Studies on Curcumin and cancer

Curcumin induces chemo/radio-sensitization in ovarian cancer cells and Curcumin nanoparticles inhibit ovarian cancer cell growth.
2010 Journal of ovarian research

Androgen responsive and refractory prostate cancer cells exhibit distinct Curcumin regulated transcriptome.
2008 Cancer biology & therapy

Curcumin inhibits lung cancer cell invasion and metastasis through the tumor suppressor HLJ1.
2008 Cancer research

Time- and dose-dependent effects of Curcumin on gene expression in human colon cancer cells.
2004 Journal of carcinogenesis

Polyethylene glycosylated Curcumin conjugate inhibits pancreatic cancer cell growth through inactivation of Jab1.
2009 Molecular pharmacology

Curcumin suppresses constitutive activation of STAT-3 by up-regulating protein inhibitor of activated STAT-3 (PIAS-3) in ovarian and endometrial cancer cells.
2010 Journal of cellular biochemistry

Involvement of Bcl-2 family members, phosphatidylinositol 3'-kinase/AKT and mitochondrial p53 in Curcumin (diferulolylmethane)-induced apoptosis in prostate cancer.
2007 International journal of oncology

Curcumin causes superoxide anion production and p53-independent apoptosis in human colon cancer cells.
2010 Cancer letters

Chemotherapeutic potential of Curcumin for colorectal cancer.
2002 Current pharmaceutical design

Curcumin-induced GADD153 gene up-regulation in human colon cancer cells.
2004 Carcinogenesis

Curcumin induces apoptosis in HCT-116 human colon cancer cells in a p21-independent manner.
2008 Experimental and molecular pathology

Curcumin inhibits the migration and invasion of human A549 lung cancer cells through the inhibition of matrix metalloproteinase-2 and -9 and Vascular Endothelial Growth Factor (VEGF).
2009 Cancer letters

[DLys(6)]-luteinizing hormone releasing hormone-curcumin conjugate inhibits pancreatic cancer cell growth in vitro and in vivo.
2011 International journal of cancer. Journal international du cancer

Therapeutic potential of Curcumin in prostate cancer--V: Interference with the osteomimetic properties of hormone refractory C4-2B prostate cancer cells.
2004 The Prostate

Wilms' tumour gene 1 (WT1) as a target in Curcumin treatment of pancreatic cancer cells.
2009 European journal of cancer (Oxford, England : 1990)

[DLys(6)]-luteinizing hormone releasing hormone-curcumin conjugate inhibits pancreatic cancer cell growth in vitro and in vivo.
2011 International journal of cancer. Journal international du cancer

[DLys(6)]-luteinizing hormone releasing hormone-curcumin conjugate inhibits pancreatic cancer cell growth in vitro and in vivo.
2011 International journal of cancer. Journal international du cancer

[DLys(6)]-luteinizing hormone releasing hormone-curcumin conjugate inhibits pancreatic cancer cell growth in vitro and in vivo.
2011 International journal of cancer. Journal international du cancer

Curcumin inhibition of integrin (alpha6beta4)-dependent breast cancer cell motility and invasion.
2008 Cancer prevention research (Philadelphia, Pa.)

Curcumin-loaded biodegradable polymeric micelles for colon cancer therapy in vitro and in vivo.
2011 Nanoscale

Modulation of the BRCA1 protein and induction of apoptosis in triple negative breast cancer cell lines by the polyphenolic compound curcumin.
2009 Breast cancer : basic and clinical research

Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-kappaB and nuclear factor-kappaB-regulated gene products in IFN-alpha-sensitive and IFN-alpha-resistant human bladder cancer cells.
2007 Molecular cancer therapeutics

Consumption of the putative chemopreventive agent Curcumin by cancer patients: assessment of Curcumin levels in the colorectum and their pharmacodynamic consequences.
2005 Cancer epidemiology, biomarkers & prevention : a publication of the American Association for cancer Research, cosponsored by the American Society of Preventive Oncology

Ectopic expression of Hsp70 confers resistance and silencing its expression sensitizes human colon cancer cells to curcumin-induced apoptosis.
2004 Carcinogenesis

Ectopic expression of Hsp70 confers resistance and silencing its expression sensitizes human colon cancer cells to curcumin-induced apoptosis.
2004 Carcinogenesis

Regulatory effect of the AMPK-COX-2 signaling pathway in curcumin-induced apoptosis in HT-29 colon cancer cells.
2009 Annals of the New York Academy of Sciences

Curcumin inhibits the proteasome activity in human colon cancer cells in vitro and in vivo.
2008 Cancer research

New role of (-)-epicatechin in enhancing the induction of growth inhibition and apoptosis in human lung cancer cells by curcumin.
2010 Cancer prevention research (Philadelphia, Pa.)

An evaluation of the anti-neoplastic activity of Curcumin in prostate cancer cell lines.
2009 International braz j urol : official journal of the Brazilian Society of Urology

Potent growth suppressive activity of Curcumin in human breast cancer cells: Modulation of Wnt/beta-catenin signaling.
2009 Chemico-biological interactions

Induction of apoptosis by Curcumin and its implications for cancer therapy.
2005 Current cancer drug targets

Notch-1 down-regulation by Curcumin is associated with the inhibition of cell growth and the induction of apoptosis in pancreatic cancer cells.
2006 Cancer

Human colon cancer cells lacking Bax resist curcumin-induced apoptosis and Bax requirement is dispensable with ectopic expression of Smac or downregulation of Bcl-XL.
2005 Carcinogenesis

Superoxide anion and proteasomal dysfunction contribute to curcumin-induced paraptosis of malignant breast cancer cells.
2010 Free radical biology & medicine

