|
|
char = E;code = 69
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char = m;code = 109
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char = N;code = 78
char = A;code = 65
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char = .;code = 46
result sql = Estrogen receptor beta mRNA in colon cancer cells: growth effects of estrogen and genistein.
Estrogen receptor beta mRNA in colon cancer cells: growth effects of estrogen and genistein.char = K;code = 75
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char = o;code = 111
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char = e;code = 101
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char = d;code = 100
char = e;code = 101
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char = o;code = 111
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char = s;code = 115
char = t;code = 116
char = r;code = 114
char = a;code = 97
char = t;code = 116
char = e;code = 101
char = d;code = 100
char = ;code = 32
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char = h;code = 104
char = a;code = 97
char = t;code = 116
char = ;code = 32
char = f;code = 102
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char = v;code = 118
char = e;code = 101
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char = h;code = 104
char = u;code = 117
char = m;code = 109
char = a;code = 97
char = n;code = 110
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char = c;code = 99
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char = c;code = 99
char = a;code = 97
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char = l;code = 108
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char = ;code = 32
char = H;code = 72
char = T;code = 84
char = 2;code = 50
char = 9;code = 57
char = ,;code = 44
char = ;code = 32
char = C;code = 67
char = o;code = 111
char = l;code = 108
char = o;code = 111
char = 3;code = 51
char = 2;code = 50
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char = L;code = 76
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char = S;code = 83
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char = 4;code = 52
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char = H;code = 72
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char = 1;code = 49
char = 1;code = 49
char = 6;code = 54
char = ,;code = 44
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char = e;code = 101
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char = e;code = 101
char = d;code = 100
char = ;code = 32
char = E;code = 69
char = R;code = 82
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char = a;code = 97
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char = m;code = 109
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char = k;code = 107
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char = E;code = 69
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char = a;code = 97
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char = m;code = 109
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char = .;code = 46
char = ;code = 32
char = R;code = 82
char = e;code = 101
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char = f;code = 102
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char = a;code = 97
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char = s;code = 115
char = a;code = 97
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char = d;code = 100
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char = r;code = 114
char = a;code = 97
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char = e;code = 101
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char = ;code = 32
char = t;code = 116
char = h;code = 104
char = a;code = 97
char = t;code = 116
char = ;code = 32
char = t;code = 116
char = h;code = 104
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char = e;code = 101
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char = c;code = 99
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char = c;code = 99
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char = e;code = 101
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char = d;code = 100
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char = b;code = 98
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char = e;code = 101
char = s;code = 115
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char = r;code = 114
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char = g;code = 103
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char = ,;code = 44
char = ;code = 32
char = w;code = 119
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char = i;code = 105
char = l;code = 108
char = e;code = 101
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char = g;code = 103
char = e;code = 101
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char = i;code = 105
char = s;code = 115
char = t;code = 116
char = e;code = 101
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = p;code = 112
char = o;code = 111
char = s;code = 115
char = s;code = 115
char = e;code = 101
char = s;code = 115
char = s;code = 115
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = s;code = 115
char = l;code = 108
char = i;code = 105
char = g;code = 103
char = h;code = 104
char = t;code = 116
char = ;code = 32
char = g;code = 103
char = r;code = 114
char = o;code = 111
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char = h;code = 104
char = ;code = 32
char = i;code = 105
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char = i;code = 105
char = b;code = 98
char = i;code = 105
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char = f;code = 102
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char = H;code = 72
char = T;code = 84
char = 2;code = 50
