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char = p;code = 112
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char = l;code = 108
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char = t;code = 116
char = u;code = 117
char = s;code = 115
char = .;code = 46
result sql = Association of serum lipoprotein ratios with insulin resistance in type 2 diabetes mellitus.
Association of serum lipoprotein ratios with insulin resistance in type 2 diabetes mellitus.
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char = B;code = 66
char = A;code = 65
char = C;code = 67
char = K;code = 75
char = G;code = 71
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char = O;code = 79
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char = N;code = 78
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char = <;code = 60
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char = (;code = 40
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char = C;code = 67
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char = p;code = 112
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char = o;code = 111
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char = (;code = 40
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char = L;code = 76
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char = u;code = 117
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char = ;code = 32
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char = L;code = 76
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char = );code = 41
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char = L;code = 76
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char = G;code = 71
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char = e;code = 101
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char = e;code = 101
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char = W;code = 87
char = C;code = 67
char = );code = 41
char = ;code = 32
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char = d;code = 100
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char = w;code = 119
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char = e;code = 101
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char = g;code = 103
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char = i;code = 105
char = f;code = 102
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char = a;code = 97
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char = h;code = 104
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char = C;code = 67
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char = i;code = 105
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char = r;code = 114
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char = l;code = 108
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char = ;code = 32
char = w;code = 119
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char = t;code = 116
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char = ;code = 32
char = (;code = 40
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char = a;code = 97
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char = e;code = 101
char = d;code = 100
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char = b;code = 98
char = y;code = 121
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char = S;code = 83
char = p;code = 112
char = e;code = 101
char = a;code = 97
char = r;code = 114
char = m;code = 109
char = a;code = 97
char = n;code = 110
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char = c;code = 99
char = o;code = 111
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char = r;code = 114
char = e;code = 101
char = l;code = 108
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
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char = n;code = 110
char = a;code = 97
char = l;code = 108
char = y;code = 121
char = s;code = 115
char = i;code = 105
char = s;code = 115
char = .;code = 46
char = ;code = 32
char = T;code = 84
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = l;code = 108
char = a;code = 97
char = r;code = 114
char = g;code = 103
char = e;code = 101
char = s;code = 115
char = t;code = 116
char = ;code = 32
char = A;code = 65
char = U;code = 85
char = C;code = 67
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = R;code = 82
char = O;code = 79
char = C;code = 67
char = ;code = 32
char = c;code = 99
char = u;code = 117
char = r;code = 114
char = v;code = 118
char = e;code = 101
char = ;code = 32
char = w;code = 119
char = a;code = 97
char = s;code = 115
char = ;code = 32
char = o;code = 111
char = b;code = 98
char = t;code = 116
char = a;code = 97
char = i;code = 105
char = n;code = 110
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = T;code = 84
char = C;code = 67
char = /;code = 47
char = H;code = 72
char = D;code = 68
char = L;code = 76
char = -;code = 45
char = C;code = 67
char = ;code = 32
char = r;code = 114
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = ;code = 32
char = a;code = 97
char = s;code = 115
char = ;code = 32
char = o;code = 111
char = n;code = 110
char = e;code = 101
char = ;code = 32
char = p;code = 112
char = a;code = 97
char = r;code = 114
char = a;code = 97
char = m;code = 109
char = e;code = 101
char = t;code = 116
char = e;code = 101
char = r;code = 114
char = .;code = 46
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = C;code = 67
char = O;code = 79
char = N;code = 78
char = C;code = 67
char = L;code = 76
char = U;code = 85
char = S;code = 83
char = I;code = 73
char = O;code = 79
char = N;code = 78
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
char = b;code = 98
char = >;code = 62
char = T;code = 84
char = C;code = 67
char = /;code = 47
char = H;code = 72
char = D;code = 68
char = L;code = 76
char = -;code = 45
char = C;code = 67
char = ;code = 32
char = r;code = 114
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = ,;code = 44
char = ;code = 32
char = T;code = 84
char = G;code = 71
char = /;code = 47
char = H;code = 72
char = D;code = 68
char = L;code = 76
char = -;code = 45
char = C;code = 67
char = ,;code = 44
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char = r;code = 114
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = ,;code = 44
char = ;code = 32
char = N;code = 78
char = o;code = 111
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char = -;code = 45
char = H;code = 72
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char = L;code = 76
char = -;code = 45
char = C;code = 67
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char = C;code = 67
char = ,;code = 44
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char = G;code = 71
char = ,;code = 44
char = ;code = 32
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char = d;code = 100
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char = T;code = 84
char = C;code = 67
char = ;code = 32
char = c;code = 99
char = a;code = 97
char = n;code = 110
char = ;code = 32
char = b;code = 98
char = e;code = 101
char = ;code = 32
char = u;code = 117
char = s;code = 115
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = a;code = 97
char = s;code = 115
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = m;code = 109
char = a;code = 97
char = r;code = 114
char = k;code = 107
char = e;code = 101
char = r;code = 114
char = s;code = 115
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = s;code = 115
char = u;code = 117
char = l;code = 108
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = s;code = 115
char = i;code = 105
char = s;code = 115
char = t;code = 116
char = a;code = 97
char = n;code = 110
char = c;code = 99
char = e;code = 101
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = C;code = 67
char = V;code = 86
char = D;code = 68
char = ;code = 32
char = r;code = 114
char = i;code = 105
char = s;code = 115
char = k;code = 107
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = T;code = 84
char = 2;code = 50
char = D;code = 68
char = ;code = 32
char = p;code = 112
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = s;code = 115
char = .;code = 46
result sql = BACKGROUND : The fasting serum total cholesterol (TC), triglycerides (TG), high density lipoprotein (HDL-C) and low density lipoprotein (LDL-C) levels are used to calculate following lipid ratios: TC/ HDL-C, TG/HDL-C, and LDL-C/HDL-C. Cholesterol retention fraction (CRF), non-HDL-C, LDL-C, TG and waist circumference (WC) one considered as markers for the identification of individuals with an increased risk for cardiovascular diseases (CVD). These individuals frequently show insulin resistance as well. We analyzed the association of lipoprotein ratios with the homeostasis model assessment of insulin resistance (HOMA-IR).