Expression profiles of apoptotic genes induced by Curcumin in human breast cancer and mammary epithelial cell lines.
2005 Anticancer research

[The inhibitory effect of Curcumin on the growth of human colon cancer cells (HT-29, WiDr) in vitro].
2005 The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi

Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice.
2005 Clinical cancer research : an official journal of the American Association for cancer Research

Curcumin analogues exhibit enhanced growth suppressive activity in human pancreatic cancer cells.
2009 Anti-cancer drugs

Curcumin inhibits cell proliferation of MDA-MB-231 and BT-483 breast cancer cells mediated by down-regulation of NFkappaB, cyclinD and MMP-1 transcription.
2009 Phytomedicine : international journal of phytotherapy and phytopharmacology

Fabrication and characterization of silk fibroin-derived Curcumin nanoparticles for cancer therapy.
2009 International journal of nanomedicine

beta-Cyclodextrin-curcumin self-assembly enhances Curcumin delivery in prostate cancer cells.
2010 Colloids and surfaces. B, Biointerfaces

Injectable sustained release microparticles of curcumin: a new concept for cancer chemoprevention.
2010 Cancer research

Curcumin potentiates the antitumor effects of gemcitabine in an orthotopic model of human bladder cancer through suppression of proliferative and angiogenic biomarkers.
2010 Biochemical pharmacology

Apoptosis of human lung cancer cells by Curcumin mediated through up-regulation of "growth arrest and DNA damage inducible genes 45 and 153".
2010 Biological & pharmaceutical bulletin

Curcumin for chemoprevention of colon cancer.
2007 Cancer letters

Curcumin inhibits cell motility and alters microfilament organization and function in prostate cancer cells.
2004 Cell motility and the cytoskeleton

Liposomal Curcumin with and without oxaliplatin: effects on cell growth, apoptosis, and angiogenesis in colorectal cancer.
2007 Molecular cancer therapeutics

Polymeric nanoparticle-encapsulated Curcumin ("nanocurcumin"): a novel strategy for human cancer therapy.
2007 Journal of nanobiotechnology

Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3.
2004 Oncogene

Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB in breast cancer cells and potentiates the growth inhibitory effect of paclitaxel in a breast cancer nude mice model.
2009 The breast journal

Curcumin suppresses proliferation and invasion in human gastric cancer cells by downregulation of PAK1 activity and cyclin D1 expression.
2009 Cancer biology & therapy

Curcumin-encapsulated MePEG/PCL diblock copolymeric micelles: a novel controlled delivery vehicle for cancer therapy.
2010 Nanomedicine (London, England)

Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF-1R.
2008 International journal of cancer. Journal international du cancer

Induction of apoptosis in human lung cancer cells by curcumin.
2004 Cancer letters

Curcuminoids-cellular uptake by human primary colon cancer cells as quantitated by a sensitive HPLC assay and its relation with the inhibition of proliferation and apoptosis.
2007 Journal of agricultural and food chemistry

Curcumin inhibits telomerase activity in human cancer cell lines.
2006 International journal of molecular medicine

Modulation of the function of the multidrug resistance-linked ATP-binding cassette transporter ABCG2 by the cancer chemopreventive agent curcumin.
2006 Molecular cancer therapeutics

Curcumin-induced apoptosis of human colon cancer colo 205 cells through the production of ROS, Ca2+ and the activation of caspase-3.
2006 Anticancer research

Curcumin [1,7-bis(4-hydroxy-3-methoxyphenyl)-1-6-heptadine-3,5-dione; C21H20O6] sensitizes human prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L-induced apoptosis by suppressing nuclear factor-kappaB via inhibition of the prosurvival Akt signaling pathway.
2007 The Journal of pharmacology and experimental therapeutics

Curcumin targets FOLFOX-surviving colon cancer cells via inhibition of EGFRs and IGF-1R.
2010 Anticancer research

Liposome encapsulation of Curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice.
2009 International journal of cancer. Journal international du cancer

Curcumin Induces Downregulation of E2F4 Expression and Apoptotic Cell Death in HCT116 Human Colon cancer Cells; Involvement of Reactive Oxygen Species.
2010 The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology

Curcumin inhibits proliferation and migration by increasing the Bax to Bcl-2 ratio and decreasing NF-kappaBp65 expression in breast cancer MDA-MB-231 cells.
2009 International journal of molecular medicine

Curcumin upregulates insulin-like growth factor binding protein-5 (IGFBP-5) and C/EBPalpha during oral cancer suppression.
2010 International journal of cancer. Journal international du cancer

Curcumin decreases acid sphingomyelinase activity in colon cancer Caco-2 cells.
2007 Planta medica

Curcumin down regulates smokeless tobacco-induced NF-kappaB activation and COX-2 expression in human oral premalignant and cancer cells.
2006 Toxicology

Effects of Curcumin on bladder cancer cells and development of urothelial tumors in a rat bladder carcinogenesis model.
2008 Cancer letters

Curcumin therapeutic promises and bioavailability in colorectal cancer.
2010 Drugs of today (Barcelona, Spain : 1998)

Curcumin induces apoptosis in human non-small cell lung cancer NCI-H460 cells through ER stress and caspase cascade- and mitochondria-dependent pathways.
2010 Anticancer research

A phase I/II study of gemcitabine-based chemotherapy plus Curcumin for patients with gemcitabine-resistant pancreatic cancer.
2010 Cancer chemotherapy and pharmacology

Curcumin synergizes with resveratrol to inhibit colon cancer.
2009 Nutrition and cancer

Curcumin inhibits COPD-like airway inflammation and lung cancer progression in mice.
2009 Carcinogenesis

Fluorescence study of the curcumin-casein micelle complexation and its application as a drug nanocarrier to cancer cells.
2008 Biomacromolecules

