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result sql = Functional imaging in differentiating bronchial masses: an initial experience with a combination of (18)F-FDG PET-CT scan and (68)Ga DOTA-TOC PET-CT scan.
Functional imaging in differentiating bronchial masses: an initial experience with a combination of (18)F-FDG PET-CT scan and (68)Ga DOTA-TOC PET-CT scan.
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char = r;code = 114
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char = >;code = 62
char = <;code = 60
char = b;code = 98
char = r;code = 114
char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
char = >;code = 62
char = R;code = 82
char = E;code = 69
char = S;code = 83
char = U;code = 85
char = L;code = 76
char = T;code = 84
char = S;code = 83
char = ;code = 32
char = :;code = 58
char = ;code = 32
char = <;code = 60
char = /;code = 47
char = b;code = 98
char = >;code = 62
char = H;code = 72
char = i;code = 105
char = s;code = 115
char = t;code = 116
char = o;code = 111
char = p;code = 112
char = a;code = 97
char = t;code = 116
char = h;code = 104
char = o;code = 111
char = l;code = 108
char = o;code = 111
char = g;code = 103
char = i;code = 105
char = c;code = 99
char = a;code = 97
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char = n;code = 110
char = a;code = 97
char = t;code = 116
char = i;code = 105
char = o;code = 111
char = n;code = 110
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = 7;code = 55
char = ;code = 32
char = b;code = 98
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char = h;code = 104
char = i;code = 105
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = m;code = 109
char = a;code = 97
char = s;code = 115
char = s;code = 115
char = e;code = 101
char = s;code = 115
char = ;code = 32
char = r;code = 114
char = e;code = 101
char = v;code = 118
char = e;code = 101
char = a;code = 97
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char = e;code = 101
char = d;code = 100
char = ;code = 32
char = c;code = 99
char = a;code = 97
char = r;code = 114
char = c;code = 99
char = i;code = 105
char = n;code = 110
char = o;code = 111
char = i;code = 105
char = d;code = 100
char = ;code = 32
char = t;code = 116
char = u;code = 117
char = m;code = 109
char = o;code = 111
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char = s;code = 115
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char = 2;code = 50
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char = t;code = 116
char = y;code = 121
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char = c;code = 99
char = a;code = 97
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char = 1;code = 49
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char = a;code = 97
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char = c;code = 99
char = a;code = 97
char = l;code = 108
char = );code = 41
char = ,;code = 44
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char = i;code = 105
char = n;code = 110
char = f;code = 102
char = l;code = 108
char = a;code = 97
char = m;code = 109
char = m;code = 109
char = a;code = 97
char = t;code = 116
char = o;code = 111
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char = y;code = 121
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char = m;code = 109
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char = o;code = 111
char = f;code = 102
char = i;code = 105
char = b;code = 98
char = r;code = 114
char = o;code = 111
char = b;code = 98
char = l;code = 108
char = a;code = 97
char = s;code = 115
char = t;code = 116
char = i;code = 105
char = c;code = 99
char = ;code = 32
char = t;code = 116
char = u;code = 117
char = m;code = 109
char = o;code = 111
char = r;code = 114
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char = (;code = 40
char = 1;code = 49
char = );code = 41
char = ,;code = 44
char = ;code = 32
char = m;code = 109
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char = c;code = 99
char = o;code = 111
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char = p;code = 112
char = i;code = 105
char = d;code = 100
char = e;code = 101
char = r;code = 114
char = m;code = 109
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char = d;code = 100
char = ;code = 32
char = c;code = 99
char = a;code = 97
char = r;code = 114
char = c;code = 99
char = i;code = 105
char = n;code = 110
char = o;code = 111
char = m;code = 109
char = a;code = 97
char = ;code = 32
char = (;code = 40
char = 1;code = 49
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char = ,;code = 44
char = ;code = 32
char = h;code = 104
char = a;code = 97
char = m;code = 109
char = a;code = 97
char = r;code = 114
char = t;code = 116
char = o;code = 111
char = m;code = 109
char = a;code = 97
char = ;code = 32
char = (;code = 40
char = 1;code = 49
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char = ,;code = 44
char = ;code = 32
char = a;code = 97
char = n;code = 110
char = d;code = 100
char = ;code = 32
char = s;code = 115
char = y;code = 121
char = n;code = 110
char = o;code = 111
char = v;code = 118
char = i;code = 105
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = c;code = 99
char = e;code = 101
char = l;code = 108
char = l;code = 108
char = ;code = 32
char = s;code = 115
char = a;code = 97
char = r;code = 114
char = c;code = 99
char = o;code = 111
char = m;code = 109
char = a;code = 97
char = ;code = 32
char = (;code = 40
char = 1;code = 49
char = );code = 41
char = .;code = 46
char = ;code = 32
char = T;code = 84
char = h;code = 104
char = e;code = 101
char = ;code = 32
char = t;code = 116
char = y;code = 121
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char = i;code = 105
char = c;code = 99
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = c;code = 99
char = a;code = 97
char = r;code = 114
char = c;code = 99
char = i;code = 105
char = n;code = 110
char = o;code = 111
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char = d;code = 100
char = s;code = 115
char = ;code = 32
char = h;code = 104
char = a;code = 97
char = d;code = 100
char = ;code = 32
char = m;code = 109
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char = l;code = 108
char = d;code = 100
char = ;code = 32
char = (;code = 40
char = 1;code = 49
char = 8;code = 56
char = );code = 41
char = F;code = 70
char = -;code = 45
char = F;code = 70
char = D;code = 68
char = G;code = 71
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char = u;code = 117
char = p;code = 112
char = t;code = 116
char = a;code = 97
char = k;code = 107
char = e;code = 101
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char = a;code = 97
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char = d;code = 100
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char = h;code = 104
char = i;code = 105
char = g;code = 103
char = h;code = 104