METHODS : Type 2 diabetes mellitus (T2D) patients (92) and 40 age match healthy controls were randomized from the Tapho Primary Health Care Unit and the area in the same district. The HOMA-IR was used to calculate for insulin resistance. The areas under the curves (AUC) of the receiver operating characteristic curves (ROC) were used to compare the power of these serum lipoprotein ratios markers.

RESULTS : All lipoprotein ratios, lipid profile, blood pressure, and WC were significantly higher in T2D patients as compared to healthy controls (P<0.05). TC/HDL-C ratio, TG/HDL-C ratio, non-HDL-C, WC, TG, and TC were significantly correlated with HOMA-IR (P<0.05) as obtained by Spearman correlation analysis. The largest AUC of the ROC curve was obtained with the TC/HDL-C ratio as one parameter.

CONCLUSION : TC/HDL-C ratio, TG/HDL-C, ratio, Non-HDL-C, WC, TG, and TC can be used as the markers of insulin resistance and CVD risk in T2D patients.

Publication: Indian J. Med. Res. 2010 May ;131:641-8.
Publication Date: 2010 May
Study Author(s): Tangvarasittichai, Surapon;Poonsub, Prapaporn;Tangvarasittichai, Orathai;
Institution: Chronic Disease Research Center, Department of Medical Technology, Faculty of Allied Health Sciences, Naresuan University & Buddhachinaraj Hospital, Phitsanulok, Thailand. [email protected]
Shortcut link to this study:
BACKGROUND : The fasting serum total cholesterol (TC), triglycerides (TG), high density lipoprotein (HDL-C) and low density lipoprotein (LDL-C) levels are used to calculate following lipid ratios: TC/ HDL-C, TG/HDL-C, and LDL-C/HDL-C. Cholesterol retention fraction (CRF), non-HDL-C, LDL-C, TG and waist circumference (WC) one considered as markers for the identification of individuals with an increased risk for cardiovascular diseases (CVD). These individuals frequently show insulin resistance as well. We analyzed the association of lipoprotein ratios with the homeostasis model assessment of insulin resistance (HOMA-IR).

METHODS : Type 2 diabetes mellitus (T2D) patients (92) and 40 age match healthy controls were randomized from the Tapho Primary Health Care Unit and the area in the same district. The HOMA-IR was used to calculate for insulin resistance. The areas under the curves (AUC) of the receiver operating characteristic curves (ROC) were used to compare the power of these serum lipoprotein ratios markers.

RESULTS : All lipoprotein ratios, lipid profile, blood pressure, and WC were significantly higher in T2D patients as compared to healthy controls (P<0.05). TC/HDL-C ratio, TG/HDL-C ratio, non-HDL-C, WC, TG, and TC were significantly correlated with HOMA-IR (P<0.05) as obtained by Spearman correlation analysis. The largest AUC of the ROC curve was obtained with the TC/HDL-C ratio as one parameter.

CONCLUSION : TC/HDL-C ratio, TG/HDL-C, ratio, Non-HDL-C, WC, TG, and TC can be used as the markers of insulin resistance and CVD risk in T2D patients.
PMID: 20516535

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