Dietary Curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer.
2002 Cancer research

Chemosensitization of hormone-refractory prostate cancer cells by Curcumin to TRAIL-induced apoptosis.
2005 Journal of experimental therapeutics & oncology

Suppression of protein kinase C and nuclear oncogene expression as possible action mechanisms of cancer chemoprevention by Curcumin.
2004 Archives of pharmacal research

Curcumin sensitizes prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L by inhibiting nuclear factor-kappaB through suppression of IkappaBalpha phosphorylation.
2004 Molecular cancer therapeutics

Curcumin induces c-jun N-terminal kinase-dependent apoptosis in HCT116 human colon cancer cells.
2004 Carcinogenesis

Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products.
2007 Cancer research

Apoptosis-inducing effects of Curcumin derivatives in human bladder cancer cells.
2006 Anti-cancer drugs

Mechanisms of cancer chemoprevention by curcumin.
2001 Proceedings of the National Science Council, Republic of China. Part B, Life sciences

Curcumin potentiates the antitumor effects of Bacillus Calmette-Guerin against bladder cancer through the downregulation of NF-kappaB and upregulation of TRAIL receptors.
2009 Cancer research

Anti cancer effects of curcumin: cycle of life and death.
2008 Cell division

Inhibition of EGFR signaling in human prostate cancer PC-3 cells by combination treatment with beta-phenylethyl isothiocyanate and curcumin.
2006 Carcinogenesis

Curcumin decreases specificity protein expression in bladder cancer cells.
2008 Cancer research

Curcumin in cancer chemoprevention: molecular targets, pharmacokinetics, bioavailability, and clinical trials.
2010 Archiv der Pharmazie

Evaluation of a nanotechnology-based carrier for delivery of Curcumin in prostate cancer cells.
2008 International journal of oncology

Curcumin inhibits MPA-induced secretion of VEGF from T47-D human breast cancer cells.
2008 Menopause (New York, N.Y.)

New Curcumin analogues exhibit enhanced growth-suppressive activity and inhibit AKT and signal transducer and activator of transcription 3 phosphorylation in breast and prostate cancer cells.
2009 Cancer science

Curcumin, demethoxycurcumin and bisdemethoxycurcumin differentially inhibit cancer cell invasion through the down-regulation of MMPs and uPA.
2009 The Journal of nutritional biochemistry

Therapeutic efficacy of curcumin/TRAIL combination regimen for hormone-refractory prostate cancer.
2008 Oncology research

Curcumin as an anti-cancer agent: review of the gap between basic and clinical applications.
2010 Current medicinal chemistry

Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma.
2011 Molecular cancer

Curcumin as a possible lead compound against hormone-independent, multidrug-resistant breast cancer.
2009 Annals of the New York Academy of Sciences

Molecular evidences for the chemosensitizing efficacy of liposomal Curcumin in paclitaxel chemotherapy in mouse models of cervical cancer.
2011 Oncogene

Activation of ATM/Chk1 by Curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells.
2009 British journal of cancer

Curcumin and gemcitabine in patients with advanced pancreatic cancer.
2010 Nutrition and cancer

Curcumin induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by modulating Akt and p38 MAPK.
2007 Cancer biology & therapy

Age-related differential responses to curcumin-induced apoptosis during the initiation of colon cancer in rats.
2009 Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Curcumin as an Anti-Cancer Agent: Review of the Gap between Basic and Clinical Applications.
2009 Current medicinal chemistry

Expression analysis of maspin in invasive ductal carcinoma of breast and modulation of its expression by Curcumin in breast cancer cell lines.
2010 Chemico-biological interactions

Inhibition of cell survival signal protein kinase B/Akt by Curcumin in human prostate cancer cells.
2003 Journal of cellular biochemistry

Preparation and characterization of lyophilised EGG PC liposomes incorporating Curcumin and evaluation of its activity against colorectal cancer cell lines.
2011 Journal of nanoscience and nanotechnology

Ectopic expression of Bcl-XL or Ku70 protects human colon cancer cells (SW480) against curcumin-induced apoptosis while their down-regulation potentiates it.
2004 Carcinogenesis

Growth-inhibitory effects of Curcumin on ovary cancer cells and its mechanisms.
2004 Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban

Growth inhibition and apoptosis inducing mechanisms of Curcumin on human ovarian cancer cell line A2780.
2006 Chinese journal of integrative medicine

Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary Curcumin in HT-29 human colon cancer cells.
2001 Cancer letters

Elimination of Colon cancer Stem-Like Cells by the Combination of Curcumin and FOLFOX.
2009 Translational oncology

Curcumin exerts antidifferentiation effect through AMPKalpha-PPAR-gamma in 3T3-L1 adipocytes and antiproliferatory effect through AMPKalpha-COX-2 in cancer cells.
2009 Journal of agricultural and food chemistry

Anti-carcinogenic properties of Curcumin on colorectal cancer.
2010 World journal of gastrointestinal oncology

Bax and Bak genes are essential for maximum apoptotic response by curcumin, a polyphenolic compound and cancer chemopreventive agent derived from turmeric, Curcuma longa.
2007 Carcinogenesis

The effects of Curcumin on the invasiveness of prostate cancer in vitro and in vivo.
2006 Prostate cancer and prostatic diseases

New difluoro Knoevenagel condensates of curcumin, their Schiff bases and copper complexes as proteasome inhibitors and apoptosis inducers in cancer cells.
2009 Pharmaceutical research

Mechanisms of curcumin- and EGF-receptor related protein (ERRP)-dependent growth inhibition of colon cancer cells.
2006 Nutrition and cancer

Anti-proliferative potential of Curcumin in androgen-dependent prostate cancer cells occurs through modulation of the Wingless signaling pathway.
2011 International journal of oncology

