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char = l;code = 108
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char = f;code = 102
char = r;code = 114
char = o;code = 111
char = m;code = 109
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char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = Y;code = 89
char = a;code = 97
char = n;code = 110
char = e;code = 101
char = s;code = 115
char = h;code = 104
char = a;code = 97
char = ;code = 32
char = (;code = 40
char = P;code = 80
char = e;code = 101
char = r;code = 114
char = u;code = 117
char = );code = 41
char = :;code = 58
char = ;code = 32
char = e;code = 101
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char = a;code = 97
char = l;code = 108
char = u;code = 117
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = l;code = 108
char = e;code = 101
char = i;code = 105
char = s;code = 115
char = h;code = 104
char = m;code = 109
char = a;code = 97
char = n;code = 110
char = i;code = 105
char = c;code = 99
char = i;code = 105
char = d;code = 100
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = t;code = 116
char = i;code = 105
char = m;code = 109
char = a;code = 97
char = l;code = 108
char = a;code = 97
char = r;code = 114
char = i;code = 105
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = a;code = 97
char = c;code = 99
char = t;code = 116
char = i;code = 105
char = v;code = 118
char = i;code = 105
char = t;code = 116
char = y;code = 121
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = s;code = 115
char = e;code = 101
char = l;code = 108
char = e;code = 101
char = c;code = 99
char = t;code = 116
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = e;code = 101
char = x;code = 120
char = t;code = 116
char = r;code = 114
char = a;code = 97
char = c;code = 99
char = t;code = 116
char = s;code = 115
char = .;code = 46
result sql = Medicinal plants from the Yanesha (Peru): evaluation of the leishmanicidal and antimalarial activity of selected extracts.
Medicinal plants from the Yanesha (Peru): evaluation of the leishmanicidal and antimalarial activity of selected extracts.
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char = U;code = 85
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char = ;code = 32
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char = <;code = 60
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char = l;code = 108
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char = ;code = 32
char = A;code = 65
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char = a;code = 97
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char = o;code = 111
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char = f;code = 102
char = e;code = 101
char = c;code = 99
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char = s;code = 115
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char = ;code = 32
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char = l;code = 108
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char = L;code = 76
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char = <;code = 60
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char = H;code = 72
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char = ;code = 32
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char = a;code = 97
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char = t;code = 116
char = i;code = 105
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char = T;code = 84
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char = z;code = 122
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char = t;code = 116
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char = o;code = 111
char = ;code = 32
char = Z;code = 90
char = i;code = 105
char = n;code = 110
char = g;code = 103
char = i;code = 105
char = b;code = 98
char = e;code = 101
char = r;code = 114
char = a;code = 97
char = c;code = 99
char = e;code = 101
char = a;code = 97
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char = ;code = 32
char = R;code = 82
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char = e;code = 101
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char = l;code = 108
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char = a;code = 97
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char = y;code = 121
char = r;code = 114
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char = o;code = 111
char = i;code = 105
char = d;code = 100
char = e;code = 101
char = a;code = 97
char = ;code = 32
char = (;code = 40
char = R;code = 82
char = u;code = 117
char = i;code = 105
char = z;code = 122
char = ;code = 32
char = &;code = 38
char = ;code = 32
char = P;code = 80
char = a;code = 97
char = v;code = 118
char = o;code = 111
char = n;code = 110
char = );code = 41
char = ;code = 32
char = P;code = 80
char = o;code = 111
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char = p;code = 112
char = .;code = 46
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char = &;code = 38
char = ;code = 32
char = E;code = 69
char = n;code = 110
char = d;code = 100
char = l;code = 108
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char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = R;code = 82
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char = e;code = 101
char = a;code = 97
char = l;code = 108
char = m;code = 109
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char = a;code = 97
char = ;code = 32
char = a;code = 97
char = l;code = 108
char = p;code = 112
char = i;code = 105
char = n;code = 110
char = i;code = 105
char = a;code = 97
char = ;code = 32
char = (;code = 40
char = R;code = 82
char = o;code = 111
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char = ,;code = 44
char = ;code = 32
char = t;code = 116
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char = o;code = 111
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char = P;code = 80
char = i;code = 105
char = p;code = 112
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char = P;code = 80
char = i;code = 105
char = p;code = 112
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char = a;code = 97
