|
|
char = L;code = 76
char = i;code = 105
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char = o;code = 111
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char = c;code = 99
char = ;code = 32
char = a;code = 97
char = c;code = 99
char = i;code = 105
char = d;code = 100
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char = s;code = 115
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char = a;code = 97
char = s;code = 115
char = s;code = 115
char = o;code = 111
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char = i;code = 105
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char = t;code = 116
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char = i;code = 105
char = t;code = 116
char = h;code = 104
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char = e;code = 101
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char = l;code = 108
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char = n;code = 110
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char = n;code = 110
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char = 6;code = 54
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = n;code = 110
char = -;code = 45
char = 3;code = 51
char = ;code = 32
char = f;code = 102
char = a;code = 97
char = t;code = 116
char = t;code = 116
char = y;code = 121
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char = a;code = 97
char = c;code = 99
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char = ;code = 32
char = b;code = 98
char = l;code = 108
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char = l;code = 108
char = l;code = 108
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char = l;code = 108
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char = p;code = 112
char = i;code = 105
char = d;code = 100
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char = a;code = 97
char = n;code = 110
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char = ;code = 32
char = w;code = 119
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char = m;code = 109
char = e;code = 101
char = n;code = 110
char = .;code = 46
result sql = Linoleic acid is associated with lower long-chain n-6 and n-3 fatty acids in red blood cell lipids of Canadian pregnant women.
Linoleic acid is associated with lower long-chain n-6 and n-3 fatty acids in red blood cell lipids of Canadian pregnant women.char = <;code = 60
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char = >;code = 62
char = B;code = 66
char = A;code = 65
char = C;code = 67
char = K;code = 75
char = G;code = 71
char = R;code = 82
char = O;code = 79
char = U;code = 85
char = N;code = 78
char = D;code = 68
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
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char = A;code = 65
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char = a;code = 97
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char = h;code = 104
char = i;code = 105
char = d;code = 100
char = o;code = 111
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char = c;code = 99
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char = (;code = 40
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char = R;code = 82
char = A;code = 65
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char = ,;code = 44
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char = s;code = 115
char = a;code = 97
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char = e;code = 101
char = n;code = 110
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char = a;code = 97
char = e;code = 101
char = n;code = 110
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char = i;code = 105
char = c;code = 99
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char = (;code = 40
char = E;code = 69
char = P;code = 80
char = A;code = 65
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char = x;code = 120
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char = c;code = 99
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char = (;code = 40
char = D;code = 68
char = H;code = 72
char = A;code = 65
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char = ;code = 32
char = a;code = 97
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char = d;code = 100
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char = ;code = 32
char = a;code = 97
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char = e;code = 101
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char = i;code = 105
char = m;code = 109
char = p;code = 112
char = o;code = 111
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char = t;code = 116
char = a;code = 97
char = n;code = 110
char = t;code = 116
char = ;code = 32
char = i;code = 105
char = n;code = 110
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char = m;code = 109
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char = m;code = 109
char = b;code = 98
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char = a;code = 97
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char = e;code = 101
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char = g;code = 103
char = l;code = 108
char = y;code = 121
char = c;code = 99
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char = h;code = 104
char = o;code = 111
char = s;code = 115
char = p;code = 112
char = h;code = 104
char = o;code = 111
char = l;code = 108
char = i;code = 105
char = p;code = 112
char = i;code = 105
char = d;code = 100
char = s;code = 115
char = .;code = 46
char = ;code = 32
char = H;code = 72
char = i;code = 105
char = g;code = 103
char = h;code = 104
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = m;code = 109
char = a;code = 97
char = t;code = 116
char = e;code = 101
char = r;code = 114
char = n;code = 110
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = b;code = 98
char = l;code = 108
char = o;code = 111
char = o;code = 111
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char = A;code = 65
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char = H;code = 72
char = A;code = 65
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char = c;code = 99
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char = c;code = 99
char = e;code = 101
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char = t;code = 116
char = r;code = 114
char = a;code = 97
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char = i;code = 105
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char = ;code = 32
char = i;code = 105
char = n;code = 110
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char = g;code = 103
char = e;code = 101
char = s;code = 115
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char = t;code = 116
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char = o;code = 111
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char = a;code = 97
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char = s;code = 115
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char = t;code = 116
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char = g;code = 103
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char = R;code = 82
