Scientific studies on Antiprotozoal

Last updated: September 25, 2013
Dicationic phenyl-2,2'-bichalcophenes and analogues as antiprotozoal agents.
Bioorganic & medicinal chemistry

Antiprotozoal activity of sesquiterpenes from jasonia glutinosa.
Pharmaceutical biology

Synthesis and evaluation of dihydroartemisinin and dihydroartemisitene acetal dimers showing anticancer and antiprotozoal activity.
Bioorganic & medicinal chemistry

Indazole N-oxide derivatives as antiprotozoal agents: synthesis, biological evaluation and mechanism of action studies.
Bioorganic & medicinal chemistry

Improved Inhibitors of Trypanothione Reductase by Combination of Motifs: Synthesis, Inhibitory Potency, Binding Mode, and Antiprotozoal Activities.

Synthesis, antiprotozoal, antimicrobial, ß-hematin inhibition, cytotoxicity and methemoglobin (MetHb) formation activities of bis(8-aminoquinolines).
Bioorganic & medicinal chemistry

Diaryl sulfide-based inhibitors of trypanothione reductase: inhibition potency, revised binding mode and antiprotozoal activities.
Organic & biomolecular chemistry

In vitro bactericidal activity of the antiprotozoal drug miltefosine against Streptococcus pneumoniae and other pathogenic streptococci.
Antimicrobial agents and chemotherapy

Pharmacokinetics and metabolism of the prodrug DB289 (2,5-bis[4-(N-methoxyamidino)phenyl]furan monomaleate) in rat and monkey and its conversion to the antiprotozoal/antifungal drug DB75 (2,5-bis(4-guanylphenyl)furan dihydrochloride).
Drug metabolism and disposition: the biological fate of chemicals

Isoflavonoids and other compounds from Psorothamnus arborescens with antiprotozoal activities.
Journal of natural products

Antiprotozoal activity of (8-hydroxymethylen)-trieicosanyl acetate isolated from Senna villosa.
Phytomedicine : international journal of phytotherapy and phytopharmacology

Antiprotozoal activity of 1-phenethyl-4-aminopiperidine derivatives.
Antimicrobial agents and chemotherapy

Design, synthesis and in vitro antiprotozoal activity of benzimidazole-pentamidine hybrids.
Bioorganic & medicinal chemistry letters

Unified QSAR approach to antimicrobials. Part 3: first multi-tasking QSAR model for input-coded prediction, structural back-projection, and complex networks clustering of antiprotozoal compounds.
Bioorganic & medicinal chemistry

Antiprotozoal activities of heterocyclic-substituted xanthones from the marine-derived fungus Chaetomium sp.
Journal of natural products

Viridamides A and B, lipodepsipeptides with antiprotozoal activity from the marine cyanobacterium Oscillatoria nigro-viridis.
Journal of natural products

Synthesis and antiprotozoal evaluation of new N4-(benzyl)spermidyl-linked bis(1,3,5-thiadiazinane-2-thiones).
Archiv der Pharmazie

Antiprotozoal activities determined in vitro and in vivo of certain plant extracts against Histomonas meleagridis, Tetratrichomonas gallinarum and Blastocystis sp.
Parasitology research

Design, synthesis, and in vitro antiprotozoal, antimycobacterial activities of N-{2-[(7-chloroquinolin-4-yl)amino]ethyl}ureas.
Bioorganic & medicinal chemistry

Synthesis and biological evaluation of novel 4-substituted 1-{[4-(10,15,20-triphenylporphyrin-5-yl)phenyl]methylidene}thiosemicarbazides as new class of potential antiprotozoal agents.
Chemistry & biodiversity

Synthesis and antiprotozoal properties of pentamidine congeners bearing the benzofuran motif.
Journal of medicinal chemistry

Antiprotozoal activity of drimane and coloratane sesquiterpenes towards Trypanosoma brucei rhodesiense and Plasmodium falciparum in vitro.
Phytotherapy research : PTR

An unusual dimeric guaianolide with antiprotozoal activity and further sesquiterpene lactones from Eupatoriumperfoliatum.

Antiprotozoal activity of chloroquinoline based chalcones.
European journal of medicinal chemistry

Synthesis and in vitro antiprotozoal evaluation of substituted phenalenone analogues.
Bioorganic & medicinal chemistry

Synthesis and antiprotozoal activity of 2,5-bis[amidinoaryl]thiazoles.
Bioorganic & medicinal chemistry

Chemical composition and antiprotozoal activities of Colombian Lippia spp essential oils and their major components.
Memórias do Instituto Oswaldo Cruz

First synthesis and antiprotozoal activities of divinyl sulfone-modified carbohydrates.
Bioorganic & medicinal chemistry letters

In situ grazing resistance of Vibrio cholerae in the marine environment.
FEMS microbiology ecology

Structural analysis of farnesyl pyrophosphate synthase from parasitic protozoa, a potential chemotherapeutic target.
Infectious disorders drug targets

Antimicrobial, antimalarial, and antileishmanial activities of mono- and bis-quaternary pyridinium compounds.
Chemical biology & drug design

Inhibitory activity of marine sponge-derived natural products against parasitic protozoa.
Marine drugs

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