char = T;code = 84 char = y;code = 121 char = r;code = 114 char = o;code = 111 char = s;code = 115 char = i;code = 105 char = n;code = 110 char = a;code = 97 char = s;code = 115 char = e;code = 101 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = h;code = 104 char = i;code = 105 char = b;code = 98 char = i;code = 105 char = t;code = 116 char = o;code = 111 char = r;code = 114 char = y;code = 121 char = ;code = 32 char = e;code = 101 char = f;code = 102 char = f;code = 102 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = q;code = 113 char = u;code = 117 char = e;code = 101 char = r;code = 114 char = c;code = 99 char = e;code = 101 char = t;code = 116 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = 4;code = 52 char = ';code = 39 char = -;code = 45 char = O;code = 79 char = -;code = 45 char = &;code = 38 char = #;code = 35 char = 9;code = 57 char = 4;code = 52 char = 6;code = 54 char = ;;code = 59 char = -;code = 45 char = D;code = 68 char = -;code = 45 char = g;code = 103 char = l;code = 108 char = u;code = 117 char = c;code = 99 char = o;code = 111 char = p;code = 112 char = y;code = 121 char = r;code = 114 char = a;code = 97 char = n;code = 110 char = o;code = 111 char = s;code = 115 char = i;code = 105 char = d;code = 100 char = e;code = 101 char = ;code = 32 char = f;code = 102 char = r;code = 114 char = o;code = 111 char = m;code = 109 char = ;code = 32 char = d;code = 100 char = r;code = 114 char = i;code = 105 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = s;code = 115 char = k;code = 107 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = o;code = 111 char = n;code = 110 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = (;code = 40 char = A;code = 65 char = l;code = 108 char = l;code = 108 char = i;code = 105 char = u;code = 117 char = m;code = 109 char = ;code = 32 char = c;code = 99 char = e;code = 101 char = p;code = 112 char = a;code = 97 char = );code = 41 char = .;code = 46 result sql = Tyrosinase inhibitory effect of quercetin 4'-O-β-D-glucopyranoside from dried skin of red onion (Allium cepa).
Tyrosinase inhibitory effect of quercetin 4'-O-β-D-glucopyranoside from dried skin of red onion (Allium cepa).char = I;code = 73 char = n;code = 110 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = ;code = 32 char = e;code = 101 char = f;code = 102 char = f;code = 102 char = o;code = 111 char = r;code = 114 char = t;code = 116 char = ;code = 32 char = t;code = 116 char = o;code = 111 char = ;code = 32 char = f;code = 102 char = i;code = 105 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = a;code = 97 char = ;code = 32 char = n;code = 110 char = e;code = 101 char = w;code = 119 char = ;code = 32 char = w;code = 119 char = h;code = 104 char = i;code = 105 char = t;code = 116 char = e;code = 101 char = n;code = 110 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = ;code = 32 char = a;code = 97 char = g;code = 103 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = ,;code = 44 char = ;code = 32 char = w;code = 119 char = e;code = 101 char = ;code = 32 char = f;code = 102 char = o;code = 111 char = c;code = 99 char = u;code = 117 char = s;code = 115 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = o;code = 111 char = u;code = 117 char = r;code = 114 char = ;code = 32 char = a;code = 97 char = t;code = 116 char = t;code = 116 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = A;code = 65 char = l;code = 108 char = l;code = 108 char = i;code = 105 char = u;code = 117 char = m;code = 109 char = ;code = 32 char = c;code = 99 char = e;code = 101 char = p;code = 112 char = a;code = 97 char = ;code = 32 char = (;code = 40 char = r;code = 114 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = o;code = 111 char = n;code = 110 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = );code = 41 char = .;code = 46 char = ;code = 32 char = B;code = 66 char = a;code = 97 char = s;code = 115 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = b;code = 98 char = i;code = 105 char = o;code = 111 char = l;code = 108 char = o;code = 111 char = g;code = 103 char = i;code = 105 char = c;code = 99 char = a;code = 97 char = l;code = 108 char = l;code = 108 char = y;code = 121 char = ;code = 32 char = g;code = 103 char = u;code = 117 char = i;code = 105 char = d;code = 100 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = f;code = 102 char = r;code = 114 char = a;code = 97 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = u;code = 117 char = s;code = 115 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = ;code = 32 char = m;code = 109 