Scientific studies on Fatty Acid Oxidation

Last updated: September 25, 2013
Fetal fatty acid oxidation defects and maternal liver disease in pregnancy.
Obstetrics and gynecology

A comparison between ranolazine and CVT-4325, a novel inhibitor of fatty acid oxidation, on cardiac metabolism and left ventricular function in rat isolated perfused heart during ischemia and reperfusion.
The Journal of pharmacology and experimental therapeutics

AMPK-independent pathways regulate skeletal muscle fatty acid oxidation.
The Journal of physiology

Activity and mRNA levels of enzymes involved in hepatic fatty acid oxidation in mice fed citrus flavonoids.
Nutrition (Burbank, Los Angeles County, Calif.)

Chronic hexosamine flux stimulates fatty acid oxidation by activating AMP-activated protein kinase in adipocytes.
The Journal of biological chemistry

Mitochondrial fatty acid oxidation disorders: pathophysiological studies in mouse models.
Journal of inherited metabolic disease

Telmisartan increases fatty acid oxidation in skeletal muscle through a peroxisome proliferator-activated receptor-gamma dependent pathway.
Journal of hypertension

Fatty acid oxidation is decreased in the liver of ovariectomized rats.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme

Mitochondrial fatty acid oxidation disorders: clinical presentation of long-chain fatty acid oxidation defects before and after newborn screening.
Journal of inherited metabolic disease

Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha.
The EMBO journal

Leptin stimulates fatty acid oxidation and peroxisome proliferator-activated receptor alpha gene expression in mouse C2C12 myoblasts by changing the subcellular localization of the alpha2 form of AMP-activated protein kinase.
Molecular and cellular biology

Malonyl-CoA decarboxylase is a major regulator of myocardial fatty acid oxidation.
Current hypertension reports

Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells.
Biochimica et biophysica acta

Disease mechanisms and protein structures in fatty acid oxidation defects.
Journal of inherited metabolic disease

Rosiglitazone increases fatty acid oxidation and fatty acid translocase (FAT/CD36) but not carnitine palmitoyltransferase I in rat muscle mitochondria.
The Journal of physiology

FAT/CD36-null mice reveal that mitochondrial FAT/CD36 is required to upregulate mitochondrial fatty acid oxidation in contracting muscle.
American journal of physiology. Regulatory, integrative and comparative physiology

Paradoxical coupling of triglyceride synthesis and fatty acid oxidation in skeletal muscle overexpressing DGAT1.

Isoproterenol stimulates 5'-AMP-activated protein kinase and fatty acid oxidation in neonatal hearts.
American journal of physiology. Heart and circulatory physiology

The interplay of prolactin and the glucocorticoids in the regulation of beta-cell gene expression, fatty acid oxidation, and glucose-stimulated insulin secretion: implications for carbohydrate metabolism in pregnancy.

Myocardial hypertrophy and the maturation of fatty acid oxidation in the newborn human heart.
Pediatric research

Stimulation of cardiac fatty acid oxidation by leptin is mediated by a nitric oxide-p38 MAPK-dependent mechanism.
European journal of pharmacology

Myocardial infarction in rats causes partial impairment in insulin response associated with reduced fatty acid oxidation and mitochondrial gene expression.
The Journal of thoracic and cardiovascular surgery

Lipid metabolism and nutrigenomics - impact of sesame lignans on gene expression profiles and fatty acid oxidation in rat liver.
Forum of nutrition

Treatment recommendations in long-chain fatty acid oxidation defects: consensus from a workshop.
Journal of inherited metabolic disease

Increased glucose uptake and oxidation in mouse hearts prevent high fatty acid oxidation but cause cardiac dysfunction in diet-induced obesity.

Regulation of fatty acid oxidation in chicken (Gallus gallus): interactions between genotype and diet composition.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology

Regulator of G protein signaling (RGS16) inhibits hepatic fatty acid oxidation in a CHREBP-dependent manner.
The Journal of biological chemistry

Tetradecylthioacetic acid attenuates dyslipidaemia in male patients with type 2 diabetes mellitus, possibly by dual PPAR-alpha/delta activation and increased mitochondrial fatty acid oxidation.
Diabetes, obesity & metabolism

The PPAR{beta}/{delta} Activator GW501516 Prevents the Down-Regulation of AMPK Caused by a High-Fat Diet in Liver and Amplifies the PGC-1α-Lipin 1-PPARα Pathway Leading to Increased Fatty Acid Oxidation.

Malonyl CoA control of fatty acid oxidation in the newborn heart in response to increased fatty acid supply.
Canadian journal of physiology and pharmacology

Dietary trans 10, cis 12-conjugated linoleic acid reduces the expression of fatty acid oxidation and drug detoxification enzymes in mouse liver.
The British journal of nutrition

Alpha2-AMPK activity is not essential for an increase in fatty acid oxidation during low-intensity exercise.
American journal of physiology. Endocrinology and metabolism

Long chain fatty acid oxidation defects in children: importance of detection and treatment options.
Irish journal of medical science

Bile acylcarnitine profiles in pediatric liver disease do not interfere with the diagnosis of long-chain fatty acid oxidation defects.
Clinica chimica acta; international journal of clinical chemistry

Fatty acid oxidation inhibitors in the management of chronic complications of atherosclerosis.
Current atherosclerosis reports

Anti-anginal effects of partial fatty acid oxidation inhibitors.
Current opinion in pharmacology

Skeletal muscle group VIA phospholipase A2 (iPLA2beta): expression and role in fatty acid oxidation.

Proteomic analysis of mitochondria reveals a metabolic switch from fatty acid oxidation to glycolysis in the failing heart.
Science in China. Series C, Life sciences / Chinese Academy of Sciences

Heart-type fatty acid-binding protein is essential for efficient brown adipose tissue fatty acid oxidation and cold tolerance.
The Journal of biological chemistry