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result sql = The prevalence of neonatal herpes simplex virus infection compared with serious bacterial illness in hospitalized neonates.
The prevalence of neonatal herpes simplex virus infection compared with serious bacterial illness in hospitalized neonates.char = <;code = 60
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result sql = OBJECTIVE : To determine the prevalence of herpes simplex virus (HSV) relative to other viral infections and serious bacterial illnesses (SBIs) in hospitalized neonates admitted from a pediatric emergency department over a 5-year period.
STUDY DESIGN : Retrospective prevalence study of laboratory-confirmed viral infections and culture-proven SBIs, with electronic databases and medical record review.
RESULTS : A total 5817 neonates were included: 8.4% with viral infection, 4.6% with SBIs. Of 960 neonates with documented fever, 17.2% had viral infections (0.3% HSV infection) and 14.2% had SBIs (1.3% bacterial meningitis). Of 204 neonates with fever and cerebrospinal fluid (CSF) pleocytosis, 1.0% had HSV infection and 5.4% had bacterial meningitis. Of 124 neonates with fever and mononuclear CSF pleocytosis, 1.6% had HSV and 0.8% had bacterial meningitis. Of 187 neonates with hypothermia, 1.1% had HSV infection presenting as a sepsis-like syndrome.
CONCLUSIONS : In febrile neonates admitted to the hospital from the emergency department, the prevalence of HSV infection was similar to that of bacterial meningitis, suggesting that HSV infection be considered in the differential diagnosis of neonatal fever, especially in the presence of mononuclear CSF pleocytosis. HSV infection should also be considered in neonates with hypothermia and a sepsis-like syndrome.
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result sql = The prevalence of neonatal herpes simplex virus infection compared with serious bacterial illness in hospitalized neonates.
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char = l;code = 108
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char = s;code = 115
char = e;code = 101
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char = a;code = 97
char = ;code = 32
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char = <;code = 60
char = b;code = 98
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char = S;code = 83
char = T;code = 84
char = U;code = 85
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char = Y;code = 89
char = ;code = 32
char = D;code = 68
char = E;code = 69
char = S;code = 83
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char = G;code = 71
char = N;code = 78
char = ;code = 32
char = :;code = 58
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char = <;code = 60
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char = b;code = 98
char = >;code = 62
char = R;code = 82
char = e;code = 101
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char = r;code = 114
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char = s;code = 115
char = p;code = 112
char = e;code = 101
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char = i;code = 105
char = v;code = 118
char = e;code = 101
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char = r;code = 114
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char = a;code = 97
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char = a;code = 97
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char = c;code = 99
char = o;code = 111
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char = r;code = 114
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char = l;code = 108
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char = i;code = 105
char = n;code = 110
char = f;code = 102
char = e;code = 101
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char = s;code = 115
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char = a;code = 97
char = n;code = 110
char = d;code = 100
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char = c;code = 99
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char = l;code = 108
char = t;code = 116
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char = r;code = 114
char = e;code = 101
char = -;code = 45
char = p;code = 112
char = r;code = 114
char = o;code = 111
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char = e;code = 101
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char = S;code = 83
char = B;code = 66
char = I;code = 73
char = s;code = 115
char = ,;code = 44
char = ;code = 32
char = w;code = 119
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char = c;code = 99
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char = a;code = 97
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char = a;code = 97
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char = a;code = 97
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char = e;code = 101
char = s;code = 115
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char = c;code = 99
char = a;code = 97
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char = c;code = 99
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char = r;code = 114
char = d;code = 100
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char = e;code = 101
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char = .;code = 46
char = <;code = 60
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char = >;code = 62
char = <;code = 60
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char = /;code = 47
char = >;code = 62
char = <;code = 60
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char = >;code = 62
char = R;code = 82
char = E;code = 69
char = S;code = 83
char = U;code = 85
char = L;code = 76
char = T;code = 84
char = S;code = 83
char = ;code = 32
char = :;code = 58
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char = <;code = 60
char = /;code = 47
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char = >;code = 62
char = A;code = 65
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char = o;code = 111
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char = a;code = 97
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char = 5;code = 53
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char = 1;code = 49
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char = e;code = 101
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char = %;code = 37
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char = .;code = 46
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char = H;code = 72
char = S;code = 83
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char = (;code = 40
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char = l;code = 108
char = u;code = 117
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char = C;code = 67
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char = F;code = 70
char = );code = 41
char = ;code = 32
char = p;code = 112
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char = s;code = 115
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char = H;code = 72
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char = O;code = 79
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char = O;code = 79
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char = 1;code = 49
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char = 7;code = 55
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char = >;code = 62
char = <;code = 60
char = b;code = 98
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char = C;code = 67
char = O;code = 79
char = N;code = 78
char = C;code = 67
char = L;code = 76
char = U;code = 85
char = S;code = 83
char = I;code = 73
char = O;code = 79
char = N;code = 78
char = S;code = 83
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
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char = f;code = 102
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char = a;code = 97
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result sql = OBJECTIVE : To determine the prevalence of herpes simplex virus (HSV) relative to other viral infections and serious bacterial illnesses (SBIs) in hospitalized neonates admitted from a pediatric emergency department over a 5-year period.
