|
|
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result sql = Pneumotoxic effects of radioactive dust (RD) from a nuclear power plant in Kozloduy, Bulgaria.
Pneumotoxic effects of radioactive dust (RD) from a nuclear power plant in Kozloduy, Bulgaria.char = <;code = 60
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char = 6;code = 54
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result sql = BACKGROUND : Airborne radioactive particles isolated from the reactor halls of nuclear power plants are a potential risk to the respiratory system of the working staff. Such radioactive dust (RD) from the Nuclear Power Plant, Kozloduy, Bulgaria was investigated.
METHODS : The RD was administered intratracheally to 60 male Wistar rats as an aqueous suspension and the biological effects are estimated, using sensitive biological markers in bronchoalveolar lavage fluid (BALF) and important parameters of the pulmonary antioxidant defense.
RESULTS : The results obtained show that RD increases the total cell number, the activities of the lactate dehydrogenase and alkaline phosphatase as well as the protein content in BALF. The activities of superoxide dismutase and catalase in lung homogenate are decreased while activity of the glutathione peroxidase and the content of non-protein sulfhydrils is elevated.
CONCLUSIONS : It is concluded that the RD causes transitory toxic effect on lung tissue and changes the correlation between the elements of the pulmonary antioxidative defense.
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result sql = Pneumotoxic effects of radioactive dust (RD) from a nuclear power plant in Kozloduy, Bulgaria.
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char = u;code = 117
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char = s;code = 115
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char = ;code = 32
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char = n;code = 110
char = ;code = 32
char = l;code = 108
char = u;code = 117
char = n;code = 110
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char = ;code = 32
char = h;code = 104
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char = m;code = 109
char = o;code = 111
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char = f;code = 102
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = g;code = 103
char = l;code = 108
char = u;code = 117
char = t;code = 116
char = a;code = 97
char = t;code = 116
char = h;code = 104
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = e;code = 101
char = ;code = 32
char = p;code = 112
char = e;code = 101
char = r;code = 114
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char = n;code = 110
char = t;code = 116
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char = f;code = 102
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char = p;code = 112
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char = i;code = 105
char = n;code = 110
char = ;code = 32
char = s;code = 115
char = u;code = 117
char = l;code = 108
char = f;code = 102
char = h;code = 104
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char = l;code = 108
char = s;code = 115
char = ;code = 32
char = i;code = 105
char = s;code = 115
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char = e;code = 101
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char = a;code = 97
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char = i;code = 105
char = s;code = 115
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char = d;code = 100
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char = t;code = 116
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char = s;code = 115
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char = a;code = 97
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char = g;code = 103
char = e;code = 101
char = s;code = 115
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = c;code = 99
char = o;code = 111
char = r;code = 114
char = r;code = 114
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char = l;code = 108
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = b;code = 98
char = e;code = 101
char = t;code = 116
char = w;code = 119
char = e;code = 101
char = e;code = 101
char = n;code = 110
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = e;code = 101
char = l;code = 108
char = e;code = 101
char = m;code = 109
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = s;code = 115
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = p;code = 112
char = u;code = 117
char = l;code = 108
char = m;code = 109
char = o;code = 111
char = n;code = 110
char = a;code = 97
char = r;code = 114
char = y;code = 121
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = x;code = 120
char = i;code = 105
char = d;code = 100
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = v;code = 118
char = e;code = 101
char = ;code = 32
char = d;code = 100
char = e;code = 101
char = f;code = 102
char = e;code = 101
char = n;code = 110
char = s;code = 115
char = e;code = 101
char = .;code = 46
result sql = BACKGROUND : Airborne radioactive particles isolated from the reactor halls of nuclear power plants are a potential risk to the respiratory system of the working staff. Such radioactive dust (RD) from the Nuclear Power Plant, Kozloduy, Bulgaria was investigated.
METHODS : The RD was administered intratracheally to 60 male Wistar rats as an aqueous suspension and the biological effects are estimated, using sensitive biological markers in bronchoalveolar lavage fluid (BALF) and important parameters of the pulmonary antioxidant defense.
RESULTS : The results obtained show that RD increases the total cell number, the activities of the lactate dehydrogenase and alkaline phosphatase as well as the protein content in BALF. The activities of superoxide dismutase and catalase in lung homogenate are decreased while activity of the glutathione peroxidase and the content of non-protein sulfhydrils is elevated.
CONCLUSIONS : It is concluded that the RD causes transitory toxic effect on lung tissue and changes the correlation between the elements of the pulmonary antioxidative defense.
Publication: Am. J. Ind. Med. 2000 Dec ;38(6)::639-43.
Publication Date: 2000 Dec
Study Author(s): Salovsky, P;Shopova, V;Dancheva, V;
Institution: Department of Disaster Medicine, University School of Medicine-Pleven, 1, Kliment Ohridski St., 5800 Pleven, Bulgaria.
Shortcut link to this study:
Publication Date: 2000 Dec
Study Author(s): Salovsky, P;Shopova, V;Dancheva, V;
Institution: Department of Disaster Medicine, University School of Medicine-Pleven, 1, Kliment Ohridski St., 5800 Pleven, Bulgaria.
Shortcut link to this study:
BACKGROUND : Airborne radioactive particles isolated from the reactor halls of nuclear power plants are a potential risk to the respiratory system of the working staff. Such radioactive dust (RD) from the Nuclear Power Plant, Kozloduy, Bulgaria was investigated.
METHODS : The RD was administered intratracheally to 60 male Wistar rats as an aqueous suspension and the biological effects are estimated, using sensitive biological markers in bronchoalveolar lavage fluid (BALF) and important parameters of the pulmonary antioxidant defense.
RESULTS : The results obtained show that RD increases the total cell number, the activities of the lactate dehydrogenase and alkaline phosphatase as well as the protein content in BALF. The activities of superoxide dismutase and catalase in lung homogenate are decreased while activity of the glutathione peroxidase and the content of non-protein sulfhydrils is elevated.
CONCLUSIONS : It is concluded that the RD causes transitory toxic effect on lung tissue and changes the correlation between the elements of the pulmonary antioxidative defense.
METHODS : The RD was administered intratracheally to 60 male Wistar rats as an aqueous suspension and the biological effects are estimated, using sensitive biological markers in bronchoalveolar lavage fluid (BALF) and important parameters of the pulmonary antioxidant defense.
RESULTS : The results obtained show that RD increases the total cell number, the activities of the lactate dehydrogenase and alkaline phosphatase as well as the protein content in BALF. The activities of superoxide dismutase and catalase in lung homogenate are decreased while activity of the glutathione peroxidase and the content of non-protein sulfhydrils is elevated.
CONCLUSIONS : It is concluded that the RD causes transitory toxic effect on lung tissue and changes the correlation between the elements of the pulmonary antioxidative defense.
PMID: 11071686
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