|
|
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result sql = Efalizumab-induced guttate psoriasis. Successful management and re-treatment.
Efalizumab-induced guttate psoriasis. Successful management and re-treatment.char = P;code = 80
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char = c;code = 99
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char = t;code = 116
char = h;code = 104
char = e;code = 101
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char = s;code = 115
char = a;code = 97
char = m;code = 109
char = e;code = 101
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char = s;code = 115
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char = n;code = 110
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char = s;code = 115
char = .;code = 46
char = <;code = 60
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result sql = Psoriasis is a chronic, immunologically based inflammatory skin disease. Efalizumab (Raptiva) is a humanized monoclonal immunoglobulin G1 antibody that binds with high specificity and affinity to the alpha subunit of leucocyte function-asssociated antigen-1 (LFA-1) on the surface of T cells. Therefore, efalizumab is an effective biologic therapy for the long-term treatment of chronic moderate-to-severe plaque psoriasis. This drug demonstrated a good safety profile, whereas most adverse events were mild to moderate in severity. During efalizumab treatment, a small percentage of patients experienced protocol-defined psoriasis adverse events (e.g. worsening of psoriasis or the onset of new psoriasis morphologies). We present the case of a patient who experienced a new onset of guttate psoriasis and a mild worsening of pre-existing psoriatic lesions during treatment with efalizumab. Restarting with the same drug did not induce any adverse events.
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char = z;code = 122
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char = b;code = 98
char = -;code = 45
char = i;code = 105
char = n;code = 110
char = d;code = 100
char = u;code = 117
char = c;code = 99
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = g;code = 103
char = u;code = 117
char = t;code = 116
char = t;code = 116
char = a;code = 97
char = t;code = 116
char = e;code = 101
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char = p;code = 112
char = s;code = 115
char = o;code = 111
char = r;code = 114
char = i;code = 105
char = a;code = 97
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char = i;code = 105
char = s;code = 115
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char = S;code = 83
char = u;code = 117
char = c;code = 99
char = c;code = 99
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char = s;code = 115
char = f;code = 102
char = u;code = 117
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char = m;code = 109
char = a;code = 97
char = n;code = 110
char = a;code = 97
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char = e;code = 101
char = m;code = 109
char = e;code = 101
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char = a;code = 97
char = t;code = 116
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result sql = Efalizumab-induced guttate psoriasis. Successful management and re-treatment.
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result sql = Psoriasis is a chronic, immunologically based inflammatory skin disease. Efalizumab (Raptiva) is a humanized monoclonal immunoglobulin G1 antibody that binds with high specificity and affinity to the alpha subunit of leucocyte function-asssociated antigen-1 (LFA-1) on the surface of T cells. Therefore, efalizumab is an effective biologic therapy for the long-term treatment of chronic moderate-to-severe plaque psoriasis. This drug demonstrated a good safety profile, whereas most adverse events were mild to moderate in severity. During efalizumab treatment, a small percentage of patients experienced protocol-defined psoriasis adverse events (e.g. worsening of psoriasis or the onset of new psoriasis morphologies). We present the case of a patient who experienced a new onset of guttate psoriasis and a mild worsening of pre-existing psoriatic lesions during treatment with efalizumab. Restarting with the same drug did not induce any adverse events.
Publication: J Dermatolog Treat 2008 ;19(3)::182-4. :doi: 10.1080/09546630701691236.
Publication Date: 2008
Study Author(s): Balato, Anna;La Bella, Serena;Gaudiello, Francesca;Balato, Nicola;
Institution: Department of Dermatology, University of Naples Federico II, Naples, Italy. [email protected]
Shortcut link to this study:
Publication Date: 2008
Study Author(s): Balato, Anna;La Bella, Serena;Gaudiello, Francesca;Balato, Nicola;
Institution: Department of Dermatology, University of Naples Federico II, Naples, Italy. [email protected]
Shortcut link to this study:
Psoriasis is a chronic, immunologically based inflammatory skin disease. Efalizumab (Raptiva) is a humanized monoclonal immunoglobulin G1 antibody that binds with high specificity and affinity to the alpha subunit of leucocyte function-asssociated antigen-1 (LFA-1) on the surface of T cells. Therefore, efalizumab is an effective biologic therapy for the long-term treatment of chronic moderate-to-severe plaque psoriasis. This drug demonstrated a good safety profile, whereas most adverse events were mild to moderate in severity. During efalizumab treatment, a small percentage of patients experienced protocol-defined psoriasis adverse events (e.g. worsening of psoriasis or the onset of new psoriasis morphologies). We present the case of a patient who experienced a new onset of guttate psoriasis and a mild worsening of pre-existing psoriatic lesions during treatment with efalizumab. Restarting with the same drug did not induce any adverse events.
PMID: 18569275
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