char = u;code = 117 char = s;code = 115 char = h;code = 104 char = r;code = 114 char = o;code = 111 char = o;code = 111 char = m;code = 109 char = ;code = 32 char = t;code = 116 char = y;code = 121 char = r;code = 114 char = o;code = 111 char = s;code = 115 char = i;code = 105 char = n;code = 110 char = a;code = 97 char = s;code = 115 char = e;code = 101 char = ,;code = 44 char = ;code = 32 char = q;code = 113 char = u;code = 117 char = e;code = 101 char = r;code = 114 char = c;code = 99 char = e;code = 101 char = t;code = 116 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = 4;code = 52 char = ';code = 39 char = -;code = 45 char = O;code = 79 char = -;code = 45 char = &;code = 38 char = #;code = 35 char = 9;code = 57 char = 4;code = 52 char = 6;code = 54 char = ;;code = 59 char = -;code = 45 char = D;code = 68 char = -;code = 45 char = g;code = 103 char = l;code = 108 char = u;code = 117 char = c;code = 99 char = o;code = 111 char = p;code = 112 char = y;code = 121 char = r;code = 114 char = a;code = 97 char = n;code = 110 char = o;code = 111 char = s;code = 115 char = i;code = 105 char = d;code = 100 char = e;code = 101 char = ;code = 32 char = w;code = 119 char = a;code = 97 char = s;code = 115 char = ;code = 32 char = i;code = 105 char = s;code = 115 char = o;code = 111 char = l;code = 108 char = a;code = 97 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = f;code = 102 char = r;code = 114 char = o;code = 111 char = m;code = 109 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = d;code = 100 char = r;code = 114 char = i;code = 105 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = s;code = 115 char = k;code = 107 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = A;code = 65 char = .;code = 46 char = ;code = 32 char = c;code = 99 char = e;code = 101 char = p;code = 112 char = a;code = 97 char = .;code = 46 char = ;code = 32 char = Q;code = 81 char = u;code = 117 char = e;code = 101 char = r;code = 114 char = c;code = 99 char = e;code = 101 char = t;code = 116 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = 4;code = 52 char = ';code = 39 char = -;code = 45 char = O;code = 79 char = -;code = 45 char = &;code = 38 char = #;code = 35 char = 9;code = 57 char = 4;code = 52 char = 6;code = 54 char = ;;code = 59 char = -;code = 45 char = D;code = 68 char = -;code = 45 char = g;code = 103 char = l;code = 108 char = u;code = 117 char = c;code = 99 char = o;code = 111 char = p;code = 112 char = y;code = 121 char = r;code = 114 char = a;code = 97 char = n;code = 110 char = o;code = 111 char = s;code = 115 char = i;code = 105 char = d;code = 100 char = e;code = 101 char = ;code = 32 char = s;code = 115 char = h;code = 104 char = o;code = 111 char = w;code = 119 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = t;code = 116 char = y;code = 121 char = r;code = 114 char = o;code = 111 char = s;code = 115 char = i;code = 105 char = n;code = 110 char = a;code = 97 char = s;code = 115 char = e;code = 101 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = h;code = 104 char = i;code = 105 char = b;code = 98 char = i;code = 105 char = t;code = 116 char = o;code = 111 char = r;code = 114 char = y;code = 121 char = ;code = 32 char = a;code = 97 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = i;code = 105 char = t;code = 116 char = y;code = 121 char = ;code = 32 char = u;code = 117 char = s;code = 115 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = ;code = 32 char = L;code = 76 char = -;code = 45 char = t;code = 116 char = y;code = 121 char = r;code = 114 char = o;code = 111 char = s;code = 115 char = i;code = 105 char = n;code = 110 char = e;code = 101 char = ;code = 32 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = L;code = 76 char = -;code = 45 char = D;code = 68 char = O;code = 79 char = P;code = 80 char = A;code = 65 char = ;code = 32 char = a;code = 97 char = s;code = 115 char = ;code = 32 char = a;code = 97 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = b;code = 98 char = s;code = 115 char = t;code = 116 char = r;code = 114 char = a;code = 97 char = t;code = 116 char = e;code = 101 char = ,;code = 44 char = ;code = 32 char = w;code = 119 char = i;code = 105 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = I;code = 73 char = C;code = 67 char = (;code = 40 char = 5;code = 53 char = 0;code = 48 char = );code = 41 char = ;code = 32 char = v;code = 118 char = a;code = 97 char = l;code = 108 char = u;code = 117 char = e;code = 101 char = s;code = 115 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = 4;code = 52 char = .;code = 46 char = 