACP did not result in lesion progression, but in fact in significant remineralization (regression) of the lesions. Remineralization by consumption of the sugar + 1.0% CPP-ACP confection was significantly greater than that obtained with the sugar-free confection.
PMID: 20090326