|
|
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char = .;code = 46
result sql = Topical treatment with coenzyme Q10-containing formulas improves skin's Q10 level and provides antioxidative effects.
Topical treatment with coenzyme Q10-containing formulas improves skin's Q10 level and provides antioxidative effects.char = U;code = 85
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char = k;code = 107
char = e;code = 101
char = r;code = 114
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char = i;code = 105
char = n;code = 110
char = o;code = 111
char = c;code = 99
char = y;code = 121
char = t;code = 116
char = e;code = 101
char = s;code = 115
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char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
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char = c;code = 99
char = o;code = 111
char = n;code = 110
char = c;code = 99
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char = r;code = 114
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = s;code = 115
char = ;code = 32
char = e;code = 101
char = q;code = 113
char = u;code = 117
char = i;code = 105
char = v;code = 118
char = a;code = 97
char = l;code = 108
char = e;code = 101
char = n;code = 110
char = t;code = 116
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char = t;code = 116
char = o;code = 111
char = ;code = 32
char = t;code = 116
char = r;code = 114
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char = e;code = 101
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char = s;code = 115
char = k;code = 107
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = s;code = 115
char = h;code = 104
char = o;code = 111
char = w;code = 119
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = a;code = 97
char = ;code = 32
char = s;code = 115
char = i;code = 105
char = g;code = 103
char = n;code = 110
char = i;code = 105
char = f;code = 102
char = i;code = 105
char = c;code = 99
char = a;code = 97
char = n;code = 110
char = t;code = 116
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char = a;code = 97
char = u;code = 117
char = g;code = 103
char = m;code = 109
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
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char = o;code = 111
char = f;code = 102
char = ;code = 32
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char = e;code = 101
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char = ;code = 32
char = M;code = 77
char = o;code = 111
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char = e;code = 101
char = o;code = 111
char = v;code = 118
char = e;code = 101
char = r;code = 114
char = ,;code = 44
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = s;code = 115
char = u;code = 117
char = l;code = 108
char = t;code = 116
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char = m;code = 109
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char = s;code = 115
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char = r;code = 114
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char = t;code = 116
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char = t;code = 116
char = h;code = 104
char = a;code = 97
char = t;code = 116
char = ;code = 32
char = s;code = 115
char = t;code = 116
char = r;code = 114
char = e;code = 101
char = s;code = 115
char = s;code = 115
char = e;code = 101
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char = s;code = 115
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char = i;code = 105
char = n;code = 110
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char = b;code = 98
char = e;code = 101
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char = e;code = 101
char = f;code = 102
char = i;code = 105
char = t;code = 116
char = s;code = 115
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char = f;code = 102
char = r;code = 114
char = o;code = 111
char = m;code = 109
char = ;code = 32
char = t;code = 116
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char = t;code = 116
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char = a;code = 97
char = t;code = 116
char = m;code = 109
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = ;code = 32
char = b;code = 98
char = y;code = 121
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = d;code = 100
char = u;code = 117
char = c;code = 99
char = t;code = 116
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char = i;code = 105
char = n;code = 110
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char = r;code = 114
char = e;code = 101
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char = s;code = 115
char = e;code = 101
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = t;code = 116
char = i;code = 105
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char = d;code = 100
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char = n;code = 110
char = t;code = 116
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char = c;code = 99
char = a;code = 97
char = p;code = 112
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char = ©;code = 169
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char = o;code = 111
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char = ;code = 32
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char = 1;code = 49
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char = 3;code = 51
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result sql = Ubiquinone (coenzyme Q10, Q10) represents an endogenously synthesized lipid-soluble antioxidant which is crucial for cellular energy production but is diminished with age and under the influence of external stress factors in human skin. Here, it is shown that topical Q10 treatment is beneficial with regard to effective Q10 replenishment, augmentation of cellular energy metabolism, and antioxidant effects. Application of Q10-containing formulas significantly increased the levels of this quinone on the skin surface. In the deeper layers of the epidermis the ubiquinone level was significantly augmented indicating effective supplementation. Concurrent elevation of ubiquinol levels suggested metabolic transformation of ubiquinone resulting from increased energy metabolism. Incubation of cultured human keratinocytes with Q10 concentrations equivalent to treated skin showed a significant augmentation of energy metabolism. Moreover, the results demonstrated that stressed skin benefits from the topical Q10 treatment by reduction of free radicals and an increase in antioxidant capacity. © 2015 BioFactors, 41(6):383-390, 2015.
