char = C;code = 67 char = e;code = 101 char = r;code = 114 char = e;code = 101 char = b;code = 98 char = r;code = 114 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = v;code = 118 char = a;code = 97 char = s;code = 115 char = o;code = 111 char = r;code = 114 char = e;code = 101 char = a;code = 97 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = i;code = 105 char = t;code = 116 char = y;code = 121 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = A;code = 65 char = n;code = 110 char = d;code = 100 char = e;code = 101 char = a;code = 97 char = n;code = 110 char = s;code = 115 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = h;code = 104 char = e;code = 101 char = a;code = 97 char = d;code = 100 char = a;code = 97 char = c;code = 99 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = a;code = 97 char = t;code = 116 char = ;code = 32 char = s;code = 115 char = e;code = 101 char = a;code = 97 char = ;code = 32 char = l;code = 108 char = e;code = 101 char = v;code = 118 char = e;code = 101 char = l;code = 108 char = .;code = 46 result sql = Cerebral vasoreactivity in Andeans and headache at sea level.
Cerebral vasoreactivity in Andeans and headache at sea level.char = H;code = 72 char = e;code = 101 char = a;code = 97 char = d;code = 100 char = a;code = 97 char = c;code = 99 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = i;code = 105 char = s;code = 115 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = m;code = 109 char = m;code = 109 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = C;code = 67 char = e;code = 101 char = r;code = 114 char = r;code = 114 char = o;code = 111 char = ;code = 32 char = d;code = 100 char = e;code = 101 char = ;code = 32 char = P;code = 80 char = a;code = 97 char = s;code = 115 char = c;code = 99 char = o;code = 111 char = ;code = 32 char = (;code = 40 char = C;code = 67 char = P;code = 80 char = );code = 41 char = ,;code = 44 char = ;code = 32 char = P;code = 80 char = e;code = 101 char = r;code = 114 char = u;code = 117 char = ;code = 32 char = (;code = 40 char = a;code = 97 char = l;code = 108 char = t;code = 116 char = i;code = 105 char = t;code = 116 char = u;code = 117 char = d;code = 100 char = e;code = 101 char = ;code = 32 char = 4;code = 52 char = 3;code = 51 char = 3;code = 51 char = 8;code = 56 char = ;code = 32 char = m;code = 109 char = );code = 41 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = w;code = 119 char = a;code = 97 char = s;code = 115 char = ;code = 32 char = p;code = 112 char = r;code = 114 char = e;code = 101 char = s;code = 115 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = a;code = 97 char = l;code = 108 char = l;code = 108 char = ;code = 32 char = p;code = 112 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = s;code = 115 char = ;code = 32 char = w;code = 119 char = i;code = 105 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = c;code = 99 char = h;code = 104 char = r;code = 114 char = o;code = 111 char = n;code = 110 char = i;code = 105 char = c;code = 99 char = ;code = 32 char = m;code = 109 char = o;code = 111 char = u;code = 117 char = n;code = 110 char = t;code = 116 char = a;code = 97 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = s;code = 115 char = i;code = 105 char = c;code = 99 char = k;code = 107 char = n;code = 110 char = e;code = 101 char = s;code = 115 char = s;code = 115 char = ;code = 32 char = (;code = 40 char = C;code = 67 char = M;code = 77 char = S;code = 83 char = );code = 41 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = C;code = 67 char = P;code = 80 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = p;code = 112 char = o;code = 111 char = r;code = 114 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = h;code = 104 char = e;code = 101 char = r;code = 114 char = e;code = 101 char = .;code = 46 char = ;code = 32 char = F;code = 70 char = o;code = 111 char = r;code = 114 char = t;code = 116 char = y;code = 121 char = -;code = 45 char = s;code = 115 char = e;code = 101 char = v;code = 118 char = e;code = 101 char = n;code = 110 char = ;code = 32 char = p;code = 112 char = e;code = 101 char = r;code = 114 char = c;code = 99 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = h;code = 104 char = a;code = 97 char = b;code = 98 char = i;code = 105 char = t;code = 116 char = a;code = 97 char = n;code = 110 char = t;code = 116 char = s;code = 115 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = p;code = 112 char = o;code = 111 char = r;code = 114 char = t;code = 116 char = ;code = 32 char = h;code = 104 char = e;code = 101 char = a;code = 97 char = d;code = 100 char = a;code = 97 char = c;code = 99 char = h;code = 104 