The combination of epigallocatechin gallate and Curcumin suppresses ER alpha-breast cancer cell growth in vitro and in vivo.
2008 International journal of cancer. Journal international du cancer

Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary Curcumin in HT-29 human colon cancer cells.
2001 Cancer letters

Inhibition of NFkappaB and pancreatic cancer cell and tumor growth by Curcumin is dependent on specificity protein down-regulation.
2010 The Journal of biological chemistry

Encapsulation of Curcumin in alginate-chitosan-pluronic composite nanoparticles for delivery to cancer cells.
2010 Nanomedicine : nanotechnology, biology, and medicine

Murine prostate cancer inhibition by dietary phytochemicals--curcumin and phenyethylisothiocyanate.
2008 Pharmaceutical research

Curcumin sensitizes human colorectal cancer xenografts in nude mice to gamma-radiation by targeting nuclear factor-kappaB-regulated gene products.
2008 Clinical cancer research : an official journal of the American Association for cancer Research

Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator.
2009 Blood

Constitutive activation of transcription factor AP-1 in cervical cancer and suppression of human papillomavirus (HPV) transcription and AP-1 activity in HeLa cells by curcumin.
2005 International journal of cancer. Journal international du cancer

Curcumin down-regulates AR gene expression and activation in prostate cancer cell lines.
2002 International journal of oncology

Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary Curcumin in HT-29 human colon cancer cells.
2001 Cancer letters

Curcumin down-regulates AR gene expression and activation in prostate cancer cell lines.
2002 International journal of oncology

Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary Curcumin in HT-29 human colon cancer cells.
2001 Cancer letters

Phase I dose escalation trial of docetaxel plus Curcumin in patients with advanced and metastatic breast cancer.
2010 Cancer biology & therapy

Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells.
2006 Carcinogenesis

Curcumin disrupts mitotic spindle structure and induces micronucleation in MCF-7 breast cancer cells.
2002 Mutation research

Beta-catenin-mediated transactivation and cell-cell adhesion pathways are important in Curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells.
2002 Oncogene

Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer.
1999 Cancer research

Effects of the phytochemicals, Curcumin and quercetin, upon azoxymethane-induced colon cancer and 7,12-dimethylbenz[a]anthracene-induced mammary cancer in rats.
1996 Carcinogenesis

Mechanism of inhibition of benzo[a]pyrene-induced forestomach cancer in mice by dietary curcumin.
1998 Carcinogenesis

Hypomethylation effects of curcumin, demethoxycurcumin and bisdemethoxycurcumin on WIF-1 promoter in non-small cell lung cancer cell lines.
2011 Molecular medicine reports

Curcumin, a multi-functional chemopreventive agent, blocks growth of colon cancer cells by targeting beta-catenin-mediated transactivation and cell-cell adhesion pathways.
2004 Journal of molecular histology

Mechanism of inhibition of benzo[a]pyrene-induced forestomach cancer in mice by dietary curcumin.
1998 Carcinogenesis

Curcumin induced modulation of cell cycle and apoptosis in gastric and colon cancer cells.
2001 Anticancer research

Hypomethylation effects of curcumin, demethoxycurcumin and bisdemethoxycurcumin on WIF-1 promoter in non-small cell lung cancer cell lines.
2011 Molecular medicine reports

Sensitivity of bladder cancer cells to Curcumin and its derivatives depends on the extracellular matrix.
2007 Anticancer research

Biologic evaluation of Curcumin and structural derivatives in cancer chemoprevention model systems.
2004 Phytochemistry

Biologic evaluation of Curcumin and structural derivatives in cancer chemoprevention model systems.
2004 Phytochemistry

[Analysis of anti-proliferation of Curcumin on human breast cancer cells and its mechanism].
2003 Zhonghua yi xue za zhi

Antiproliferation and apoptosis induced by Curcumin in human ovarian cancer cells.
2006 Cell biology international

Effects of the phytochemicals, Curcumin and quercetin, upon azoxymethane-induced colon cancer and 7,12-dimethylbenz[a]anthracene-induced mammary cancer in rats.
1996 Carcinogenesis

Synthesis and in vitro/in vivo anti-cancer evaluation of curcumin-loaded chitosan/poly(butyl cyanoacrylate) nanoparticles.
2010 International journal of pharmaceutics

Phase II trial of Curcumin in patients with advanced pancreatic cancer.
2008 Clinical cancer research : an official journal of the American Association for cancer Research

New mechanisms and therapeutic potential of Curcumin for colorectal cancer.
2008 Molecular nutrition & food research

Determination of minimum effective dose and optimal dosing schedule for liposomal Curcumin in a xenograft human pancreatic cancer model.
2009 Anticancer research

Curcumin enhances dasatinib-induced inhibition of growth and transformation of colon cancer cells.
2011 International journal of cancer. Journal international du cancer

The anti-cancer efficacy of Curcumin scrutinized through core signaling pathways in glioblastoma.
2010 International journal of molecular medicine

Curcumin attenuates oxidative damage in animals treated with a renal carcinogen, ferric nitrilotriacetate (Fe-NTA): implications for cancer prevention.
2009 Molecular and cellular biochemistry

Hypomethylation effects of curcumin, demethoxycurcumin and bisdemethoxycurcumin on WIF-1 promoter in non-small cell lung cancer cell lines.
2011 Molecular medicine reports

Curcumin induces down-regulation of EZH2 expression through the MAPK pathway in MDA-MB-435 human breast cancer cells.
2010 European journal of pharmacology

Curcumin downregulates homeobox gene NKX3.1 in prostate cancer cell LNCaP.
2007 Acta pharmacologica Sinica