char = o;code = 111
char = p;code = 112
char = i;code = 105
char = c;code = 99
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = t;code = 116
char = r;code = 114
char = e;code = 101
char = a;code = 97
char = t;code = 116
char = m;code = 109
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = c;code = 99
char = o;code = 111
char = e;code = 101
char = n;code = 110
char = z;code = 122
char = y;code = 121
char = m;code = 109
char = e;code = 101
char = ;code = 32
char = Q;code = 81
char = 1;code = 49
char = 0;code = 48
char = -;code = 45
char = c;code = 99
char = o;code = 111
char = n;code = 110
char = t;code = 116
char = a;code = 97
char = i;code = 105
char = n;code = 110
char = i;code = 105
char = n;code = 110
char = g;code = 103
char = ;code = 32
char = f;code = 102
char = o;code = 111
char = r;code = 114
char = m;code = 109
char = u;code = 117
char = l;code = 108
char = a;code = 97
char = s;code = 115
char = ;code = 32
char = i;code = 105
char = m;code = 109
char = p;code = 112
char = r;code = 114
char = o;code = 111
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char = e;code = 101
char = s;code = 115
char = ;code = 32
char = s;code = 115
char = k;code = 107
char = i;code = 105
char = n;code = 110
char = ';code = 39
char = s;code = 115
char = ;code = 32
char = Q;code = 81
char = 1;code = 49
char = 0;code = 48
char = ;code = 32
char = l;code = 108
char = e;code = 101
char = v;code = 118
char = e;code = 101
char = l;code = 108
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = p;code = 112
char = r;code = 114
char = o;code = 111
char = v;code = 118
char = i;code = 105
char = d;code = 100
char = e;code = 101
char = s;code = 115
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = x;code = 120
char = i;code = 105
char = d;code = 100
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = v;code = 118
char = e;code = 101
char = ;code = 32
char = e;code = 101
char = f;code = 102
char = f;code = 102
char = e;code = 101
char = c;code = 99
char = t;code = 116
char = s;code = 115
char = .;code = 46
result sql = Topical treatment with coenzyme Q10-containing formulas improves skin's Q10 level and provides antioxidative effects.
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char = q;code = 113
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char = m;code = 109
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char = l;code = 108
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char = d;code = 100
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char = r;code = 114
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = n;code = 110
char = o;code = 111
char = c;code = 99
char = y;code = 121
char = t;code = 116
char = e;code = 101
char = s;code = 115
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = Q;code = 81
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char = 0;code = 48
char = ;code = 32
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char = c;code = 99
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char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
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char = ;code = 32
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char = u;code = 117
char = i;code = 105
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char = a;code = 97
char = l;code = 108
char = e;code = 101
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char = t;code = 116
char = o;code = 111
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char = t;code = 116
char = r;code = 114
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char = a;code = 97
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char = e;code = 101
char = d;code = 100
char = ;code = 32
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char = k;code = 107
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = s;code = 115
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char = o;code = 111
char = w;code = 119
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = a;code = 97
char = ;code = 32
char = s;code = 115
char = i;code = 105
char = g;code = 103
char = n;code = 110
char = i;code = 105
char = f;code = 102
char = i;code = 105
char = c;code = 99
char = a;code = 97
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char = t;code = 116
char = ;code = 32
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char = g;code = 103
char = m;code = 109
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char = n;code = 110
char = t;code = 116
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = e;code = 101
char = n;code = 110
char = e;code = 101
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char = g;code = 103
char = y;code = 121
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char = m;code = 109
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char = t;code = 116
char = a;code = 97
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char = l;code = 108
char = i;code = 105
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char = m;code = 109
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char = ;code = 32
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char = r;code = 114
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char = ;code = 32
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char = u;code = 117
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char = t;code = 116
