char = A;code = 65
A major decomposition product, citrinin H2, from citrinin on heating with moisture.char = C;code = 67 HPLC : analysis of citrinin after heating under various conditions indicates that citrinin H2 is mainly yielded from citrinin.
Publication: Biosci. Biotechnol. Biochem. 2002 Jan ;66(1)::206-10.
Publication Date: 2002 Jan
Study Author(s): Hirota, Mitsuru;Mehta, Alka;Yoneyama, Keiko;Kitabatake, Naofumi;Menta Alka, B;
Institution: Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University, Kami-ina, Nagano, Japan.
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Citrinin is one of the mycotoxins produced by Penicillium citrinum. We examined the decomposition products after heating citrinin in water at 140 degrees C and isolated a major product, citrinin H2 (3-(3,5-dihydroxy-2-methylphenyl)-2-formyloxy-butane). Citrinin H2 did not show significant cytotoxicity to HeLa cells up to a concentration of 200 microg/ml (% cytotoxicity: 39%) in 63 h of incubation, but citrinin showed severe toxicity at a concentration of 25 microg/ml (% cytotoxicity: 73%) HPLC : analysis of citrinin after heating under various conditions indicates that citrinin H2 is mainly yielded from citrinin.
How is this determined?