Effects of the phytochemicals, Curcumin and quercetin, upon azoxymethane-induced colon cancer and 7,12-dimethylbenz[a]anthracene-induced mammary cancer in rats.
1996 Carcinogenesis

Mechanism of inhibition of benzo[a]pyrene-induced forestomach cancer in mice by dietary curcumin.
1998 Carcinogenesis

Proteomics-based approach to elucidate the mechanism of antitumor effect of Curcumin in cervical cancer.
2009 Prostaglandins, leukotrienes, and essential fatty acids

Modulatory effects of Curcumin on multi-drug resistance-associated protein 5 in pancreatic cancer cells.
2010 Cancer chemotherapy and pharmacology

Curcumin counteracts the proliferative effect of estradiol and induces apoptosis in cervical cancer cells.
2011 Molecular and cellular biochemistry

AMPK mediates curcumin-induced cell death in CaOV3 ovarian cancer cells.
2008 Oncology reports

Hypomethylation effects of curcumin, demethoxycurcumin and bisdemethoxycurcumin on WIF-1 promoter in non-small cell lung cancer cell lines.
2011 Molecular medicine reports

Curcumin inhibits cell migration of human colon cancer colo 205 cells through the inhibition of nuclear factor kappa B /p65 and down-regulates cyclooxygenase-2 and matrix metalloproteinase-2 expressions.
2006 Anticancer research

Curcumin inhibits the mammalian target of rapamycin-mediated signaling pathways in cancer cells.
2006 International journal of cancer. Journal international du cancer

Induction of G2/M arrest and inhibition of cyclooxygenase-2 activity by Curcumin in human bladder cancer T24 cells.
2006 Oncology reports

Difluorinated-Curcumin (CDF): A Novel Curcumin Analog is a Potent Inhibitor of Colon cancer Stem-Like Cells.
2010 Pharmaceutical research

Curcumin attenuates EGF-induced AQP3 up-regulation and cell migration in human ovarian cancer cells.
2008 Cancer chemotherapy and pharmacology

Synergistic role of Curcumin with current therapeutics in colorectal cancer: minireview.
2009 Nutrition and cancer

Suppression of interleukin 6 and 8 production in head and neck cancer cells with Curcumin via inhibition of Ikappa beta kinase.
2009 Archives of otolaryngology--head & neck surgery

Curcumin loaded pH-sensitive nanoparticles for the treatment of colon cancer.
2009 Journal of biomedical nanotechnology

Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression.
2005 Cancer letters

Cancer chemopreventive effects of curcumin.
2007 Advances in experimental medicine and biology

Curcumin inhibits constitutive STAT3 phosphorylation in human pancreatic cancer cell lines and downregulation of survivin/BIRC5 gene expression.
2010 Cancer investigation

Curcumin inhibits human lung large cell carcinoma cancer tumour growth in a murine xenograft model.
2010 Phytotherapy research : PTR

[The inhibitory effect of Curcumin on the proliferation of HT-29 colonic cancer cell induced by deoxycholic acid].
2009 Zhonghua nei ke za zhi [Chinese journal of internal medicine]

Multiple molecular targets in cancer chemoprevention by curcumin.
2006 The AAPS journal

Lysophosphatidic acid induces STAT3 phosphorylation and ovarian cancer cell motility: their inhibition by curcumin.
2010 Cancer letters

Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model.
2009 International journal of cancer. Journal international du cancer

Redox modulation and human bile duct cancer inhibition by curcumin.
2010 Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells.
2008 Molecular cancer therapeutics

Curcumin modulates the radiosensitivity of colorectal cancer cells by suppressing constitutive and inducible NF-kappaB activity.
2009 International journal of radiation oncology, biology, physics

Chemopreventive potential of Curcumin in prostate cancer.
2010 Genes & nutrition

Modulation of anti-apoptotic and survival pathways by Curcumin as a strategy to induce apoptosis in cancer cells.
2008 Biochemical pharmacology

Mechanisms for the activity of heterocyclic cyclohexanone Curcumin derivatives in estrogen receptor negative human breast cancer cell lines.
2011 Investigational new drugs

Targeting breast stem cells with the cancer preventive compounds Curcumin and piperine.
2010 Breast cancer research and treatment

Curcumin and Liver Cancer: A Review.
2011 Current pharmaceutical biotechnology

Multifunctional role of VIP in prostate cancer progression in a xenograft model: suppression by Curcumin and COX-2 inhibitor NS-398.
2009 Peptides

Therapeutic potential of Curcumin in human prostate cancer. III. Curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivo.
2001 The Prostate

Therapeutic potential of Curcumin in human prostate cancer. II. Curcumin inhibits tyrosine kinase activity of epidermal growth factor receptor and depletes the protein.
2000 Molecular urology

Curcumin mediates ceramide generation via the de novo pathway in colon cancer cells.
2006 Carcinogenesis

A novel monocarbonyl analogue of curcumin, (1E,4E)-1,5-bis(2,3-dimethoxyphenyl)penta-1,4-dien-3-one, induced cancer cell H460 apoptosis via activation of endoplasmic reticulum stress signaling pathway.
2011 Journal of medicinal chemistry

Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines.
2001 Oncogene

In vivo inhibition of nitric oxide synthase gene expression by curcumin, a cancer preventive natural product with anti-inflammatory properties.
1998 Biochemical pharmacology

Curcumin induces apoptosis-independent death in oesophageal cancer cells.
2009 British journal of cancer

Novel anti-prostate cancer Curcumin analogues that enhance androgen receptor degradation activity.
2009 Anti-cancer agents in medicinal chemistry

PAC, a novel Curcumin analogue, has anti-breast cancer properties with higher efficiency on ER-negative cells.
2010 Breast cancer research and treatment

Curcumin: a potential radio-enhancer in head and neck cancer.
2009 The Laryngoscope