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char = u;code = 117
char = n;code = 110
char = c;code = 99
char = u;code = 117
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char = .;code = 46
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char = d;code = 100
char = ;code = 32
char = P;code = 80
char = i;code = 105
char = p;code = 112
char = e;code = 101
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char = ;code = 32
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char = e;code = 101
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char = e;code = 101
char = s;code = 115
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char = A;code = 65
char = u;code = 117
char = b;code = 98
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char = .;code = 46
char = );code = 41
char = ;code = 32
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char = .;code = 46
char = ;code = 32
char = D;code = 68
char = o;code = 111
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char = ;code = 32
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char = B;code = 66
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char = n;code = 110
char = o;code = 111
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char = i;code = 105
char = a;code = 97
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char = e;code = 101
char = a;code = 97
char = e;code = 101
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char = .;code = 46
char = ;code = 32
char = E;code = 69
char = i;code = 105
char = g;code = 103
char = h;code = 104
char = t;code = 116
char = ;code = 32
char = s;code = 115
char = p;code = 112
char = e;code = 101
char = c;code = 99
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char = e;code = 101
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char = s;code = 115
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char = t;code = 116
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char = n;code = 110
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char = ;code = 32
char = l;code = 108
char = e;code = 101
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char = s;code = 115
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char = a;code = 97
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char = t;code = 116
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char = 0;code = 48
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char = i;code = 105
char = c;code = 99
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char = a;code = 97
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char = a;code = 97
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char = p;code = 112
char = a;code = 97
char = p;code = 112
char = a;code = 97
char = y;code = 121
char = a;code = 97
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char = L;code = 76
char = .;code = 46
char = ;code = 32
char = (;code = 40
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char = a;code = 97
char = r;code = 114
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char = i;code = 105
char = p;code = 112
char = e;code = 101
char = r;code = 114
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char = e;code = 101
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char = n;code = 110
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char = s;code = 115
char = i;code = 105
char = i;code = 105
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char = T;code = 84
char = r;code = 114
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char = l;code = 108
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char = (;code = 40
char = P;code = 80
char = i;code = 105
char = p;code = 112
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char = m;code = 109
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char = a;code = 97
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char = J;code = 74
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char = ;code = 32
char = K;code = 75
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char = 6;code = 54
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char = g;code = 103
char = ;code = 32
char = (;code = 40
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char = i;code = 105
char = n;code = 110
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char = i;code = 105
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char = e;code = 101
char = r;code = 114
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char = ,;code = 44
char = ;code = 32
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char = e;code = 101
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char = t;code = 116
char = r;code = 114
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char = a;code = 97
char = c;code = 99
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char = o;code = 111
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char = u;code = 117
char = m;code = 109
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char = R;code = 82
char = u;code = 117
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char = &;code = 38
char = ;code = 32
char = P;code = 80
char = a;code = 97
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char = .;code = 46
char = ;code = 32
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char = S;code = 83
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char = a;code = 97
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char = a;code = 97
char = c;code = 99
char = e;code = 101
char = a;code = 97
char = e;code = 101
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char = ,;code = 44
char = ;code = 32
char = R;code = 82
char = e;code = 101
char = n;code = 110
char = e;code = 101
char = a;code = 97
char = l;code = 108
char = m;code = 109
char = i;code = 105
char = a;code = 97
char = ;code = 32
char = a;code = 97
char = l;code = 108
char = p;code = 112
char = i;code = 105
char = n;code = 110
char = i;code = 105
char = a;code = 97
char = ;code = 32
char = (;code = 40
char = R;code = 82
char = o;code = 111
char = t;code = 116
char = t;code = 116
char = b;code = 98
char = .;code = 46
char = );code = 41
char = ;code = 32
char = Z;code = 90
char = i;code = 105