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char = P;code = 80
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char = A;code = 65
char = ,;code = 44
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char = ;code = 32
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char = h;code = 104
char = e;code = 101
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char = i;code = 105
char = m;code = 109
char = p;code = 112
char = o;code = 111
char = r;code = 114
char = t;code = 116
char = a;code = 97
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char = c;code = 99
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char = ;code = 32
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char = l;code = 108
char = ;code = 32
char = f;code = 102
char = a;code = 97
char = t;code = 116
char = t;code = 116
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char = c;code = 99
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char = a;code = 97
char = t;code = 116
char = u;code = 117
char = s;code = 115
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char = i;code = 105
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char = a;code = 97
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char = i;code = 105
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char = .;code = 46
char = ;code = 32
char = A;code = 65
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char = i;code = 105
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char = ,;code = 44
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char = d;code = 100
char = ;code = 32
char = c;code = 99
char = e;code = 101
char = l;code = 108
char = l;code = 108
char = ;code = 32
char = (;code = 40
char = R;code = 82
char = B;code = 66
char = C;code = 67
char = );code = 41
char = ;code = 32
char = e;code = 101
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char = h;code = 104
char = a;code = 97
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char = o;code = 111
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char = (;code = 40
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char = P;code = 80
char = G;code = 71
char = s;code = 115
char = );code = 41
char = ;code = 32
char = a;code = 97
char = r;code = 114
char = e;code = 101
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char = h;code = 104
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char = g;code = 103
char = h;code = 104
char = ;code = 32
char = i;code = 105
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char = a;code = 97
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char = m;code = 109
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char = l;code = 108
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char = R;code = 82
char = A;code = 65
char = ,;code = 44
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char = A;code = 65
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char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
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char = <;code = 60
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char = ;code = 32
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char = g;code = 103
char = a;code = 97
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char = t;code = 116
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char = <;code = 60
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char = /;code = 47
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char = <;code = 60
char = b;code = 98
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char = E;code = 69
char = S;code = 83
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char = G;code = 71
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char = ;code = 32
char = :;code = 58
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char = t;code = 116
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char = s;code = 115
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char = r;code = 114
char = e;code = 101
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char = e;code = 101
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char = o;code = 111
char = d;code = 100
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char = <;code = 60
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char = <;code = 60
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char = R;code = 82
char = E;code = 69
char = S;code = 83
char = U;code = 85
char = L;code = 76
char = T;code = 84
char = S;code = 83
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
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char = H;code = 72
char = A;code = 65
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char = a;code = 97
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char = P;code = 80
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char = v;code = 118
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char = s;code = 115
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char = t;code = 116
char = h;code = 104
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char = R;code = 82
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char = C;code = 67
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char = E;code = 69
char = P;code = 80
char = G;code = 71
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char = a;code = 97
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char = o;code = 111
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char = h;code = 104
char = a;code = 97
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char = c;code = 99
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char = A;code = 65
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char = <;code = 60
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char = 0;code = 48
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char = 2;code = 50
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char = 0;code = 48
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char = C;code = 67
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char = G;code = 71
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char = 2;code = 50
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char = 0;code = 48
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char = .;code = 46
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char = A;code = 65
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char = C;code = 67
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char = S;code = 83
char = I;code = 73
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char = E;code = 69
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result sql = BACKGROUND : Arachidonic (ARA), eicosapentaenoic (EPA), and docosahexaenoic (DHA) acids are important in membrane glycerophospholipids. Higher maternal blood ARA, EPA, and DHA concentrations in gestation are associated with higher maternal-to-fetal transfer of ARA, EPA, and DHA, respectively, which emphasizes the importance of maternal fatty acid status in gestation. As in the brain, red blood cell (RBC) ethanolamine phosphoglycerides (EPGs) are high in plasmalogen, ARA, and DHA.