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char = ,;code = 44
char = ;code = 32
char = C;code = 67
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char = l;code = 108
char = o;code = 111
char = 3;code = 51
char = 2;code = 50
char = 0;code = 48
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char = L;code = 76
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char = ;code = 32
char = c;code = 99
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char = 7;code = 55
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char = ;code = 32
char = T;code = 84
char = a;code = 97
char = k;code = 107
char = e;code = 101
char = n;code = 110
char = ;code = 32
char = t;code = 116
char = o;code = 111
char = g;code = 103
char = e;code = 101
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = p;code = 112
char = r;code = 114
char = e;code = 101
char = v;code = 118
char = i;code = 105
char = o;code = 111
char = u;code = 117
char = s;code = 115
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char = r;code = 114
char = e;code = 101
char = p;code = 112
char = o;code = 111
char = r;code = 114
char = t;code = 116
char = s;code = 115
char = ,;code = 44
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = s;code = 115
char = e;code = 101
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char = d;code = 100
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char = t;code = 116
char = a;code = 97
char = ;code = 32
char = s;code = 115
char = u;code = 117
char = g;code = 103
char = g;code = 103
char = e;code = 101
char = s;code = 115
char = t;code = 116
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char = t;code = 116
char = h;code = 104
char = a;code = 97
char = t;code = 116
char = ;code = 32
char = E;code = 69
char = R;code = 82
char = a;code = 97
char = l;code = 108
char = p;code = 112
char = h;code = 104
char = a;code = 97
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = E;code = 69
char = R;code = 82
char = b;code = 98
char = e;code = 101
char = t;code = 116
char = a;code = 97
char = ;code = 32
char = m;code = 109
char = a;code = 97
char = y;code = 121
char = ;code = 32
char = h;code = 104
char = a;code = 97
char = v;code = 118
char = e;code = 101
char = ;code = 32
char = d;code = 100
char = i;code = 105
char = f;code = 102
char = f;code = 102
char = e;code = 101
char = r;code = 114
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = ;code = 32
char = b;code = 98
char = i;code = 105
char = o;code = 111
char = l;code = 108
char = o;code = 111
char = g;code = 103
char = i;code = 105
char = c;code = 99
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = f;code = 102
char = u;code = 117
char = n;code = 110
char = c;code = 99
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = s;code = 115
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = c;code = 99
char = o;code = 111
char = l;code = 108
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = c;code = 99
char = e;code = 101
char = l;code = 108
char = l;code = 108
char = s;code = 115
char = .;code = 46
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
result sql = Knowledge regarding the expression of the recently cloned estrogen receptor beta (ERbeta) in colonic mucosa is limited. In this study, we demonstrated that five human colon cancer cell lines, HT29, Colo320, Lovo, SW480, and HCT116, expressed ERbeta mRNA, but lacked ERalpha mRNA. Results from a cell growth assay demonstrated that these colon cancer cells were not influenced by estrogen, while genistein possessed slight growth inhibitory effects on HT29, Colo320 and Lovo cells at 10 microM, at which concentration is stimulated the growth of ERalpha-positive human breast cancer MCF-7 cells. Tamoxifen inhibited the growth of HT29 and Colo320 cells, dose-dependently, as well as MCF-7 cells. A transfected reporter plasmid containing a vitellogenin estrogen response element could be activated by estradiol in Colo320 cells. Taken together with previous reports, these data suggest that ERalpha and ERbeta may have different biological functions in colon cells.
char = s;code = 115
char = t;code = 116
char = r;code = 114
char = o;code = 111
char = g;code = 103
char = e;code = 101
char = n;code = 110
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = c;code = 99
char = e;code = 101
char = p;code = 112
char = t;code = 116
char = o;code = 111
char = r;code = 114
char = ;code = 32
char = b;code = 98
char = e;code = 101
char = t;code = 116
char = a;code = 97
char = ;code = 32
char = m;code = 109
char = R;code = 82
char = N;code = 78
char = A;code = 65
char = ;code = 32
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = c;code = 99
char = o;code = 111
char = l;code = 108
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = c;code = 99
char = a;code = 97
char = n;code = 110
char = c;code = 99
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = c;code = 99
char = e;code = 101
char = l;code = 108
char = l;code = 108
char = s;code = 115
char = :;code = 58
char = ;code = 32
char = g;code = 103
char = r;code = 114
char = o;code = 111
char = w;code = 119
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = e;code = 101
char = f;code = 102
char = f;code = 102
char = e;code = 101
char = c;code = 99
char = t;code = 116
char = s;code = 115
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = e;code = 101
char = s;code = 115
char = t;code = 116
char = r;code = 114
char = o;code = 111
char = g;code = 103
char = e;code = 101
char = n;code = 110
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = g;code = 103
char = e;code = 101
char = n;code = 110
char = i;code = 105
char = s;code = 115
char = t;code = 116
char = e;code = 101
char = i;code = 105
char = n;code = 110
char = .;code = 46
result sql = Estrogen receptor beta mRNA in colon cancer cells: growth effects of estrogen and genistein.
