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result sql = Preoperative detection of prostate cancer: a comparison with 11C-choline PET, 18F-fluorodeoxyglucose PET and MR imaging.
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result sql = PURPOSE : To compare (11)C-choline positron emission tomography (C-PET), (18)F-fluorodeoxyglucose PET (FDG-PET), and MR imaging in the preoperative detection of prostate cancer.
MATERIALS AND METHODS : C-PET, FDG-PET, and MR images were obtained in 43 consecutive patients with suspected prostate cancer, and prostate cancers were histopathologically confirmed in 26 patients. Unenhanced T1-weighted, T2-weighted, and gadolinium-enhanced MR images were obtained. C-PET and FDG-PET were conducted 1.5 and 60 minutes after injection of 5.5 and 5.0 MBq/kg tracers, respectively. A nuclear and a genitourinary radiologist retrospectively reviewed PET and MR images at random, respectively, and assigned a confidence level for the presence of prostate cancer using a four-point scale. Diagnostic performance was tested using the McNemar test and receiver operating characteristic curve analysis.
RESULTS : The sensitivity was greater (P < 0.05) with MR (88%) and C-PET (73%) images than with FDG-PET images (31%). The accuracy was greater (P < 0.05) with MR images (88%) than with C-PET (67%) and FDG-PET (53%) images. The area-under-curve value with MR (0.90) was greater than those with C-PET (0.53) and FDG-PET (0.54) images (P < 0.01).
CONCLUSION : MR imaging should be primarily performed in the preoperative detection of prostate cancer. C-PET and FDG-PET did not improve the detection.
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result sql = Preoperative detection of prostate cancer: a comparison with 11C-choline PET, 18F-fluorodeoxyglucose PET and MR imaging.
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char = A;code = 65
char = L;code = 76
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char = A;code = 65
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char = H;code = 72
char = O;code = 79
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char = a;code = 97
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char = e;code = 101
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char = a;code = 97
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char = a;code = 97
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char = l;code = 108
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char = C;code = 67
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result sql = PURPOSE : To compare (11)C-choline positron emission tomography (C-PET), (18)F-fluorodeoxyglucose PET (FDG-PET), and MR imaging in the preoperative detection of prostate cancer.
MATERIALS AND METHODS : C-PET, FDG-PET, and MR images were obtained in 43 consecutive patients with suspected prostate cancer, and prostate cancers were histopathologically confirmed in 26 patients. Unenhanced T1-weighted, T2-weighted, and gadolinium-enhanced MR images were obtained. C-PET and FDG-PET were conducted 1.5 and 60 minutes after injection of 5.5 and 5.0 MBq/kg tracers, respectively. A nuclear and a genitourinary radiologist retrospectively reviewed PET and MR images at random, respectively, and assigned a confidence level for the presence of prostate cancer using a four-point scale. Diagnostic performance was tested using the McNemar test and receiver operating characteristic curve analysis.
RESULTS : The sensitivity was greater (P < 0.05) with MR (88%) and C-PET (73%) images than with FDG-PET images (31%). The accuracy was greater (P < 0.05) with MR images (88%) than with C-PET (67%) and FDG-PET (53%) images. The area-under-curve value with MR (0.90) was greater than those with C-PET (0.53) and FDG-PET (0.54) images (P < 0.01).
CONCLUSION : MR imaging should be primarily performed in the preoperative detection of prostate cancer. C-PET and FDG-PET did not improve the detection.
Publication: J Magn Reson Imaging 2010 May ;31(5)::1151-6. :doi: 10.1002/jmri.22157.
Publication Date: 2010 May
Study Author(s): Watanabe, Haruo;Kanematsu, Masayuki;Kondo, Hiroshi;Kako, Nobuo;Yamamoto, Naoki;Yamada, Toru;Goshima, Satoshi;Hoshi, Hiroaki;Bae, Kyongtae T;
Institution: Department of Radiology, Gifu University Hospital, Gifu, Japan.
Shortcut link to this study:
Publication Date: 2010 May
Study Author(s): Watanabe, Haruo;Kanematsu, Masayuki;Kondo, Hiroshi;Kako, Nobuo;Yamamoto, Naoki;Yamada, Toru;Goshima, Satoshi;Hoshi, Hiroaki;Bae, Kyongtae T;
Institution: Department of Radiology, Gifu University Hospital, Gifu, Japan.
Shortcut link to this study:
PURPOSE : To compare (11)C-choline positron emission tomography (C-PET), (18)F-fluorodeoxyglucose PET (FDG-PET), and MR imaging in the preoperative detection of prostate cancer.
MATERIALS AND METHODS : C-PET, FDG-PET, and MR images were obtained in 43 consecutive patients with suspected prostate cancer, and prostate cancers were histopathologically confirmed in 26 patients. Unenhanced T1-weighted, T2-weighted, and gadolinium-enhanced MR images were obtained. C-PET and FDG-PET were conducted 1.5 and 60 minutes after injection of 5.5 and 5.0 MBq/kg tracers, respectively. A nuclear and a genitourinary radiologist retrospectively reviewed PET and MR images at random, respectively, and assigned a confidence level for the presence of prostate cancer using a four-point scale. Diagnostic performance was tested using the McNemar test and receiver operating characteristic curve analysis.
RESULTS : The sensitivity was greater (P < 0.05) with MR (88%) and C-PET (73%) images than with FDG-PET images (31%). The accuracy was greater (P < 0.05) with MR images (88%) than with C-PET (67%) and FDG-PET (53%) images. The area-under-curve value with MR (0.90) was greater than those with C-PET (0.53) and FDG-PET (0.54) images (P < 0.01).
CONCLUSION : MR imaging should be primarily performed in the preoperative detection of prostate cancer. C-PET and FDG-PET did not improve the detection.
MATERIALS AND METHODS : C-PET, FDG-PET, and MR images were obtained in 43 consecutive patients with suspected prostate cancer, and prostate cancers were histopathologically confirmed in 26 patients. Unenhanced T1-weighted, T2-weighted, and gadolinium-enhanced MR images were obtained. C-PET and FDG-PET were conducted 1.5 and 60 minutes after injection of 5.5 and 5.0 MBq/kg tracers, respectively. A nuclear and a genitourinary radiologist retrospectively reviewed PET and MR images at random, respectively, and assigned a confidence level for the presence of prostate cancer using a four-point scale. Diagnostic performance was tested using the McNemar test and receiver operating characteristic curve analysis.
RESULTS : The sensitivity was greater (P < 0.05) with MR (88%) and C-PET (73%) images than with FDG-PET images (31%). The accuracy was greater (P < 0.05) with MR images (88%) than with C-PET (67%) and FDG-PET (53%) images. The area-under-curve value with MR (0.90) was greater than those with C-PET (0.53) and FDG-PET (0.54) images (P < 0.01).
CONCLUSION : MR imaging should be primarily performed in the preoperative detection of prostate cancer. C-PET and FDG-PET did not improve the detection.
PMID: 20432351
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