Curcumin derivatives: molecular basis of their anti-cancer activity.
2009 Biochemical pharmacology

Curcumin downregulates the inflammatory cytokines CXCL1 and -2 in breast cancer cells via NFkappaB.
2008 Carcinogenesis

Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines.
2001 Oncogene

Curcumin inhibits the side population (SP) phenotype of the rat C6 glioma cell line: towards targeting of cancer stem cells with phytochemicals.
2010 Cancer letters

A novel monocarbonyl analogue of curcumin, (1E,4E)-1,5-bis(2,3-dimethoxyphenyl)penta-1,4-dien-3-one, induced cancer cell H460 apoptosis via activation of endoplasmic reticulum stress signaling pathway.
2011 Journal of medicinal chemistry

The antitumor activities of Curcumin and of its isoxazole analogue are not affected by multiple gene expression changes in an MDR model of the MCF-7 breast cancer cell line: analysis of the possible molecular basis.
2007 International journal of molecular medicine

Upregulation of p53 Expression in Patients with Colorectal cancer by Administration of Curcumin.
2011 Cancer investigation

Curcumin synergizes the growth inhibitory properties of Indian toad (Bufo melanostictus Schneider) skin-derived factor (BM-ANF1) in HCT-116 colon cancer cells.
2009 Anticancer research

Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by Curcumin or its analogue CDF.
2010 Cancer research

Curcumin decreases the expression of Pokemon by suppressing the binding activity of the Sp1 protein in human lung cancer cells.
2010 Molecular biology reports

The chemopreventive polyphenol Curcumin prevents hematogenous breast cancer metastases in immunodeficient mice.
2007 Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Synthesis, oxidant properties, and antitumoral effects of a heteroleptic palladium(II) complex of Curcumin on human prostate cancer cells.
2009 Journal of medicinal chemistry

In vivo inhibition of nitric oxide synthase gene expression by curcumin, a cancer preventive natural product with anti-inflammatory properties.
1998 Biochemical pharmacology

Prevention and treatment of pancreatic cancer by Curcumin in combination with omega-3 fatty acids.
2008 Nutrition and cancer

Synthesis and biological evaluation of novel Curcumin analogs as anti-cancer and anti-angiogenesis agents.
2004 Bioorganic & medicinal chemistry

Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines.
2001 Oncogene

Curcumin induces apoptosis in human breast cancer cells through p53-dependent Bax induction.
2002 FEBS letters

Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines.
2001 Oncogene

A synergistic antiproliferation effect of Curcumin and docosahexaenoic acid in SK-BR-3 breast cancer cells: unique signaling not explained by the effects of either compound alone.
2011 BMC cancer

A novel monocarbonyl analogue of curcumin, (1E,4E)-1,5-bis(2,3-dimethoxyphenyl)penta-1,4-dien-3-one, induced cancer cell H460 apoptosis via activation of endoplasmic reticulum stress signaling pathway.
2011 Journal of medicinal chemistry

A synergistic antiproliferation effect of Curcumin and docosahexaenoic acid in SK-BR-3 breast cancer cells: unique signaling not explained by the effects of either compound alone.
2011 BMC cancer

In vivo inhibition of nitric oxide synthase gene expression by curcumin, a cancer preventive natural product with anti-inflammatory properties.
1998 Biochemical pharmacology

Curcumin-containing diet inhibits diethylnitrosamine-induced murine hepatocarcinogenesis.
2000 Carcinogenesis

The inhibitory effect of curcumin, genistein, quercetin and cisplatin on the growth of oral cancer cells in vitro.
2000 Anticancer research

Suppression of protein kinase C and nuclear oncogene expression as possible molecular mechanisms of cancer chemoprevention by apigenin and curcumin.
1997 Journal of cellular biochemistry. Supplement

Curcumin induces apoptosis in immortalized NIH 3T3 and malignant cancer cell lines.
1996 Nutrition and cancer

Curcumin inhibits interferon-alpha induced NF-kappaB and COX-2 in human A549 non-small cell lung cancer cells.
2005 Biochemical and biophysical research communications

Curcumin induces apoptosis in immortalized NIH 3T3 and malignant cancer cell lines.
1996 Nutrition and cancer

Structure of Curcumin in complex with lipoxygenase and its significance in cancer.
2003 International journal of molecular medicine

The inhibitory effect of curcumin, genistein, quercetin and cisplatin on the growth of oral cancer cells in vitro.
2000 Anticancer research

Osteopontin prevents curcumin-induced apoptosis and promotes survival through Akt activation via alpha v beta 3 integrins in human gastric cancer cells.
2008 Experimental biology and medicine (Maywood, N.J.)

Celecoxib and Curcumin additively inhibit the growth of colorectal cancer in a rat model.
2006 Digestion

Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: apoptotic index as a biomarker in colon cancer chemoprevention and promotion.
1997 Cancer research

Curcumin potentiates the pro-apoptotic effects of sulindac sulfone in colorectal cancer.
2010 Expert opinion on investigational drugs

Curcumin in cancer management: recent results of analogue design and clinical studies and desirable future research.
2008 Molecular nutrition & food research

Chemoprotective mechanism of the natural compounds, epigallocatechin-3-O-gallate, quercetin and Curcumin against cancer and cardiovascular diseases.
2009 Current medicinal chemistry

Curcumin sensitizes lung cancer cells to cisplatin-induced apoptosis through superoxide anion-mediated Bcl-2 degradation.
2009 Cancer investigation

The inhibitory effect of curcumin, genistein, quercetin and cisplatin on the growth of oral cancer cells in vitro.
2000 Anticancer research

Suppression of protein kinase C and nuclear oncogene expression as possible molecular mechanisms of cancer chemoprevention by apigenin and curcumin.
1997 Journal of cellular biochemistry. Supplement