char = e;code = 101 char = .;code = 46 char = ;code = 32 char = T;code = 84 char = w;code = 119 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = y;code = 121 char = -;code = 45 char = f;code = 102 char = o;code = 111 char = u;code = 117 char = r;code = 114 char = ;code = 32 char = p;code = 112 char = e;code = 101 char = r;code = 114 char = c;code = 99 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = m;code = 109 char = e;code = 101 char = n;code = 110 char = ;code = 32 char = h;code = 104 char = a;code = 97 char = v;code = 118 char = e;code = 101 char = ;code = 32 char = m;code = 109 char = i;code = 105 char = g;code = 103 char = r;code = 114 char = a;code = 97 char = i;code = 105 char = n;code = 110 char = e;code = 101 char = ;code = 32 char = w;code = 119 char = i;code = 105 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = a;code = 97 char = u;code = 117 char = r;code = 114 char = a;code = 97 char = ,;code = 44 char = ;code = 32 char = w;code = 119 char = i;code = 105 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = ;code = 32 char = a;code = 97 char = v;code = 118 char = e;code = 101 char = r;code = 114 char = a;code = 97 char = g;code = 103 char = e;code = 101 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = 6;code = 54 char = 5;code = 53 char = ;code = 32 char = a;code = 97 char = t;code = 116 char = t;code = 116 char = a;code = 97 char = c;code = 99 char = k;code = 107 char = s;code = 115 char = ;code = 32 char = a;code = 97 char = ;code = 32 char = y;code = 121 char = e;code = 101 char = a;code = 97 char = r;code = 114 char = .;code = 46 char = ;code = 32 char = W;code = 87 char = e;code = 101 char = ;code = 32 char = a;code = 97 char = s;code = 115 char = s;code = 115 char = e;code = 101 char = s;code = 115 char = s;code = 115 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = v;code = 118 char = a;code = 97 char = s;code = 115 char = o;code = 111 char = r;code = 114 char = e;code = 101 char = a;code = 97 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = i;code = 105 char = t;code = 116 char = y;code = 121 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = c;code = 99 char = e;code = 101 char = r;code = 114 char = e;code = 101 char = b;code = 98 char = r;code = 114 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = v;code = 118 char = e;code = 101 char = s;code = 115 char = s;code = 115 char = e;code = 101 char = l;code = 108 char = s;code = 115 char = ;code = 32 char = t;code = 116 char = o;code = 111 char = ;code = 32 char = C;code = 67 char = O;code = 79 char = 2;code = 50 char = ;code = 32 char = b;code = 98 char = y;code = 121 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = b;code = 98 char = r;code = 114 char = e;code = 101 char = a;code = 97 char = t;code = 116 char = h;code = 104 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = t;code = 116 char = o;code = 111 char = ;code = 32 char = N;code = 78 char = O;code = 79 char = ;code = 32 char = b;code = 98 char = y;code = 121 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = a;code = 97 char = d;code = 100 char = m;code = 109 char = i;code = 105 char = n;code = 110 char = i;code = 105 char = s;code = 115 char = t;code = 116 char = r;code = 114 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = i;code = 105 char = s;code = 115 char = o;code = 111 char = s;code = 115 char = o;code = 111 char = r;code = 114 char = b;code = 98 char = i;code = 105 char = t;code = 116 char = e;code = 101 char = ;code = 32 char = d;code = 100 char = i;code = 105 char = n;code = 110 char = i;code = 105 char = t;code = 116 char = r;code = 114 char = a;code = 97 char = t;code = 116 char = e;code = 101 char = ;code = 32 char = (;code = 40 char = I;code = 73 char = D;code = 68 char = N;code = 78 char = );code = 41 char = ,;code = 44 char = ;code = 32 char = a;code = 97 char = ;code = 32 char = n;code = 110 char = i;code = 105 char = t;code = 116 char = r;code = 114 char = i;code = 105 char = c;code = 99 char = ;code = 32 char = o;code = 111 char = x;code = 120 char = i;code = 105 char = d;code = 100 char = e;code = 101 char = ;code = 32 char = (;code = 40 char = N;code = 78 char = O;code = 79 char = );code = 41 char = ;code = 32 char = d;code = 100 char = o;code = 111 char = n;code = 110 char = o;code = 111 char = r;code = 114 char = ,;code = 44 char = ;code = 32 char = u;code = 117 char = s;code = 115 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = ;code = 32 char = t;code = 116 char = r;code = 114 char = a;code = 97 char = n;code = 110 char = s;code = 115 char = c;code = 99 char = r;code = 114 char = a;code = 97 char = n;code = 110 char = i;code = 105 