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result sql = Biophysical characterization of the non-fusogenic interaction between liposomes and the shrimp bifunctional lipoprotein-beta-glucan binding protein HDL/BGBP.
Biophysical characterization of the non-fusogenic interaction between liposomes and the shrimp bifunctional lipoprotein-beta-glucan binding protein HDL/BGBP.char = S;code = 83
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result sql = Shrimp High Density Lipoprotein-beta-Glucan Binding Protein (HDL/BGBP) has been studied by its role in nutrition and innate defense. Although the mechanisms of lipid loading are still unknown, HDL-BGBP binds and aggregates phospholipids vesicles in vitro. To gain insights into the HDL-BGBP mechanism of interaction with membranes, we have used fluorescence spectroscopy and electron microscopy. Data show that HDL-BGBP does not induce membrane fusion, leakage nor lipid exchange, although microstructural changes are clearly observed. This work supports a model where protein aggregation leads to liposome clustering. Such interaction may be a critical factor for the activation of the shrimp blood cell in vivo.
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result sql = Biophysical characterization of the non-fusogenic interaction between liposomes and the shrimp bifunctional lipoprotein-beta-glucan binding protein HDL/BGBP.
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result sql = Shrimp High Density Lipoprotein-beta-Glucan Binding Protein (HDL/BGBP) has been studied by its role in nutrition and innate defense. Although the mechanisms of lipid loading are still unknown, HDL-BGBP binds and aggregates phospholipids vesicles in vitro. To gain insights into the HDL-BGBP mechanism of interaction with membranes, we have used fluorescence spectroscopy and electron microscopy. Data show that HDL-BGBP does not induce membrane fusion, leakage nor lipid exchange, although microstructural changes are clearly observed. This work supports a model where protein aggregation leads to liposome clustering. Such interaction may be a critical factor for the activation of the shrimp blood cell in vivo.
Publication: Protein Pept. Lett. 2006 ;13(1)::71-5.
Publication Date: 2006
Study Author(s): Morán-Palacio, Edgar F;Tricerri, M Alejandra;García-Orozco, Karina;Romo-Figueroa, Maria Gabriela;Yepiz-Plascencia, Gloria;Garda, Horacio A;Sotelo-Mundo, Rogerio R;
Institution: Aquatic Molecular Biology Laboratory, Centro de Investigación en Alimentación y Desarrollo, A.C. PO Box 1735, Hermosillo Sonora, 83000 México.
Shortcut link to this study:
Publication Date: 2006
Study Author(s): Morán-Palacio, Edgar F;Tricerri, M Alejandra;García-Orozco, Karina;Romo-Figueroa, Maria Gabriela;Yepiz-Plascencia, Gloria;Garda, Horacio A;Sotelo-Mundo, Rogerio R;
Institution: Aquatic Molecular Biology Laboratory, Centro de Investigación en Alimentación y Desarrollo, A.C. PO Box 1735, Hermosillo Sonora, 83000 México.
Shortcut link to this study:
Shrimp High Density Lipoprotein-beta-Glucan Binding Protein (HDL/BGBP) has been studied by its role in nutrition and innate defense. Although the mechanisms of lipid loading are still unknown, HDL-BGBP binds and aggregates phospholipids vesicles in vitro. To gain insights into the HDL-BGBP mechanism of interaction with membranes, we have used fluorescence spectroscopy and electron microscopy. Data show that HDL-BGBP does not induce membrane fusion, leakage nor lipid exchange, although microstructural changes are clearly observed. This work supports a model where protein aggregation leads to liposome clustering. Such interaction may be a critical factor for the activation of the shrimp blood cell in vivo.
PMID: 16454673
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