OBJECTIVE : We determined the relation between dietary n-6 (omega-6) and n-3 (omega-3) fatty acid intakes and n-6 and n-3 fatty acids in RBC EPGs and phosphatidylcholine in near-term pregnant women.
DESIGN : The subjects were 105 healthy Canadian pregnant (36 wk gestation) women. Fatty acid intakes were estimated by food-frequency questionnaire, and fasting venous blood samples were collected.
RESULTS : DHA and EPA intakes were positively associated with RBC EPG and phosphatidylcholine concentrations of DHA (rho = 0.309 and 0.369, respectively; P < 0.001) and EPA (rho = 0.391 and 0.228, respectively; P < 0.001) and inversely associated with RBC EPG 22:4n-6 and 22:5n-6 (P < 0.001). In RBCs, concentrations of linoleic acid (LA, 18:2n-6) were inversely associated with DHA, EPA, and ARA, respectively, in EPGs (r = -0.432, P < 0.01; r = -0.201, P < 0.04; and r = -0.303, P < 0.01) and phosphatidylcholine (r = -0.460, -0.490, and -0.604; P < 0.01 for all).
CONCLUSIONS : Membrane fatty acids are influenced by the amount and balance of fatty acid substrates. Our results suggest the competitive interaction of LA with ARA, EPA, and DHA, with no evidence that higher LA increases ARA. Biochemical indicators to suggest that DHA is limiting are present in our population. This trial was registered at clinicaltrials.gov as NCT00620672.
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result sql = Linoleic acid is associated with lower long-chain n-6 and n-3 fatty acids in red blood cell lipids of Canadian pregnant women.
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char = a;code = 97
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char = a;code = 97
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char = t;code = 116
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char = n;code = 110
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char = f;code = 102
char = a;code = 97
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char = t;code = 116
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char = a;code = 97
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char = d;code = 100
char = s;code = 115
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char = i;code = 105
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char = ;code = 32
char = R;code = 82
char = B;code = 66
char = C;code = 67
char = ;code = 32
char = E;code = 69
char = P;code = 80
char = G;code = 71
char = s;code = 115
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char = a;code = 97
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char = a;code = 97
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char = i;code = 105
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char = n;code = 110
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char = a;code = 97
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char = a;code = 97
char = n;code = 110
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char = w;code = 119
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char = >;code = 62
char = <;code = 60
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char = r;code = 114
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char = <;code = 60
char = b;code = 98
char = >;code = 62
char = D;code = 68
char = E;code = 69
char = S;code = 83
char = I;code = 73
char = G;code = 71
char = N;code = 78
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
char = b;code = 98
char = >;code = 62
char = T;code = 84
char = h;code = 104
char = e;code = 101
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char = s;code = 115
char = u;code = 117
char = b;code = 98
char = j;code = 106
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char = e;code = 101
char = r;code = 114
char = e;code = 101
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char = 1;code = 49
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char = h;code = 104
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char = a;code = 97
char = l;code = 108
char = t;code = 116
char = h;code = 104
char = y;code = 121
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char = C;code = 67
char = a;code = 97
char = n;code = 110
char = a;code = 97
char = d;code = 100
char = i;code = 105
char = a;code = 97
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char = p;code = 112
char = r;code = 114
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char = g;code = 103
char = n;code = 110
char = a;code = 97
char = n;code = 110
char = t;code = 116
char = ;code = 32
char = (;code = 40
char = 3;code = 51
char = 6;code = 54
char = ;code = 32
char = w;code = 119
char = k;code = 107
char = ;code = 32
char = g;code = 103
char = e;code = 101
char = s;code = 115
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char = a;code = 97
char = t;code = 116
char = i;code = 105
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char = n;code = 110
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char = ;code = 32
char = w;code = 119
char = o;code = 111
char = m;code = 109
char = e;code = 101
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char = .;code = 46
char = ;code = 32
char = F;code = 70
char = a;code = 97
char = t;code = 116
char = t;code = 116
char = y;code = 121
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char = a;code = 97
char = c;code = 99
char = i;code = 105
char = d;code = 100
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char = i;code = 105