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = D;code = 68 char = o;code = 111 char = p;code = 112 char = p;code = 112 char = l;code = 108 char = e;code = 101 char = r;code = 114 char = ;code = 32 char = u;code = 117 char = l;code = 108 char = t;code = 116 char = r;code = 114 char = a;code = 97 char = s;code = 115 char = o;code = 111 char = u;code = 117 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = m;code = 109 char = i;code = 105 char = d;code = 100 char = d;code = 100 char = l;code = 108 char = e;code = 101 char = ;code = 32 char = c;code = 99 char = e;code = 101 char = r;code = 114 char = e;code = 101 char = b;code = 98 char = r;code = 114 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = a;code = 97 char = r;code = 114 char = t;code = 116 char = e;code = 101 char = r;code = 114 char = y;code = 121 char = ;code = 32 char = (;code = 40 char = M;code = 77 char = C;code = 67 char = A;code = 65 char = );code = 41 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = n;code = 110 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = e;code = 101 char = s;code = 115 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = C;code = 67 char = P;code = 80 char = ,;code = 44 char = ;code = 32 char = s;code = 115 char = o;code = 111 char = m;code = 109 char = e;code = 101 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = w;code = 119 char = h;code = 104 char = o;code = 111 char = m;code = 109 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = f;code = 102 char = f;code = 102 char = e;code = 101 char = r;code = 114 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = f;code = 102 char = r;code = 114 char = o;code = 111 char = m;code = 109 char = ;code = 32 char = C;code = 67 char = M;code = 77 char = S;code = 83 char = .;code = 46 char = ;code = 32 char = W;code = 87 char = e;code = 101 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = p;code = 112 char = e;code = 101 char = a;code = 97 char = t;code = 116 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = m;code = 109 char = e;code = 101 char = a;code = 97 char = s;code = 115 char = u;code = 117 char = r;code = 114 char = e;code = 101 char = m;code = 109 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = s;code = 115 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = L;code = 76 char = i;code = 105 char = m;code = 109 char = a;code = 97 char = ;code = 32 char = (;code = 40 char = a;code = 97 char = l;code = 108 char = t;code = 116 char = i;code = 105 char = t;code = 116 char = u;code = 117 char = d;code = 100 char = e;code = 101 char = ;code = 32 char = 1;code = 49 char = 5;code = 53 char = 0;code = 48 char = ;code = 32 char = m;code = 109 char = );code = 41 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = s;code = 115 char = a;code = 97 char = m;code = 109 char = e;code = 101 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = b;code = 98 char = j;code = 106 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = s;code = 115 char = ;code = 32 char = w;code = 119 char = i;code = 105 char = t;code = 116 char = h;code = 104 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = 2;code = 50 char = 4;code = 52 char = ;code = 32 char = h;code = 104 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = a;code = 97 char = r;code = 114 char = r;code = 114 char = i;code = 105 char = v;code = 118 char = a;code = 97 char = l;code = 108 char = .;code = 46 char = ;code = 32 char = V;code = 86 char = a;code = 97 char = s;code = 115 char = o;code = 111 char = d;code = 100 char = i;code = 105 char = l;code = 108 char = a;code = 97 char = t;code = 116 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = m;code = 109 char = i;code = 105 char = d;code = 100 char = d;code = 100 char = l;code = 108 char = e;code = 101 char = ;code = 32 char = c;code = 99 char = e;code = 101 char = r;code = 114 char = e;code = 101 char = b;code = 98 char = r;code = 114 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = a;code = 97 char = r;code = 114 char = t;code = 116 char = e;code = 101 char = r;code = 114 char = y;code = 121 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = p;code = 112 char = p;code = 112 char = l;code = 108 char = y;code = 121 char = ;code = 32 char = t;code = 116 char = e;code = 101 char = r;code = 114 char = r;code = 114 char = i;code = 105 char = t;code = 116 char = o;code = 111 char = r;code = 114 char = y;code = 121 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = r;code = 114 char = e;code = 101 char = s;code = 115 char = p;code = 112 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = e;code = 101 char = ;code = 32 char = t;code = 116 char = o;code = 111 char = ;code = 32 char = C;code = 67 char = O;code = 79 char = 2;code = 50 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = N;code = 78 char = O;code = 79 char = ,;code = 44 char = ;code = 32 char = b;code = 98 char = o;code = 111 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = p;code = 112 char = h;code = 104 char = y;code = 121 char = s;code = 115 char = i;code = 105 char = o;code = 111 char = l;code = 108 char = o;code = 111 char = g;code = 103 char = i;code = 105 char = c;code = 99 char = ;code = 32 char = v;code = 118 char = a;code = 97 char = s;code = 115 char = o;code = 111 char = d;code = 100 char = i;code = 105 char = l;code = 108 char = a;code = 97 char = t;code = 116 char = o;code = 111 char = r;code = 114 char = s;code = 115 char = ,;code = 44 char = ;code = 32 char = i;code = 105 char = s;code = 115 char = ;code = 32 char = d;code = 100 char = e;code = 101 char = f;code = 102 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = e;code = 101 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = A;code = 65 char = n;code = 110 char = d;code = 100 char = e;code = 101 char = a;code = 97 char = n;code = 110 char = ;code = 32 char = n;code = 110 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = e;code = 101 char = s;code = 115 char = ;code = 32 char = a;code = 97 char = t;code = 116 char = ;code = 32 char = a;code = 97 char = l;code = 108 char = t;code = 116 char = i;code = 105 char = t;code = 116 char = u;code = 117 char = d;code = 100 char = e;code = 101 char = ;code = 32 char = a;code = 97 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = ;code = 32 char = s;code = 115 char = a;code = 97 char = m;code = 109 char = e;code = 101 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = b;code = 98 char = j;code = 106 char = e;code = 101 char = c;code = 99 char = t;code = 116 char = s;code = 115 char = ;code = 32 char = a;code = 97 char = t;code = 116 char = ;code = 32 char = s;code = 115 char = e;code = 101 char = a;code = 97 char = ;code = 32 char = l;code = 108 char = e;code = 101 char = v;code = 118 char = e;code = 101 char = l;code = 108 char = .;code = 46 char = ;code = 32 char = I;code = 73 char = n;code = 110 char = c;code = 99 char = a;code = 97 char = p;code = 112 char = a;code = 97 char = c;code = 99 char = i;code = 105 char = t;code = 116 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = n;code = 110 char = g;code = 103 char = ;code = 32 char = m;code = 109 char = i;code = 105 char = g;code = 103 char = r;code = 114 char = a;code = 97 char = i;code = 105 char = n;code = 110 char = e;code = 101 char = ;code = 32 char = c;code = 99 char = a;code = 97 char = n;code = 110 char = ;code = 32 char = o;code = 111 char = c;code = 99 char = c;code = 99 char = u;code = 117 char = r;code = 114 char = ;code = 32 char = w;code = 119 char = i;code = 105 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = i;code = 105 char = m;code = 109 char = p;code = 112 char = a;code = 97 char = i;code = 105 char = r;code = 114 char = e;code = 101 char = d;code = 100 char = ;code = 32 char = c;code = 99 char = e;code = 101 char = r;code = 114 char = e;code = 101 char = b;code = 98 char = r;code = 114 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = v;code = 118 char = a;code = 97 char = s;code = 115 char = o;code = 111 char = r;code = 114 char = e;code = 101 char = a;code = 97 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = v;code = 118 char = i;code = 105 char = t;code = 116 char = y;code = 121 char = ;code = 32 char = t;code = 116 char = o;code = 111 char = ;code = 32 char = p;code = 112 char = h;code = 104 char = y;code = 121 char = s;code = 115 char = i;code = 105 char = o;code = 111 char = l;code = 108 char = o;code = 111 char = g;code = 103 char = i;code = 105 char = c;code = 99 char = ;code = 32 char = v;code = 118 char = a;code = 97 char = s;code = 115 char = o;code = 111 char = d;code = 100 char = i;code = 105 char = l;code = 108 char = a;code = 97 char = t;code = 116 char = o;code = 111 char = r;code = 114 char = s;code = 115 char = .;code = 46 char = ;code = 32 char = W;code = 87 char = e;code = 101 char = ;code = 32 char = p;code = 112 char = r;code = 114 char = o;code = 111 char = p;code = 112 char = o;code = 111 char = s;code = 115 char = e;code = 101 char = ;code = 32 char = t;code = 116 char = h;code = 104 char = a;code = 97 char = t;code = 116 char = ;code = 32 char = s;code = 115 char = u;code = 117 char = s;code = 115 char = c;code = 99 char = e;code = 101 char = p;code = 112 char = t;code = 116 char = i;code = 105 char = b;code = 98 char = i;code = 105 char = l;code = 108 char = i;code = 105 char = t;code = 116 char = y;code = 121 char = ;code = 32 char = t;code = 116 char = o;code = 111 char = ;code = 32 char = m;code = 109 char = i;code = 105 char = g;code = 103 char = r;code = 114 char = a;code = 97 char = i;code = 105 char = n;code = 110 char = e;code = 101 char = ;code = 32 char = m;code = 109 char = i;code = 105 char = g;code = 103 char = h;code = 104 char = t;code = 116 char = ;code = 32 char = d;code = 100 char = e;code = 101 char = p;code = 112 char = e;code = 101 char = n;code = 110 char = d;code = 100 char = ;code = 32 char = i;code = 105 char = n;code = 110 char = ;code = 32 char = p;code = 112 char = a;code = 97 char = r;code = 114 char = t;code = 116 char = ;code = 32 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = g;code = 103 char = e;code = 101 char = n;code = 110 char = e;code = 101 char = ;code = 32 char = e;code = 101 char = x;code = 120 char = p;code = 112 char = r;code = 114 char = e;code = 101 char = s;code = 115 char = s;code = 115 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = ;code = 32 char = w;code = 119 char = i;code = 105 char = t;code = 116 char = h;code = 104 char = ;code = 32 char = c;code = 99 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = e;code = 101 char = q;code = 113 char = u;code = 117 char = e;code = 101 char = n;code = 110 char = t;code = 116 char = ;code = 32 char = a;code = 97 char = l;code = 108 char = t;code = 116 char = e;code = 101 char = r;code = 114 char = a;code = 97 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = s;code = 115 char = ;code = 32 char = o;code = 111 char = f;code = 102 char = ;code = 32 char = e;code = 101 char = n;code = 110 char = d;code = 100 char = o;code = 111 char = t;code = 116 char = h;code = 104 char = e;code = 101 char = l;code = 108 char = i;code = 105 char = a;code = 97 char = l;code = 108 char = ;code = 32 char = f;code = 102 char = u;code = 117 char = n;code = 110 char = c;code = 99 char = t;code = 116 char = i;code = 105 char = o;code = 111 char = n;code = 110 char = .;code = 46 char = <;code = 60 char = b;code = 98 char = r;code = 114 char = /;code = 47 char = >;code = 62 result sql = Headache is common in Cerro de Pasco (CP), Peru (altitude 4338 m) and was present in all patients with chronic mountain sickness (CMS) in CP reported here. Forty-seven percent of inhabitants report headache. Twenty-four percent of men have migraine with aura, with an average of 65 attacks a year. We assessed vasoreactivity of the cerebral vessels to CO2 by rebreathing and to NO by the administration of isosorbite dinitrate (IDN), a nitric oxide (NO) donor, using transcranial Doppler ultrasound in the middle cerebral artery (MCA) in natives of CP, some of whom suffered from CMS. We repeated the measurements in Lima (altitude 150 m) in the same subjects within 24 h of arrival. Vasodilatation in the middle cerebral artery supply territory in response to CO2 and NO, both physiologic vasodilators, is defective in Andean natives at altitude and in the same subjects at sea level. Incapacitating migraine can occur with impaired cerebral vasoreactivity to physiologic vasodilators. We propose that susceptibility to migraine might depend in part on gene expression with consequent alterations of endothelial function.
Publication: J. Neurol. Sci. 2004 Apr 15 ;219(1-2)::101-6.
Publication Date: 2004 Apr 15
Study Author(s): Appenzeller, O;Passino, C;Roach, R;Gamboa, J;Gamboa, A;Bernardi, L;Bonfichi, M;Malcovati, L;
Institution: NMHEMC Research Foundation, Otto Appenzeller, 361, Big Horn Ridge Drive NE, Albuquerque, NM 87122-1424, USA.
[email protected]
Shortcut link to this study:
Headache is common in Cerro de Pasco (CP), Peru (altitude 4338 m) and was present in all patients with chronic mountain sickness (CMS) in CP reported here. Forty-seven percent of inhabitants report headache. Twenty-four percent of men have migraine with aura, with an average of 65 attacks a year. We assessed vasoreactivity of the cerebral vessels to CO2 by rebreathing and to NO by the administration of isosorbite dinitrate (IDN), a nitric oxide (NO) donor, using transcranial Doppler ultrasound in the middle cerebral artery (MCA) in natives of CP, some of whom suffered from CMS. We repeated the measurements in Lima (altitude 150 m) in the same subjects within 24 h of arrival. Vasodilatation in the middle cerebral artery supply territory in response to CO2 and NO, both physiologic vasodilators, is defective in Andean natives at altitude and in the same subjects at sea level. Incapacitating migraine can occur with impaired cerebral vasoreactivity to physiologic vasodilators. We propose that susceptibility to migraine might depend in part on gene expression with consequent alterations of endothelial function.