char = n;code = 110
char = g;code = 103
char = i;code = 105
char = b;code = 98
char = e;code = 101
char = r;code = 114
char = a;code = 97
char = c;code = 99
char = e;code = 101
char = a;code = 97
char = e;code = 101
char = ,;code = 44
char = ;code = 32
char = L;code = 76
char = a;code = 97
char = n;code = 110
char = t;code = 116
char = a;code = 97
char = n;code = 110
char = a;code = 97
char = ;code = 32
char = s;code = 115
char = p;code = 112
char = .;code = 46
char = ;code = 32
char = (;code = 40
char = V;code = 86
char = e;code = 101
char = r;code = 114
char = b;code = 98
char = e;code = 101
char = n;code = 110
char = a;code = 97
char = c;code = 99
char = e;code = 101
char = a;code = 97
char = e;code = 101
char = );code = 41
char = ,;code = 44
char = ;code = 32
char = H;code = 72
char = y;code = 121
char = p;code = 112
char = t;code = 116
char = i;code = 105
char = s;code = 115
char = ;code = 32
char = l;code = 108
char = a;code = 97
char = c;code = 99
char = u;code = 117
char = s;code = 115
char = t;code = 116
char = r;code = 114
char = i;code = 105
char = s;code = 115
char = ;code = 32
char = A;code = 65
char = .;code = 46
char = ;code = 32
char = S;code = 83
char = t;code = 116
char = .;code = 46
char = -;code = 45
char = H;code = 72
char = i;code = 105
char = l;code = 108
char = .;code = 46
char = ;code = 32
char = e;code = 101
char = x;code = 120
char = ;code = 32
char = B;code = 66
char = e;code = 101
char = n;code = 110
char = t;code = 116
char = h;code = 104
char = .;code = 46
char = ;code = 32
char = (;code = 40
char = L;code = 76
char = a;code = 97
char = m;code = 109
char = i;code = 105
char = a;code = 97
char = c;code = 99
char = e;code = 101
char = a;code = 97
char = e;code = 101
char = );code = 41
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = C;code = 67
char = a;code = 97
char = l;code = 108
char = e;code = 101
char = a;code = 97
char = ;code = 32
char = m;code = 109
char = o;code = 111
char = n;code = 110
char = t;code = 116
char = a;code = 97
char = n;code = 110
char = a;code = 97
char = ;code = 32
char = K;code = 75
char = l;code = 108
char = a;code = 97
char = t;code = 116
char = .;code = 46
char = ;code = 32
char = (;code = 40
char = A;code = 65
char = s;code = 115
char = t;code = 116
char = e;code = 101
char = r;code = 114
char = a;code = 97
char = c;code = 99
char = e;code = 101
char = a;code = 97
char = e;code = 101
char = );code = 41
char = .;code = 46
char = ;code = 32
char = M;code = 77
char = o;code = 111
char = s;code = 115
char = t;code = 116
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = m;code = 109
char = ;code = 32
char = a;code = 97
char = r;code = 114
char = e;code = 101
char = ;code = 32
char = u;code = 117
char = s;code = 115
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = a;code = 97
char = g;code = 103
char = a;code = 97
char = i;code = 105
char = n;code = 110
char = s;code = 115
char = t;code = 116
char = ;code = 32
char = s;code = 115
char = k;code = 107
char = i;code = 105
char = n;code = 110
char = ;code = 32
char = a;code = 97
char = f;code = 102
char = f;code = 102
char = e;code = 101
char = c;code = 99
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = s;code = 115
char = ;code = 32
char = b;code = 98
char = y;code = 121
char = ;code = 32
char = Y;code = 89
char = a;code = 97
char = n;code = 110
char = e;code = 101
char = s;code = 115
char = h;code = 104
char = a;code = 97
char = ;code = 32
char = p;code = 112
char = e;code = 101
char = o;code = 111
char = p;code = 112
char = l;code = 108
char = e;code = 101
char = .;code = 46
char = ;code = 32
char = R;code = 82
char = e;code = 101
char = s;code = 115
char = u;code = 117
char = l;code = 108
char = t;code = 116
char = s;code = 115
char = ;code = 32
char = a;code = 97
char = r;code = 114
char = e;code = 101
char = ;code = 32
char = d;code = 100
char = i;code = 105
char = s;code = 115
char = c;code = 99
char = u;code = 117
char = s;code = 115
char = s;code = 115
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = h;code = 104
char = e;code = 101
char = r;code = 114
char = e;code = 101
char = i;code = 105
char = n;code = 110
char = ,;code = 44
char = ;code = 32
char = a;code = 97
char = c;code = 99
char = c;code = 99
char = o;code = 111
char = r;code = 114
char = d;code = 100
char = i;code = 105
char = n;code = 110
char = g;code = 103
char = ;code = 32
char = t;code = 116
char = o;code = 111
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = t;code = 116
char = r;code = 114
char = a;code = 97
char = d;code = 100
char = i;code = 105
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = u;code = 117
char = s;code = 115
char = e;code = 101
char = ;code = 32
char = o;code = 111
char = f;code = 102
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = p;code = 112
char = l;code = 108
char = a;code = 97
char = n;code = 110
char = t;code = 116
char = s;code = 115
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = c;code = 99
char = o;code = 111
char = m;code = 109
char = p;code = 112
char = a;code = 97
char = r;code = 114
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = w;code = 119
char = i;code = 105
char = t;code = 116
char = h;code = 104
char = ;code = 32
char = d;code = 100
char = a;code = 97
char = t;code = 116
char = a;code = 97
char = ;code = 32
char = o;code = 111
char = b;code = 98
char = t;code = 116
char = a;code = 97
char = i;code = 105
char = n;code = 110
char = e;code = 101
char = d;code = 100
char = ;code = 32
char = f;code = 102
char = r;code = 114
char = o;code = 111
char = m;code = 109
char = ;code = 32
char = t;code = 116
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = l;code = 108
char = i;code = 105
char = t;code = 116
char = e;code = 101
char = r;code = 114
char = a;code = 97
char = t;code = 116
char = u;code = 117
char = r;code = 114
char = e;code = 101
char = .;code = 46
result sql = AIM OF THE STUDY : Ninety-four ethanolic extracts of plants used medicinally by the Yanesha, an Amazonian Peruvian ethnic group, for affections related to leishmaniasis and malaria were screened in vitro against Leishmania amazonensis amastigotes and against a Plasmodium falciparum chloroquine resistant strain.

