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char = y;code = 121
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char = l;code = 108
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char = t;code = 116
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char = i;code = 105
char = a;code = 97
char = l;code = 108
char = .;code = 46
result sql = The use of senna with docusate for postoperative constipation after pelvic reconstructive surgery: a randomized, double-blind, placebo-controlled trial.
The use of senna with docusate for postoperative constipation after pelvic reconstructive surgery: a randomized, double-blind, placebo-controlled trial.
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char = T;code = 84
char = I;code = 73
char = V;code = 86
char = E;code = 69
char = ;code = 32
char = :;code = 58
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char = <;code = 60
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result sql = OBJECTIVE : The objective of the study was to compare time to first bowel movement (BM) after surgery in subjects randomized to placebo or senna with docusate.

STUDY DESIGN : Ninety-six subjects completed a baseline 7-day bowel diary before and after surgery. After pelvic reconstructive surgery, the subjects were randomized to either placebo (n=45) or senna (8.6 mg) with docusate (50 mg) (n=48). Time to first BM and postoperative use of magnesium citrate were compared.

RESULTS : There was a significant difference in the time to first BM in those receiving senna with docusate vs placebo (3.00+/-1.50 vs 4.05+/-1.50 days; P<.002). More subjects in the placebo group needed to use magnesium citrate to initiate a bowel movement (43.6% vs 7.0%; P<.001).

CONCLUSION : The use of senna with docusate decreases time to first BM in those undergoing pelvic reconstructive surgery compared with placebo. Subjects using senna with docusate are also significantly less likely to use magnesium citrate.

Publication: Am. J. Obstet. Gynecol. 2010 May ;202(5)::479.e1-5. :doi: 10.1016/j.ajog.2010.01.003.
Publication Date: 2010 May
Study Author(s): Patel, Minita;Schimpf, Megan O;O'Sullivan, David M;LaSala, Christine A;
Institution: Division of Urogynecology, Department of Obstetrics and Gynecology, University of Connecticut School of Medicine, Hartford Hospital, Hartford, CT 06106, USA. [email protected]
Shortcut link to this study:
OBJECTIVE : The objective of the study was to compare time to first bowel movement (BM) after surgery in subjects randomized to placebo or senna with docusate.

STUDY DESIGN : Ninety-six subjects completed a baseline 7-day bowel diary before and after surgery. After pelvic reconstructive surgery, the subjects were randomized to either placebo (n=45) or senna (8.6 mg) with docusate (50 mg) (n=48). Time to first BM and postoperative use of magnesium citrate were compared.

RESULTS : There was a significant difference in the time to first BM in those receiving senna with docusate vs placebo (3.00+/-1.50 vs 4.05+/-1.50 days; P<.002). More subjects in the placebo group needed to use magnesium citrate to initiate a bowel movement (43.6% vs 7.0%; P<.001).

CONCLUSION : The use of senna with docusate decreases time to first BM in those undergoing pelvic reconstructive surgery compared with placebo. Subjects using senna with docusate are also significantly less likely to use magnesium citrate.
PMID: 20207340

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