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char = f;code = 102
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result sql = Effects of ultraviolet radiation on the kinetics of in vitro percutaneous absorption of lavender oil.
Effects of ultraviolet radiation on the kinetics of in vitro percutaneous absorption of lavender oil.
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char = s;code = 115
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result sql = The purpose of the present study is to investigate the influence of ultraviolet radiation on the rat skin absorption of lavender essential oil. The pure oil was extracted from Lavandula angustifolia by steam distillation. The chemical composition of lavender oil showed that terpenes are major compounds. In vitro, the essential oil was applied onto the rat skin. The amount of the compounds was determined using gas chromatography. Similarly, the amount of these compounds was analyzed for the skin exposed to ultraviolet radiation (UVAI) after 4, 8, 12 and 24 h. Our study demonstrated that the penetration profiles showed a cycle of charge-discharge (4 h/4 h, respectively). Our data point to the presence of reversible change in stratum corneum behavior. Interestingly, the ultraviolet radiation altered the cycle (charge-discharge) for terpenes (low lipophilicity) and increased the charge time. However, for terpenes (high lipophilicity), the ultraviolet radiation decreased the charge amplitude.

Publication: Int J Pharm 2009 Dec 1 ;382(1-2)::33-8. :doi: 10.1016/j.ijpharm.2009.07.037.
Publication Date: 2009 Dec 1
Study Author(s): Ben Salah, Myriam;Abderraba, Manef;Tarhouni, Mohamed Radhouane;Abdelmelek, Hafedh;
Institution: Faculté des Sciences de Bizerte, Laboratoire de Physiologie Intégrée, 7021 Jarzouna, Tunisia. [email protected]
Shortcut link to this study:
The purpose of the present study is to investigate the influence of ultraviolet radiation on the rat skin absorption of lavender essential oil. The pure oil was extracted from Lavandula angustifolia by steam distillation. The chemical composition of lavender oil showed that terpenes are major compounds. In vitro, the essential oil was applied onto the rat skin. The amount of the compounds was determined using gas chromatography. Similarly, the amount of these compounds was analyzed for the skin exposed to ultraviolet radiation (UVAI) after 4, 8, 12 and 24 h. Our study demonstrated that the penetration profiles showed a cycle of charge-discharge (4 h/4 h, respectively). Our data point to the presence of reversible change in stratum corneum behavior. Interestingly, the ultraviolet radiation altered the cycle (charge-discharge) for terpenes (low lipophilicity) and increased the charge time. However, for terpenes (high lipophilicity), the ultraviolet radiation decreased the charge amplitude.
PMID: 19683042

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