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result sql = Effect of Chlorella vulgaris on lipid metabolism in Wistar rats fed high fat diet.
Effect of Chlorella vulgaris on lipid metabolism in Wistar rats fed high fat diet.
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char = h;code = 104
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char = ;code = 32
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char = ;code = 32
char = g;code = 103
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char = p;code = 112
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char = h;code = 104
char = a;code = 97
char = n;code = 110
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char = %;code = 37
char = ;code = 32
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char = i;code = 105
char = n;code = 110
char = ;code = 32
char = n;code = 110
char = o;code = 111
char = r;code = 114
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char = a;code = 97
char = l;code = 108
char = ;code = 32
char = d;code = 100
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char = e;code = 101
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char = ;code = 32
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char = d;code = 100
char = ;code = 32
char = h;code = 104
char = i;code = 105
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char = h;code = 104
char = ;code = 32
char = f;code = 102
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char = ;code = 32
char = d;code = 100
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char = g;code = 103
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char = u;code = 117
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char = c;code = 99
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char = .;code = 46
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char = T;code = 84
char = h;code = 104
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char = e;code = 101
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char = t;code = 116
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char = h;code = 104
char = l;code = 108
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char = l;code = 108
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char = a;code = 97
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char = r;code = 114
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char = e;code = 101
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char = i;code = 105
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char = ;code = 32
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result sql = This study was performed to investigate effects of Chlorella vulgaris on lipid metabolism in rats fed high fat diet. Sixty 6-week-old male Wistar rats were divided into two groups; normal diet group and high fat diet group, then the rats in each group were further divided into three subgroups and fed 0%, 5% and 10% (w/w) chlorella-containing diets, respectively, and raised for 9 weeks. Serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activity and total protein and albumin concentration were not different among groups. Serum total lipids and liver TG concentration were significantly lower in 5% and 10% chlorella groups than 0% chlorella group in high fat diet groups (p<0.05). Serum TG, serum total cholesterol, liver total lipid and liver total cholesterol concentrations were significantly lower in 10% chlorella groups than 0% chlorella group in high fat diet groups (p<0.05). Fecal total lipid, TG and total cholesterol excretions were significantly higher in 5% and 10% chlorella groups than 0% chlorella groups in normal diet and high fat diet groups, respectively (p<0.05). These results suggest that Chlorella vulgaris is effective for prevention of dyslipidemia which may be due to the modulation of lipid metabolism and increased fecal excretion of lipid.

Publication: Nutr Res Pract 2008 Winter ;2(4)::204-10. :doi: 10.4162/nrp.2008.2.4.204.
Publication Date: 2008 Winter
Study Author(s): Lee, Hee Sun;Park, Hoon Jung;Kim, Mi Kyung;
Institution: Department of Nutritional Science and Food Management, Ewha Womans University, 11-1 Daehyeon-dong, Seodaemun-gu, Seoul 120-750, Korea.
Shortcut link to this study:
This study was performed to investigate effects of Chlorella vulgaris on lipid metabolism in rats fed high fat diet. Sixty 6-week-old male Wistar rats were divided into two groups; normal diet group and high fat diet group, then the rats in each group were further divided into three subgroups and fed 0%, 5% and 10% (w/w) chlorella-containing diets, respectively, and raised for 9 weeks. Serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activity and total protein and albumin concentration were not different among groups. Serum total lipids and liver TG concentration were significantly lower in 5% and 10% chlorella groups than 0% chlorella group in high fat diet groups (p<0.05). Serum TG, serum total cholesterol, liver total lipid and liver total cholesterol concentrations were significantly lower in 10% chlorella groups than 0% chlorella group in high fat diet groups (p<0.05). Fecal total lipid, TG and total cholesterol excretions were significantly higher in 5% and 10% chlorella groups than 0% chlorella groups in normal diet and high fat diet groups, respectively (p<0.05). These results suggest that Chlorella vulgaris is effective for prevention of dyslipidemia which may be due to the modulation of lipid metabolism and increased fecal excretion of lipid.
PMID: 20016720

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