MATERIALS AND METHODS : The viability of Leishmania amazonensis amastigote stages was assessed by the reduction of tetrazolium salt (MTT) while the impact on Plasmodium falciparum was determined by measuring the incorporation of radio-labelled hypoxanthine.

RESULTS AND CONCLUSIONS : Six plant species displayed good activity against Plasmodium falciparum chloroquine resistant strain (IC(50) < 10 microg/ml): a Monimiaceae, Siparuna aspera (Ruiz & Pavon), A. DC., two Zingiberaceae, Renealmia thyrsoidea (Ruiz & Pavon) Poepp. & Endl. and Renealmia alpinia (Rottb.), two Piperaceae (Piper aduncum L. and Piper sp.) and the leaves of Jacaranda copaia (Aubl.) D. Don (Bignoniaceae). Eight species displayed interesting leishmanicidal activities (IC50 < 10 microg/ml): Carica papaya L. (Caricaceae), Piper dennisii Trel (Piperaceae), Hedychium coronarium J. König (Zingiberaceae), Cestrum racemosum Ruiz & Pav. (Solanaceae), Renealmia alpinia (Rottb.) Zingiberaceae, Lantana sp. (Verbenaceae), Hyptis lacustris A. St.-Hil. ex Benth. (Lamiaceae) and Calea montana Klat. (Asteraceae). Most of them are used against skin affections by Yanesha people. Results are discussed herein, according to the traditional use of the plants and compared with data obtained from the literature.

Publication: J Ethnopharmacol 2009 Jun 25 ;123(3)::413-22.
Publication Date: 2009 Jun 25
Study Author(s): Valadeau, Céline;Pabon, Adriana;Deharo, Eric;Albán-Castillo, Joaquina;Estevez, Yannick;Lores, Fransis Augusto;Rojas, Rosario;Gamboa, Dionicia;Sauvain, Michel;Castillo, Denis;Bourdy, Geneviève;
Institution: IFEA UMIFRE 17 CNRS/MAEE, Casilla 18-1217, Lima, Peru.
Shortcut link to this study:
AIM OF THE STUDY : Ninety-four ethanolic extracts of plants used medicinally by the Yanesha, an Amazonian Peruvian ethnic group, for affections related to leishmaniasis and malaria were screened in vitro against Leishmania amazonensis amastigotes and against a Plasmodium falciparum chloroquine resistant strain.

MATERIALS AND METHODS : The viability of Leishmania amazonensis amastigote stages was assessed by the reduction of tetrazolium salt (MTT) while the impact on Plasmodium falciparum was determined by measuring the incorporation of radio-labelled hypoxanthine.

RESULTS AND CONCLUSIONS : Six plant species displayed good activity against Plasmodium falciparum chloroquine resistant strain (IC(50) < 10 microg/ml): a Monimiaceae, Siparuna aspera (Ruiz & Pavon), A. DC., two Zingiberaceae, Renealmia thyrsoidea (Ruiz & Pavon) Poepp. & Endl. and Renealmia alpinia (Rottb.), two Piperaceae (Piper aduncum L. and Piper sp.) and the leaves of Jacaranda copaia (Aubl.) D. Don (Bignoniaceae). Eight species displayed interesting leishmanicidal activities (IC50 < 10 microg/ml): Carica papaya L. (Caricaceae), Piper dennisii Trel (Piperaceae), Hedychium coronarium J. König (Zingiberaceae), Cestrum racemosum Ruiz & Pav. (Solanaceae), Renealmia alpinia (Rottb.) Zingiberaceae, Lantana sp. (Verbenaceae), Hyptis lacustris A. St.-Hil. ex Benth. (Lamiaceae) and Calea montana Klat. (Asteraceae). Most of them are used against skin affections by Yanesha people. Results are discussed herein, according to the traditional use of the plants and compared with data obtained from the literature.
PMID: 19514108

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