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char = e;code = 101
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char = e;code = 101
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char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
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char = p;code = 112
char = r;code = 114
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char = d;code = 100
char = u;code = 117
char = c;code = 99
char = t;code = 116
char = i;code = 105
char = v;code = 118
char = e;code = 101
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char = d;code = 100
char = ;code = 32
char = d;code = 100
char = e;code = 101
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char = e;code = 101
char = l;code = 108
char = o;code = 111
char = p;code = 112
char = m;code = 109
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = s;code = 115
char = a;code = 97
char = f;code = 102
char = e;code = 101
char = t;code = 116
char = y;code = 121
char = ;code = 32
char = e;code = 101
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char = a;code = 97
char = l;code = 108
char = u;code = 117
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = a;code = 97
char = u;code = 117
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = n;code = 110
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char = i;code = 105
char = c;code = 99
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char = M;code = 77
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char = d;code = 100
char = a;code = 97
char = ;code = 32
char = c;code = 99
char = i;code = 105
char = t;code = 116
char = r;code = 114
char = i;code = 105
char = f;code = 102
char = o;code = 111
char = l;code = 108
char = i;code = 105
char = a;code = 97
char = ;code = 32
char = (;code = 40
char = n;code = 110
char = o;code = 111
char = n;code = 110
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char = ;code = 32
char = j;code = 106
char = u;code = 117
char = i;code = 105
char = c;code = 99
char = e;code = 101
char = .;code = 46
result sql = A multigeneration reproductive and developmental safety evaluation of authentic Morinda citrifolia (noni) juice.
A multigeneration reproductive and developmental safety evaluation of authentic Morinda citrifolia (noni) juice.
char = T;code = 84
char = h;code = 104
char = e;code = 101
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char = i;code = 105
char = m;code = 109
char = p;code = 112
char = a;code = 97
char = c;code = 99
char = t;code = 116
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char = f;code = 102
char = ;code = 32
char = M;code = 77
char = o;code = 111
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char = i;code = 105
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char = d;code = 100
char = a;code = 97
char = ;code = 32
char = c;code = 99
char = i;code = 105
char = t;code = 116
char = r;code = 114
char = i;code = 105
char = f;code = 102
char = o;code = 111
char = l;code = 108
char = i;code = 105
char = a;code = 97
char = ;code = 32
char = (;code = 40
char = n;code = 110
char = o;code = 111
char = n;code = 110
char = i;code = 105
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char = ;code = 32
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char = u;code = 117
char = i;code = 105
char = c;code = 99
char = e;code = 101
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char = o;code = 111
char = n;code = 110
char = ;code = 32
char = f;code = 102
char = e;code = 101
char = r;code = 114
char = t;code = 116
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char = l;code = 108
char = i;code = 105
char = t;code = 116
char = y;code = 121
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char = g;code = 103
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char = e;code = 101
char = a;code = 97
char = l;code = 108
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = i;code = 105
char = n;code = 110
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char = t;code = 116
char = h;code = 104
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char = e;code = 101
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char = g;code = 103
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char = a;code = 97
char = t;code = 116
char = i;code = 105
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char = n;code = 110
char = s;code = 115
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = I;code = 73
char = C;code = 67
char = R;code = 82
char = ;code = 32
char = m;code = 109
char = i;code = 105
char = c;code = 99
char = e;code = 101
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char = s;code = 115
char = ;code = 32
char = e;code = 101
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char = l;code = 108
char = u;code = 117
char = a;code = 97
char = t;code = 116
char = e;code = 101
char = d;code = 100
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char = T;code = 84
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char = e;code = 101
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char = a;code = 97
char = u;code = 117
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = i;code = 105
char = c;code = 99
char = i;code = 105
char = t;code = 116
char = y;code = 121
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = s;code = 115
char = o;code = 111
char = u;code = 117
char = r;code = 114
char = c;code = 99
char = e;code = 101
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = n;code = 110
char = o;code = 111
char = n;code = 110
char = i;code = 105
char = ;code = 32
char = j;code = 106
char = u;code = 117
char = i;code = 105
char = c;code = 99
char = e;code = 101
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char = i;code = 105
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char = ;code = 32
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char = h;code = 104
char = i;code = 105
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char = e;code = 101
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char = ;code = 32
char = b;code = 98
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char = ;code = 32
char = c;code = 99
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char = e;code = 101
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char = c;code = 99
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char = a;code = 97
char = l;code = 108
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char = s;code = 115
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = k;code = 107
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char = o;code = 111
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char = i;code = 105
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char = a;code = 97
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char = ;code = 32
char = g;code = 103
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char = l;code = 108
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char = e;code = 101
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char = n;code = 110
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char = p;code = 112
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char = u;code = 117
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char = .;code = 46
char = ;code = 32
char = T;code = 84
char = h;code = 104
char = i;code = 105
char = s;code = 115
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char = e;code = 101
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char = ;code = 32
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char = f;code = 102
char = s;code = 115
char = p;code = 112
char = r;code = 114
char = i;code = 105
char = n;code = 110
char = g;code = 103
char = .;code = 46
char = ;code = 32
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char = h;code = 104
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char = e;code = 101
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char = ;code = 32
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result sql = The impact of Morinda citrifolia (noni) juice on fertility and offspring health in three generations of ICR mice was evaluated. The authenticity of the source of noni juice in this study was determined by chemical analysis of known marker compounds. Mice were supplied with 5% noni juice at gestation (day 0) until weaning (21 days postpartum). This procedure was followed through three generations of offspring. Three generations of control mice were also evaluated. There were no intergroup differences in gestation and fertility indices or malformation rates. However, litter sizes of the noni group in the first (F1),  second (F2), and third (F3) generations were, respectively, 29.3% (P < 0.01), 19.8% (P < 0.01) and 19.6% (P < 0.01) larger than corresponding controls. Despite larger litter sizes, there were no decreases in fetal weight in any generation of the noni group. Further, maternal health and offspring viability in the noni groups were equal to or greater than the controls. The results of this study suggest that authentic noni juice has no adverse effect on fertility and fetal development, consistent with previous two-generation studies of noni fruit from French Polynesia, Indonesia, and Hainan , China. On the contrary, noni juice appears to facilitate pregnancy and fetal development.

Publication: J Toxicol Sci 2011 Jan ;36(1)::81-5.
Publication Date: 2011 Jan
Study Author(s): Wang, Mian-Ying;Hurn, Jenae;Peng, Lin;Nowicki, Diane;Anderson, Gary;
Institution:
Shortcut link to this study:
The impact of Morinda citrifolia (noni) juice on fertility and offspring health in three generations of ICR mice was evaluated. The authenticity of the source of noni juice in this study was determined by chemical analysis of known marker compounds. Mice were supplied with 5% noni juice at gestation (day 0) until weaning (21 days postpartum). This procedure was followed through three generations of offspring. Three generations of control mice were also evaluated. There were no intergroup differences in gestation and fertility indices or malformation rates. However, litter sizes of the noni group in the first (F1),  second (F2), and third (F3) generations were, respectively, 29.3% (P < 0.01), 19.8% (P < 0.01) and 19.6% (P < 0.01) larger than corresponding controls. Despite larger litter sizes, there were no decreases in fetal weight in any generation of the noni group. Further, maternal health and offspring viability in the noni groups were equal to or greater than the controls. The results of this study suggest that authentic noni juice has no adverse effect on fertility and fetal development, consistent with previous two-generation studies of noni fruit from French Polynesia, Indonesia, and Hainan , China. On the contrary, noni juice appears to facilitate pregnancy and fetal development.
PMID: 21297344

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