char = K;code = 75
Kinetic isotope effect evidence for a concerted hydrogen transfer mechanism in transfer hydrogenations catalyzed by [p-(Me2CH)C6H4Me]Ru- (NHCHPhCHPhNSO2C6H4-p-CH3).char = T;code = 84
Publication: J. Org. Chem. 2003 Mar 7 ;68(5)::1998-2001.
Publication Date: 2003 Mar 7
Study Author(s): Casey, Charles P;Johnson, Jeffrey B;
Institution: Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
[email protected]
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The isotope effects in the reaction of [p-(Me2CH)C6H4Me]Ru(NHCHPhCHPhNSO2C6H4-p-CH3) (1) with isopropyl alcohol were 1.79 for transfer of hydrogen from OH to N and 2.86 for transfer from CH to Ru. The isotope effect for transfer of deuterium from doubly labeled material (kCHOH/kCDOD = 4.88) was within experimental error of the product of the two individual isotope effects. These isotope effects provide convincing evidence for a mechanism involving concurrent transfer of hydrogen from oxygen to nitrogen and from carbon to ruthenium.
How is this determined?