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char = o;code = 111
char = w;code = 119
char = l;code = 108
char = e;code = 101
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char = g;code = 103
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char = g;code = 103
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char = e;code = 101
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char = r;code = 114
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char = s;code = 115
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char = h;code = 104
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char = ,;code = 44
char = ;code = 32
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char = k;code = 107
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char = m;code = 109
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char = s;code = 115
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char = a;code = 97
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char = e;code = 101
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char = ;code = 32
char = c;code = 99
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char = c;code = 99
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char = c;code = 99
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char = t;code = 116
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char = 2;code = 50
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result sql = Knowledge regarding the expression of the recently cloned estrogen receptor beta (ERbeta) in colonic mucosa is limited. In this study, we demonstrated that five human colon cancer cell lines, HT29, Colo320, Lovo, SW480, and HCT116, expressed ERbeta mRNA, but lacked ERalpha mRNA. Results from a cell growth assay demonstrated that these colon cancer cells were not influenced by estrogen, while genistein possessed slight growth inhibitory effects on HT29, Colo320 and Lovo cells at 10 microM, at which concentration is stimulated the growth of ERalpha-positive human breast cancer MCF-7 cells. Tamoxifen inhibited the growth of HT29 and Colo320 cells, dose-dependently, as well as MCF-7 cells. A transfected reporter plasmid containing a vitellogenin estrogen response element could be activated by estradiol in Colo320 cells. Taken together with previous reports, these data suggest that ERalpha and ERbeta may have different biological functions in colon cells.
Publication: Biochem. Biophys. Res. Commun. 2000 Apr 13 ;270(2)::425-31.
Publication Date: 2000 Apr 13
Study Author(s): Arai, N;Ström, A;Rafter, J J;Gustafsson, J A;
Institution: Department of Medical Nutrition, Karolinska Institute, NOVUM, Huddinge, S-141 84, Sweden.
Shortcut link to this study:
Publication Date: 2000 Apr 13
Study Author(s): Arai, N;Ström, A;Rafter, J J;Gustafsson, J A;
Institution: Department of Medical Nutrition, Karolinska Institute, NOVUM, Huddinge, S-141 84, Sweden.
Shortcut link to this study:
Knowledge regarding the expression of the recently cloned estrogen receptor beta (ERbeta) in colonic mucosa is limited. In this study, we demonstrated that five human colon cancer cell lines, HT29, Colo320, Lovo, SW480, and HCT116, expressed ERbeta mRNA, but lacked ERalpha mRNA. Results from a cell growth assay demonstrated that these colon cancer cells were not influenced by estrogen, while genistein possessed slight growth inhibitory effects on HT29, Colo320 and Lovo cells at 10 microM, at which concentration is stimulated the growth of ERalpha-positive human breast cancer MCF-7 cells. Tamoxifen inhibited the growth of HT29 and Colo320 cells, dose-dependently, as well as MCF-7 cells. A transfected reporter plasmid containing a vitellogenin estrogen response element could be activated by estradiol in Colo320 cells. Taken together with previous reports, these data suggest that ERalpha and ERbeta may have different biological functions in colon cells.
PMID: 10753641
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