char = ;code = 32
char = (;code = 40
char = 6;code = 54
char = 8;code = 56
char = );code = 41
char = G;code = 71
char = a;code = 97
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char = D;code = 68
char = O;code = 79
char = T;code = 84
char = A;code = 65
char = -;code = 45
char = T;code = 84
char = O;code = 79
char = C;code = 67
char = ;code = 32
char = u;code = 117
char = p;code = 112
char = t;code = 116
char = a;code = 97
char = k;code = 107
char = e;code = 101
char = .;code = 46
char = ;code = 32
char = A;code = 65
char = t;code = 116
char = y;code = 121
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char = i;code = 105
char = c;code = 99
char = a;code = 97
char = l;code = 108
char = ;code = 32
char = c;code = 99
char = a;code = 97
char = r;code = 114
char = c;code = 99
char = i;code = 105
char = n;code = 110
char = o;code = 111
char = i;code = 105
char = d;code = 100
char = ;code = 32
char = h;code = 104
char = a;code = 97
char = d;code = 100
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char = m;code = 109
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char = d;code = 100
char = e;code = 101
char = r;code = 114
char = a;code = 97
char = t;code = 116
char = e;code = 101
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char = u;code = 117
char = p;code = 112
char = t;code = 116
char = a;code = 97
char = k;code = 107
char = e;code = 101
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = (;code = 40
char = 1;code = 49
char = 8;code = 56
char = );code = 41
char = F;code = 70
char = -;code = 45
char = F;code = 70
char = D;code = 68
char = G;code = 71
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char = a;code = 97
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char = d;code = 100
char = ;code = 32
char = h;code = 104
char = i;code = 105
char = g;code = 103
char = h;code = 104
char = ;code = 32
char = (;code = 40
char = 6;code = 54
char = 8;code = 56
char = );code = 41
char = G;code = 71
char = a;code = 97
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char = D;code = 68
char = O;code = 79
char = T;code = 84
char = A;code = 65
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char = T;code = 84
char = O;code = 79
char = C;code = 67
char = ;code = 32
char = u;code = 117
char = p;code = 112
char = t;code = 116
char = a;code = 97
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char = e;code = 101
char = .;code = 46
char = ;code = 32
char = I;code = 73
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char = f;code = 102
char = l;code = 108
char = a;code = 97
char = m;code = 109
char = m;code = 109
char = a;code = 97
char = t;code = 116
char = o;code = 111
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char = y;code = 121
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char = f;code = 102
char = i;code = 105
char = b;code = 98
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char = b;code = 98
char = l;code = 108
char = a;code = 97
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char = i;code = 105
char = c;code = 99
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char = t;code = 116
char = u;code = 117
char = m;code = 109
char = o;code = 111
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char = ;code = 32
char = s;code = 115
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char = o;code = 111
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char = e;code = 101
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char = i;code = 105
char = g;code = 103
char = h;code = 104
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char = u;code = 117
char = p;code = 112
char = t;code = 116
char = a;code = 97
char = k;code = 107
char = e;code = 101
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = (;code = 40
char = 1;code = 49
char = 8;code = 56
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char = F;code = 70
char = -;code = 45
char = F;code = 70
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char = G;code = 71
char = ;code = 32
char = a;code = 97
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char = d;code = 100
char = ;code = 32
char = n;code = 110
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char = u;code = 117
char = p;code = 112
char = t;code = 116
char = a;code = 97
char = k;code = 107
char = e;code = 101
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = (;code = 40
char = 6;code = 54
char = 8;code = 56
char = );code = 41
char = G;code = 71
char = a;code = 97
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char = D;code = 68
char = O;code = 79
char = T;code = 84
char = A;code = 65
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char = T;code = 84
char = O;code = 79
char = C;code = 67
char = .;code = 46
char = ;code = 32
char = M;code = 77
char = u;code = 117
char = c;code = 99
char = o;code = 111
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char = p;code = 112
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char = d;code = 100
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char = m;code = 109
char = o;code = 111
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char = d;code = 100
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char = c;code = 99
char = a;code = 97
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char = c;code = 99
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char = n;code = 110
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char = m;code = 109
char = a;code = 97
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char = e;code = 101
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char = m;code = 109
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char = l;code = 108
char = d;code = 100
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char = 1;code = 49
char = 8;code = 56
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char = F;code = 70
char = -;code = 45
char = F;code = 70
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char = G;code = 71
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char = u;code = 117
char = p;code = 112
char = t;code = 116
char = a;code = 97
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char = n;code = 110
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char = (;code = 40
char = 6;code = 54
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char = );code = 41
char = G;code = 71
char = a;code = 97
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char = D;code = 68
char = O;code = 79
char = T;code = 84
char = A;code = 65
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char = T;code = 84
char = O;code = 79
char = C;code = 67
char = ;code = 32
char = u;code = 117
char = p;code = 112
char = t;code = 116
char = a;code = 97
char = k;code = 107
char = e;code = 101
char = .;code = 46
char = ;code = 32
char = H;code = 72
