Scientific studies on sucralose

Last updated: September 25, 2013
Effects of oral ingestion of sucralose on gut hormone response and appetite in healthy normal-weight subjects.
European journal of clinical nutrition

Fate of Sucralose through Environmental and Water Treatment Processes and Impact on Plant Indicator Species.
Environmental science & technology

Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects.
American journal of physiology. Gastrointestinal and liver physiology

Development of a quantitative high-performance thin-layer chromatographic method for sucralose in sewage effluent, surface water, and drinking water.
Journal of chromatography. A

Understanding consumption-related sucralose emissions - A conceptual approach combining substance-flow analysis with sampling analysis.
The Science of the total environment

Determination of sucralose in soft drinks by high-performance thin-layer chromatography: interlaboratory study.
Journal of AOAC International

Neonatal exposure to sucralose does not alter biochemical markers of neuronal development or adult behavior.
Nutrition (Burbank, Los Angeles County, Calif.)

An overview of the safety of sucralose.
Regulatory toxicology and pharmacology : RTP

Effect of the artificial sweetener, sucralose, on small intestinal glucose absorption in healthy human subjects.
The British journal of nutrition

Analysis of sucralose and other sweeteners in water and beverage samples by liquid chromatography/time-of-flight mass spectrometry.
Journal of chromatography. A

Bioconcentration of the intense sweetener sucralose in a multitrophic battery of aquatic organisms.
Environmental toxicology and chemistry / SETAC

The absence of genotoxicity of sucralose.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Sucralose sweetener in vivo effects on blood constituents radiolabeling, red blood cell morphology and radiopharmaceutical biodistribution in rats.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

Pilot study: alleviation of pain in burning mouth syndrome with topical sucralose.

Clinical relevance of measuring colonic permeability.
European journal of clinical investigation

Positive allosteric modulators of the human sweet taste receptor enhance sweet taste.
Proceedings of the National Academy of Sciences of the United States of America

Analysis and occurrence of seven artificial sweeteners in German waste water and surface water and in soil aquifer treatment (SAT).
Analytical and bioanalytical chemistry

Expert panel report on a study of Splenda in male rats.
Regulatory toxicology and pharmacology : RTP

Sweet taste receptor expressed in pancreatic beta-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion.
PloS one

Susceptibility to gut leakiness: a possible mechanism for endotoxaemia in non-alcoholic steatohepatitis.
Liver international : official journal of the International Association for the Study of the Liver

Simultaneous determination of nonnutritive sweeteners in foods by HPLC/ESI-MS.
Journal of agricultural and food chemistry

Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo.
American journal of physiology. Endocrinology and metabolism

Kinetic spectrophotometric methods for the determination of artificial sweetener (sucralose) in tablets.
Drug testing and analysis

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