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char = f;code = 102
char = f;code = 102
char = e;code = 101
char = c;code = 99
char = t;code = 116
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = C;code = 67
char = o;code = 111
char = C;code = 67
char = 1;code = 49
char = 2;code = 50
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = N;code = 78
char = i;code = 105
char = C;code = 67
char = l;code = 108
char = 2;code = 50
char = ;code = 32
char = o;code = 111
char = n;code = 110
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char = c;code = 99
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char = t;code = 116
char = r;code = 114
char = a;code = 97
char = t;code = 116
char = e;code = 101
char = ;code = 32
char = u;code = 117
char = p;code = 112
char = t;code = 116
char = a;code = 97
char = k;code = 107
char = e;code = 101
char = ;code = 32
char = b;code = 98
char = y;code = 121
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
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char = r;code = 114
char = a;code = 97
char = t;code = 116
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = n;code = 110
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = b;code = 98
char = r;code = 114
char = u;code = 117
char = s;code = 115
char = h;code = 104
char = ;code = 32
char = b;code = 98
char = o;code = 111
char = r;code = 114
char = d;code = 100
char = e;code = 101
char = r;code = 114
char = ;code = 32
char = m;code = 109
char = e;code = 101
char = m;code = 109
char = b;code = 98
char = r;code = 114
char = a;code = 97
char = n;code = 110
char = e;code = 101
char = .;code = 46
result sql = Direct effect of CoC12 and NiCl2 on citrate uptake by the rat renal brush border membrane.
Direct effect of CoC12 and NiCl2 on citrate uptake by the rat renal brush border membrane.
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char = e;code = 101
char = s;code = 115
char = s;code = 115
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char = T;code = 84
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char = (;code = 40
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char = B;code = 66
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char = B;code = 66
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result sql = Co and Ni are essential but relatively rare elements as to organisms. In the mammalian membrane, these metals are transported by the same carrier proteins. The aim of this study was to investigate the direct effects of CoCl2 and NiCl2 on citrate uptake by rat renal brush border membrane vesicles (BBMV) BBMV : were prepared by the divalent cation precipitation methods, and citrate uptake was measured by the Millipore rapid membrane filtration technique. The time course of citrate uptake during 120-min of incubation with 1 mM CoCl2 and NiCl2 showed a rapid significant inhibition at the early phase and a slight recover at the late phase. Incubation for 1 min of BBMV with 1, 5 and 25 mM CoCl2 and NiCl2, respectively, significantly inhibited citrate uptake in a concentration-dependent manner compared with that of 0 mM. We discuss these findings from the point of view that Co and Ni are located in Group VIII of the periodic table.

Publication: Ind Health 2005 Jul ;43(3)::574-9.
Publication Date: 2005 Jul
Study Author(s): Sato, Kazuhiro;Kusaka, Yukinori;Suganuma, Narufumi;Akino, Hironobu;Yokoyama, Osamu;
Institution: Department of Environmental Health, School of Medicine, University of Fukui, Fukui 910-1193, Japan.
Shortcut link to this study:
Co and Ni are essential but relatively rare elements as to organisms. In the mammalian membrane, these metals are transported by the same carrier proteins. The aim of this study was to investigate the direct effects of CoCl2 and NiCl2 on citrate uptake by rat renal brush border membrane vesicles (BBMV) BBMV : were prepared by the divalent cation precipitation methods, and citrate uptake was measured by the Millipore rapid membrane filtration technique. The time course of citrate uptake during 120-min of incubation with 1 mM CoCl2 and NiCl2 showed a rapid significant inhibition at the early phase and a slight recover at the late phase. Incubation for 1 min of BBMV with 1, 5 and 25 mM CoCl2 and NiCl2, respectively, significantly inhibited citrate uptake in a concentration-dependent manner compared with that of 0 mM. We discuss these findings from the point of view that Co and Ni are located in Group VIII of the periodic table.
PMID: 16100935

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