char = a;code = 97
char = m;code = 109
char = a;code = 97
char = r;code = 114
char = t;code = 116
char = o;code = 111
char = m;code = 109
char = a;code = 97
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char = s;code = 115
char = h;code = 104
char = o;code = 111
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char = e;code = 101
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char = n;code = 110
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char = u;code = 117
char = p;code = 112
char = t;code = 116
char = a;code = 97
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char = e;code = 101
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char = o;code = 111
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char = e;code = 101
char = i;code = 105
char = t;code = 116
char = h;code = 104
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char = c;code = 99
char = a;code = 97
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char = .;code = 46
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char = S;code = 83
char = y;code = 121
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char = o;code = 111
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char = i;code = 105
char = a;code = 97
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char = c;code = 99
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char = l;code = 108
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char = c;code = 99
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char = a;code = 97
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char = o;code = 111
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char = a;code = 97
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char = e;code = 101
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char = 1;code = 49
char = 8;code = 56
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char = F;code = 70
char = -;code = 45
char = F;code = 70
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char = t;code = 116
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char = o;code = 111
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char = a;code = 97
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char = (;code = 40
char = 6;code = 54
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char = G;code = 71
char = a;code = 97
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char = D;code = 68
char = O;code = 79
char = T;code = 84
char = A;code = 65
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char = T;code = 84
char = O;code = 79
char = C;code = 67
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char = u;code = 117
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char = t;code = 116
char = a;code = 97
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char = e;code = 101
char = .;code = 46
char = <;code = 60
char = b;code = 98
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char = >;code = 62
char = <;code = 60
char = b;code = 98
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char = /;code = 47
char = >;code = 62
char = <;code = 60
char = b;code = 98
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char = C;code = 67
char = O;code = 79
char = N;code = 78
char = C;code = 67
char = L;code = 76
char = U;code = 85
char = S;code = 83
char = I;code = 73
char = O;code = 79
char = N;code = 78
char = ;code = 32
char = :;code = 58
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char = <;code = 60
char = /;code = 47
char = b;code = 98
char = >;code = 62
char = T;code = 84
char = h;code = 104
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char = s;code = 115
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char = t;code = 116
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char = a;code = 97
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char = c;code = 99
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char = w;code = 119
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char = s;code = 115
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char = o;code = 111
char = f;code = 102
char = ;code = 32
char = (;code = 40
char = 1;code = 49
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char = F;code = 70
char = -;code = 45
char = F;code = 70
char = D;code = 68
char = G;code = 71
char = ;code = 32
char = a;code = 97
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char = (;code = 40
char = 6;code = 54
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char = );code = 41
char = G;code = 71
char = a;code = 97
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char = D;code = 68
char = O;code = 79
char = T;code = 84
char = A;code = 65
char = -;code = 45
char = T;code = 84
char = O;code = 79
char = C;code = 67
char = ;code = 32
char = P;code = 80
char = E;code = 69
char = T;code = 84
char = -;code = 45
char = C;code = 67
char = T;code = 84
char = ;code = 32
char = s;code = 115
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char = a;code = 97
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char = v;code = 118
char = e;code = 101
char = a;code = 97
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char = d;code = 100
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char = f;code = 102
char = f;code = 102
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char = t;code = 116
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char = u;code = 117
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char = t;code = 116
char = a;code = 97
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char = e;code = 101
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char = a;code = 97
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char = i;code = 105
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char = i;code = 105
char = o;code = 111
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char = s;code = 115
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char = b;code = 98
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char = c;code = 99
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char = a;code = 97
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char = t;code = 116
char = u;code = 117
char = m;code = 109
char = o;code = 111
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char = .;code = 46
char = ;code = 32
char = B;code = 66
char = r;code = 114
char = o;code = 111
char = n;code = 110
char = c;code = 99
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result sql = OBJECTIVE : To evaluate the role of combination of (18)F-FDG PET-CT scan and (68)Ga DOTA-TOC PET-CT scan in differentiating bronchial tumors observed in contrast enhanced computed tomography scan of chest. Study design: Prospective observational study. Place of study: All India Institute of Medical Sciences, New Delhi, India.