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char = a;code = 97
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char = s;code = 115
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char = w;code = 119
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char = r;code = 114
char = e;code = 101
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char = e;code = 101
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char = a;code = 97
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char = e;code = 101
char = d;code = 100
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char = b;code = 98
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char = f;code = 102
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char = d;code = 100
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char = e;code = 101
char = q;code = 113
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char = e;code = 101
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char = e;code = 101
char = s;code = 115
char = t;code = 116
char = i;code = 105
char = o;code = 111
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char = f;code = 102
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char = e;code = 101
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char = s;code = 115
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char = b;code = 98
char = l;code = 108
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char = a;code = 97
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char = p;code = 112
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char = e;code = 101
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char = e;code = 101
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char = e;code = 101
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char = l;code = 108
char = e;code = 101
char = c;code = 99
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char = e;code = 101
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char = .;code = 46
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char = <;code = 60
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char = >;code = 62
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = R;code = 82
char = E;code = 69
char = S;code = 83
char = U;code = 85
char = L;code = 76
char = T;code = 84
char = S;code = 83
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
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char = H;code = 72
char = A;code = 65
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char = a;code = 97
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char = P;code = 80
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char = C;code = 67
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char = G;code = 71
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char = A;code = 65
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char = 0;code = 48
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char = E;code = 69
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char = <;code = 60
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char = 0;code = 48
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char = C;code = 67
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char = E;code = 69
char = P;code = 80
char = G;code = 71
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char = 2;code = 50
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char = 0;code = 48
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char = .;code = 46
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result sql = BACKGROUND : Arachidonic (ARA), eicosapentaenoic (EPA), and docosahexaenoic (DHA) acids are important in membrane glycerophospholipids. Higher maternal blood ARA, EPA, and DHA concentrations in gestation are associated with higher maternal-to-fetal transfer of ARA, EPA, and DHA, respectively, which emphasizes the importance of maternal fatty acid status in gestation. As in the brain, red blood cell (RBC) ethanolamine phosphoglycerides (EPGs) are high in plasmalogen, ARA, and DHA.
OBJECTIVE : We determined the relation between dietary n-6 (omega-6) and n-3 (omega-3) fatty acid intakes and n-6 and n-3 fatty acids in RBC EPGs and phosphatidylcholine in near-term pregnant women.
DESIGN : The subjects were 105 healthy Canadian pregnant (36 wk gestation) women. Fatty acid intakes were estimated by food-frequency questionnaire, and fasting venous blood samples were collected.
RESULTS : DHA and EPA intakes were positively associated with RBC EPG and phosphatidylcholine concentrations of DHA (rho = 0.309 and 0.369, respectively; P < 0.001) and EPA (rho = 0.391 and 0.228, respectively; P < 0.001) and inversely associated with RBC EPG 22:4n-6 and 22:5n-6 (P < 0.001). In RBCs, concentrations of linoleic acid (LA, 18:2n-6) were inversely associated with DHA, EPA, and ARA, respectively, in EPGs (r = -0.432, P < 0.01; r = -0.201, P < 0.04; and r = -0.303, P < 0.01) and phosphatidylcholine (r = -0.460, -0.490, and -0.604; P < 0.01 for all).
CONCLUSIONS : Membrane fatty acids are influenced by the amount and balance of fatty acid substrates. Our results suggest the competitive interaction of LA with ARA, EPA, and DHA, with no evidence that higher LA increases ARA. Biochemical indicators to suggest that DHA is limiting are present in our population. This trial was registered at clinicaltrials.gov as NCT00620672.
Publication: Am. J. Clin. Nutr. 2010 Jan ;91(1)::23-31.