Curcumin and cancer cells: how many ways can curry kill tumor cells selectively?
2009 The AAPS journal

Nicotine-induced survival signaling in lung cancer cells is dependent on their p53 status while its down-regulation by Curcumin is independent.
2010 Molecular cancer

Anti-breast cancer activity of Curcumin on the human oxidation-resistant cells ZR-75-1 with gamma-glutamyltranspeptidase inhibition.
2010 Journal of experimental therapeutics & oncology

Evaluation of Curcumin acetates and amino acid conjugates as proteasome inhibitors.
2010 International journal of molecular medicine

Human colon cancer cells differ in their sensitivity to curcumin-induced apoptosis and heat shock protects them by inhibiting the release of apoptosis-inducing factor and caspases.
2003 FEBS letters

Curcumin induces apoptosis in immortalized NIH 3T3 and malignant cancer cell lines.
1996 Nutrition and cancer

Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: apoptotic index as a biomarker in colon cancer chemoprevention and promotion.
1997 Cancer research

Activation of PPAR{gamma} by Curcumin inhibits Moser cell growth and mediates suppression of gene expression of cyclin D1 and EGFR.
2005 American journal of physiology. Gastrointestinal and liver physiology

Suppression of protein kinase C and nuclear oncogene expression as possible molecular mechanisms of cancer chemoprevention by apigenin and curcumin.
1997 Journal of cellular biochemistry. Supplement

Activation of PPAR{gamma} by Curcumin inhibits Moser cell growth and mediates suppression of gene expression of cyclin D1 and EGFR.
2005 American journal of physiology. Gastrointestinal and liver physiology

The inhibitory effect of curcumin, genistein, quercetin and cisplatin on the growth of oral cancer cells in vitro.
2000 Anticancer research

Curcumin inhibits telomerase activity through human telomerase reverse transcritpase in MCF-7 breast cancer cell line.
2002 Cancer letters

Suppression of protein kinase C and nuclear oncogene expression as possible molecular mechanisms of cancer chemoprevention by apigenin and curcumin.
1997 Journal of cellular biochemistry. Supplement

Curcumin induces apoptosis in immortalized NIH 3T3 and malignant cancer cell lines.
1996 Nutrition and cancer

Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: apoptotic index as a biomarker in colon cancer chemoprevention and promotion.
1997 Cancer research

Combined inhibitory effects of Curcumin and phenethyl isothiocyanate on the growth of human PC-3 prostate xenografts in immunodeficient mice.
2006 Cancer research

EF24, a novel synthetic Curcumin analog, induces apoptosis in cancer cells via a redox-dependent mechanism.
2005 Anti-cancer drugs

Curcumin suppresses human papillomavirus oncoproteins, restores p53, Rb, and PTPN13 proteins and inhibits benzo[a]pyrene-induced upregulation of HPV E7.
2011 Molecular carcinogenesis

Colorectal cancer: chemopreventive role of Curcumin and resveratrol.
2010 Nutrition and cancer

Curcumin and genistein, plant natural products, show synergistic inhibitory effects on the growth of human breast cancer MCF-7 cells induced by estrogenic pesticides.
1997 Biochemical and biophysical research communications

Curcumin and genistein, plant natural products, show synergistic inhibitory effects on the growth of human breast cancer MCF-7 cells induced by estrogenic pesticides.
1997 Biochemical and biophysical research communications

Anticarcinogenic effect of bis-1,7-(2-hydroxyphenyl)-hepta-1,6-diene-3,5-dione a Curcumin analog on DMH-induced colon cancer model.
2003 Pharmacological research : the official journal of the Italian Pharmacological Society

Curcumin reduced the side effects of mitomycin C by inhibiting GRP58-mediated DNA cross-linking in MCF-7 breast cancer xenografts.
2009 Cancer science

Anticancer and carcinogenic properties of curcumin: considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent.
2008 Molecular nutrition & food research

Synthesis of novel biodegradable and self-assembling methoxy poly(ethylene glycol)-palmitate nanocarrier for Curcumin delivery to cancer cells.
2008 Acta biomaterialia

Combined xanthorrhizol-curcumin exhibits synergistic growth inhibitory activity via apoptosis induction in human breast cancer cells MDA-MB-231.
2009 Cancer cell international

Celecoxib and Curcumin synergistically inhibit the growth of colorectal cancer cells.
2005 Clinical cancer research : an official journal of the American Association for cancer Research

Curcumin inhibits neurotensin-mediated interleukin-8 production and migration of HCT116 human colon cancer cells.
2006 Clinical cancer research : an official journal of the American Association for cancer Research

New structural analogues of Curcumin exhibit potent growth suppressive activity in human colorectal carcinoma cells.
2009 BMC cancer

Curcumin and genistein, plant natural products, show synergistic inhibitory effects on the growth of human breast cancer MCF-7 cells induced by estrogenic pesticides.
1997 Biochemical and biophysical research communications

Antitumor agents. 250. Design and synthesis of new Curcumin analogues as potential anti-prostate cancer agents.
2006 Journal of medicinal chemistry

Curcumin impairs tumor suppressor p53 function in colon cancer cells.
2004 Carcinogenesis

Synergism from sequenced combinations of Curcumin and epigallocatechin-3-gallate with cisplatin in the killing of human ovarian cancer cells.
2011 Anticancer research

Synergism from sequenced combinations of Curcumin and epigallocatechin-3-gallate with cisplatin in the killing of human ovarian cancer cells.
2011 Anticancer research

Curcumin inhibits tyrosine kinase activity of p185neu and also depletes p185neu.
1999 Clinical cancer research : an official journal of the American Association for cancer Research

