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char = .;code = 46
result sql = Varicella pneumonia in southern Israel: clinical characteristics, diagnosis and therapeutic considerations.
Varicella pneumonia in southern Israel: clinical characteristics, diagnosis and therapeutic considerations.
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char = m;code = 109
char = p;code = 112
char = l;code = 108
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char = e;code = 101
char = ;code = 32
char = r;code = 114
char = e;code = 101
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result sql = BACKGROUND : The most common and most serious complication of varicella (chickenpox) in adults is pneumonia, which can lead to severe respiratory failure. Varicella pneumonia is associated with considerable morbidity and even death.

OBJECTIVES : To summarize our experience with varicella pneumonia in terms of clinical, laboratory and radiological characteristics as well as risk factors, management and outcome.

METHODS : We conducted a retrospective cohort survey in our facility from 1995 to 2008.

RESULTS : Our cohort comprised 21 patients with varicella pneumonia, of whom 19 (90%) were men; their mean age was 35 +/- 10.5 years. Nineteen patients (90%) were Bedouins and 18 (86%) were smokers. Eleven (52%) were admitted to the Medical Intensive Care Unit; 3 of them required mechanical ventilation and the remaining 10 (48%) were admitted to the general medical ward. Median length of stay was 6 +/- 7.7 days. Hypoxemia and elevated lactate dehydrogenase on admission were associated with respiratory failure. Radiological manifestations were variable and nine patients exhibited characteristic findings. All but one patient were treated with acyclovir. All patients fully recovered. Conclusions: In southern Israel varicella pneumonia is primarily a disease ofyoung male Bedouins who are smokers. Severity ranges from mild disease to severe, resulting at times in respiratory failure requiring mechanical ventilation. Prognosis is favorable with complete recovery.

Publication: Isr. Med. Assoc. J. 2009 May ;11(5)::261-5.
Publication Date: 2009 May
Study Author(s): Avnon, Lone S;Smolikov, Alexander;Almog, Yaniv;
Institution: Division of Pulmonary Medicine, Soroka University Medical Center and Faculty of Health Sciences, Beer Sheva, Israel.
Shortcut link to this study:
BACKGROUND : The most common and most serious complication of varicella (chickenpox) in adults is pneumonia, which can lead to severe respiratory failure. Varicella pneumonia is associated with considerable morbidity and even death.

OBJECTIVES : To summarize our experience with varicella pneumonia in terms of clinical, laboratory and radiological characteristics as well as risk factors, management and outcome.

METHODS : We conducted a retrospective cohort survey in our facility from 1995 to 2008.

RESULTS : Our cohort comprised 21 patients with varicella pneumonia, of whom 19 (90%) were men; their mean age was 35 +/- 10.5 years. Nineteen patients (90%) were Bedouins and 18 (86%) were smokers. Eleven (52%) were admitted to the Medical Intensive Care Unit; 3 of them required mechanical ventilation and the remaining 10 (48%) were admitted to the general medical ward. Median length of stay was 6 +/- 7.7 days. Hypoxemia and elevated lactate dehydrogenase on admission were associated with respiratory failure. Radiological manifestations were variable and nine patients exhibited characteristic findings. All but one patient were treated with acyclovir. All patients fully recovered. Conclusions: In southern Israel varicella pneumonia is primarily a disease ofyoung male Bedouins who are smokers. Severity ranges from mild disease to severe, resulting at times in respiratory failure requiring mechanical ventilation. Prognosis is favorable with complete recovery.
PMID: 19637501

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