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char = o;code = 111
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char = c;code = 99
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char = z;code = 122
char = e;code = 101
char = d;code = 100
char = ,;code = 44
char = ;code = 32
char = d;code = 100
char = o;code = 111
char = u;code = 117
char = b;code = 98
char = l;code = 108
char = e;code = 101
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char = b;code = 98
char = l;code = 108
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char = n;code = 110
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char = ,;code = 44
char = ;code = 32
char = p;code = 112
char = l;code = 108
char = a;code = 97
char = c;code = 99
char = e;code = 101
char = b;code = 98
char = o;code = 111
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char = c;code = 99
char = o;code = 111
char = n;code = 110
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char = r;code = 114
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char = l;code = 108
char = l;code = 108
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char = d;code = 100
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char = i;code = 105
char = n;code = 110
char = t;code = 116
char = e;code = 101
char = r;code = 114
char = v;code = 118
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = t;code = 116
char = r;code = 114
char = i;code = 105
char = a;code = 97
char = l;code = 108
char = .;code = 46
result sql = Fish oil n-3 polyunsaturated fatty acids selectively affect plasma cytokines and decrease illness in Thai schoolchildren: a randomized, double-blind, placebo-controlled intervention trial.
Fish oil n-3 polyunsaturated fatty acids selectively affect plasma cytokines and decrease illness in Thai schoolchildren: a randomized, double-blind, placebo-controlled intervention trial.
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char = T;code = 84
char = I;code = 73
char = V;code = 86
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char = ;code = 32
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char = ;code = 32
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char = i;code = 105
char = ;code = 32
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char = c;code = 99
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char = o;code = 111
char = o;code = 111
char = l;code = 108
char = c;code = 99
char = h;code = 104
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result sql = OBJECTIVE : To determine whether very long-chain n-3 polyunsaturated fatty acids (PUFAs) affect illness and selected plasma cytokines in schoolchildren.

STUDY DESIGN : Thai schoolchildren aged 9 to 12 years consumed milk containing placebo (soybean) oil (n = 86) or fish oil (n = 94) on 5 days per week for 6 months; the latter provided 200 mg eicosapentaenoic acid plus 1 g docosahexaenoic acid daily. Episodes and duration of illness were recorded, and plasma interleukin (IL)-2 receptor, IL-6, IL-10, and transforming growth factor (TGF)-beta1 concentrations and the fatty acid profile of plasma phosphatidylcholine determined.

RESULTS : After intervention, very long-chain n-3 PUFAs were higher in plasma phosphatidylcholine in the fish oil group than in the placebo group (P < .001). The fish oil group showed fewer episodes (P = .014) and shorter duration (P = .024) of illness (mainly upper respiratory tract) than the placebo group. Plasma IL-2 receptor, IL-10, and IL-6 were not affected by either treatment. Plasma TGF-beta1 increased in both groups, but the increase was smaller in the fish oil group, and at the end of supplementation TGF-beta1 concentration was lower in the fish oil group (P < .001).

CONCLUSIONS : Very long-chain n-3 PUFAs reduce illness, mainly infections, in healthy Thai schoolchildren.

Publication: J. Pediatr. 2009 Mar ;154(3)::391-5. :doi: 10.1016/j.jpeds.2008.09.014.
Publication Date: 2009 Mar
Study Author(s): Thienprasert, Alice;Samuhaseneetoo, Suched;Popplestone, Kathryn;West, Annette L;Miles, Elizabeth A;Calder, Philip C;
Institution: Faculty of Science, Silpakorn University, Nakornpathom, Thailand. [email protected]
Shortcut link to this study:
OBJECTIVE : To determine whether very long-chain n-3 polyunsaturated fatty acids (PUFAs) affect illness and selected plasma cytokines in schoolchildren.

STUDY DESIGN : Thai schoolchildren aged 9 to 12 years consumed milk containing placebo (soybean) oil (n = 86) or fish oil (n = 94) on 5 days per week for 6 months; the latter provided 200 mg eicosapentaenoic acid plus 1 g docosahexaenoic acid daily. Episodes and duration of illness were recorded, and plasma interleukin (IL)-2 receptor, IL-6, IL-10, and transforming growth factor (TGF)-beta1 concentrations and the fatty acid profile of plasma phosphatidylcholine determined.

RESULTS : After intervention, very long-chain n-3 PUFAs were higher in plasma phosphatidylcholine in the fish oil group than in the placebo group (P < .001). The fish oil group showed fewer episodes (P = .014) and shorter duration (P = .024) of illness (mainly upper respiratory tract) than the placebo group. Plasma IL-2 receptor, IL-10, and IL-6 were not affected by either treatment. Plasma TGF-beta1 increased in both groups, but the increase was smaller in the fish oil group, and at the end of supplementation TGF-beta1 concentration was lower in the fish oil group (P < .001).

CONCLUSIONS : Very long-chain n-3 PUFAs reduce illness, mainly infections, in healthy Thai schoolchildren.
PMID: 18930251

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