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result sql = Clinical implication of F-18 FDG PET/CT for differentiated thyroid cancer in patients with negative diagnostic iodine-123 scan and elevated thyroglobulin.
Clinical implication of F-18 FDG PET/CT for differentiated thyroid cancer in patients with negative diagnostic iodine-123 scan and elevated thyroglobulin.
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char = L;code = 76
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char = C;code = 67
char = T;code = 84
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char = n;code = 110
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char = <;code = 60
char = b;code = 98
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char = <;code = 60
char = b;code = 98
char = r;code = 114
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char = <;code = 60
char = b;code = 98
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char = C;code = 67
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char = <;code = 60
char = /;code = 47
char = b;code = 98
char = >;code = 62
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char = ;code = 32
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char = ;code = 32
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char = i;code = 105
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char = d;code = 100
char = e;code = 101
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char = e;code = 101
char = c;code = 99
char = t;code = 116
char = i;code = 105
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char = a;code = 97
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char = ;code = 32
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char = ;code = 32
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char = e;code = 101
char = n;code = 110
char = t;code = 116
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char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = e;code = 101
char = l;code = 108
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char = v;code = 118
char = a;code = 97
char = t;code = 116
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char = d;code = 100
char = ;code = 32
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char = e;code = 101
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char = u;code = 117
char = t;code = 116
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char = e;code = 101
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char = i;code = 105
char = v;code = 118
char = e;code = 101
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char = I;code = 73
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char = 1;code = 49
char = 2;code = 50
char = 3;code = 51
char = ;code = 32
char = w;code = 119
char = h;code = 104
char = o;code = 111
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char = e;code = 101
char = ;code = 32
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result sql = UNLABELLED : This study aims to investigate the usefulness of F-18 FDG PET/CT in differentiated thyroid cancer (DTC) with elevated serum thyroglobulin (Tg) but negative iodine-123 (I-123) scan.

METHODS : Twenty patients with histopathologically proven DTC, negative diagnostic I-123 scan, and elevated serum Tg levels were prospectively submitted to F-18 FDG PET/CT evaluation. The histopathologic findings consisted of 19 papillary thyroid cancers, 1 follicular thyroid cancer.

RESULTS : F-18 FDG PET/CT identified lesions in 18 out of 20 patients, giving a sensitivity of 90%. Thirteen of the 18 patients revealed limited loco-regional disease. Remaining 5 patients showed distant metastases, consisting of 4 patients with lung metastases and 1 patient with bone metastasis. Two patients revealed negative F-18 FDG PET/CT findings.

CONCLUSION : F-18 FDG PET/CT is suitable for the detection and precise localization of loco-regional recurrences and distant metastases of DTC in patients with elevated serum Tg but negative I-123 whole body scan.

Publication: Eur J Radiol 2009 Apr ;70(1)::17-24. :doi: 10.1016/j.ejrad.2007.12.004.
Publication Date: 2009 Apr
Study Author(s): Kim, Seong-Jang;Lee, Tae Hong;Kim, In-Ju;Kim, Yong-Ki;
Institution: Department of Nuclear Medicine, Pusan National University Hospital, Busan, Republic of Korea. [email protected]
Shortcut link to this study:
UNLABELLED : This study aims to investigate the usefulness of F-18 FDG PET/CT in differentiated thyroid cancer (DTC) with elevated serum thyroglobulin (Tg) but negative iodine-123 (I-123) scan.

METHODS : Twenty patients with histopathologically proven DTC, negative diagnostic I-123 scan, and elevated serum Tg levels were prospectively submitted to F-18 FDG PET/CT evaluation. The histopathologic findings consisted of 19 papillary thyroid cancers, 1 follicular thyroid cancer.

RESULTS : F-18 FDG PET/CT identified lesions in 18 out of 20 patients, giving a sensitivity of 90%. Thirteen of the 18 patients revealed limited loco-regional disease. Remaining 5 patients showed distant metastases, consisting of 4 patients with lung metastases and 1 patient with bone metastasis. Two patients revealed negative F-18 FDG PET/CT findings.

CONCLUSION : F-18 FDG PET/CT is suitable for the detection and precise localization of loco-regional recurrences and distant metastases of DTC in patients with elevated serum Tg but negative I-123 whole body scan.
PMID: 18207685

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