METHODS : 7 patients with bronchial mass detected in computed tomography scan of the chest were included in this study. All patients underwent (18)F-FDG PET-CT scan, (68)Ga DOTA-TOC PET-CT scan and fiberoptic bronchoscope guided biopsy followed by definitive surgical excision. The results of functional imaging studies were analyzed and the results are correlated with the final histopathology of the tumor.

RESULTS : Histopathological examination of 7 bronchial masses revealed carcinoid tumors (2 typical, 1 atypical), inflammatory myofibroblastic tumor (1), mucoepidermoid carcinoma (1), hamartoma (1), and synovial cell sarcoma (1). The typical carcinoids had mild (18)F-FDG uptake and high (68)Ga DOTA-TOC uptake. Atypical carcinoid had moderate uptake of (18)F-FDG and high (68)Ga DOTA-TOC uptake. Inflammatory myofibroblastic tumor showed high uptake of (18)F-FDG and no uptake of (68)Ga DOTA-TOC. Mucoepidermoid carcinoma showed mild (18)F-FDG uptake and no (68)Ga DOTA-TOC uptake. Hamartoma showed no uptake on either scans. Synovial cell sarcoma showed moderate (18)F-FDG uptake and mild focal (68)Ga DOTA-TOC uptake.

CONCLUSION : This initial experience with the combined use of (18)F-FDG and (68)Ga DOTA-TOC PET-CT scan reveals different uptake patterns in various bronchial tumors. Bronchoscopic biopsy will continue to be the gold standard; however, the interesting observations made in this study merits further evaluation of the utility of the combination of (18)F-FDG PET-CT scan and (68)Ga DOTA-TOC PET-CT scan in larger number of patients with bronchial masses.

Publication: Ann Nucl Med 2009 Oct ;23(8)::745-51. :doi: 10.1007/s12149-009-0302-0.
Publication Date: 2009 Oct
Study Author(s): Kumar, Arvind;Jindal, Tarun;Dutta, Roman;Kumar, Rakesh;
Institution: Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, 110029, India. [email protected]
Shortcut link to this study:
OBJECTIVE : To evaluate the role of combination of (18)F-FDG PET-CT scan and (68)Ga DOTA-TOC PET-CT scan in differentiating bronchial tumors observed in contrast enhanced computed tomography scan of chest. Study design: Prospective observational study. Place of study: All India Institute of Medical Sciences, New Delhi, India.

METHODS : 7 patients with bronchial mass detected in computed tomography scan of the chest were included in this study. All patients underwent (18)F-FDG PET-CT scan, (68)Ga DOTA-TOC PET-CT scan and fiberoptic bronchoscope guided biopsy followed by definitive surgical excision. The results of functional imaging studies were analyzed and the results are correlated with the final histopathology of the tumor.

RESULTS : Histopathological examination of 7 bronchial masses revealed carcinoid tumors (2 typical, 1 atypical), inflammatory myofibroblastic tumor (1), mucoepidermoid carcinoma (1), hamartoma (1), and synovial cell sarcoma (1). The typical carcinoids had mild (18)F-FDG uptake and high (68)Ga DOTA-TOC uptake. Atypical carcinoid had moderate uptake of (18)F-FDG and high (68)Ga DOTA-TOC uptake. Inflammatory myofibroblastic tumor showed high uptake of (18)F-FDG and no uptake of (68)Ga DOTA-TOC. Mucoepidermoid carcinoma showed mild (18)F-FDG uptake and no (68)Ga DOTA-TOC uptake. Hamartoma showed no uptake on either scans. Synovial cell sarcoma showed moderate (18)F-FDG uptake and mild focal (68)Ga DOTA-TOC uptake.

CONCLUSION : This initial experience with the combined use of (18)F-FDG and (68)Ga DOTA-TOC PET-CT scan reveals different uptake patterns in various bronchial tumors. Bronchoscopic biopsy will continue to be the gold standard; however, the interesting observations made in this study merits further evaluation of the utility of the combination of (18)F-FDG PET-CT scan and (68)Ga DOTA-TOC PET-CT scan in larger number of patients with bronchial masses.
PMID: 19784877

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