Scientific studies on guggul

Last updated: September 25, 2013
Resin from the mukul myrrh tree, guggul, can it be used for treating hypercholesterolemia? A randomized, controlled study.
Complementary therapies in medicine

The guggul for chronic diseases: ancient medicine, modern targets.
Anticancer research

1H and 13C assignments of five cembrenes from guggul.
Magnetic resonance in chemistry : MRC

z-Guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, inhibits angiogenesis in vitro and in vivo.
Molecular cancer therapeutics

Guggulsterone inhibits angiogenesis by blocking STAT3 and VEGF expression in colon cancer cells.
Oncology reports

Guggulsterone, a plant sterol, inhibits NF-kappaB activation and protects pancreatic beta cells from cytokine toxicity.
Molecular and cellular endocrinology

Reversal of Multidrug Resistance by Guggulsterone in Drug-Resistant MCF-7 Cell Lines.

Identification of a novel agonist of peroxisome proliferator-activated receptors alpha and gamma that may contribute to the anti-diabetic activity of guggulipid in Lep(ob)/Lep(ob) mice.
The Journal of nutritional biochemistry

Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3.

Guggulsterone inhibits osteoclastogenesis induced by receptor activator of nuclear factor-kappaB ligand and by tumor cells by suppressing nuclear factor-kappaB activation.
Clinical cancer research : an official journal of the American Association for Cancer Research

Effects of plant sterols on human multidrug transporters ABCB1 and ABCC1.
Biochemical and biophysical research communications

Protection against hydrogen peroxide-induced cytotoxicity in PC12 cells by guggulsterone.
Yao xue xue bao = Acta pharmaceutica Sinica

Guggulsterone suppresses the activation of transcription factor IRF3 induced by TLR3 or TLR4 agonists.
International immunopharmacology

Evaluation of guggulipid and nimesulide on production of inflammatory mediators and GFAP expression in LPS stimulated rat astrocytoma, cell line (C6).
Journal of ethnopharmacology

Reversal of P-glycoprotein-mediated multidrug resistance by guggulsterone in doxorubicin-resistant human myelogenous leukemia (K562/DOX) cells.
Die Pharmazie

Guggulsterone, an anti-inflammatory phytosterol, inhibits tissue factor and arterial thrombosis.
Basic research in cardiology

Guggulsterone blocks IL-1beta-mediated inflammatory responses by suppressing NF-kappaB activation in fibroblast-like synoviocytes.
Life sciences

Chemical Characterization of a Commercial Commiphora wightii Resin Sample and Chemical Profiling to Assess for Authenticity.
Planta medica

Guggulsterone induces apoptosis in colon cancer cells and inhibits tumor growth in murine colorectal cancer xenografts.
Cancer letters

Guggullipid derivatives: synthesis and applications.
Chemistry and physics of lipids

Novel guggulsterone derivative GG-52 inhibits NF-kappaB signaling in intestinal epithelial cells and attenuates acute murine colitis.
Laboratory investigation; a journal of technical methods and pathology

Effects of guggulsterone isolated from Commiphora mukul in high fat diet induced diabetic rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Effect of guggulsterone and cembranoids of Commiphora mukul on pancreatic phospholipase A(2): role in hypocholesterolemia.
Journal of natural products

Inhibition of EGFR-STAT3 signaling with erlotinib prevents carcinogenesis in a chemically-induced mouse model of oral squamous cell carcinoma.
Cancer prevention research (Philadelphia, Pa.)

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