Curcumin inhibits tyrosine kinase activity of p185neu and also depletes p185neu.
1999 Clinical cancer research : an official journal of the American Association for cancer Research

Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: comparison with trichostatin A, sulindac, and Curcumin and implications for chemoprevention of colon cancer.
2000 Cancer research

Curcumin inhibits tyrosine kinase activity of p185neu and also depletes p185neu.
1999 Clinical cancer research : an official journal of the American Association for cancer Research

Chemoprevention of colon cancer by a synthetic Curcumin analog involves amelioration of oxidative stress.
2005 Toxicology mechanisms and methods

Curcumin: from food spice to cancer prevention.
2009 Asian Pacific journal of cancer prevention : APJCP

Curcumin: a novel nutritionally derived ligand of the vitamin D receptor with implications for colon cancer chemoprevention.
2010 The Journal of nutritional biochemistry

Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: comparison with trichostatin A, sulindac, and Curcumin and implications for chemoprevention of colon cancer.
2000 Cancer research

Curcumin inhibits tyrosine kinase activity of p185neu and also depletes p185neu.
1999 Clinical cancer research : an official journal of the American Association for cancer Research

Poly(-cyclodextrin)/curcumin self-assembly: a novel approach to improve Curcumin delivery and its therapeutic efficacy in prostate cancer cells.
2010 Macromolecular bioscience

A new Curcumin derivative, HBC, interferes with the cell cycle progression of colon cancer cells via antagonization of the Ca2+/calmodulin function.
2004 Chemistry & biology

Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: comparison with trichostatin A, sulindac, and Curcumin and implications for chemoprevention of colon cancer.
2000 Cancer research

Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: comparison with trichostatin A, sulindac, and Curcumin and implications for chemoprevention of colon cancer.
2000 Cancer research

A new Curcumin derivative, HBC, interferes with the cell cycle progression of colon cancer cells via antagonization of the Ca2+/calmodulin function.
2004 Chemistry & biology

4-Hydroxy-3-methoxybenzoic acid methyl ester: a Curcumin derivative targets Akt/NF kappa B cell survival signaling pathway: potential for prostate cancer management.
2003 Neoplasia (New York, N.Y.)

RNA Binding Protein CUGBP2/CELF2 Mediates Curcumin-Induced Mitotic Catastrophe of Pancreatic cancer Cells.
2011 PloS one

Curcumin induces the degradation of cyclin E expression through ubiquitin-dependent pathway and up-regulates cyclin-dependent kinase inhibitors p21 and p27 in multiple human tumor cell lines.
2007 Biochemical pharmacology

[Research of anti-proliferation of Curcumin on A549 human lung cancer cells and its mechanism].
2004 Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

Antitumor effects of Curcumin and structurally beta-diketone modified analogs on multidrug resistant cancer cells.
2008 Bioorganic & medicinal chemistry letters

Curcumin analog cytotoxicity against breast cancer cells: exploitation of a redox-dependent mechanism.
2009 Bioorganic & medicinal chemistry letters

Metabolism of Curcumin and induction of mitotic catastrophe in human cancer cells.
2008 Molecular nutrition & food research

Activation of the p38 pathway by a novel monoketone Curcumin analog, EF24, suggests a potential combination strategy.
2010 Biochemical pharmacology

Curcumin polymers as anticancer conjugates.
2010 Biomaterials

Anti-cancer and anti-angiogenic effects of Curcumin and tetrahydrocurcumin on implanted hepatocellular carcinoma in nude mice.
2008 World journal of gastroenterology : WJG

Synthesis of Curcumin analogues as potential antioxidant, cancer chemopreventive agents.
2004 Archiv der Pharmazie

Curcumin enhances cytotoxicity of chemotherapeutic agents in prostate cancer cells by inducing p21(WAF1/CIP1) and C/EBPbeta expressions and suppressing NF-kappaB activation.
2002 The Prostate

[Anti-proliferative and anti-metastatic effects of Curcumin on oral cancer cells].
2011 Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology

Curcumin enhances the apoptosis-inducing potential of TRAIL in prostate cancer cells: molecular mechanisms of apoptosis, migration and angiogenesis.
2007 Journal of molecular signaling

Synthesis, characterization and biological evaluation of succinate prodrugs of curcuminoids for colon cancer treatment.
2011 Molecules (Basel, Switzerland)

[Curcumin-induced the expression of inhibitor kappaBalpha protein in human prostate cancer cells].
2006 Zhonghua wai ke za zhi [Chinese journal of surgery]

Curcumin analogue GO-Y030 inhibits STAT3 activity and cell growth in breast and pancreatic carcinomas.
2009 International journal of oncology

Drugs that target specificity proteins downregulate epidermal growth factor receptor in bladder cancer cells.
2010 Molecular cancer research : MCR

Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer.
2001 Clinical cancer research : an official journal of the American Association for cancer Research

Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer.
2001 Clinical cancer research : an official journal of the American Association for cancer Research

Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer.
2001 Clinical cancer research : an official journal of the American Association for cancer Research

Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer.
2001 Clinical cancer research : an official journal of the American Association for cancer Research

Polyphenols as cancer chemopreventive agents.
1995 Journal of cellular biochemistry. Supplement

Polyphenols as cancer chemopreventive agents.
1995 Journal of cellular biochemistry. Supplement

Extended treatment with physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells.
2007 Molecular cancer therapeutics

Consumption of some polyphenols reduces fecal deoxycholic acid and lithocholic acid, the secondary bile acids of risk factors of colon cancer.
2009 Journal of agricultural and food chemistry

Synthetic curcuminoids modulate the arachidonic acid metabolism of human platelet 12-lipoxygenase and reduce sprout formation of human endothelial cells.
2006 Molecular cancer therapeutics