3;code = 51 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = 5;code = 53 char = 2;code = 50 char = .;code = 46 char = 7;code = 55 char = ;code = 32 char = &;code = 38 char = #;code = 35 char = 1;code = 49 char = 8;code = 56 char = 1;code = 49 char = ;;code = 59 char = M;code = 77 char = ,;code = 44 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = s;code = 115 char = p;code = 112 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = e;code = 101 char = l;code = 108 char = y;code = 121 char = .;code = 46 char = ;code = 32 char = B;code = 66 char = a;code = 97 char = s;code = 115 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = s;code = 115 char = u;code = 117 char = l;code = 108 char = t;code = 116 char = s;code = 115 char = ;code = 32 char = o;code = 111 char = b;code = 98 char = t;code = 116 char = a;code = 97 char = i;code = 105 char = n;code = 110 char = e;code = 101 char = d;code = 100 char = ,;code = 44 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = d;code = 100 char = r;code = 114 char = i;code = 105 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = s;code = 115 char = k;code = 107 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = o;code = 111 char = n;code = 110 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = p;code = 112 char = o;code = 111 char = s;code = 115 char = s;code = 115 char = e;code = 101 char = s;code = 115 char = s;code = 115 char = e;code = 101 char = s;code = 115 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = r;code = 114 char = e;code = 101 char = d;code = 100 char = i;code = 105 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = s;code = 115 char = ;code = 32 char = w;code = 119 char = i;code = 105 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = p;code = 112 char = o;code = 111 char = t;code = 116 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = i;code = 105 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = f;code = 102 char = o;code = 111 char = r;code = 114 char = ;code = 32 char = s;code = 115 char = k;code = 107 char = i;code = 105 char = n;code = 110 char = -;code = 45 char = w;code = 119 char = h;code = 104 char = i;code = 105 char = t;code = 116 char = e;code = 101 char = n;code = 110 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = s;code = 115 char = m;code = 109 char = e;code = 101 char = t;code = 116 char = i;code = 105 char = c;code = 99 char = s;code = 115 char = ;code = 32 char = w;code = 119 char = i;code = 105 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = t;code = 116 char = i;code = 105 char = -;code = 45 char = t;code = 116 char = y;code = 121 char = r;code = 114 char = o;code = 111 char = s;code = 115 char = i;code = 105 char = n;code = 110 char = a;code = 97 char = s;code = 115 char = e;code = 101 char = ;code = 32 char = a;code = 97 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = i;code = 105 char = t;code = 116 char = y;code = 121 char = .;code = 46 char = <;code = 60 char = b;code = 98 char = r;code = 114 char = /;code = 47 char = >;code = 62 result sql = In an effort to find a new whitening agent, we focused our attention on Allium cepa (red onion). Based on biologically guided fractionation using mushroom tyrosinase, quercetin 4'-O-β-D-glucopyranoside was isolated from the dried skin of A. cepa. Quercetin 4'-O-β-D-glucopyranoside showed tyrosinase inhibitory activity using L-tyrosine or L-DOPA as a substrate, with IC(50) values of 4.3 and 52.7 µM, respectively. Based on the results obtained, the dried skin of red onion possesses ingredients with potential for skin-whitening cosmetics with anti-tyrosinase activity.
Publication: Nat. Prod. Res. 2011 Feb ;25(3)::256-63. :doi: 10.1080/14786411003754256.
Publication Date: 2011 Feb
Study Author(s): Arung, Enos Tangke;Wijaya Kusuma, Irawan;Shimizu, Kuniyoshi;Kondo, Ryuichiro;
Institution: Department of Forest and Forest Products Sciences, Faculty of Agriculture, Kyushu University, Fukuoka 812-8581, Japan.
Shortcut link to this study:
In an effort to find a new whitening agent, we focused our attention on Allium cepa (red onion). Based on biologically guided fractionation using mushroom tyrosinase, quercetin 4'-O-β-D-glucopyranoside was isolated from the dried skin of A. cepa. Quercetin 4'-O-β-D-glucopyranoside showed tyrosinase inhibitory activity using L-tyrosine or L-DOPA as a substrate, with IC(50) values of 4.3 and 52.7 µM, respectively. Based on the results obtained, the dried skin of red onion possesses ingredients with potential for skin-whitening cosmetics with anti-tyrosinase activity.
PMID: 20635304