Publication Date: 2010 Jan
Study Author(s): Friesen, Russell W;Innis, Sheila M;
Institution: Nutrition and Metabolism Program, Child and Family Research Institute, Department of Paediatrics, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Shortcut link to this study:
Publication Date: 2010 Jan
Study Author(s): Friesen, Russell W;Innis, Sheila M;
Institution: Nutrition and Metabolism Program, Child and Family Research Institute, Department of Paediatrics, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Shortcut link to this study:
BACKGROUND : Arachidonic (ARA), eicosapentaenoic (EPA), and docosahexaenoic (DHA) acids are important in membrane glycerophospholipids. Higher maternal blood ARA, EPA, and DHA concentrations in gestation are associated with higher maternal-to-fetal transfer of ARA, EPA, and DHA, respectively, which emphasizes the importance of maternal fatty acid status in gestation. As in the brain, red blood cell (RBC) ethanolamine phosphoglycerides (EPGs) are high in plasmalogen, ARA, and DHA.
OBJECTIVE : We determined the relation between dietary n-6 (omega-6) and n-3 (omega-3) fatty acid intakes and n-6 and n-3 fatty acids in RBC EPGs and phosphatidylcholine in near-term pregnant women.
DESIGN : The subjects were 105 healthy Canadian pregnant (36 wk gestation) women. Fatty acid intakes were estimated by food-frequency questionnaire, and fasting venous blood samples were collected.
RESULTS : DHA and EPA intakes were positively associated with RBC EPG and phosphatidylcholine concentrations of DHA (rho = 0.309 and 0.369, respectively; P < 0.001) and EPA (rho = 0.391 and 0.228, respectively; P < 0.001) and inversely associated with RBC EPG 22:4n-6 and 22:5n-6 (P < 0.001). In RBCs, concentrations of linoleic acid (LA, 18:2n-6) were inversely associated with DHA, EPA, and ARA, respectively, in EPGs (r = -0.432, P < 0.01; r = -0.201, P < 0.04; and r = -0.303, P < 0.01) and phosphatidylcholine (r = -0.460, -0.490, and -0.604; P < 0.01 for all).
CONCLUSIONS : Membrane fatty acids are influenced by the amount and balance of fatty acid substrates. Our results suggest the competitive interaction of LA with ARA, EPA, and DHA, with no evidence that higher LA increases ARA. Biochemical indicators to suggest that DHA is limiting are present in our population. This trial was registered at clinicaltrials.gov as NCT00620672.
OBJECTIVE : We determined the relation between dietary n-6 (omega-6) and n-3 (omega-3) fatty acid intakes and n-6 and n-3 fatty acids in RBC EPGs and phosphatidylcholine in near-term pregnant women.
DESIGN : The subjects were 105 healthy Canadian pregnant (36 wk gestation) women. Fatty acid intakes were estimated by food-frequency questionnaire, and fasting venous blood samples were collected.
RESULTS : DHA and EPA intakes were positively associated with RBC EPG and phosphatidylcholine concentrations of DHA (rho = 0.309 and 0.369, respectively; P < 0.001) and EPA (rho = 0.391 and 0.228, respectively; P < 0.001) and inversely associated with RBC EPG 22:4n-6 and 22:5n-6 (P < 0.001). In RBCs, concentrations of linoleic acid (LA, 18:2n-6) were inversely associated with DHA, EPA, and ARA, respectively, in EPGs (r = -0.432, P < 0.01; r = -0.201, P < 0.04; and r = -0.303, P < 0.01) and phosphatidylcholine (r = -0.460, -0.490, and -0.604; P < 0.01 for all).
CONCLUSIONS : Membrane fatty acids are influenced by the amount and balance of fatty acid substrates. Our results suggest the competitive interaction of LA with ARA, EPA, and DHA, with no evidence that higher LA increases ARA. Biochemical indicators to suggest that DHA is limiting are present in our population. This trial was registered at clinicaltrials.gov as NCT00620672.
PMID: 19923368
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