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result sql = [Effects of quercetin on the expression of VEGF-C and VEGFR-3 in human cancer MGC-803 cells].
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result sql = AIM : To investigate the mechanism of quercetin on the inhibition of the lymphatic metastasis in human gastric cancer cells MGC-803.
METHODS : Cells were divided into the control group and the quercetin (Que)-treated group. Immunohistochemistry and RT-PCR were used to detect the expression of vascular endothelial growth factor C (VEGF-C) and VEGFR-3 of human gastric cancer cells MGC-803 in response to Que.
RESULTS : Que significantly decreased the expression of VEGF-C and VEGFR-3 at 40 mumol/L compared with the control group after 48 h (P<0.01).
CONCLUSION : Que can down-regulate the expression of VEGF-C and VEGFR-3 in human gastric cancer cells MGC-803.
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result sql = [Effects of quercetin on the expression of VEGF-C and VEGFR-3 in human cancer MGC-803 cells].
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result sql = AIM : To investigate the mechanism of quercetin on the inhibition of the lymphatic metastasis in human gastric cancer cells MGC-803.
METHODS : Cells were divided into the control group and the quercetin (Que)-treated group. Immunohistochemistry and RT-PCR were used to detect the expression of vascular endothelial growth factor C (VEGF-C) and VEGFR-3 of human gastric cancer cells MGC-803 in response to Que.
RESULTS : Que significantly decreased the expression of VEGF-C and VEGFR-3 at 40 mumol/L compared with the control group after 48 h (P<0.01).
CONCLUSION : Que can down-regulate the expression of VEGF-C and VEGFR-3 in human gastric cancer cells MGC-803.
Publication: Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2009 Aug ;25(8)::678-80.
Publication Date: 2009 Aug
Study Author(s): Yu, Zhi-jun;He, Li-ya;Chen, Yong;Wu, Mian-yun;Zhao, Xue-hua;Wang, Zhen-yu;
Institution: Institute of Cellular and Molecular Biology, College of Medical Science, Wuhan University of Science and Technology, Wuhan 430065, China.
Shortcut link to this study:
Publication Date: 2009 Aug
Study Author(s): Yu, Zhi-jun;He, Li-ya;Chen, Yong;Wu, Mian-yun;Zhao, Xue-hua;Wang, Zhen-yu;
Institution: Institute of Cellular and Molecular Biology, College of Medical Science, Wuhan University of Science and Technology, Wuhan 430065, China.
Shortcut link to this study:
AIM : To investigate the mechanism of quercetin on the inhibition of the lymphatic metastasis in human gastric cancer cells MGC-803.
METHODS : Cells were divided into the control group and the quercetin (Que)-treated group. Immunohistochemistry and RT-PCR were used to detect the expression of vascular endothelial growth factor C (VEGF-C) and VEGFR-3 of human gastric cancer cells MGC-803 in response to Que.
RESULTS : Que significantly decreased the expression of VEGF-C and VEGFR-3 at 40 mumol/L compared with the control group after 48 h (P<0.01).
CONCLUSION : Que can down-regulate the expression of VEGF-C and VEGFR-3 in human gastric cancer cells MGC-803.
METHODS : Cells were divided into the control group and the quercetin (Que)-treated group. Immunohistochemistry and RT-PCR were used to detect the expression of vascular endothelial growth factor C (VEGF-C) and VEGFR-3 of human gastric cancer cells MGC-803 in response to Que.
RESULTS : Que significantly decreased the expression of VEGF-C and VEGFR-3 at 40 mumol/L compared with the control group after 48 h (P<0.01).
CONCLUSION : Que can down-regulate the expression of VEGF-C and VEGFR-3 in human gastric cancer cells MGC-803.
PMID: 19664387
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