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result sql = Expansion of altered vaginal flora states in vaginitis to include a spectrum of microflora.
Expansion of altered vaginal flora states in vaginitis to include a spectrum of microflora.
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char = e;code = 101
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char = e;code = 101
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char = m;code = 109
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char = h;code = 104
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char = s;code = 115
char = ;code = 32
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char = <;code = 60
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char = C;code = 67
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char = U;code = 85
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char = O;code = 79
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char = r;code = 114
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char = s;code = 115
char = s;code = 115
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char = t;code = 116
char = ;code = 32
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char = e;code = 101
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char = m;code = 109
char = p;code = 112
char = l;code = 108
char = i;code = 105
char = f;code = 102
char = i;code = 105
char = e;code = 101
char = s;code = 115
char = ;code = 32
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char = ;code = 32
char = i;code = 105
char = g;code = 103
char = n;code = 110
char = o;code = 111
char = r;code = 114
char = e;code = 101
char = s;code = 115
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = f;code = 102
char = u;code = 117
char = l;code = 108
char = l;code = 108
char = ;code = 32
char = s;code = 115
char = p;code = 112
char = e;code = 101
char = c;code = 99
char = t;code = 116
char = r;code = 114
char = u;code = 117
char = m;code = 109
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = a;code = 97
char = l;code = 108
char = t;code = 116
char = e;code = 101
char = r;code = 114
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = v;code = 118
char = a;code = 97
char = g;code = 103
char = i;code = 105
char = n;code = 110
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = m;code = 109
char = i;code = 105
char = c;code = 99
char = r;code = 114
char = o;code = 111
char = f;code = 102
char = l;code = 108
char = o;code = 111
char = r;code = 114
char = a;code = 97
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result sql = OBJECTIVE : To define the existence of 2 patterns of altered vaginal flora in symptomatic women identified on wet preparations that are not in the current vaginitis classification system.

STUDY DESIGN : Testing of vaginal secretions from gynecologic patients at Mayo Clinic, Scottsdale, Arizona, who presented with vulvo-vaginal symptoms by vaginal pH, whiff testing, and saline and potassium hydroxide wet preparations. Over 14 years, approximately 5,000 samples were analyzed. Wet preparations were analyzed under low- (x 100) and high-power (x 400) phase-contrast microscopy.

RESULTS : The first pattern has mixed bacteria with few or no lactobacilli, increased leukocytes and elevated pH. This pattern has a spectrum of severity, with the severe form meeting the diagnostic definition of desquamative inflammatory vaginitis. The mild-to-moderate form, termed inflammatory vaginitis, falls outside established diagnostic categories. The second pattern also has a spectrum of severity. The mild-to-moderate form, termed noninflammatory vaginosis, has mixed bacteria speckling squamous cells (but not obscuring edges), few or no lactobacilli, no leukocyte response and mildly elevated pH. This form differs from the severe form, which meets Amsel's criteria for bacterial vaginosis.

CONCLUSION : The current classification system requires revision because it oversimplifies and ignores the full spectrum of altered vaginal microflora.

Publication: J Reprod Med 2007 Feb ;52(2)::93-9.
Publication Date: 2007 Feb
Study Author(s): Fowler, R Stuart;
Institution: Department of Obstetrics and Gynecology, Mayo Clinic, Scottsdale, Arizona 85259, USA. fowler.stuart@mayo.edu
Shortcut link to this study:
OBJECTIVE : To define the existence of 2 patterns of altered vaginal flora in symptomatic women identified on wet preparations that are not in the current vaginitis classification system.

STUDY DESIGN : Testing of vaginal secretions from gynecologic patients at Mayo Clinic, Scottsdale, Arizona, who presented with vulvo-vaginal symptoms by vaginal pH, whiff testing, and saline and potassium hydroxide wet preparations. Over 14 years, approximately 5,000 samples were analyzed. Wet preparations were analyzed under low- (x 100) and high-power (x 400) phase-contrast microscopy.

RESULTS : The first pattern has mixed bacteria with few or no lactobacilli, increased leukocytes and elevated pH. This pattern has a spectrum of severity, with the severe form meeting the diagnostic definition of desquamative inflammatory vaginitis. The mild-to-moderate form, termed inflammatory vaginitis, falls outside established diagnostic categories. The second pattern also has a spectrum of severity. The mild-to-moderate form, termed noninflammatory vaginosis, has mixed bacteria speckling squamous cells (but not obscuring edges), few or no lactobacilli, no leukocyte response and mildly elevated pH. This form differs from the severe form, which meets Amsel's criteria for bacterial vaginosis.

CONCLUSION : The current classification system requires revision because it oversimplifies and ignores the full spectrum of altered vaginal microflora.
PMID: 17393768

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