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char = e;code = 101
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char = n;code = 110
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char = n;code = 110
char = c;code = 99
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char = e;code = 101
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char = e;code = 101
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char = n;code = 110
char = ;code = 32
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char = n;code = 110
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char = i;code = 105
char = o;code = 111
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char = i;code = 105
char = d;code = 100
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char = t;code = 116
char = ;code = 32
char = c;code = 99
char = a;code = 97
char = p;code = 112
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char = c;code = 99
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char = t;code = 116
char = y;code = 121
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char = ;code = 32
char = ©;code = 169
char = ;code = 32
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char = 1;code = 49
char = 5;code = 53
char = ;code = 32
char = B;code = 66
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char = o;code = 111
char = F;code = 70
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char = ;code = 32
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char = (;code = 40
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char = :;code = 58
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char = 8;code = 56
char = 3;code = 51
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char = 3;code = 51
char = 9;code = 57
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result sql = Ubiquinone (coenzyme Q10, Q10) represents an endogenously synthesized lipid-soluble antioxidant which is crucial for cellular energy production but is diminished with age and under the influence of external stress factors in human skin. Here, it is shown that topical Q10 treatment is beneficial with regard to effective Q10 replenishment, augmentation of cellular energy metabolism, and antioxidant effects. Application of Q10-containing formulas significantly increased the levels of this quinone on the skin surface. In the deeper layers of the epidermis the ubiquinone level was significantly augmented indicating effective supplementation. Concurrent elevation of ubiquinol levels suggested metabolic transformation of ubiquinone resulting from increased energy metabolism. Incubation of cultured human keratinocytes with Q10 concentrations equivalent to treated skin showed a significant augmentation of energy metabolism. Moreover, the results demonstrated that stressed skin benefits from the topical Q10 treatment by reduction of free radicals and an increase in antioxidant capacity. © 2015 BioFactors, 41(6):383-390, 2015.
Publication: Biofactors 2015 Nov;41(6):383-90.
Publication Date: Nov 2015
Study Author(s): Knott Anja A ; Achterberg Volker V ; Smuda Christoph C ; Mielke Heiko H ; Sperling Gabi G ; Dunckelmann Katja K ; Vogelsang Alexandra A ; Krüger Andrea A ; Schwengler Helge H ; Behtash Mojgan M ; Kristof Sonja S ; Diekmann Heike H ; Eisenberg Tanya T ; Berroth Andreas A ; Hildebrand Janosch J ; Siegner Ralf R ; Winnefeld Marc M ; Teuber Frank F ; Fey Sven S ; Möbius Janne J ; Retzer Dana D ; Burkhardt Thorsten T ; Lüttke Juliane J ; Blatt Thomas T ;
Institution: Beiersdorf AG, Research & Development, Hamburg, Germany.
Shortcut link to this study:
Publication Date: Nov 2015
Study Author(s): Knott Anja A ; Achterberg Volker V ; Smuda Christoph C ; Mielke Heiko H ; Sperling Gabi G ; Dunckelmann Katja K ; Vogelsang Alexandra A ; Krüger Andrea A ; Schwengler Helge H ; Behtash Mojgan M ; Kristof Sonja S ; Diekmann Heike H ; Eisenberg Tanya T ; Berroth Andreas A ; Hildebrand Janosch J ; Siegner Ralf R ; Winnefeld Marc M ; Teuber Frank F ; Fey Sven S ; Möbius Janne J ; Retzer Dana D ; Burkhardt Thorsten T ; Lüttke Juliane J ; Blatt Thomas T ;
Institution: Beiersdorf AG, Research & Development, Hamburg, Germany.
Shortcut link to this study:
Ubiquinone (coenzyme Q10, Q10) represents an endogenously synthesized lipid-soluble antioxidant which is crucial for cellular energy production but is diminished with age and under the influence of external stress factors in human skin. Here, it is shown that topical Q10 treatment is beneficial with regard to effective Q10 replenishment, augmentation of cellular energy metabolism, and antioxidant effects. Application of Q10-containing formulas significantly increased the levels of this quinone on the skin surface. In the deeper layers of the epidermis the ubiquinone level was significantly augmented indicating effective supplementation. Concurrent elevation of ubiquinol levels suggested metabolic transformation of ubiquinone resulting from increased energy metabolism. Incubation of cultured human keratinocytes with Q10 concentrations equivalent to treated skin showed a significant augmentation of energy metabolism. Moreover, the results demonstrated that stressed skin benefits from the topical Q10 treatment by reduction of free radicals and an increase in antioxidant capacity. © 2015 BioFactors, 41(6):383-390, 2015.
PMID: 26648450
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