STUDY DESIGN : Retrospective prevalence study of laboratory-confirmed viral infections and culture-proven SBIs, with electronic databases and medical record review.
RESULTS : A total 5817 neonates were included: 8.4% with viral infection, 4.6% with SBIs. Of 960 neonates with documented fever, 17.2% had viral infections (0.3% HSV infection) and 14.2% had SBIs (1.3% bacterial meningitis). Of 204 neonates with fever and cerebrospinal fluid (CSF) pleocytosis, 1.0% had HSV infection and 5.4% had bacterial meningitis. Of 124 neonates with fever and mononuclear CSF pleocytosis, 1.6% had HSV and 0.8% had bacterial meningitis. Of 187 neonates with hypothermia, 1.1% had HSV infection presenting as a sepsis-like syndrome.
CONCLUSIONS : In febrile neonates admitted to the hospital from the emergency department, the prevalence of HSV infection was similar to that of bacterial meningitis, suggesting that HSV infection be considered in the differential diagnosis of neonatal fever, especially in the presence of mononuclear CSF pleocytosis. HSV infection should also be considered in neonates with hypothermia and a sepsis-like syndrome.
Publication: J. Pediatr. 2008 Aug ;153(2)::164-9. :doi: 10.1016/j.jpeds.2008.02.031.
Publication Date: 2008 Aug
Study Author(s): Caviness, A Chantal;Demmler, Gail J;Almendarez, Yvette;Selwyn, B J;
Institution: Section of Pediatric Emergency Medicine, Houston, TX, USA. [email protected]
Shortcut link to this study:
Publication Date: 2008 Aug
Study Author(s): Caviness, A Chantal;Demmler, Gail J;Almendarez, Yvette;Selwyn, B J;
Institution: Section of Pediatric Emergency Medicine, Houston, TX, USA. [email protected]
Shortcut link to this study:
OBJECTIVE : To determine the prevalence of herpes simplex virus (HSV) relative to other viral infections and serious bacterial illnesses (SBIs) in hospitalized neonates admitted from a pediatric emergency department over a 5-year period.
STUDY DESIGN : Retrospective prevalence study of laboratory-confirmed viral infections and culture-proven SBIs, with electronic databases and medical record review.
RESULTS : A total 5817 neonates were included: 8.4% with viral infection, 4.6% with SBIs. Of 960 neonates with documented fever, 17.2% had viral infections (0.3% HSV infection) and 14.2% had SBIs (1.3% bacterial meningitis). Of 204 neonates with fever and cerebrospinal fluid (CSF) pleocytosis, 1.0% had HSV infection and 5.4% had bacterial meningitis. Of 124 neonates with fever and mononuclear CSF pleocytosis, 1.6% had HSV and 0.8% had bacterial meningitis. Of 187 neonates with hypothermia, 1.1% had HSV infection presenting as a sepsis-like syndrome.
CONCLUSIONS : In febrile neonates admitted to the hospital from the emergency department, the prevalence of HSV infection was similar to that of bacterial meningitis, suggesting that HSV infection be considered in the differential diagnosis of neonatal fever, especially in the presence of mononuclear CSF pleocytosis. HSV infection should also be considered in neonates with hypothermia and a sepsis-like syndrome.
STUDY DESIGN : Retrospective prevalence study of laboratory-confirmed viral infections and culture-proven SBIs, with electronic databases and medical record review.
RESULTS : A total 5817 neonates were included: 8.4% with viral infection, 4.6% with SBIs. Of 960 neonates with documented fever, 17.2% had viral infections (0.3% HSV infection) and 14.2% had SBIs (1.3% bacterial meningitis). Of 204 neonates with fever and cerebrospinal fluid (CSF) pleocytosis, 1.0% had HSV infection and 5.4% had bacterial meningitis. Of 124 neonates with fever and mononuclear CSF pleocytosis, 1.6% had HSV and 0.8% had bacterial meningitis. Of 187 neonates with hypothermia, 1.1% had HSV infection presenting as a sepsis-like syndrome.
CONCLUSIONS : In febrile neonates admitted to the hospital from the emergency department, the prevalence of HSV infection was similar to that of bacterial meningitis, suggesting that HSV infection be considered in the differential diagnosis of neonatal fever, especially in the presence of mononuclear CSF pleocytosis. HSV infection should also be considered in neonates with hypothermia and a sepsis-like syndrome.
PMID: 18534225
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