|
|
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result sql = Effect of systemic monosodium glutamate (MSG) on headache and pericranial muscle sensitivity.
Effect of systemic monosodium glutamate (MSG) on headache and pericranial muscle sensitivity.char = W;code = 87
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result sql = We conducted a double-blinded, placebo-controlled, crossover study to investigate the occurrence of adverse effects such as headache as well as pain and mechanical sensitivity in pericranial muscles after oral administration of monosodium glutamate (MSG). In three sessions, 14 healthy men drank sugar-free soda that contained either MSG (75 or 150 mg/kg) or NaCl (24 mg/kg, placebo). Plasma glutamate level, pain, pressure pain thresholds and tolerance levels, blood pressure (BP), heart rate and reported adverse effects were assessed for 2 h. No muscle pain or robust changes in mechanical sensitivity were detected, but there was a significant increase in reports of headache and subjectively reported pericranial muscle tenderness after MSG. Systolic BP was elevated in the high MSG session compared with low MSG and placebo. These findings add new information to the concept of MSG headache and craniofacial pain sensitivity.
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char = o;code = 111
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result sql = Effect of systemic monosodium glutamate (MSG) on headache and pericranial muscle sensitivity.
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char = o;code = 111
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char = ;code = 32
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char = n;code = 110
char = c;code = 99
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char = p;code = 112
char = t;code = 116
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = M;code = 77
char = S;code = 83
char = G;code = 71
char = ;code = 32
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char = o;code = 111
char = f;code = 102
char = a;code = 97
char = c;code = 99
char = i;code = 105
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = p;code = 112
char = a;code = 97
char = i;code = 105
char = n;code = 110
char = ;code = 32
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char = e;code = 101
char = n;code = 110
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char = i;code = 105
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result sql = We conducted a double-blinded, placebo-controlled, crossover study to investigate the occurrence of adverse effects such as headache as well as pain and mechanical sensitivity in pericranial muscles after oral administration of monosodium glutamate (MSG). In three sessions, 14 healthy men drank sugar-free soda that contained either MSG (75 or 150 mg/kg) or NaCl (24 mg/kg, placebo). Plasma glutamate level, pain, pressure pain thresholds and tolerance levels, blood pressure (BP), heart rate and reported adverse effects were assessed for 2 h. No muscle pain or robust changes in mechanical sensitivity were detected, but there was a significant increase in reports of headache and subjectively reported pericranial muscle tenderness after MSG. Systolic BP was elevated in the high MSG session compared with low MSG and placebo. These findings add new information to the concept of MSG headache and craniofacial pain sensitivity.
Publication: Cephalalgia 2010 Jan ;30(1)::68-76. :doi: 10.1111/j.1468-2982.2009.01881.x.
Publication Date: 2010 Jan
Study Author(s): Baad-Hansen, L;Cairns, Be;Ernberg, M;Svensson, P;
Institution: Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Aarhus, Denmark. [email protected]
Shortcut link to this study:
Publication Date: 2010 Jan
Study Author(s): Baad-Hansen, L;Cairns, Be;Ernberg, M;Svensson, P;
Institution: Department of Clinical Oral Physiology, School of Dentistry, University of Aarhus, Aarhus, Denmark. [email protected]
Shortcut link to this study:
We conducted a double-blinded, placebo-controlled, crossover study to investigate the occurrence of adverse effects such as headache as well as pain and mechanical sensitivity in pericranial muscles after oral administration of monosodium glutamate (MSG). In three sessions, 14 healthy men drank sugar-free soda that contained either MSG (75 or 150 mg/kg) or NaCl (24 mg/kg, placebo). Plasma glutamate level, pain, pressure pain thresholds and tolerance levels, blood pressure (BP), heart rate and reported adverse effects were assessed for 2 h. No muscle pain or robust changes in mechanical sensitivity were detected, but there was a significant increase in reports of headache and subjectively reported pericranial muscle tenderness after MSG. Systolic BP was elevated in the high MSG session compared with low MSG and placebo. These findings add new information to the concept of MSG headache and craniofacial pain sensitivity.
PMID: 19438927
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